A neutralizing anti-fibroblast growth factor 8 monoclonal antibody shows potent antitumor activity against androgen-dependent mouse mammary tumors in vivo

Clinical Cancer Research

Volumn 11, Issue 10, 2005, Pages 3897-3904

  Shimada, Naoki ^a   Ishii, Toshihiko ^a   Imada, Teruyoshi ^a   Takaba, Katsumi ^a   Sasaki, Yuka ^a   Maruyama Takahashi, Kumiko ^a   Maekawa Tokuda, Yoshimi ^a   Kusaka, Hideaki ^a   Akinaga, Shiro ^a   Tanaka, Akira ^b   Shitara, Kenya ^a  

^a KYOWA HAKKO KOGYO CO LTD   (Japan)

^b JICHI MEDICAL UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ANDROGEN; FIBROBLAST GROWTH FACTOR 8; FIBROBLAST GROWTH FACTOR RECEPTOR 2; FIBROBLAST GROWTH FACTOR RECEPTOR 3; FIBROBLAST GROWTH FACTOR RECEPTOR 4; KM 1334; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MONOCLONAL ANTIBODY; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; BINDING AFFINITY; BREAST TUMOR; CELL SURVIVAL; CONTROLLED STUDY; DNA SYNTHESIS INHIBITION; DRUG EFFECT; DRUG POTENCY; DRUG PROTEIN BINDING; DRUG SPECIFICITY; ENZYME PHOSPHORYLATION; IN VITRO STUDY; IN VIVO STUDY; MALE; MOUSE; NICK END LABELING; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; TUMOR GROWTH; TUMOR REGRESSION;

ANIMALS; ANTIBODIES, MONOCLONAL; ANTIBODY SPECIFICITY; CELL PROLIFERATION; DNA; FIBROBLAST GROWTH FACTOR 8; FIBROBLAST GROWTH FACTORS; HUMANS; IMMUNOHISTOCHEMISTRY; MAMMARY NEOPLASMS, ANIMAL; MICE; MICE, NUDE; PROTEIN ISOFORMS; SIGNAL TRANSDUCTION; TUMOR CELLS, CULTURED;

EID: 21044433871     PISSN: 10780432     EISSN: None     Source Type: Journal    
DOI: 10.1158/1078-0432.CCR-04-2358     Document Type: Article

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