Adverse effects of obesity on β-cell function in Japanese subjects with normal glucose tolerance

Obesity Research and Clinical Practice

Volumn 2, Issue 3, 2008, Pages 195-202

  Akehi, Yuko ^a   Anzai, Keizo ^a   Katsuta, Hitoshi ^a   Yoshida, Ryoko ^a   Ohkubo, Kumiko ^a   Yamashita, Takaaki ^a   Kawashima, Hironobu ^a   Ono, Junko ^a  

^a FUKUOKA UNIVERSITY   (Japan)

Author keywords

Cell function; Insulin sensitivity; Normal glucose tolerance; Obesity; Oral glucose tolerance test

Indexed keywords

GLUCOSE; INSULIN;

ADULT; ARTICLE; CONTROLLED STUDY; DIET RESTRICTION; FEMALE; GLUCOSE BLOOD LEVEL; GLUCOSE TOLERANCE; HOMEOSTASIS; HUMAN; IMPAIRED GLUCOSE TOLERANCE; INSULIN RELEASE; INSULIN RESISTANCE; INSULIN SENSITIVITY; JAPANESE; MAJOR CLINICAL STUDY; MALE; OBESITY; ORAL GLUCOSE TOLERANCE TEST; PANCREAS ISLET CELL FUNCTION; PRIORITY JOURNAL;

EID: 50649117101     PISSN: 1871403X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.orcp.2008.05.002     Document Type: Article

References (23)

1. Kahn S.E., Prigeon R.L., McCulloch D.K., Boyko E.D., Bergman R.N., Schwartz M.W., et al. Quantification of the relationship between insulin sensitivity and β-cell function in human subjects. Diabetes 42 (1993) 1663-1672
2. Polonsky K.S., Sturis J., and Bell G. Non-insulin-dependent diabetes mellitus: a genetically programmed failure of the beta cell to compensate for insulin resistance. N Engl J Med 334 (1996) 777-783
3. Weyer C., Bogardus C., Mott D.M., and Pratley R.E. The natural history of insulin secretory dysfunction and insulin resistance in the pathogenesis of type 2 diabetes mellitus. J Clin Invest 104 (1999) 787-794
4. Kahn S.E. Clinical review 135. The importance of β-cell failure in the development and progression of type 2 diabetes. J Clin Endocrinol Metab 86 (2001) 4047-4058
5. Gastaldelli A., Ferrannini E., Miyazaki Y., Matsuda M., and DeFronzo R.A. Beta-cell dysfunction and glucose intolerance: results from the San Antonio metabolism (SAM) study. Diabetologia 47 (2004) 31-39
6. Festa A., Williams K., D'Agostino Jr. R., Wagenknecht L.E., and Haffner S.M. The natural course of β-cell function in nondiabetic and diabetic individuals: the insulin resistance atherosclerosis study. Diabetes 55 (2006) 1114-1120
7. Bergman R.N., Phillips L.S., and Cobelli C. Physiologic evaluation of factors controlling glucose tolerance in man: measurement of insulin sensitivity and beta-cell glucose sensitivity from the response to intravenous glucose. J Clin Invest 68 (1981) 1456-1467
8. Bergman R.N. Toward physiological understanding of glucose tolerance: minimal model approach. Diabetes 38 (1989) 1512-1527
9. Reaven G.M. Role of insulin resistance in human disease. Diabetes 37 (1988) 1595-1607
10. Kolterman O.G., Insel J., Saekow M., and Olefsky J.M. Mechanisms of insulin resistance in human obesity: evidence for receptor and postreceptor defects. J Clin Invest 65 (1980) 1272-1284
11. Kuroe A., Fukushima M., Usami M., Ikeda M., Nakai Y., Taniguchi A., et al. Impaired β-cell function and insulin sensitivity in Japanese subjects with normal glucose tolerance. Diabetes Res Clin Pract 59 (2003) 71-77
12. Jensen C.C., Cnop M., Hull R.L., Fujimoto W.Y., Kahn S.E., and American Diabetes Association GENNID Study Group. β-Cell function is a major contributor of oral glucose tolerance in high-risk relatives of four ethnic groups in the U.S. Diabetes 51 (2002) 2170-2178
13. Alberti K.G., and Zimmet P.Z. Definition, diagnosis and classification of diabetes mellitus and its complications. Part 1: diagnosis and classification of diabetes mellitus provisional report of a WHO consultation. Diabet Med 15 (1998) 539-553
14. Matthews D.R., Hosker J.P., Rudenski A.S., Naylor B.A., Treacher D.F., and Turner R.C. Homeostasis model assessment: insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man. Diabetologia 28 (1985) 412-419
15. Abdul-Ghani M.A., Jenkinson C.P., Richardson D.K., Tripathy D., and DeFronzo R.A. Insulin secretion and action in subjects with impaired fasting glucose and impaired glucose tolerance: result from the veterans administration genetic epidemiology study. Diabetes 55 (2006) 1430-1435
16. Basu R., Breda E., Oberg A.L., Powell C.C., Man C.D., Basu A., et al. Mechanisms of the age-associated deterioration in glucose tolerance. Diabetes 52 (2003) 1738-1748
17. Matsuda M., and DeFronzo R.A. Insulin sensitivity indices obtained from oral glucose tolerance testing: comparison with the euglycemic glucose clamp. Diabetes Care 22 (1999) 1462-1470
18. Chang A.M., and Halter J.B. Aging and insulin secretion. Am J Physiol Endocrinol Metab 284 (2002) E7-E12
19. Chen M., Bergman R.N., Pacini G., and Porte Jr. D. Pathogenesis of age-related glucose intolerance in man: insulin resistance and decreased β-cell function. J Clin Endocrinol Metab 60 (1985) 13-20
20. Fritsche A., Madaus A., Stefan N., Tschritter O., Maerker E., Teigeler A., et al. Relationships among age, proinsulin conversion, and β-cell function in nondiabetic humans. Diabetes 51 (2002) S234-S239
21. Mbanya J.C., Pani L.N., Mbanya D.N., Sobngwi E., and Ngogang J. Reduced insulin secretion in offspring of African type 2 diabetic parents. Diabetes Care 23 (2000) 1761-1765
22. Ryder E., Gómez M.E., Fernández V., Campos G., Morales L.M., Valbuena H., et al. Presence of impaired insulin secretion and insulin resistance in normoglycemic male subjects with family history of type 2 diabetes. Diabetes Res Clin Pract 60 (2003) 95-103
23. Kang E.S., Yun Y.S., Park S.W., Kim H.J., Ahn C.W., Song Y.D., et al. Limitation of the validity of the homeostasis model assessment as an index of insulin resistance in Korea. Metabolism 54 (2005) 206-211