Structural and functional characterization of human Iba proteins

FEBS Journal

Volumn 275, Issue 18, 2008, Pages 4627-4640

  Schulze, Jörg O ^a   Quedenau, Claudia ^b   Roske, Yvette ^a   Adam, Thomas ^c   Schüler, Herwig ^a   Behlke, Joachim ^a   Turnbull, Andrew P ^a   Sievert, Volker ^b   Scheich, Christoph ^b   Mueller, Uwe ^d   Heinemann, Udo ^a,e   Büssow, Konrad ^b,f  

^a MAX DELBRÜCK CENTER FOR MOLECULAR MEDICINE   (Germany)

^b MAX PLANCK INSTITUTE FOR MOLECULAR GENETICS   (Germany)

^c CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

^d HAHN MEITNER INSTITUT   (Germany)

^e FREIE UNIVERSITÄT BERLIN   (Germany)

^f HELMHOLTZ CENTRE FOR INFECTION RESEARCH   (Germany)

Author keywords

Actin cross linking; Allograft inflammatory factor 1; Calcium binding; EF hand; Ionized calcium binding adapter molecule

Indexed keywords

DISULFIDE; F ACTIN; HYBRID PROTEIN; IONIZED CALCIUM BINDING ADAPTER MOLECULE 1; ZINC ION;

ARTICLE; CALCIUM BINDING; CELLULAR DISTRIBUTION; CRYSTAL STRUCTURE; CRYSTALLIZATION; DIMERIZATION; EQUILIBRIUM DIALYSIS; HELA CELL; HUMAN; HUMAN CELL; MICROSCOPY; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN STRUCTURE; ULTRACENTRIFUGATION;

ACTINS; AMINO ACID SEQUENCE; CALCIUM; CALCIUM-BINDING PROTEINS; CRYSTALLOGRAPHY, X-RAY; DIMERIZATION; DNA-BINDING PROTEINS; HELA CELLS; HUMANS; MICROFILAMENT PROTEINS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; SEQUENCE ALIGNMENT; SHIGELLA;

BACTERIA (MICROORGANISMS); SHIGELLA;

EID: 50849112730     PISSN: 1742464X     EISSN: 17424658     Source Type: Journal    
DOI: 10.1111/j.1742-4658.2008.06605.x     Document Type: Article

References (54)

1. Imai Y, Ibata I, Ito D, Ohsawa K Kohsaka S (1996) A novel gene iba1 in the major histocompatibility complex class III region encoding an EF hand protein expressed in a monocytic lineage. Biochem Biophys Res Commun 224, 855 862.
2. Kawasaki H, Nakayama S Kretsinger RH (1998) Classification and evolution of EF-hand proteins. Biometals 11, 277 295.
3. Ohsawa K, Imai Y, Kanazawa H, Sasaki Y Kohsaka S (2000) Involvement of Iba1 in membrane ruffling and phagocytosis of macrophages/microglia. J Cell Sci 113, 3073 3084.
4. Yamada M, Ohsawa K, Imai Y, Kohsaka S Kamitori S (2006) X-Ray structures of the microglia/macrophage-specific protein Iba1 from human and mouse demonstrate novel molecular conformation change induced by calcium binding. J Mol Biol 364, 449 457.
5. Shyamsundar R, Kim YH, Higgins JP, Montgomery K, Jorden M, Sethuraman A, van de Rijn M, Botstein D, Brown PO Pollack JR (2005) A DNA microarray survey of gene expression in normal human tissues. Genome Biol 6, R22.
6. Autieri MV (1996) cDNA cloning of human allograft inflammatory factor-1: tissue distribution, cytokine induction, and mRNA expression in injured rat carotid arteries. Biochem Biophys Res Commun 228, 29 37.
7. Utans U, Arceci RJ, Yamashita Y Russell ME (1995) Cloning and characterization of allograft inflammatory factor-1: a novel macrophage factor identified in rat cardiac allografts with chronic rejection. J Clin Invest 95, 2954 2962.
8. Utans U, Quist WC, McManus BM, Wilson JE, Arceci RJ, Wallace AF Russell ME (1996) Allograft inflammatory factory-1. A cytokine-responsive macrophage molecule expressed in transplanted human hearts. Transplantation 61, 1387 1392.
9. Autieri MV, Carbone C Mu A (2000) Expression of allograft inflammatory factor-1 is a marker of activated human vascular smooth muscle cells and arterial injury. Arterioscler Thromb Vasc Biol 20, 1737 1744.
10. Köhler C (2007) Allograft inflammatory factor-1/ionized calcium-binding adapter molecule 1 is specifically expressed by most subpopulations of macrophages and spermatids in testis. Cell Tissue Res 330, 291 302.
11. Autieri MV, Kelemen SE Wendt KW (2003) AIF-1 is an actin-polymerizing and Rac1-activating protein that promotes vascular smooth muscle cell migration. Circ Res 92, 1107 1114.
12. Sasaki Y, Ohsawa K, Kanazawa H, Kohsaka S Imai Y (2001) Iba1 is an actin-cross-linking protein in macrophages/microglia. Biochem Biophys Res Commun 286, 292 297.
13. Ohsawa K, Imai Y, Sasaki Y Kohsaka S (2004) Microglia/macrophage-specific protein Iba1 binds to fimbrin and enhances its actin-bundling activity. J Neurochem 88, 844 856.
14. Büssow K, Scheich C, Sievert V, Harttig U, Schultz J, Simon B, Bork P, Lehrach H Heinemann U (2005) Structural genomics of human proteins - target selection and generation of a public catalog of expression clones. Microb Cell Fact 4, 21.
15. Wiemann S, Weil B, Wellenreuther R, Gassenhuber J, Glassl S, Ansorge W, Böcher M, Blöcker H, Bauersachs S, Blum H et al. (2001) Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs. Genome Res 11, 422 435.
16. Bannasch D, Mehrle A, Glatting KH, Pepperkok R, Poustka A Wiemann S (2004) LIFEdb: a database for functional genomics experiments integrating information from external sources, and serving as a sample tracking system. Nucleic Acids Res 32, D505 D508.
17. Simpson JC, Wellenreuther R, Poustka A, Pepperkok R Wiemann S (2000) Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing. EMBO Reports 1, 287 292.
18. Grabarek Z (2006) Structural basis for diversity of the EF-hand calcium-binding proteins. J Mol Biol 359, 509 525.
19. Chattopadhyaya R, Meador WE, Means AR Quiocho FA (1992) Calmodulin structure refined at 1.7 Å resolution. J Mol Biol 228, 1177 1192.
20. Rao ST, Satyshur KA, Greaser ML Sundaralingam M (1996) X-ray structures of Mn, Cd and Tb metal complexes of troponin C. Acta Crystallogr D Biol Crystallogr 52, 916 922.
21. Tang JX Janmey PA (1998) Two distinct mechanisms of actin bundle formation. Biol Bull 194, 406 408.
22. Adam T, Arpin M, Prevost MC, Gounon P Sansonetti PJ (1995) Cytoskeletal rearrangements and the functional role of T-plastin during entry of Shigella flexneri into HeLa cells. J Cell Biol 129, 367 381.
23. Jones S Thornton JM (1996) Principles of protein-protein interactions. Proc Natl Acad Sci USA 93, 13 20.
24. Banatao DR, Cascio D, Crowley CS, Fleissner MR, Tienson HL Yeates TO (2006) An approach to crystallizing proteins by synthetic symmetrization. Proc Natl Acad Sci USA 103, 16230 16235.
25. Autieri MV Chen X (2005) The ability of AIF-1 to activate human vascular smooth muscle cells is lost by mutations in the EF-hand calcium-binding region. Exp Cell Res 307, 204 211.
26. 2+-binding helix-loop-helix EF-hand motifs. Biochem J 405, 199 221.
27. Brodersen DE, Etzerodt M, Madsen P, Celis JE, Thøgersen HC, Nyborg J Kjeldgaard M (1998) EF-hands at atomic resolution: the structure of human psoriasin (S100A7) solved by MAD phasing. Structure 6, 477 489.
28. Lewit-Bentley A Rety S (2000) EF-hand calcium-binding proteins. Curr Opin Struct Biol 10, 637 643.
29. Graf B, Bähler M, Hilpelä P, Böwe C Adam T (2000) Functional role for the class IX myosin myr5 in epithelial cell infection by Shigella flexneri. Cell Microbiol 2, 601 616.
30. Adam T, Giry M, Boquet P Sansonetti P (1996) Rho-dependent membrane folding causes Shigella entry into epithelial cells. EMBO J 15, 3315 3321.
31. Mounier J, Laurent V, Hall A, Fort P, Carlier MF, Sansonetti PJ Egile C (1999) Rho family GTPases control entry of Shigella flexneri into epithelial cells but not intracellular motility. J Cell Sci 112, 2069 2080.
32. Tran Van Nhieu G, Caron E, Hall A Sansonetti PJ (1999) IpaC induces actin polymerization and filopodia formation during Shigella entry into epithelial cells. EMBO J 18, 3249 3262.
33. Kanazawa H, Ohsawa K, Sasaki Y, Kohsaka S Imai Y (2002) Macrophage/microglia-specific protein Iba1 enhances membrane ruffling and Rac activation via phospholipase C-gamma-dependent pathway. J Biol Chem 277, 20026 20032.
34. Tian Y Autieri MV (2007) Cytokine expression and AIF-1-mediated activation of Rac2 in vascular smooth muscle cells: a role for Rac2 in VSMC activation. Am J Physiol 292, C841 C849.
35. Novy R, Drott D, Yaeger K Mierendorf R (2001) Overcoming the codon bias of E. coli for enhanced protein expression. inNovations 12, 1 3.
36. Matthews BW (1968) Solvent content of protein crystals. J Mol Biol 33, 491 497.
37. Heinemann U, Büssow K, Mueller U Umbach P (2003) Facilities and methods for the high-throughput crystal structural analysis of human proteins. Acc Chem Res 36, 157 163.
38. Kabsch W (1993) Automatic processing of rotation diffraction data from crystals of initially unknown symmetry and cell constants. J Appl Crystallogr 26, 795 800.
39. Collaborative Computational Project N (1994) The CCP4 suite: programs for protein crystallography. Acta Crystallogr D Biol Crystallogr 50, 760 763.
40. McCoy AJ, Grosse-Kunstleve RW, Storoni LC Read RJ (2005) Likelihood-enhanced fast translation functions. Acta Crystallogr D Biol Crystallogr 61, 458 464.
41. Brünger AT, Adams PD, Clore GM, DeLano WL, Gros P, Grosse-Kunstleve RW, Jiang JS, Kuszewski J, Nilges M, Pannu NS et al. (1998) Crystallography & NMR system: a new software suite for macromolecular structure determination. Acta Crystallogr D Biol Crystallogr 54, 905 921.
42. Murshudov GN, Vagin AA Dodson EJ (1997) Refinement of macromolecular structures by the maximum-likelihood method. Acta Crystallogr D Biol Crystallogr 53, 240 255.
43. Emsley P Cowtan K (2004) Coot: model-building tools for molecular graphics. Acta Crystallogr D Biol Crystallogr 60, 2126 2132.
44. Vriend G (1990) WHAT IF: a molecular modeling and drug design program. J Mol Graphics 8, 52 56, 29.
45. Laskowski RA, MacArthur MW, Moss DS Thornton JM (1993) PROCHECK: a program to check the stereochemical quality of protein structures. J Appl Crystallogr 26, 283 291.
46. DeLano WL (2002) The PyMOL User's Manual. DeLano Scientific, San Carlos, CA.
47. Holm L Sander C (1996) Mapping the protein universe. Science 273, 595 603.
48. Lindberg U, Schutt CE, Hellsten E, Tjader AC Hult T (1988) The use of poly(l-proline)-Sepharose in the isolation of profilin and profilactin complexes. Biochim Biophys Acta 967, 391 400.
49. Schüler H, Karlsson R Lindberg U (2005) Purification of non-muscle actin. In Cell Biology: A Laboratory Handbook (Celis J, ed.), pp. 165-171. Academic Press, New York, NY.
50. Schüler H Peti W (2008) Structure-function analysis of the filamentous actin binding domain of the neuronal scaffolding protein spinophilin. FEBS J 275, 59 68.
51. Stevens J Rogers JH (1997) Chick calretinin: purification, composition, and metal binding activity of native and recombinant forms. Protein Express Purif 9, 171 181.
52. Behlke J, Ristau O Schönfeld HJ (1997) Nucleotide-dependent complex formation between the Escherichia coli chaperonins GroEL and GroES studied under equilibrium conditions. Biochemistry 36, 5149 5156.
53. Sambrook J, Fritsch EF Maniatis T (1989) Molecular Cloning: A Laboratory Manual, 2nd edn. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY.
54. Clerc P Sansonetti PJ (1987) Entry of Shigella flexneri into HeLa cells: evidence for directed phagocytosis involving actin polymerization and myosin accumulation. Infect Immun 55, 2681 2688.