Ethanol exposure during late gestation and nursing in the rat: Effects upon maternal care, ethanol metabolism and infantile milk intake

Pharmacology Biochemistry and Behavior

Volumn 91, Issue 1, 2008, Pages 21-31

  Pueta, Mariana ^a,c,d   Abate, Paula ^a,c   Haymal, Olga B ^a   Spear, Norman E ^b   Molina, Juan C ^a,b,c  

^a Facultad de Ciencias Naturales e Instituto M Lillo   (Argentina)

^b BINGHAMTON UNIVERSITY   (United States)

^c UNIVERSIDAD NACIONAL DE CÓRDOBA   (Argentina)

^d Fac de Cs Exactas   (Argentina)

Author keywords

Ethanol; Gestation; Lactation; Maternal care; Metabolism; Suckling

Indexed keywords

ALCOHOL;

ALCOHOL INTOXICATION; ALCOHOL METABOLISM; ANIMAL EXPERIMENT; ARTICLE; BEHAVIOR MODIFICATION; BREAST FEEDING; CONTROLLED STUDY; FEMALE; INFANT FEEDING; MALE; MATERNAL CARE; MOUSE; NONHUMAN; PRENATAL EXPOSURE; PRIORITY JOURNAL; SUCKLING; THIRD TRIMESTER PREGNANCY;

ALCOHOLIC INTOXICATION; ANIMALS; ANIMALS, NEWBORN; ANIMALS, SUCKLING; BIRTH WEIGHT; CENTRAL NERVOUS SYSTEM DEPRESSANTS; ETHANOL; FEMALE; LACTATION; LITTER SIZE; MATERNAL BEHAVIOR; POSTPARTUM PERIOD; PREGNANCY; RATS; RATS, WISTAR; WEIGHT GAIN;

RATTUS;

EID: 50349085395     PISSN: 00913057     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.pbb.2008.06.007     Document Type: Article

References (84)

1. Abate P., Pueta M., Spear N.E., and Molina J.C. Fetal learning about ethanol and later ethanol responsiveness: evidence against "safe" amounts of prenatal exposure. Exp Biol Med 233 (2008) 139-154
2. Abate P., Varlinskaya E.I., Cheslock S.J., Spear N.E., and Molina J.C. Neonatal activation of alcohol-relate prenatal memories: Impact upon the first suckling response. Alcohol Clin Exp Res 26 (2002) 989-998
3. Abel E.L., Greizerstein H.B., and Siemens A.J. Influence of lactation on rate of disappearance of ethanol in the rat. Neurobehav Toxicol 1 (1979) 185-186
4. Alberts J.R., and Gubernick D.J. Reciprocity and resource exchange. A symbiotic model of parent-offspring relations. In: Rosenblum L.A., and Moltz H. (Eds). Symbiosis in Parent-Offspring Interactions (1983), Plenum, New York 7-44
5. Arias C., and Chotro M.G. Increased preference for ethanol in the infant rat after prenatal ethanol exposure, expressed on intake and taste reactivity tests. Alcohol Clin Exp Res 29 (2005) 337-346
6. Arrati P.G., Carmona C., Dominguez G., Beyer C., and Rosenblatt J.S. GABA receptor agonist in the medial preoptic area and maternal behavior in lactating rats. Physiol Behav 87 (2006) 51-65
7. Bachmanov A.A., Kiefer S.W., Molina J.C., Tordoff M.G., Duffy V.B., Bartoshuk L.M., et al. Chemosensory factors influencing alcohol perception, preferences and consumption. Alcohol Clin Exp Res 27 (2003) 220-231
8. Blass E.M. Suckling: determinants, changes, mechanisms, and lasting impressions. Dev Psychology 26 (1990) 520-533
9. Bridges R.S., and Ronsheim P.M. Prolactin (PRL) regulation of maternal behavior in rats: brocriptine treatment delays and PRL promotes the rapid onset of behavior. Endocrinology 126 (1990) 837-848
10. Bridges R.S., Robertson M.C., Shiu R.P.C., Sturgis J.D., Henriquez B.M., and Mann P.E. Central lactogenic regulation of maternal behavior in rats: steroid dependence, hormone specificity and behavioral potencies in rat prolactin and rat placental lactogen I. Endocrinology 138 (1997) 756-763
11. Brunton P.J., and Russell J.A. The expectant brain: adapting for motherhood. Nat Rev Neurosci 9 (2008) 11-25
12. Cagetti E., Liang J., Spigelman I., and Olsen R.W. Withdrawal from chronic intermittent ethanol treatments changes subunit composition, reduces synaptic function, and decreases behavioral responses to positive allosteric modulators of GABAA receptors. Mol Pharmacol 63 (2003) 53-64
13. Chotro M.G., Arias C., and Laviola G. Increased ethanol intake after prenatal ethanol exposure: studies with animals. Neurosci Biobehav Rev 31 (2007) 181-191
14. da-Silva V.A., MaLean A.E., and Beales D. Ethanol elimination by rats as a function of reproductive state, gender and nutricional status. Braz J Med Biol Res 26 (1996) 1097-1103
15. David A.L., Kotecha M., and Girling J.C. Factors influencing postnatal liver function test. Br J Obstet Gynaecol 107 (2000) 1421-1426
16. DeSantiago S., Torres N., and Tovar A.R. Leucine catabolism in mammary tissue, liver and skeletal muscle of dam rat during lactation and weaning. Arch Med Res 29 (1998) 25-32
17. Domínguez H.D., López M.F., Chotro M.G., and Molina J.C. Perinatal responsiveness to alcohol's chemosensory cues as a function of prenatal alcohol administration during gestational days 17-20 in the rat. Neurobiol Learn Mem 65 (1996) 103-112
18. Domínguez H.D., López M.F., and Molina J.C. Neonatal responsiveness to alcohol odor and infant alcohol intake as a function of alcohol experience during late gestation. Alcohol 16 (1998) 109-117
19. Dominguez H.D., Lopez M.F., and Molina J.C. Interactions between perinatal and neonatal associative learning defined by contagious olfactory and tactile stimulation. Neurobiol Learn Mem 71 (1999) 272-288
20. Faas A.E., Spontón E.D., Moya P.R., and Molina J.C. Differential responsiveness to alcohol odor in human neonates: effects of maternal consumption during gestation. Alcohol 22 (2000) 7-17
21. Fleming A.S., O'Day D.H., and Kraemer G.W. Neurobiology of mother-infant interactions: experience and central nervous system plasticity across development and generations. Neurosc Biobehav Reviews 23 (1999) 673-685
22. Fuchs A. Ethanol and the inhibition of oxytocin release in lactating rats. Acta Endocrinol 62 (1969) 546-559
23. Galef Jr. B.G., and Henderson P.W. Mother's milk: a determinant of the feeding preferences of weaning rat pups. J Comp Physiol Psychol 2 (1972) 213-219
24. Galef Jr. B.G., and Sherry D.F. Mother's milk: a medium for transmission of cues reflecting the flavor of mother's diet. J Comp Physiol Psychol 3 (1973) 374-378
25. Giglia R.C., and Binns C.W. Patterns of alcohol intake of pregnant and lactating women in Perth, Australia. Drug Alcohol Rev 26 (2007) 493-500
26. Gonzalez A., Lovic V., Ward G.R., Wainwright P.E., and Fleming A.S. Intergenerational effects of complete maternal deprivation and replacement stimulation on maternal behavior and emotionality on female rats. Dev Psychobiol 38 (2001) 11-32
27. Gordon B.H., Barahona E., Miyakawa H., Finkelman F., and Liebre C.S. Exaggerated acetaldehyde response after ethanol administration during pregnancy and lactation in rats. Alcohol Clin Exp Res 9 (1985) 17-22
28. Hammond K.A. Adaptation of the maternal intestine during lactation. J Mammary Gland Biol Neoplasia 2 (1997) 243-252
29. Heil S.H., Marappa G., and Subramanian M.G. Alcohol and the hormonal control of lactation. Alcohol Health Res World 22 (1998) 178-184
30. Heil S.H., and Subramanian M.G. Chronic alcohol exposure and lactation: extended observations. Alcohol 21 (2000) 127-132
31. Hunt P.S., Kraebel K.S., Rabine H., Spear L.P., and Spear N.E. Enhanced ethanol intake in preweanling rats following exposure to ethanol in a nursing context. Dev Psychobiol 26 (1993) 133-153
32. Hunt P.S., Lant G.M., and Carroll C.A. Enhanced intake of ethanol in preweanling rats following interactions with intoxicated siblings. Dev Psychobiol 37 (2000) 90-99
33. Jacobson S.W. Assessing the impact of maternal drinking during and after pregnancy. Alcohol Health Res World 21 (1997) 199-203
34. Kalant A. Pharmacokinetics of ethanol: absorption, distribution and elimination. In: Begleiter H., and Kissin B. (Eds). The Pharmacology of Alcohol and Alcohol Dependence (1996), Oxford University Press, New York 15-58
35. Kinsley C.H. Developmental psychobiological influences on rodent parental behavior. Neurosci Biobehav Rev 18 (1994) 269-280
36. Knott T.K., Dopico A.M., Dayanithi G., Lemos J., and Treistman S.N. Integrated channel plasticity contributes to alcohol tolerance in neurohypohysial terminals. Mol Pharmacol 62 (2002) 135-142
37. A receptor plasticity after ethanol intoxication. J Neurosci 27 (2007) 12367-12377
38. Little R.E., Northstone K., Golding J., and ALSPAC Study Team. Alcohol, breastfeeding, and development at 18 months. Pediatrics 109 (2002) E72-E77
39. A receptors in the rat brain. Brain Res 1174 (2007) 47-52
40. McLeod D., Pullon S., Cookson T., and Cornford E. Factors influencing alcohol consumption during pregnancy and after giving birth. N Z Med J 115 (2002) U29
41. Mennella J.A. Infant's suckling responses to the flavor of alcohol in mother's milk. Alcohol Clin Exp Res 21 (1997) 581-585
42. Mennella J.A. Alcohol's effect on lactation. Alcohol Res Health 21 (2001) 230-240
43. Mennella J.A. Regulation of milk intake after exposure to alcohol in mother's milk. Alcohol Clin Exp Res 25 (2001) 590-593
44. Mennella J.A., and Beauchamp G.K. The transfer of alcohol to human milk. Effects on flavor and the infant's behavior. N Engl J Med 325 (1991) 981-985
45. Mennella J.A., and Beauchamp G.K. Effects of beer on breast-fed infants. JAMA 269 (1993) 1635-1636
46. Mennella J.A., and Beauchamp G.K. Mothers' milk enhances the acceptance of cereal during weaning. Pediatr Res 41 (1997) 188-192
47. Mennella J.A., and Garcia P.L. Children's hedonic response to the smell of alcohol: Effects of parental drinking habits. Alcohol Clin Exp Res 24 (2000) 1167-1171
48. Mennella J.A., Pepino M.Y., and Teff K.L. Acute alcohol consumption disrupts the hormonal milieu of lactating women. J Clin Endocrinol Metab 90 (2005) 1979-1985
49. Mennella J.A., and Pepino M.Y. Short-term effects of alcohol consumption on the hormonal milieu and mood states in nulliparous women. Alcohol 38 (2006) 29-36
50. Molina J.C., and Chotro M.G. Acute alcohol intoxication paired with appetitive reinforcement: effects upon ethanol intake in infant rats. Behav Neural Biol 51 (1989) 326-345
51. Molina J.C., and Chotro M.G. Acute alcohol intoxication paired with aversive reinforcement: ethanol odor as a conditioned reinforcer in rat pups. Behav Neural Biol 52 (1989) 1-19
52. Molina J.C., Chotro M.G., and Domínguez H.D. Fetal alcohol learning derived from ethanol contamination of the prenatal environment. In: Lecanuet J.P., Fifer W.P., Krasnegor N.A., and Smotherman W.P. (Eds). Fetal development: A psychobiological perspective (1995), Lawrence Erlbaum Associates, Hillsdale, New Jersey 295-315
53. Molina J.C., Pepino M.Y., Johnson J., and Spear N.E. The infant rat learns about alcohol through interaction with an intoxicated mother. Alcohol Clin Exp Res 24 (2000) 428-437
54. Molina J.C., Spear N.E., Spear L.P., Mennella J.A., and Lewis M.J. Alcohol and development: Beyond Fetal Alcohol Syndrome. Dev Psychobiol 49 (2007) 227-242
55. National Institute of Health. Institute of Laboratory Animal Resources, Commission on Life Sciences. National Research Council. Guide for the Care and Use of Laboratory Animals (1996), National Academy Press, Washington, DC
56. Nizhnikov M.E., Molina J.C., Varlinskaya E.I., and Spear N.E. Prenatal ethanol increases postnatal ethanol reinforcement. Alcohol Clin Exp Res 30 (2006) 34-45
57. Numan M., Numan M.J., Schwarz J.M., Neumer C.M., Flood T.F., and Smith C.D. Medial preoptic area interactions with the nucleus accumbens-ventral pallidum circuit and maternal behavior in rats. Behav Brain Res 158 (2005) 53-68
58. Parackal S., Ferguson E., and Harraway J. Alcohol and tobacco consumption among 6-24 months post-partum New Zealand women. Matern Child Nutr 3 (2007) 40-51
59. Pedersen C.A., and Prange Jr. A.J. Evidence that central oxytocin plays a role in the activation of maternal behavior. In: Krasnegor N.A., Blass E.M., Hofer M.A., and Smotherman W.P. (Eds). Perinatal Development: A Psychobiological Perspective (1987), Academic Press, Orlando, Florida 299-320
60. Pepino M.Y., Kraebel K.S., López M.F., Spear N.E., and Molina J.C. Behavioral detection of low concentrations of ethanol in the preweanling rat. Alcohol 15 (1998) 337-353
61. Pepino M.Y., López M.F., Spear N.E., and Molina J.C. Infant rats respond differently to alcohol after nursing from an alcohol-intoxicated dam. Alcohol 18 (1999) 189-201
62. Pepino M.Y., Land C.I., Campbell J., Spear N.E., and Molina J.C. Infantile experience with an alcohol-intoxicated mother: responsiveness to isolation and to specific social interactions (abstract 486). Alcohol Clin Exp Res 5 (2000) 87A
63. Pepino M.Y., Abate P., Spear N.E., and Molina J.C. Disruption of maternal behavior by alcohol intoxication in the lactating rat: a behavioral and metabolic analysis. Alcohol Clin Exp Res 26 (2002) 1205-1214
64. Pepino M.Y., and Mennella J.A. Advice given to women in Argentina about breastfeeding and the use of alcohol. Rev Panam Salud Publica 16 (2004) 408-414
65. Petrov E.S., Varlinskaya E.I., and Spear N.E. Reinforcement from pharmacological effects of ethanol in newborn rats. Alcohol Clin Exp Res 27 (2003) 1583-1591
66. Ponce L.F., Pautassi R.M., Spear N.E., and Molina J.C. Nursing from an ethanol-intoxicated dam induces short- and long-term disruptions in motor performance and enhances later self-administration of the drug. Alcohol Clin Exp Res 28 (2004) 1039-1050
67. Pueta M., Abate P., Spear N.E., and Molina J.C. Interaction between pre- and early postnatal alcohol-related memories: Impact upon alcohol acceptance patterns. Int J Comp Psychol 18 (2005) 207-224
68. Rosenblatt J.S., and Snowdon C.T. Parental care: evolution, mechanisms and adaptative significance. Advances in the study of behavior vol. 25 (1996), Academic Press, New York
69. Rosenblatt J.S. Biological and behavioral factors underlying in the onset and maintenance of maternal behavior in the rat. In: Krasnegor N.A., Blass E.M., Hofer M.A., and Smotherman W.P. (Eds). Perinatal Development: A Psychobiological Perspective (1987), Academic Press, Orlando, Florida 323-341
70. Roth T.L., Wilson D.A., and Sullivan R.M. Neurobehavioral development of infant learning and memory: implications for infant attachment. In: Slater P.J.B., Rosenblatt J.S., Snowdon C.T., Roper T.J., Brockman H.J., and Naguib M. (Eds). Advances in the study of behavior (2004), Academic Press, San Diego 103-133
71. Schaal B., Coureaud G., Marlier L., and Soussignan R. Fetal olfactory cognition preadapts neonatal behavior in mammals. In: Marchlewska-Koj A., Lepri J.L., and Muller-Schwarze (Eds). Chemical Signals in Vertebrates vol. 9 (2001), Kluwer Acxademic/Plenum Publishers, New York 197-204
72. Schaal B., Hummel T., and Soussignan R. Olfaction in the fetal and premature infant: functional status and clinical implications. Clin Perinatol 31 (2004) 261-285
73. Smotherman W.P., and Robinson S.R. The rat fetus in its environment: behavioral adjustments to novel, familiar, aversive and conditioned stimuli presented in utero. Behav Neurosci 99 (1985) 521-530
74. Spear N.E., and Molina J.C. Fetal or infantile exposure to ethanol promotes ethanol ingestion in adolescence and adulthood: a theoretical review. Alcohol Clin Exp Res 29 (2005) 909-929
75. Stack E.C., Balakrishnan R., Numan M.J., and Numan M. A functional neuroanatomical investigation of the role of the medial proptic area in neural circuits regulating maternal behavior. Behav Brain Res 131 (2002) 17-36
76. Stamps J. Behavioural processes affecting development: Tinbergen's fourth question comes of age. Anim. Behav. 66 (2003) 1-13
77. Subramanian M.G. Effects of chronic alcohol administration on lactational performance in the rat. Alcohol 12 (1995) 137-143
78. Subramanian M.G. Evaluation of lactational parameters after alcohol administration for four days during early or midlactation in the rat. Alcohol Clin Exp Res 21 (1997) 799-803
79. Subramanian M.G. Alcohol inhibits suckling-induced oxytocin release in the lactating rat. Alcohol 19 (1999) 51-55
80. Subramanian M.G., Chen X.G., and Bergeski B.A. Pattern and duration of the inhibitory effect of alcohol administered acutely on suckling-induced prolactin in lactating rats. Alcohol Clin Exp Res 14 (1990) 771-775
81. Svennersten-Sjaunja K., and Olsson K. Endocrinology of milk production. Domest Anim Endocrinol 29 (2005) 241-258
82. Thiels E., Alberts J.R., and Cramer C.P. Weaning in Rats: II. Pup behavior patterns. Dev Psychobiol 23 (1990) 495-510
83. Vilaro S., Viñas O., Remesar X., and Herrera E. Effects of chronic ethanol consumption on lactational performance in rat: mammary gland and milk composition and pups' growth and metabolism. Pharmacol Biochem Behav 27 (1987) 333-339
84. Widmer H., Ludwing M., Bancel F., Leng G., and Dayanithi G. Neurosteroid regulation of oxytocin and vasopressin release from the rat supraoptic nucleus. J Physiol 548 (2003) 233-244