Study on Synthesis and Chloramphenicol Release of Poly(2-hydroxyethylmethacrylate-co-acrylamide) Hydrogels

Chinese Journal of Chemical Engineering

Volumn 16, Issue 4, 2008, Pages 640-645

  LI, Xinming ^a   CUI, Yingde ^a  

^a ZHONGKAI UNIVERSITY OF AGRICULTURE AND ENGINEERING   (China)

Author keywords

chloramphenicol; drug delivery; hydrogels; pH sensible

Indexed keywords

ABS RESINS; ACRYLIC MONOMERS; AMIDES; ANTIBIOTICS; BIOLOGICAL MATERIALS; COMPUTER NETWORKS; CONTACT LENSES; COPOLYMERIZATION; DRUG DELIVERY; MARKOV PROCESSES; ORGANIC POLYMERS; PHOTORESISTS; POLYMERS; WATER CONTENT;

2-HYDROXYETHYL METHACRYLATES; CHLORAMPHENICOL; PH-SENSIBLE;

HYDROGELS;

EID: 50549102072     PISSN: 10049541     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1004-9541(08)60134-2     Document Type: Article

References (31)

1. Bourlais C.L., Acar L., Zia H., Sado P.A., Needham T., and Leverge R. "Ophthalmic drug delivery systems". Prog. Retinal Eye Res. 17 (1998) 33-58
2. Creech J.L., Chauhan A., and Radke C.J. "Dispersive mixing in the posterior tear film under a soft contact lens". I&EC Res. 40 (1999) 3015-3026
3. Mc Namara N.A., Polse K.A., Brand R.D., Graham A.D., Chan J.S., and McKenney C.D. "Tear mixing under a soft contact lens: Effects of lens diameter". Am. J. Ophthal. 127 (1999) 659-665
4. Wilson C.G. "Topical drug delivery in the eye". Exp. Eye Res. 78 (2004) 737-743
5. Hughes P.M., Olejnik O., Chang-Lin J.E., and Wilson C.G. "Topical and systemic drug delivery to the posterior segments". Adv. Drug Del. Rev. 57 (2005) 2010-2032
6. Lang J.C. "Ocular drug delivery conventional ocular formulations". Adv. Drug Delivery. 16 (1995) 39-43
7. Deshpande S.G., and Shirolkar S. "Sustained release ophthalmic formulations of pilocarpine". J. Pharm. Pharmacol. 41 (1989) 197-200
8. Ding S. "Recent developments in ophthalmic drug delivery". Pharm. Sci. Technol. Today. 1 (1998) 328-335
9. Lin H.R., and Sung K.C. "Carbopol/pluronic phase change solutions for ophthalmic drug delivery". J. Controlled Rel. 69 (2000) 379-388
10. Gulsen D., Li C.C., and Chauhan A. "Dispersion of DMPC liposomes in contact lenses for ophthalmic drug delivery". Current Eye Research 30 12 (2000) 1071-1080
11. Gulsen D., and Chauhan A. "Ophthalmic drug delivery through contact lenses". Investig. Ophthal. Vis. Sci. 45 7 (2004) 2342-2347
12. Alvarez-Lorenzo C., Hiratani H., and Concheiro A. "Contact lenses for drug delivery: Achieving sustained release with novel systems". Am. J. Drug Deliv. 4 3 (2006) 131-151
13. Warlen M., Matoba A., Robinson N., and Gay C. "Ocular delivery of tobramycin with a disposable soft contact lens". Investig. Ophthal. Vis. Sci. 33 4 (1992) 938
14. Andrade-Vivero P., Fernandez-Gabriel E., Alvarez-Lorenzo C., and Concheiro A. "Improving the loading and release of NSAIDs from pHEMA hydrogels by copolymerization with functionalized monomers". J. Pharm. Sci. 96 4 (2007) 802-813
15. Garcia D.M., Escobar J.L., Noa Y., Bada N., Hernaez E., and Katime I. "Timolol maleate release from pH-sensible poly (2-hydroxyethyl methacrylate-co-methacrylic acid) hydrogels". Eur. Polymer J. 40 (2004) 1683-1690
16. Karlgard C.C.S., Wong N.S., Jones L.W., and Moresoli C. "In vitro uptake and release studies of ocular pharmaceutical agents by silicon-containing and p-HEMA hydrogel contact lens materials". Int. J. Pharm. 257 (2003) 141-151
17. Winterton L.C., Lally J.M., Sentell K.B., and Chapoy L.L. "The elution of poly (vinyl alcohol) from a contact lens: The realization of a time release moisturizing agent/artificial tear". J. Biomed. Mater. Res. B-Appl. Biomater. 80B 2 (2007) 424-432
18. Sano K., Tokoro T., and Imai Y. "A new drug delivery system utilizing piggyback contact lenses". Acta Ophthalmol 74 (1996) 243-248
19. Gulsen D., and Chauhan A. "Dispersion of microemulsion drops in HEMA hydrogel: A potential ophthalmic drug delivery vehicle". Int. J. Pharm. 292 (2005) 95-117
20. Uchida R., Sato T., Tanigawa H., and Uno K. "Azulene incorporation and release by hydrogel containing methacrylamide propyltrimethylammonium chloride, and its application to soft contact lens". J. Control. Release 92 (2003) 259-264
21. Sato T., Uchida R., Tanigawa H., Uno K., and Murakami A. "Application of polymer gels containing side-chain phosphate groups to drug-delivery contact lenses". J. Appl. Polym. Sci. 98 (2005) 731-735
22. Alvarez-Lorenzo C., Hiratani H., Gomez-Amoza J.L., Martinez-Pacheco R., Souto C., and Concheiro A. "Soft contact lenses capable of sustained delivery of timolol". J. Pharm. Sci. 91 10 (2002) 2182-2192
23. Alvarez-Lorenzo C., Yañez F., Barreiro-Iglesias R., and Concheiro A. "Imprinted soft contact lenses as norfloxacin delivery systems". J. Control. Release 113 (2006) 236-244
24. Hiratani H., and Alvarez-Lorenzo C. "Timolol uptake and release by imprinted soft contact lenses made of N,N-diethylacrylamide and methacrylic acid". J. Control. Release 83 (2002) 223-230
25. Hiratani H., and Alvarez-Lorenzo C. "The nature of backbone monomers determines the performance of imprinted soft contact lenses as timolol drug delivery systems". Biomaterials 25 (2004) 1105-1113
26. Hiratani H., Fujiwara A., Tamiya Y., Mizutani Y., and Alvarez-Lorenzo C. "Ocular release of timolol from molecularly imprinted soft contact lenses". Biomaterials 26 (2005) 1293-1298
27. Venkatesh S., Sizemore S.P., and Mark E.B. "Biomimetic hydrogels for enhanced loading and extended release of ocular therapeutics". Biomaterials 28 (2007) 717-724
28. Hiratani H., Mizutani Y., and Alvarez-Lorenzo C. "Controlling drug release from imprinted hydrogels by modifying the characteristics of the imprinted cavities". Macromol. Biosci. 5 (2005) 728-733
29. Li C.C., and Chauhan A. "Modeling ophthalmic drug delivery by soaked contact lenses". Ind. Eng. Chem. Res. 45 (2006) 3718-3734
30. Thygesen J.E., and Jensen O.L. "pH changes of the tear fluid in the conjunctival sac during postoperative inflammation of the human eye". Acta Ophthalmol (Copenh). 65 2 (1987) 134-136
31. Haroldo C.B.P., Regina C.M.P., and Sterlane K.F.B. "Swelling and release kinetics of larvicide-containing chitosan/cashew gum beads". J. Appl. Polym. Sci. 102 (2006) 395-400