메뉴 건너뛰기




Volumn 17, Issue 4, 2008, Pages 787-801

Developing Drugs for Core Social and Communication Impairment in Autism

Author keywords

[No Author keywords available]

Indexed keywords

AMANTADINE; ARIPIPRAZOLE; CHOLINERGIC RECEPTOR STIMULATING AGENT; CITALOPRAM; CYCLOSERINE; DEXTROMETHORPHAN; DONEPEZIL; ESCITALOPRAM; FENFLURAMINE; FLUOXETINE; FLUVOXAMINE; GALANTAMINE; GLUTAMATE RECEPTOR AGONIST; GLUTAMIC ACID; LAMOTRIGINE; MEMANTINE; NALTREXONE; OLANZAPINE; OXYTOCIN; PAROXETINE; PLACEBO; QUETIAPINE; RISPERIDONE; RIVASTIGMINE; SECRETIN; SEROTONIN UPTAKE INHIBITOR; SERTRALINE; TACRINE; ZIPRASIDONE;

EID: 50449092541     PISSN: 10564993     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.chc.2008.06.010     Document Type: Review
Times cited : (58)

References (69)
  • 1
    • 33749072404 scopus 로고    scopus 로고
    • Behavioral and emotional problems in young people with pervasive developmental disorders: relative prevalence, effects of subject characteristics, and empirical classification
    • Lecavalier L. Behavioral and emotional problems in young people with pervasive developmental disorders: relative prevalence, effects of subject characteristics, and empirical classification. J Autism Dev Disord 36 8 (2006) 1101-1114
    • (2006) J Autism Dev Disord , vol.36 , Issue.8 , pp. 1101-1114
    • Lecavalier, L.1
  • 2
    • 14944346244 scopus 로고    scopus 로고
    • Medication patterns in patients with autism: temporal, regional, and demographic influences
    • Aman M.G., Lam K.S., and Van Bourgondien M.E. Medication patterns in patients with autism: temporal, regional, and demographic influences. J Child Adolesc Psychopharmacol 15 1 (2005) 116-126
    • (2005) J Child Adolesc Psychopharmacol , vol.15 , Issue.1 , pp. 116-126
    • Aman, M.G.1    Lam, K.S.2    Van Bourgondien, M.E.3
  • 3
    • 0028906338 scopus 로고
    • Autism as a strongly genetic disorder: evidence from a British twin study
    • Bailey A., Le Couteur A., Gottesman I., et al. Autism as a strongly genetic disorder: evidence from a British twin study. Psychol Med 25 1 (1995) 63-77
    • (1995) Psychol Med , vol.25 , Issue.1 , pp. 63-77
    • Bailey, A.1    Le Couteur, A.2    Gottesman, I.3
  • 4
    • 21344460723 scopus 로고    scopus 로고
    • When is the brain enlarged in autism? A meta-analysis of all brain size reports
    • Redcay E., and Courchesne E. When is the brain enlarged in autism? A meta-analysis of all brain size reports. Biol Psychiatry 58 1 (2005) 1-9
    • (2005) Biol Psychiatry , vol.58 , Issue.1 , pp. 1-9
    • Redcay, E.1    Courchesne, E.2
  • 5
    • 50449091022 scopus 로고    scopus 로고
    • The social brain in autism: perspectives from neuropsychology and neuroimaging
    • Moldin S.O., and Rubenstein J.L.R. (Eds), CRC Press, Boca Raton (FL)
    • Schultz R.T., Chawarska K., and Volkmar F. The social brain in autism: perspectives from neuropsychology and neuroimaging. In: Moldin S.O., and Rubenstein J.L.R. (Eds). Understanding autism: from basic neuroscience to treatment (2006), CRC Press, Boca Raton (FL) 323-348
    • (2006) Understanding autism: from basic neuroscience to treatment , pp. 323-348
    • Schultz, R.T.1    Chawarska, K.2    Volkmar, F.3
  • 6
    • 0027997172 scopus 로고
    • Autism Diagnostic Interview-Revised: a revised version of a diagnostic interview for caregivers of individuals with possible pervasive developmental disorders
    • Lord C., Rutter M., and Le Couteur A. Autism Diagnostic Interview-Revised: a revised version of a diagnostic interview for caregivers of individuals with possible pervasive developmental disorders. J Autism Dev Disord 24 5 (1994) 659-685
    • (1994) J Autism Dev Disord , vol.24 , Issue.5 , pp. 659-685
    • Lord, C.1    Rutter, M.2    Le Couteur, A.3
  • 7
    • 0035958295 scopus 로고    scopus 로고
    • Pervasive developmental disorders in preschool children
    • Chakrabarti S., and Fombonne E. Pervasive developmental disorders in preschool children. JAMA 285 24 (2001) 3093-3099
    • (2001) JAMA , vol.285 , Issue.24 , pp. 3093-3099
    • Chakrabarti, S.1    Fombonne, E.2
  • 8
    • 0034101344 scopus 로고    scopus 로고
    • Research Units on Pediatric Psychopharmacology (RUPP) Autism Network. Background and rationale for an initial controlled study of risperidone
    • McDougle C.J., Scahill L., McCracken J.T., et al. Research Units on Pediatric Psychopharmacology (RUPP) Autism Network. Background and rationale for an initial controlled study of risperidone. Child Adolesc Psychiatr Clin N Am 9 1 (2000) 201-224
    • (2000) Child Adolesc Psychiatr Clin N Am , vol.9 , Issue.1 , pp. 201-224
    • McDougle, C.J.1    Scahill, L.2    McCracken, J.T.3
  • 9
    • 0030876952 scopus 로고    scopus 로고
    • Valvular heart disease associated with fenfluramine-phentermine
    • Connolly H.M., Crary J.L., McGoon M.D., et al. Valvular heart disease associated with fenfluramine-phentermine. N Engl J Med 337 9 (1997) 581-588
    • (1997) N Engl J Med , vol.337 , Issue.9 , pp. 581-588
    • Connolly, H.M.1    Crary, J.L.2    McGoon, M.D.3
  • 10
    • 0019987958 scopus 로고
    • Preliminary observations on the effect of fenfluramine on blood serotonin and symptoms in three autistic boys
    • Geller E., Ritvo E.R., Freeman B.J., et al. Preliminary observations on the effect of fenfluramine on blood serotonin and symptoms in three autistic boys. N Engl J Med 307 3 (1982) 165-169
    • (1982) N Engl J Med , vol.307 , Issue.3 , pp. 165-169
    • Geller, E.1    Ritvo, E.R.2    Freeman, B.J.3
  • 11
    • 0022569992 scopus 로고
    • Fenfluramine treatment of autism: UCLA collaborative study of 81 patients at nine medical centers
    • Ritvo E.R., Freeman B.J., Yuwiler A., et al. Fenfluramine treatment of autism: UCLA collaborative study of 81 patients at nine medical centers. Psychopharmacol Bull 22 1 (1986) 133-140
    • (1986) Psychopharmacol Bull , vol.22 , Issue.1 , pp. 133-140
    • Ritvo, E.R.1    Freeman, B.J.2    Yuwiler, A.3
  • 12
  • 13
    • 0023219002 scopus 로고
    • Brain opioids and autism: an updated analysis of possible linkages
    • Sahley T.L., and Panksepp J. Brain opioids and autism: an updated analysis of possible linkages. J Aut Dev Disorders 17 2 (1987) 201-216
    • (1987) J Aut Dev Disorders , vol.17 , Issue.2 , pp. 201-216
    • Sahley, T.L.1    Panksepp, J.2
  • 14
    • 0027440466 scopus 로고
    • Naltrexone in autistic children: behavioral symptoms and attentional learning
    • Campbell M., Anderson L.T., Small A.M., et al. Naltrexone in autistic children: behavioral symptoms and attentional learning. J Am Acad Child Adolesc Psychiatry 32 6 (1993) 1283-1291
    • (1993) J Am Acad Child Adolesc Psychiatry , vol.32 , Issue.6 , pp. 1283-1291
    • Campbell, M.1    Anderson, L.T.2    Small, A.M.3
  • 15
    • 0028788163 scopus 로고
    • Placebo-controlled acute dosage naltrexone study in young autistic children
    • Willemsen-Swinkels S.H., Buitelaar J.K., Weijnen F.G., et al. Placebo-controlled acute dosage naltrexone study in young autistic children. Psychiatry Res 58 3 (1995) 203-215
    • (1995) Psychiatry Res , vol.58 , Issue.3 , pp. 203-215
    • Willemsen-Swinkels, S.H.1    Buitelaar, J.K.2    Weijnen, F.G.3
  • 16
    • 0029074854 scopus 로고
    • Failure of naltrexone hydrochloride to reduce self-injurious and autistic behavior in mentally retarded adults. Double-blind placebo-controlled studies
    • Willemsen-Swinkels S.H., Buitelaar J.K., Nijhof G.J., et al. Failure of naltrexone hydrochloride to reduce self-injurious and autistic behavior in mentally retarded adults. Double-blind placebo-controlled studies. Arch Gen Psychiatry 52 9 (1995) 766-773
    • (1995) Arch Gen Psychiatry , vol.52 , Issue.9 , pp. 766-773
    • Willemsen-Swinkels, S.H.1    Buitelaar, J.K.2    Nijhof, G.J.3
  • 18
    • 0031631341 scopus 로고    scopus 로고
    • Improved social and language skills after secretin administration in patients with autistic spectrum disorders
    • Horvath K., Stefanatos G., Sokolski K.N., et al. Improved social and language skills after secretin administration in patients with autistic spectrum disorders. J Assoc Acad Minor Phys 9 1 (1998) 9-15
    • (1998) J Assoc Acad Minor Phys , vol.9 , Issue.1 , pp. 9-15
    • Horvath, K.1    Stefanatos, G.2    Sokolski, K.N.3
  • 19
    • 0029803880 scopus 로고    scopus 로고
    • A double-blind, placebo-controlled study of fluvoxamine in adults with autistic disorder
    • McDougle C.J., Naylor S.T., Cohen D.J., et al. A double-blind, placebo-controlled study of fluvoxamine in adults with autistic disorder. Arch Gen Psychiatry 53 11 (1996) 1001-1008
    • (1996) Arch Gen Psychiatry , vol.53 , Issue.11 , pp. 1001-1008
    • McDougle, C.J.1    Naylor, S.T.2    Cohen, D.J.3
  • 20
    • 0033746434 scopus 로고    scopus 로고
    • Repetitive thoughts and behavior in pervasive developmental disorders: treatment with serotonin reuptake inhibitors
    • McDougle C.J., Kresch L.E., and Posey D.J. Repetitive thoughts and behavior in pervasive developmental disorders: treatment with serotonin reuptake inhibitors. J Autism Dev Disord 30 5 (2000) 427-435
    • (2000) J Autism Dev Disord , vol.30 , Issue.5 , pp. 427-435
    • McDougle, C.J.1    Kresch, L.E.2    Posey, D.J.3
  • 21
    • 13944264748 scopus 로고    scopus 로고
    • A placebo controlled crossover trial of liquid fluoxetine on repetitive behaviors in childhood and adolescent autism
    • Hollander E., Phillips A., Chaplin W., et al. A placebo controlled crossover trial of liquid fluoxetine on repetitive behaviors in childhood and adolescent autism. Neuropsychopharmacology 30 3 (2005) 582-589
    • (2005) Neuropsychopharmacology , vol.30 , Issue.3 , pp. 582-589
    • Hollander, E.1    Phillips, A.2    Chaplin, W.3
  • 23
    • 33645825616 scopus 로고    scopus 로고
    • The use of selective serotonin reuptake inhibitors in autism and related disorders
    • Posey D.J., Erickson C.A., Stigler K.A., et al. The use of selective serotonin reuptake inhibitors in autism and related disorders. J Child Adolesc Psychopharmacol 16 1-2 (2006) 181-186
    • (2006) J Child Adolesc Psychopharmacol , vol.16 , Issue.1-2 , pp. 181-186
    • Posey, D.J.1    Erickson, C.A.2    Stigler, K.A.3
  • 24
    • 0036772795 scopus 로고    scopus 로고
    • Fluoxetine response in children with autistic spectrum disorders: correlation with familial major affective disorder and intellectual achievement
    • DeLong G.R., Ritch C.R., and Burch S. Fluoxetine response in children with autistic spectrum disorders: correlation with familial major affective disorder and intellectual achievement. Dev Med Child Neurol 44 10 (2002) 652-659
    • (2002) Dev Med Child Neurol , vol.44 , Issue.10 , pp. 652-659
    • DeLong, G.R.1    Ritch, C.R.2    Burch, S.3
  • 25
    • 0031855086 scopus 로고    scopus 로고
    • A double-blind, placebo-controlled study of risperidone in adults with autistic disorder and other pervasive developmental disorders
    • McDougle C.J., Holmes J.P., Carlson D.C., et al. A double-blind, placebo-controlled study of risperidone in adults with autistic disorder and other pervasive developmental disorders. Arch Gen Psychiatry 55 7 (1998) 633-641
    • (1998) Arch Gen Psychiatry , vol.55 , Issue.7 , pp. 633-641
    • McDougle, C.J.1    Holmes, J.P.2    Carlson, D.C.3
  • 27
    • 0022003626 scopus 로고
    • The aberrant behavior checklist: a behavior rating scale for the assessment of treatment effects
    • Aman M.G., Singh N.N., Stewart A.W., et al. The aberrant behavior checklist: a behavior rating scale for the assessment of treatment effects. Am J Ment Defic 5 (1985) 485-491
    • (1985) Am J Ment Defic , vol.5 , pp. 485-491
    • Aman, M.G.1    Singh, N.N.2    Stewart, A.W.3
  • 28
    • 20044374710 scopus 로고    scopus 로고
    • Risperidone for the core symptom domains of autism: results from the study by the autism network of the research units on pediatric psychopharmacology
    • McDougle C.J., Scahill L., Aman M.G., et al. Risperidone for the core symptom domains of autism: results from the study by the autism network of the research units on pediatric psychopharmacology. Am J Psychiatry 162 6 (2005) 1142-1148
    • (2005) Am J Psychiatry , vol.162 , Issue.6 , pp. 1142-1148
    • McDougle, C.J.1    Scahill, L.2    Aman, M.G.3
  • 29
    • 0022629169 scopus 로고
    • A scale for rating symptoms of patients with the syndrome of autism in real life settings
    • Freeman B.J., Ritvo E.R., Yokota A., et al. A scale for rating symptoms of patients with the syndrome of autism in real life settings. J Am Acad Child Psychiatry 25 1 (1986) 130-136
    • (1986) J Am Acad Child Psychiatry , vol.25 , Issue.1 , pp. 130-136
    • Freeman, B.J.1    Ritvo, E.R.2    Yokota, A.3
  • 30
    • 33748431414 scopus 로고    scopus 로고
    • Children's Yale-Brown Obsessive Compulsive Scale modified for pervasive developmental disorders
    • Scahill L., McDougle C.J., Williams S.K., et al. Children's Yale-Brown Obsessive Compulsive Scale modified for pervasive developmental disorders. J Am Acad Child Adolesc Psychiatry 45 9 (2006) 1114-1123
    • (2006) J Am Acad Child Adolesc Psychiatry , vol.45 , Issue.9 , pp. 1114-1123
    • Scahill, L.1    McDougle, C.J.2    Williams, S.K.3
  • 31
    • 16644370679 scopus 로고    scopus 로고
    • Risperidone in the treatment of disruptive behavioral symptoms in children with autistic and other pervasive developmental disorders
    • Shea S., Turgay A., Carroll A., et al. Risperidone in the treatment of disruptive behavioral symptoms in children with autistic and other pervasive developmental disorders. Pediatrics 114 5 (2004) e634-e641
    • (2004) Pediatrics , vol.114 , Issue.5
    • Shea, S.1    Turgay, A.2    Carroll, A.3
  • 32
    • 0033461141 scopus 로고    scopus 로고
    • Risperidone in the treatment of two very young children with autism
    • Posey D.J., Walsh K.H., Wilson G.A., et al. Risperidone in the treatment of two very young children with autism. J Child Adolesc Psychopharmacol 9 4 (1999) 273-276
    • (1999) J Child Adolesc Psychopharmacol , vol.9 , Issue.4 , pp. 273-276
    • Posey, D.J.1    Walsh, K.H.2    Wilson, G.A.3
  • 33
    • 33746053489 scopus 로고    scopus 로고
    • Risperidone in children with autism: randomized, placebo-controlled, double-blind study
    • Nagaraj R., Singhi P., and Malhi P. Risperidone in children with autism: randomized, placebo-controlled, double-blind study. J Child Neurol 21 6 (2006) 450-455
    • (2006) J Child Neurol , vol.21 , Issue.6 , pp. 450-455
    • Nagaraj, R.1    Singhi, P.2    Malhi, P.3
  • 34
    • 0018854085 scopus 로고
    • Toward objective classification of childhood autism: Childhood Autism Rating Scale (CARS)
    • Schopler E., Reichler R.J., DeVellis R.F., et al. Toward objective classification of childhood autism: Childhood Autism Rating Scale (CARS). J Autism Dev Disord 10 1 (1980) 91-103
    • (1980) J Autism Dev Disord , vol.10 , Issue.1 , pp. 91-103
    • Schopler, E.1    Reichler, R.J.2    DeVellis, R.F.3
  • 35
    • 33750939062 scopus 로고    scopus 로고
    • Risperidone in preschool children with autistic spectrum disorders: an investigation of safety and efficacy
    • Luby J., Mrakotsky C., Stalets M.M., et al. Risperidone in preschool children with autistic spectrum disorders: an investigation of safety and efficacy. J Child Adolesc Psychopharmacol 16 5 (2006) 575-587
    • (2006) J Child Adolesc Psychopharmacol , vol.16 , Issue.5 , pp. 575-587
    • Luby, J.1    Mrakotsky, C.2    Stalets, M.M.3
  • 36
    • 0033071543 scopus 로고    scopus 로고
    • Olanzapine treatment of children, adolescents, and adults with pervasive developmental disorders: an open-label pilot study
    • Potenza M.N., Holmes J.P., Kanes S.J., et al. Olanzapine treatment of children, adolescents, and adults with pervasive developmental disorders: an open-label pilot study. J Clin Psychopharmacol 19 1 (1999) 37-44
    • (1999) J Clin Psychopharmacol , vol.19 , Issue.1 , pp. 37-44
    • Potenza, M.N.1    Holmes, J.P.2    Kanes, S.J.3
  • 37
    • 0034918679 scopus 로고    scopus 로고
    • Olanzapine versus haloperidol in children with autistic disorder: an open pilot study
    • Malone R.P., Cater J., Sheikh R.M., et al. Olanzapine versus haloperidol in children with autistic disorder: an open pilot study. J Am Acad Child Adolesc Psychiatry 40 8 (2001) 887-894
    • (2001) J Am Acad Child Adolesc Psychiatry , vol.40 , Issue.8 , pp. 887-894
    • Malone, R.P.1    Cater, J.2    Sheikh, R.M.3
  • 38
    • 0036785079 scopus 로고    scopus 로고
    • Open-label study of olanzapine in children with pervasive developmental disorder
    • Kemner C., Willemsen-Swinkels S.H., de Jonge M., et al. Open-label study of olanzapine in children with pervasive developmental disorder. J Clin Psychopharmacol 22 5 (2002) 455-460
    • (2002) J Clin Psychopharmacol , vol.22 , Issue.5 , pp. 455-460
    • Kemner, C.1    Willemsen-Swinkels, S.H.2    de Jonge, M.3
  • 39
    • 33750952522 scopus 로고    scopus 로고
    • A double-blind placebo-controlled pilot study of olanzapine in childhood/adolescent pervasive developmental disorder
    • Hollander E., Wasserman S., Swanson E.N., et al. A double-blind placebo-controlled pilot study of olanzapine in childhood/adolescent pervasive developmental disorder. J Child Adolesc Psychopharmacol 16 5 (2006) 541-548
    • (2006) J Child Adolesc Psychopharmacol , vol.16 , Issue.5 , pp. 541-548
    • Hollander, E.1    Wasserman, S.2    Swanson, E.N.3
  • 40
    • 50449096017 scopus 로고    scopus 로고
    • Available at: Accessed May 16, 2008
    • ClinicalTrials.gov. Available at:. http://www.clinicaltrials.gov Accessed May 16, 2008
    • ClinicalTrials.gov1
  • 41
    • 34548154296 scopus 로고    scopus 로고
    • Treating autism pharmacologically: also tacrine might improve symptomatology in some cases
    • Niederhofer H. Treating autism pharmacologically: also tacrine might improve symptomatology in some cases. J Child Neurol 22 8 (2007) 1054
    • (2007) J Child Neurol , vol.22 , Issue.8 , pp. 1054
    • Niederhofer, H.1
  • 42
    • 0036749941 scopus 로고    scopus 로고
    • A retrospective open trial of adjunctive donepezil in children and adolescents with autistic disorder
    • Hardan A.Y., and Handen B.L. A retrospective open trial of adjunctive donepezil in children and adolescents with autistic disorder. J Child Adolesc Psychopharmacol 12 3 (2002) 237-241
    • (2002) J Child Adolesc Psychopharmacol , vol.12 , Issue.3 , pp. 237-241
    • Hardan, A.Y.1    Handen, B.L.2
  • 43
    • 31644439693 scopus 로고    scopus 로고
    • Donepezil in the treatment of ADHD-like symptoms in youths with pervasive developmental disorder: a case series
    • Doyle R.L., Frazier J., Spencer T.J., et al. Donepezil in the treatment of ADHD-like symptoms in youths with pervasive developmental disorder: a case series. J Atten Disord 9 3 (2006) 543-549
    • (2006) J Atten Disord , vol.9 , Issue.3 , pp. 543-549
    • Doyle, R.L.1    Frazier, J.2    Spencer, T.J.3
  • 44
    • 85013589858 scopus 로고    scopus 로고
    • Donepezil hydrochloride: a double-blind study in autistic children
    • Chez M.G., Buchanan T.M., Becker M., et al. Donepezil hydrochloride: a double-blind study in autistic children. J Pediatr Neurol 1 2 (2003) 83-88
    • (2003) J Pediatr Neurol , vol.1 , Issue.2 , pp. 83-88
    • Chez, M.G.1    Buchanan, T.M.2    Becker, M.3
  • 45
    • 2342436849 scopus 로고    scopus 로고
    • Treating autistic spectrum disorders in children: utility of the cholinesterase inhibitor rivastigmine tartrate
    • Chez M.G., Aimonovitch M., Buchanan T., et al. Treating autistic spectrum disorders in children: utility of the cholinesterase inhibitor rivastigmine tartrate. J Child Neurol 19 3 (2004) 165-169
    • (2004) J Child Neurol , vol.19 , Issue.3 , pp. 165-169
    • Chez, M.G.1    Aimonovitch, M.2    Buchanan, T.3
  • 46
    • 33750960154 scopus 로고    scopus 로고
    • A prospective, open-label trial of galantamine in autistic disorder
    • Nicolson R., Craven-Thuss B., and Smith J. A prospective, open-label trial of galantamine in autistic disorder. J Child Adolesc Psychopharmacol 16 5 (2006) 621-629
    • (2006) J Child Adolesc Psychopharmacol , vol.16 , Issue.5 , pp. 621-629
    • Nicolson, R.1    Craven-Thuss, B.2    Smith, J.3
  • 47
    • 0022412296 scopus 로고
    • Children's Psychiatric Rating Scale
    • Fish B. Children's Psychiatric Rating Scale. Psychopharmacol Bull 21 (1985) 753-770
    • (1985) Psychopharmacol Bull , vol.21 , pp. 753-770
    • Fish, B.1
  • 48
    • 0031880046 scopus 로고    scopus 로고
    • Hypothesis: is infantile autism a hypoglutamatergic disorder? Relevance of glutamate-serotonin interactions for pharmacotherapy
    • Carlsson M.L. Hypothesis: is infantile autism a hypoglutamatergic disorder? Relevance of glutamate-serotonin interactions for pharmacotherapy. J Neural Transm 105 4-5 (1998) 525-535
    • (1998) J Neural Transm , vol.105 , Issue.4-5 , pp. 525-535
    • Carlsson, M.L.1
  • 49
    • 50449095861 scopus 로고    scopus 로고
    • Erickson CA, McDougle CJ, Stigler KA, et al. Glutamatergic function in autism. In: Heresco-Levy U, editor. Glutamate in neuropsychiatric disorders. Trivandrum, Kerala (India): Research Signpost, in press.
    • Erickson CA, McDougle CJ, Stigler KA, et al. Glutamatergic function in autism. In: Heresco-Levy U, editor. Glutamate in neuropsychiatric disorders. Trivandrum, Kerala (India): Research Signpost, in press.
  • 50
    • 0011474149 scopus 로고    scopus 로고
    • The diverse role of L-glutamic acid in brain signal transduction
    • Davis K.L., Charney D., Coyle J.T., et al. (Eds), Lippincott Williams & Williams, Philadelphia
    • Coyle J.T., Leski M.L., and Morrison J.H. The diverse role of L-glutamic acid in brain signal transduction. In: Davis K.L., Charney D., Coyle J.T., et al. (Eds). Neuropsychopharmacology: the fifth generation of progress (2002), Lippincott Williams & Williams, Philadelphia 71-90
    • (2002) Neuropsychopharmacology: the fifth generation of progress , pp. 71-90
    • Coyle, J.T.1    Leski, M.L.2    Morrison, J.H.3
  • 51
    • 0028598399 scopus 로고
    • Intractable epilepsy in children. The efficacy of lamotrigine treatment, including non-seizure-related benefits
    • Uvebrant P., and Bauziene R. Intractable epilepsy in children. The efficacy of lamotrigine treatment, including non-seizure-related benefits. Neuropediatrics 25 6 (1994) 284-289
    • (1994) Neuropediatrics , vol.25 , Issue.6 , pp. 284-289
    • Uvebrant, P.1    Bauziene, R.2
  • 52
    • 0030484903 scopus 로고    scopus 로고
    • Open trial lamotrigine in the treatment of self-injurious behavior in an adolescent with profound mental retardation
    • Davanzo P.A., and King B.H. Open trial lamotrigine in the treatment of self-injurious behavior in an adolescent with profound mental retardation. J Child Adolesc Psychopharmacol 6 4 (1996) 273-279
    • (1996) J Child Adolesc Psychopharmacol , vol.6 , Issue.4 , pp. 273-279
    • Davanzo, P.A.1    King, B.H.2
  • 53
    • 0035321893 scopus 로고    scopus 로고
    • Lamotrigine therapy for autistic disorder: a randomized, double-blind, placebo-controlled trial
    • Belsito K.M., Law P.A., Kirk K.S., et al. Lamotrigine therapy for autistic disorder: a randomized, double-blind, placebo-controlled trial. J Autism Dev Disord 31 2 (2001) 175-181
    • (2001) J Autism Dev Disord , vol.31 , Issue.2 , pp. 175-181
    • Belsito, K.M.1    Law, P.A.2    Kirk, K.S.3
  • 55
    • 0024369122 scopus 로고
    • Autism diagnostic observation schedule: a standardized observation of communicative and social behavior
    • Lord C., Rutter M., Goode S., et al. Autism diagnostic observation schedule: a standardized observation of communicative and social behavior. J Autism Dev Disord 19 2 (1989) 185-212
    • (1989) J Autism Dev Disord , vol.19 , Issue.2 , pp. 185-212
    • Lord, C.1    Rutter, M.2    Goode, S.3
  • 56
    • 0032902238 scopus 로고    scopus 로고
    • A placebo-controlled trial of D-cycloserine added to conventional neuroleptics in patients with schizophrenia
    • Goff D.C., Tsai G., Levitt J., et al. A placebo-controlled trial of D-cycloserine added to conventional neuroleptics in patients with schizophrenia. Arch Gen Psychiatry 56 1 (1999) 21-27
    • (1999) Arch Gen Psychiatry , vol.56 , Issue.1 , pp. 21-27
    • Goff, D.C.1    Tsai, G.2    Levitt, J.3
  • 57
    • 0036184549 scopus 로고    scopus 로고
    • Placebo-controlled trial of D-cycloserine added to conventional neuroleptics, olanzapine, or risperidone in schizophrenia
    • Heresco-Levy U., Ermilov M., Shimoni J., et al. Placebo-controlled trial of D-cycloserine added to conventional neuroleptics, olanzapine, or risperidone in schizophrenia. Am J Psychiatry 159 3 (2002) 480-482
    • (2002) Am J Psychiatry , vol.159 , Issue.3 , pp. 480-482
    • Heresco-Levy, U.1    Ermilov, M.2    Shimoni, J.3
  • 58
    • 35748969317 scopus 로고    scopus 로고
    • The Cognitive and Negative Symptoms in Schizophrenia Trial (CONSIST): the efficacy of glutamatergic agents for negative symptoms and cognitive impairments
    • Buchanan R.W., Javitt D.C., Marder S.R., et al. The Cognitive and Negative Symptoms in Schizophrenia Trial (CONSIST): the efficacy of glutamatergic agents for negative symptoms and cognitive impairments. Am J Psychiatry 164 10 (2007) 1593-1602
    • (2007) Am J Psychiatry , vol.164 , Issue.10 , pp. 1593-1602
    • Buchanan, R.W.1    Javitt, D.C.2    Marder, S.R.3
  • 59
    • 7444237570 scopus 로고    scopus 로고
    • A pilot study of D-cycloserine in subjects with autistic disorder
    • Posey D.J., Kem D.L., Swiezy N.B., et al. A pilot study of D-cycloserine in subjects with autistic disorder. Am J Psychiatry 161 11 (2004) 2115-2117
    • (2004) Am J Psychiatry , vol.161 , Issue.11 , pp. 2115-2117
    • Posey, D.J.1    Kem, D.L.2    Swiezy, N.B.3
  • 60
    • 14344274335 scopus 로고    scopus 로고
    • Case series: amantadine open-label treatment of impulsive and aggressive behavior in hospitalized children with developmental disabilities
    • King B.H., Wright D.M., Snape M., et al. Case series: amantadine open-label treatment of impulsive and aggressive behavior in hospitalized children with developmental disabilities. J Am Acad Child Adolesc Psychiatry 40 6 (2001) 654-657
    • (2001) J Am Acad Child Adolesc Psychiatry , vol.40 , Issue.6 , pp. 654-657
    • King, B.H.1    Wright, D.M.2    Snape, M.3
  • 61
    • 14344267755 scopus 로고    scopus 로고
    • Double-blind, placebo-controlled study of amantadine hydrochloride in the treatment of children with autistic disorder
    • King B.H., Wright D.M., Handen B.L., et al. Double-blind, placebo-controlled study of amantadine hydrochloride in the treatment of children with autistic disorder. J Am Acad Child Adolesc Psychiatry 40 6 (2001) 658-665
    • (2001) J Am Acad Child Adolesc Psychiatry , vol.40 , Issue.6 , pp. 658-665
    • King, B.H.1    Wright, D.M.2    Handen, B.L.3
  • 62
    • 33745887507 scopus 로고    scopus 로고
    • Memantine for disruptive behavior in autistic disorder
    • Erickson C.A., and Chambers J.E. Memantine for disruptive behavior in autistic disorder. J Clin Psychiatry 67 6 (2006) 1000
    • (2006) J Clin Psychiatry , vol.67 , Issue.6 , pp. 1000
    • Erickson, C.A.1    Chambers, J.E.2
  • 63
    • 33847170993 scopus 로고    scopus 로고
    • A retrospective study of memantine in children and adolescents with pervasive developmental disorders
    • Erickson C.A., Posey D.J., Stigler K.A., et al. A retrospective study of memantine in children and adolescents with pervasive developmental disorders. Psychopharmacology (Berl) 191 1 (2007) 141-147
    • (2007) Psychopharmacology (Berl) , vol.191 , Issue.1 , pp. 141-147
    • Erickson, C.A.1    Posey, D.J.2    Stigler, K.A.3
  • 64
    • 34250731835 scopus 로고    scopus 로고
    • Memantine as adjunctive therapy in children diagnosed with autistic spectrum disorders: an observation of initial clinical response and maintenance tolerability
    • Chez M.G., Burton Q., Dowling T., et al. Memantine as adjunctive therapy in children diagnosed with autistic spectrum disorders: an observation of initial clinical response and maintenance tolerability. J Child Neurol 22 5 (2007) 574-579
    • (2007) J Child Neurol , vol.22 , Issue.5 , pp. 574-579
    • Chez, M.G.1    Burton, Q.2    Dowling, T.3
  • 65
    • 34248589702 scopus 로고    scopus 로고
    • Glutamate antagonists seem to be slightly effective in psychopharmacologic treatment of autism
    • Niederhofer H. Glutamate antagonists seem to be slightly effective in psychopharmacologic treatment of autism. J Clin Psychopharmacol 27 3 (2007) 317-318
    • (2007) J Clin Psychopharmacol , vol.27 , Issue.3 , pp. 317-318
    • Niederhofer, H.1
  • 66
    • 33750950870 scopus 로고    scopus 로고
    • A prospective, open-label trial of memantine in the treatment of cognitive, behavioral, and memory dysfunction in pervasive developmental disorders
    • Owley T., Salt J., Guter S., et al. A prospective, open-label trial of memantine in the treatment of cognitive, behavioral, and memory dysfunction in pervasive developmental disorders. J Child Adolesc Psychopharmacol 16 5 (2006) 517-524
    • (2006) J Child Adolesc Psychopharmacol , vol.16 , Issue.5 , pp. 517-524
    • Owley, T.1    Salt, J.2    Guter, S.3
  • 67
    • 33845509491 scopus 로고    scopus 로고
    • A placebo double-blind pilot study of dextromethorphan for problematic behaviors in children with autism
    • Woodard C., Groden J., Goodwin M., et al. A placebo double-blind pilot study of dextromethorphan for problematic behaviors in children with autism. Autism 11 1 (2007) 29-41
    • (2007) Autism , vol.11 , Issue.1 , pp. 29-41
    • Woodard, C.1    Groden, J.2    Goodwin, M.3
  • 68
    • 33748093784 scopus 로고    scopus 로고
    • The neuroscience of affiliation: forging links between basic and clinical research on neuropeptides and social behavior
    • Bartz J.A., and Hollander E. The neuroscience of affiliation: forging links between basic and clinical research on neuropeptides and social behavior. Horm Behav 50 4 (2006) 518-528
    • (2006) Horm Behav , vol.50 , Issue.4 , pp. 518-528
    • Bartz, J.A.1    Hollander, E.2
  • 69
    • 33846624633 scopus 로고    scopus 로고
    • Oxytocin increases retention of social cognition in autism
    • Hollander E., Bartz J., Chaplin W., et al. Oxytocin increases retention of social cognition in autism. Biol Psychiatry 61 4 (2007) 498-503
    • (2007) Biol Psychiatry , vol.61 , Issue.4 , pp. 498-503
    • Hollander, E.1    Bartz, J.2    Chaplin, W.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.