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Volumn 466, Issue 9, 2008, Pages 2046-2051

Polymorphisms and methylation of the reduced folate carrier in osteosarcoma

Author keywords

[No Author keywords available]

Indexed keywords

MESSENGER RNA; REDUCED FOLATE CARRIER; CARRIER PROTEIN; FOLIC ACID;

EID: 50649123781     PISSN: 0009921X     EISSN: 15281132     Source Type: Journal    
DOI: 10.1007/s11999-008-0323-3     Document Type: Conference Paper
Times cited : (18)

References (30)
  • 2
    • 0036144048 scopus 로고    scopus 로고
    • DNA methylation patterns and epigenetic memory
    • A Bird 2002 DNA methylation patterns and epigenetic memory Genes Dev 16 6 21
    • (2002) Genes Dev , vol.16 , pp. 6-21
    • Bird, A.1
  • 3
    • 0031803072 scopus 로고    scopus 로고
    • Post-transcriptional gene regulatory mechanisms in eukaryotes: An overview
    • DA Day MF Tuite 1998 Post-transcriptional gene regulatory mechanisms in eukaryotes: an overview J Endocrinol 157 361 371
    • (1998) J Endocrinol , vol.157 , pp. 361-371
    • Day, D.A.1    Tuite, M.F.2
  • 5
    • 0032807628 scopus 로고    scopus 로고
    • Isolation and characterization of genomic sequences involved in the regulation of the human reduced folate carrier gene (RFC1)
    • M Gong KH Cowan J Gudas JA Moscow 1999 Isolation and characterization of genomic sequences involved in the regulation of the human reduced folate carrier gene (RFC1) Gene 233 21 31
    • (1999) Gene , vol.233 , pp. 21-31
    • Gong, M.1    Cowan, K.H.2    Gudas, J.3    Moscow, J.A.4
  • 7
    • 0034771885 scopus 로고    scopus 로고
    • A novel single-nucleotide polymorphism in the 3′-untranslated region of the human dihydrofolate reductase gene with enhanced expression
    • Y Goto L Yue A Yokoi R Nishimura T Uehara S Koizumi Y Saikawa 2001 A novel single-nucleotide polymorphism in the 3′-untranslated region of the human dihydrofolate reductase gene with enhanced expression Clin Cancer Res 7 1952 1956
    • (2001) Clin Cancer Res , vol.7 , pp. 1952-1956
    • Goto, Y.1    Yue, L.2    Yokoi, A.3    Nishimura, R.4    Uehara, T.5    Koizumi, S.6    Saikawa, Y.7
  • 9
    • 0036274359 scopus 로고    scopus 로고
    • The fundamental role of epigenetic events in cancer
    • PA Jones SB Baylin 2002 The fundamental role of epigenetic events in cancer Nat Rev Genet 3 415 428
    • (2002) Nat Rev Genet , vol.3 , pp. 415-428
    • Jones, P.A.1    Baylin, S.B.2
  • 11
    • 0041305877 scopus 로고    scopus 로고
    • Membrane transport of folates
    • LH Matherly DI Goldman 2003 Membrane transport of folates Vitam Horm 66 403 456
    • (2003) Vitam Horm , vol.66 , pp. 403-456
    • Matherly, L.H.1    Goldman, D.I.2
  • 13
    • 0031861214 scopus 로고    scopus 로고
    • Intensification of preoperative chemotherapy for osteogenic sarcoma: Results of the Memorial Sloan-Kettering (T12) protocol
    • PA Meyers R Gorlick G Heller E Casper J Lane AG Huvos JH Healey 1998 Intensification of preoperative chemotherapy for osteogenic sarcoma: results of the Memorial Sloan-Kettering (T12) protocol J Clin Oncol 16 2452 2458
    • (1998) J Clin Oncol , vol.16 , pp. 2452-2458
    • Meyers, P.A.1    Gorlick, R.2    Heller, G.3    Casper, E.4    Lane, J.5    Huvos, A.G.6    Healey, J.H.7
  • 15
    • 0029147794 scopus 로고
    • Isolation of a gene encoding a human reduced folate carrier (RFC1) and analysis of its expression in transport-deficient, methotrexate-resistant human breast cancer cells
    • JA Moscow M Gong R He MK Sgagias KH Dixon SL Anzick PS Meltzer KH Cowan 1995 Isolation of a gene encoding a human reduced folate carrier (RFC1) and analysis of its expression in transport-deficient, methotrexate-resistant human breast cancer cells Cancer Res 55 3790 3794
    • (1995) Cancer Res , vol.55 , pp. 3790-3794
    • Moscow, J.A.1    Gong, M.2    He, R.3    Sgagias, M.K.4    Dixon, K.H.5    Anzick, S.L.6    Meltzer, P.S.7    Cowan, K.H.8
  • 16
    • 0033049593 scopus 로고    scopus 로고
    • Single-strand conformation polymorphism and heteroduplex analysis for gel-based mutation detection
    • AJ Nataraj I Olivos-Glander N Kusukawa WE Highsmith Jr 1999 Single-strand conformation polymorphism and heteroduplex analysis for gel-based mutation detection Electrophoresis 20 1177 1185
    • (1999) Electrophoresis , vol.20 , pp. 1177-1185
    • Nataraj, A.J.1    Olivos-Glander, I.2    Kusukawa, N.3    Highsmith Jr., W.E.4
  • 18
    • 1542754612 scopus 로고    scopus 로고
    • MRNA expression levels of E2F transcription factors correlate with dihydrofolate reductase, reduced folate carrier, and thymidylate synthase mRNA expression in osteosarcoma
    • R Sowers J Toguchida J Qin PA Meyers JH Healey A Huvos D Banerjee JR Bertino R Gorlick 2003 mRNA expression levels of E2F transcription factors correlate with dihydrofolate reductase, reduced folate carrier, and thymidylate synthase mRNA expression in osteosarcoma Mol Cancer Ther 2 535 541
    • (2003) Mol Cancer Ther , vol.2 , pp. 535-541
    • Sowers, R.1    Toguchida, J.2    Qin, J.3    Meyers, P.A.4    Healey, J.H.5    Huvos, A.6    Banerjee, D.7    Bertino, J.R.8    Gorlick, R.9
  • 19
    • 0039311993 scopus 로고    scopus 로고
    • Structural analysis of the human RFC-1 gene encoding a folate transporter reveals multiple promoters and alternatively spliced transcripts with 5′ end heterogeneity
    • B Tolner K Roy FM Sirotnak 1998 Structural analysis of the human RFC-1 gene encoding a folate transporter reveals multiple promoters and alternatively spliced transcripts with 5′ end heterogeneity Gene 211 331 341
    • (1998) Gene , vol.211 , pp. 331-341
    • Tolner, B.1    Roy, K.2    Sirotnak, F.M.3
  • 21
    • 0036846897 scopus 로고    scopus 로고
    • The human reduced folate carrier gene is ubiquitously and differentially expressed in normal human tissues: Identification of seven non-coding exons and characterization of a novel promoter
    • JR Whetstine RM Flatley LH Matherly 2002 The human reduced folate carrier gene is ubiquitously and differentially expressed in normal human tissues: identification of seven non-coding exons and characterization of a novel promoter Biochem J 367 629 640
    • (2002) Biochem J , vol.367 , pp. 629-640
    • Whetstine, J.R.1    Flatley, R.M.2    Matherly, L.H.3
  • 22
    • 0035794180 scopus 로고    scopus 로고
    • The basal promoters for the human reduced folate carrier gene are regulated by a GC-box and a cAMP-response element/AP-1-like element. Basis for tissue-specific gene expression
    • JR Whetstine LH Matherly 2001 The basal promoters for the human reduced folate carrier gene are regulated by a GC-box and a cAMP-response element/AP-1-like element. Basis for tissue-specific gene expression J Biol Chem 276 6350 6358
    • (2001) J Biol Chem , vol.276 , pp. 6350-6358
    • Whetstine, J.R.1    Matherly, L.H.2
  • 23
    • 0028887425 scopus 로고
    • Isolation of a human cDNA that complements a mutant hamster cell defective in methotrexate uptake
    • FM Williams WF Flintoff 1995 Isolation of a human cDNA that complements a mutant hamster cell defective in methotrexate uptake J Biol Chem 270 2987 2992
    • (1995) J Biol Chem , vol.270 , pp. 2987-2992
    • Williams, F.M.1    Flintoff, W.F.2
  • 24
    • 0032434114 scopus 로고    scopus 로고
    • Structural organization of the human reduced folate carrier gene: Evidence for 5′ heterogeneity in lymphoblast mRNA
    • FM Williams WF Flintoff 1998 Structural organization of the human reduced folate carrier gene: evidence for 5′ heterogeneity in lymphoblast mRNA Somat Cell Mol Genet 24 143 156
    • (1998) Somat Cell Mol Genet , vol.24 , pp. 143-156
    • Williams, F.M.1    Flintoff, W.F.2
  • 25
    • 0029084385 scopus 로고
    • Isolation of human cDNAs that restore methotrexate sensitivity and reduced folate carrier activity in methotrexate transport-defective Chinese hamster ovary cells
    • SC Wong SA Proefke A Bhushan LH Matherly 1995 Isolation of human cDNAs that restore methotrexate sensitivity and reduced folate carrier activity in methotrexate transport-defective Chinese hamster ovary cells J Biol Chem 270 17468 17475
    • (1995) J Biol Chem , vol.270 , pp. 17468-17475
    • Wong, S.C.1    Proefke, S.A.2    Bhushan, A.3    Matherly, L.H.4
  • 26
    • 0035955602 scopus 로고    scopus 로고
    • Methylation-dependent silencing of the reduced folate carrier gene in inherently methotrexate-resistant human breast cancer cells
    • J Worm AF Kirkin KN Dzhandzhugazyan P Guldberg 2001 Methylation-dependent silencing of the reduced folate carrier gene in inherently methotrexate- resistant human breast cancer cells J Biol Chem 276 39990 40000
    • (2001) J Biol Chem , vol.276 , pp. 39990-40000
    • Worm, J.1    Kirkin, A.F.2    Dzhandzhugazyan, K.N.3    Guldberg, P.4
  • 27
    • 34249089967 scopus 로고    scopus 로고
    • The folate receptor alpha is frequently overexpressed in osteosarcoma samples and plays a role in the uptake of the physiologic substrate 5-methyltetrahydrofolate
    • R Yang EA Kolb J Qin A Chou R Sowers B Hoang JH Healey AG Huvos PA Meyers R Gorlick 2007 The folate receptor alpha is frequently overexpressed in osteosarcoma samples and plays a role in the uptake of the physiologic substrate 5-methyltetrahydrofolate Clin Cancer Res 13 2557 2567
    • (2007) Clin Cancer Res , vol.13 , pp. 2557-2567
    • Yang, R.1    Kolb, E.A.2    Qin, J.3    Chou, A.4    Sowers, R.5    Hoang, B.6    Healey, J.H.7    Huvos, A.G.8    Meyers, P.A.9    Gorlick, R.10
  • 29
    • 0032525856 scopus 로고    scopus 로고
    • Transcript heterogeneity of the human reduced folate carrier results from the use of multiple promoters and variable splicing of alternative upstream exons
    • L Zhang SC Wong LH Matherly 1998 Transcript heterogeneity of the human reduced folate carrier results from the use of multiple promoters and variable splicing of alternative upstream exons Biochem J 332 773 780
    • (1998) Biochem J , vol.332 , pp. 773-780
    • Zhang, L.1    Wong, S.C.2    Matherly, L.H.3
  • 30
    • 0344393780 scopus 로고    scopus 로고
    • Resistance to antifolates
    • R Zhao ID Goldman 2003 Resistance to antifolates Oncogene 22 7431 7457
    • (2003) Oncogene , vol.22 , pp. 7431-7457
    • Zhao, R.1    Goldman, I.D.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.