Role of fibroblast growth factor 8 (FGF8) in animal models of osteoarthritis

Arthritis Research and Therapy

Volumn 10, Issue 4, 2008, Pages

  Uchii, Masako ^a   Tamura, Tadafumi ^a   Suda, Toshio ^a   Kakuni, Masakazu ^a,b   Tanaka, Akira ^c   Miki, Ichiro ^a  

^a KYOWA HAKKO KOGYO CO LTD   (Japan)

^b PhoenixBio USA Corporation   (Japan)

^c JICHI MEDICAL UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

FIBROBLAST GROWTH FACTOR 8; GLYCOSAMINOGLYCAN POLYSULFATE; INTERLEUKIN 1ALPHA; IODOACETIC ACID; MATRIX METALLOPROTEINASE; MONOCLONAL ANTIBODY; PROSTAGLANDIN E2; PROTEINASE; RECOMBINANT FIBROBLAST GROWTH FACTOR; RECOMBINANT FIBROBLAST GROWTH FACTOR 8; STROMELYSIN; A73025; GLYCOSAMINOGLYCAN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CARTILAGE CELL; CARTILAGE DEGENERATION; CELL CULTURE; CELL HYPERPLASIA; CONTROLLED STUDY; DISEASE EXACERBATION; ENZYME RELEASE; ENZYME SYNTHESIS; EXTRACELLULAR MATRIX; FIBROBLAST; IMMUNOHISTOCHEMISTRY; KNEE OSTEOARTHRITIS; MALE; MENISCECTOMY; NONHUMAN; PROSTAGLANDIN RELEASE; PROTEIN ANALYSIS; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN SECRETION; RABBIT; RAT; SYNOVIOCYTE; SYNOVIUM; ANIMAL; ARTICULAR CARTILAGE; CELL PROLIFERATION; CHEMICALLY INDUCED DISORDER; DISEASE MODEL; DRUG EFFECT; INTRAARTICULAR DRUG ADMINISTRATION; METABOLISM; PATHOLOGY; SPRAGUE DAWLEY RAT;

ANIMALS; CARTILAGE, ARTICULAR; CELL PROLIFERATION; CELLS, CULTURED; CHONDROCYTES; DINOPROSTONE; DISEASE MODELS, ANIMAL; EXTRACELLULAR MATRIX; FIBROBLAST GROWTH FACTOR 8; GLYCOSAMINOGLYCANS; INJECTIONS, INTRA-ARTICULAR; IODOACETIC ACID; MALE; MATRIX METALLOPROTEINASE 3; OSTEOARTHRITIS, KNEE; RABBITS; RATS; RATS, SPRAGUE-DAWLEY; SYNOVIAL MEMBRANE;

EID: 50849101663     PISSN: 14786354     EISSN: 14786362     Source Type: Journal    
DOI: 10.1186/ar2474     Document Type: Article

References (41)

1. Pelletier JP Martel-Pelletier J Abramson SB Osteoarthritis, an inflammatory disease: Potential implication for the selection of new therapeutic targets Arthritis Rheum 2001, 44:1237-1247. 11407681
2. Hardy MM Seibert K Manning PT Currie MG Woerner BM Edwards D Koki A Tripp CS Cyclooxygenase 2-dependent prostaglandin E2 modulates cartilage proteoglycan degradation in human osteoarthritis explants Arthritis Rheum 2002, 46:1789-1803. 12124863
3. Lohmander LS Hoerrner LA Lark MW Metalloproteinases, tissue inhibitor, and proteoglycan fragments in knee synovial fluid in human osteoarthritis Arthritis Rheum 1993, 36:181-189. 8431206
4. Okada Y Shinmei M Tanaka O Naka K Kimura A Nakanishi I Bayliss MT Iwata K Nagase H Localization of matrix metalloproteinase 3 (storomelysin) in osteoarthritic cartilage and synovium Lab Invest 1992, 66:680-690. 1602738
5. Nagase H Activation mechanisms of matrix metalloproteinases Biol Chem 1997, 378:151-160. 9165065
6. Tchetverikov I Lohmander LS Verzijl N Huizinga TW TeKoppele JM Hanemaaijer R DeGroot J MMP protein and activity levels in synovial fluid from patients with joint injury, inflammatory arthritis, and osteoarthritis Ann Rheum Dis 2005, 64:694-698. 1755474 15834054
7. Szebenyi G Fallon JF Fibroblast growth factors as multifunctional signaling factors Int Rev Cytol 1999, 185:45-106. 9750265
8. Draper BW Stock DW Kimmel CB Zebrafish fgf24 functions with fgf8 to promote posterior mesodermal development Development 2003, 130:4639-4654. 12925590
9. Tanaka A Miyamoto K Minamino N Takeda M Sato B Matsuo H Matsumoto K Cloning and characterization of an androgen-induced growth factor essential for the androgen-dependent growth of mouse mammary carcinoma cells Proc Natl Acad Sci USA 1992, 89:8928-8932. 50037 1409588
10. MacArthur CA Lawshe A Xu J Santos-Ocampo S Heikinheimo M Chellaiah AT Ornitz DM FGF-8 isoforms activate receptor splice forms that are expressed in mesenchymal regions of mouse development Development 1995, 121:3603-3613. 8582274
11. Gemel J Gorry M Ehrlich GD MacArthur CA Structure and sequence of human FGF8 Genomics 1996, 35:253-257. 8661131
12. MacArthur CA Lawshe A Shankar DB Heikinheimo M Shackleford GM FGF-8 isoforms differ in NIH3T3 cell transforming potential Cell Growth Differ 1995, 6:817-825. 7547503
13. McKeehan WL Wang F Kan M The heparan sulfate-fibroblast growth factor family: Diversity of structure and function Prog Nucleic Acid Res Mol Biol. 1998, 59:135-176. 9427842
14. Ornitz DM Xu J Colvin JS McEwen DG MacArthur CA Coulier F Gao G Goldfarb M Receptor specificity of the fibroblast growth factor family J Biol Chem 1996, 271:15292-15297. 8663044
15. Blunt AG Lawshe A Cunningham ML Seto ML Ornitz DM MacArthur CA Overlapping expression and redundant activation of mesenchymal fibroblast growth factor (FGF) receptors by alternatively spliced FGF-8 ligands J Biol Chem 1997, 272:3733-3738. 9013630
16. Ohuchi H Yoshioka H Tanaka A Kawakami Y Nohno T Noji S Involvement of androgen-induced growth factor (FGF-8) gene in mouse embryogenesis and morphogenesis Biochem Biophys Res Commun 1994, 204:882-888. 7980556
17. Mahmood R Bresnick J Hornbruch A Mahony C Morton N Colquhoun K Martin P Lumsden A Dickson C Mason I A role for FGF-8 in the initiation and maintenance of vertebrate limb bud outgrowth Curr Biol 1995, 5:797-806. 7583127
18. Crossley PH Minowada G MacArthur CA Martin GR Roles for FGF8 in the induction, initiation, and maintenance of chick limb development Cell 1996, 84:127-136. 8548816
19. Sun X Mariani FV Martin GR Functions of FGF signalling from the apical ectodermal ridge in limb development Nature 2002, 418:501-508. 12152071
20. Valta MP Hentunen T Qu Q Valve EM Harjula A Seppanen JA Vaananen HK Harkonen PL Regulation of osteoblast differentiation: A novel function for fibroblast growth factor 8 Endocrinology 2006, 147:2171-2182. 16439448
21. Ishibe T Nakayama T Okamoto T Aoyama T Nishijo K Shibata KR Shima Y Nagayama S Katagiri T Nakamura Y Nakamura T Toguchida J Disruption of fibroblast growth factor signal pathway inhibits the growth of synovial sarcomas: Potential application of signal inhibitors to molecular target therapy Clin Cancer Res 2005, 11:2702-2712. 15814652
22. Kikuchi T Yamada H Shinmei M Effect of high molecular weight hyaluronan on cartilage degeneration in a rabbit model of osteoarthritis Osteoarthr Cartil 1996, 4:99-110. 8806112
23. Colombo C Butler M O' Byrne E Hickman L Swartzendruber D Selwyn M Steinetz B A new model of osteoarthritis in rabbits. I. Development of knee joint pathology following lateral meniscectomy and section of the fibular collateral and sesamoid ligaments Arthritis Rheum 1983, 26:875-886. 6688183
24. Tanaka A Furuya A Yamasaki M Hanai N Kuriki K Kamiakito T Kobayashi Y Yoshida H Koike M Fukayama M High frequency of fibroblast growth factor (FGF) 8 expression in clinical prostate cancers and breast tissues, immunohistochemically demonstrated by a newly established neutralizing antibody against FGF 8 Cancer Res 1998, 58:2053-2056. 9605740
25. Shimada N Ishii T Imada T Takaba K Sasaki Y Maruyama-Takahashi K Maekawa-Tokuda Y Kusaka H Akinaga S Tanaka A Shitara K A neutralizing anti-fibroblast growth factor 8 monoclonal antibody shows potent antitumor activity against androgen-dependent mouse mammary tumors in vivo Clin Cancer Res 2005, 15:3897-3904. 15897591
26. Janusz MJ Hookfin EB Heitmeyer SA Woessner JF Freemont AJ Hoyland JA Brown KK Hsieh LC Almstead NG De B Natchus MG Pikul S Taiwo YO Moderation of iodoacetate-induced experimental osteoarthritis in rats by matrix metalloproteinase inhibitors Osteoarthr Cartil 2001, 9:751-760. 11795995
27. Kuroki H Nakagawa Y Mori K Ohba M Suzuki T Mizuno Y Ando K Takenaka M Ikeuchi K Nakamura T Acoustic stiffness and change in plug cartilage over time after autologous osteochondral grafting: Correlation between ultrasound signal intensity and histological score in a rabbit model Arthritis Res Ther 2004, 6:R492-R504. 1064862 15535827
28. Tamura T Kosaka N Ishiwa J Sato T Nagase H Ito A Rhein, an active metabolite of diacerein, down-regulates the production of pro-matrix metalloproteinases-1, -3, -9 and -13 and up-regulates the production of tissue inhibitor of metalloproteinase-1 in cultured rabbit articular chondrocytes Osteoarthr Cartil 2001, 9:257-263. 11300749
29. Hamilton JA Slywka J Stimulation of human synovial fibroblast plasminogen activator production by mononuclear cell supernatants J Immunol 1981, 126:851-855. 6161965
30. Chandrasekhar S Esterman MA Hoffman NA Microdetermination of proteoglycan and glycosaminoglycans in the presence of guanidine hydrochloride Anal Biochem 1987, 161:103-108. 3578776
31. Yamada A Uegaki A Makamura T Ogawa K ONO - an orally active matrix metalloproteinase inhibitor, prevents lipopolysaccharide-induced proteoglycan release from the joint cartilage in guinea pigs Inflamm Res 2000, 49:144-146. 10858013
32. Schrier DJ Flory CM Finkel M Kuchera SL Lesch ME Jacobson PB The effects of the phospholipase A2 inhibitor, manoalide, on cartilage degradation, stromelysin expression, and synovial fluid cell count induced by intraarticular injection of human recombinant interleukin-1 in the rabbit Arthritis Rheum 1996, 39:1292-1299. 8702436
33. Tamura T Nakanishi T Kimura Y Hattori T Sasaki K Norimatsu H Takahashi K Takigawa M Nitric oxide mediates interleukin-1-induced matrix degradation and basic fibroblast growth factor release in cultured rabbit articular chondrocytes: A possible mechanism of pathological neovascularization in arthritis Endocrinology 1996, 137:3729-3737. 8756539
34. Evans CH Georgescu HI Observations on the senescence of cells derived from articular cartilage Mech Ageing Dev 1983, 22:179-191. 6632992
35. Stove J Gerlach C Huch K Gunther KP Brenner R Puhl W Scharf HP Gene expression of stromelysin and aggrecan in osteoarthritic cartilage Pathobiology 2001, 69:333-338. 12324711
36. Ayral X Pickering EH Woodworth TG Mackillop N Dougados M Synovitis a potential predictive factor of structural progression of medial tibiofemoral knee osteoarthritis - results of a 1 year longitudinal arthroscopic study in 422 patients Osteoarthritis Cartilage 2005, 13:361-367. 15882559
37. Arner EC Pratta MA Independent effects of interleukin-1 on proteoglycan breakdown, proteoglycan synthesis, and prostaglandin E2 release from cartilage in organ culture Arthritis Rheum 1989, 32:288-297. 2784682
38. Amin AR Attur M Patel RN Thakker GD Marshall PJ Rediske J Stuchin AS Patel IR Abramson SB Superinduction of cyclooxygenase-2 activity in human osteoarthritis-affected cartilage: Influence of nitric oxide J Clin Invest 1997, 99:1231-1237. 507937 9077531
39. Daouti S Latario B Nagulapalli S Buxton F Uziel-Fusi S Chirn GW Bodian D Song C Labow M Lotz M Quintavalla J Kumar C Development of comprehensive functional genomic screens to identify novel mediators of osteoarthritis Osteoarthr Cartil 2005, 13:508-518. 15922185
40. Chuma H Mizuta H Kudo S Takagi K Hiraki Y One day exposure to FGF-2 was sufficient for the regenerative repair of full-thickness defects of articular cartilage in rabbits Osteoarthr Cartil 2004, 12:834-842. 15450534
41. Kalbhen DA Blum U Hypothesis and experimental confirmation of a new pharmacological model of osteoarthrosis Arzneimittelforschung. 1977, 27:527-531. 141288