Association of the osteoprotegerin gene polymorphisms with bone mineral density in postmenopausal women

Maturitas

Volumn 51, Issue 3, 2005, Pages 270-279

  Arko, Barbara ^a   Preželj, Janez ^b   Kocijančič, Andreja ^b   Komel, Radovan ^b   Marc, Janja ^a  

^a UNIVERSITY OF LJUBLJANA   (Slovenia)

^b UNIVERSITY MEDICAL CENTRE LJUBLJANA   (Slovenia)

Author keywords

Bone mineral density; Heteroduplex analysis; Osteoporosis; Osteoprotegerin gene polymorphism; RFLP analysis; SSCP analysis

Indexed keywords

DNA; NUCLEOTIDE; OSTEOPROTEGERIN;

ADULT; AGED; ARTICLE; BONE DENSITY; CONTROLLED STUDY; DNA SEQUENCE; FEMALE; GENETIC ASSOCIATION; GENETIC CODE; GENETIC LINKAGE; GENETIC POLYMORPHISM; GENETIC SCREENING; GENETIC SUSCEPTIBILITY; GENOTYPE; HUMAN; LUMBAR SPINE; MAJOR CLINICAL STUDY; NUCLEOTIDE SEQUENCE; OSTEOPOROSIS; POSTMENOPAUSE; SINGLE STRAND CONFORMATION POLYMORPHISM;

AGED; BONE DENSITY; DNA; FEMALE; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; GLYCOPROTEINS; HETERODUPLEX ANALYSIS; HUMANS; MIDDLE AGED; OSTEOPOROSIS, POSTMENOPAUSAL; OSTEOPROTEGERIN; POLYMERASE CHAIN REACTION; POLYMORPHISM, GENETIC; POLYMORPHISM, RESTRICTION FRAGMENT LENGTH; POLYMORPHISM, SINGLE-STRANDED CONFORMATIONAL; POSTMENOPAUSE; RECEPTORS, CYTOPLASMIC AND NUCLEAR; RECEPTORS, TUMOR NECROSIS FACTOR;

EID: 20644444997     PISSN: 03785122     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.maturitas.2004.08.006     Document Type: Article

References (35)

1. Consensus development conference: diagnosis, prophylaxis, and treatment of osteoporosis. Am J Med 1993; 94: 646-50.
2. M. Peacock, C. Turner, M. Econs, and T. Foroud Genetics of osteoporosis Endocr. Rev. 23 2002 303 326
3. S.H. Ralston Genetic control of susceptibility to osteoporosis J. Clin. Endocrinol. Metab. 87 2002 2460 2466
4. R. Rizzoli, J.P. Bonjour, and S.L. Ferrari Osteoporosis, genetics and hormones J. Mol. Endocrinol. 26 2001 79 94
5. W.S. Simonet, D.L. Lacey, and C.R. Dunstan Osteoprotegerin: a novel secreted protein involved in the regulation of bone density Cell 89 1997 309 319
6. K.B. Tan, J. Harrop, and M. Reddy Characterization of a novel TNF-like ligand and recently described TNF ligand and TNF receptor superfamily genes and their constitutive and inducible expression in hematopoietic and non-hematopoietic cells Gene 204 1997 35 46
7. E. Tsuda, M. Goto, and S. Mochizuki Isolation of a novel cytokine from human fibroblasts that specifically inhibits osteoclastogenesis Biochem. Biophys. Res. Commun. 234 1997 137 142
8. H. Yasuda, N. Shima, and N. Nakagawa Identity of osteoclastogenesis inhibitory factor (OCIF) and osteoprotegerin (OPG): a mechanism by which OPG/OCIF inhibits osteoclastogenesis in vitro Endocrinology 139 1998 1329 1337
9. B.S. Kwon, S. Wang, and N. Udagawa TR1, a new member of the tumor necrosis factor receptor superfamily, induces fibroblast proliferation and inhibits osteoclastogenesis and bone resorption FASEB J. 12 1998 845 854
10. D.L. Lacey, E. Timms, and H.L. Tan Osteoprotegerin ligand is a cytokine that regulates osteoclast differentiation and activation Cell 93 1998 165 176
11. T.L. Burgess, Y. Qian, and S. Kaufman The ligand for osteoprotegerin (OPGL) directly activates mature osteoclasts J. Cell Biol. 145 1999 527 538
12. Y. Hakeda, Y. Kobayashi, and K. Yamaguchi Osteoclastogenesis inhibitory factor (OCIF) directly inhibits bone- resorbing activity of isolated mature osteoclasts Biochem. Biophys. Res. Commun. 251 1998 796 801
13. T. Akatsu, T. Murakami, and M. Nishikawa Osteoclastogenesis inhibitory factor suppresses osteoclast survival by interfering in the interaction of stromal cells with osteoclast Biochem. Biophys. Res. Commun. 250 1998 229 234
14. K. Fuller, B. Wong, S. Fox, Y. Choi, and T.J. Chambers TRANCE is necessary and sufficient for osteoblast-mediated activation of bone resorption in osteoclasts J. Exp. Med. 188 1998 997 1001
15. A. Mizuno, N. Amizuka, and K. Irie Severe osteoporosis in mice lacking osteoclastogenesis inhibitory factor/osteoprotegerin Biochem. Biophys. Res. Commun. 247 1998 610 615
16. N. Bucay, I. Sarosi, and C.R. Dunstan osteoprotegerin-deficient mice develop early onset osteoporosis and arterial calcification Genes Dev. 12 1998 1260 1268
17. P.J. Bekker, D. Holloway, A. Nakanishi, M. Arrighi, P.T. Leese, and C.R. Dunstan The effect of a single dose of osteoprotegerin in postmenopausal women J. Bone Miner. Res. 16 2001 348 360
18. T. Cundy, M. Hegde, and D. Naot A mutation in the gene TNFRSF11B encoding osteoprotegerin causes an idiopathic hyperphosphatasia phenotype Hum. Mol. Genet. 11 2002 2119 2127
19. M.P. Whyte, S.E. Obrecht, and P.M. Finnegan Osteoprotegerin deficiency and juvenile Paget's disease N. Engl. J. Med. 347 2002 175 184
20. T. Morinaga, N. Nakagawa, H. Yasuda, E. Tsuda, and K. Higashio Cloning and characterization of the gene encoding human osteoprotegerin/ osteoclastogenesis-inhibitory factor Eur. J. Biochem. 254 1998 685 691
21. B. Arko, J. Preželj, R. Komel, A. Kocijančič, P. Hudler, and J. Marc Sequence variations in the osteoprotegerin gene promoter in patients with postmenopausal osteoporosis J. Clin. Endocrinol. Metab. 87 2002 4080 4084
22. S.A. Miller, D.D. Dykes, and H.F. Polesky A simple salting out procedure for extracting DNA from human nucleated cells Nucleic Acids Res. 16 1988 1215
23. B.L. Langdahl, M. Carstens, L. Stenkjaer, and E.F. Eriksen Polymorphisms in the osteoprotegerin gene are associated with osteoporotic fractures J. Bone Miner. Res. 17 2002 1245 1255
24. F. Wynne, F. Drummond, and K. O'Sullivan Investigation of the Genetic Influence of the OPG, VDR (Fok1), and COLIA1 Sp1 Polymorphisms on BMD in the Irish Population Calcif. Tissue Int. 71 2002 26 35
25. H. Ohmori, Y. Makita, and M. Funamizu Linkage and association analyses of the osteoprotegerin gene locus with human osteoporosis J. Hum. Genet. 47 2002 400 406
26. A. Arnold, S.A. Horst, T.J. Gardella, H. Baba, M.A. Levine, and H.M. Kronenberg Mutation of the signal peptide-encoding region of the preproparathyroid hormone gene in familial isolated hypoparathyroidism J. Clin. Invest. 86 1990 1084 1087
27. A.C. Karaplis, S.K. Lim, H. Baba, A. Arnold, and H.M. Kronenberg Inefficient membrane targeting, translocation, and proteolytic processing by signal peptidase of a mutant preproparathyroid hormone protein J. Biol. Chem. 270 1995 1629 1635
28. M. Racchi, H.H. Watzke, K.A. High, and M.O. Lively Human coagulation factor X deficiency caused by a mutant signal peptide that blocks cleavage by signal peptidase but not targeting and translocation to the endoplasmic reticulum J. Biol. Chem. 268 1993 5735 5740
29. M. Ito, Y. Oiso, and T. Murase Possible involvement of inefficient cleavage of preprovasopressin by signal peptidase as a cause for familial central diabetes insipidus J. Clin. Invest. 91 1993 2565 2571
30. J. Seppen, E. Steenken, D. Lindhout, P.J. Bosma, and R.P. Elferink A mutation which disrupts the hydrophobic core of the signal peptide of bilirubin UDP-glucuronosyltransferase, an endoplasmic reticulum membrane protein, causes Crigler-Najjar type II FEBS Lett. 390 1996 294 298
31. H. Brändström, P. Gerdhem, and F. Stiger Single nucleotide polymorphisms in the human gene for osteoprotegerin are not related to bone mineral density or fracture in elderly women Calcif. Tissue Int. 74 2003 18 24
32. L. Gennari, L. Becherini, A. Falchetti, L. Masi, F. Massart, and M.L. Brandi Genetics of osteoporosis: role of steroid hormone receptor gene polymorphisms J. Steroid Biochem. Mol. Biol. 81 2002 1 24
33. Y. Giguere, and F. Rousseau The genetics of osteoporosis: 'complexities and difficulties' Clin Genet. 57 2000 161 169
34. J. Marc, J. Preželj, R. Komel, and A. Kocijančič Association of vitamin D receptor gene polymorphism with bone mineral density in Slovenian postmenopausal women Gynecol. Endocrinol. 14 2000 60 64
35. H.W. Deng, J. Li, J.L. Li, M. Johnson, G. Gong, and R.R. Recker Association of VDR and estrogen receptor genotypes with bone mass in postmenopausal Caucasian women: different conclusions with different analyses and the implications Osteoporos Int. 9 1999 499 507