Functional role for the class IX myosin myr5 in epithelial cell infection by Shigella flexneri

Cellular Microbiology

Volumn 2, Issue 6, 2000, Pages 601-616

  Graf, Barbara ^a   Bähler, Martin ^b   Hilpelä, Pirta ^b   Böwe, Christian ^a   Adam, Thomas ^a  

^a HUMBOLDT UNIVERSITY   (Germany)

^b UNIVERSITY OF MÜNSTER   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

EZRIN; GUANOSINE TRIPHOSPHATASE ACTIVATING PROTEIN; MUTANT PROTEIN; MYOSIN; MYOSIN CLASS IX; PROTEIN CDC42; PROTEIN MYR5; RAC PROTEIN; RHOA GUANINE NUCLEOTIDE BINDING PROTEIN; RHOB GUANINE NUCLEOTIDE BINDING PROTEIN; RHOC GUANINE NUCLEOTIDE BINDING PROTEIN; UNCLASSIFIED DRUG;

ARTICLE; BACTERIUM ADHERENCE; CELL INVASION; CELL STRUCTURE; CONTROLLED STUDY; CYTOSKELETON; ENZYME ACTIVITY; EPITHELIUM CELL; HUMAN; HUMAN CELL; INTERNALIZATION; NONHUMAN; PRIORITY JOURNAL; SHIGELLA FLEXNERI;

CDC42 GTP-BINDING PROTEIN; CYTOSKELETAL PROTEINS; DYSENTERY, BACILLARY; FLUORESCENT ANTIBODY TECHNIQUE; HELA CELLS; HUMANS; MYOSINS; PHOSPHOPROTEINS; RAC GTP-BINDING PROTEINS; RHO GTP-BINDING PROTEINS; SHIGELLA FLEXNERI;

BACTERIA (MICROORGANISMS); SHIGELLA; SHIGELLA FLEXNERI;

EID: 0034519957     PISSN: 14625814     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1462-5822.2000.00084.x     Document Type: Article

References (39)

1. A role for the small GTPase rho in epithelial cell invasion by Shigella
2. Cytoskeletal rearrangements and the functional role of T-plastin during entry of Shigella flexneri into HeLa cells
3. Rhodependent membrane folding causes Shigella entry into epithelial cells
4. Physical mapping of human myosin-IXB (MYO9B), the human orthologue of the rat myosin myr 5, to chromosome 19p 13.1
5. Functions of the myosin ATP and actin binding sites are required for C. elegans thick filament assembly
6. Regulation of cortical structure by the ezrinradixin-moesin protein family
7. Superresolution threedimensional images of fluorescence in cells with minimal light exposure
8. The small GTP-binding protein rho regulates a phosphatidyinositol 4-phosphate 5-kinase in mammalian cells
9. Entry of Shigella flexneri into HeLa cells: Evidence for directed phagocytosis involving actin polymerization and myosin accumulation
10. Evidence for clathrin mobilization during directed phagocytosis of Shigella flexneri by HEp2 cells
11. Src tyrosine kinase activity down-regulates rho-dependent responses during Shigella entry into epithelial cells and stress fiber formation
12. Tight control of gene expression in mammalian cells by tetracycline-responsive promoters
13. The ras-related gene rhoB is an immediate-early gene inducible by v-Fps, epidermal growth factor, and platelet-derived growth factor in rat fibroblasts
14. Rho regulates association of both the ERM family and vinculin with the plasma membrane in MDCK cells
15. Cloning and expression of an afimbrial adhesin (AFA-I) responsible for P blood group-independent, mannose-resistant hemagglutination from a pyelonephritic Escherichia coli strain
16. Rhoand rac-dependent assembly of focal adhesion complexes and actin filaments in permeabilized fibroblasts: An essential role for ezrin/radixin/moesin proteins
17. Rho-kinase phosphorylates COOH-terminal threonines of ezrin/radixin/moesin (ERM) proteins and regulates their head-to-tail association
18. Nonpolar mutagenesis of the ipa genes defines lpaB, lpaC, and lpaD as effectors of Shigella flexneri entry into epithelial cells
19. Extracellular association and cytoplasmic partitioning of the IpaB and IpaC invasins of S. flexneri
20. Bacterial entry into epithelial cells: The paradigm of Shigella
21. Rho family GTPases control entry of Shigella flexneri into epithelial cells but not intracellular motility
22. The rat myosin myr 5 is a GTPase-activating protein for Rho in vivo: Essential role of arginine 1695
23. Human myosin-IXb is a mechanochemically active motor and a GAP for rho
24. Phosphatidylinositol 4,5-bisphosphate functions as a second messenger that regulates cytoskeleton-plasma membrane adhesion
25. A novel type of myosin implicated in signalling by rho family GTPases
26. OmpB (osmo-regulation) and icsA (cell-to-cell spread) mutants of Shigella flexneri: Vaccine candidates and probes to study the pathogenesis of shigellosis
27. Metabolic events mediating early killing of host cells infected by Shigella flexneri
28. A functional role for Ezrin during Shigella flexneri entry into epithelial cells
29. Targeting of the myosin-I myr 3 to intercellular adherens type junctions induced by dominant active Cdc42 in HeLa cells
30. Direct interaction of the Rho GDP dissociation inhibitor with ezrin/radixin/moesin initiates the activation of the Rho small G protein
31. Poly (A) RNA codistribution with microfilaments: Evaluation by in situ hybridization and quantitative digital imaging microscopy
32. Modulation of bacterial entry into epithelial cells by association between vinculin and the Shigella IpaA invasin
33. IpaC induces actin polymerization and filopodia formation during Shigella entry into epithelial cells
34. Infection of eucaryotic cells by helper-independent recombinant adeno-viruses: Early region 1 is not obligatory for integration of viral DNA
35. Rho, a small GTP-binding protein, is essential for Shigella invasion of epithelial cells
36. Human myosin-IXb, an unconventional myosin with a chimerin-like rho/rac GTPase-activating protein domain in its tail
37. Transport of myosin II to the equatorial region without its own motor activity in mitotic Dictyostelium cells
38. Myosin II localization during cytokinesis occurs by a mechanism that does not require its motor domain