Behavioral detection of low concentrations of ethanol in milk in the preweanling rat

Alcohol

Volumn 15, Issue 4, 1998, Pages 337-353

  Pepino, Marta Yanina ^a   Kraebel, Kimberly S ^b   López, Marcelo F ^a   Spear, Norman E ^b   Molina, Juan Carlos ^a  

^a INSTITUTO DE INVESTIGACIÓN MÉDICA MERCEDES Y MARTÍN FERREYRA   (Argentina)

^b BINGHAMTON UNIVERSITY   (United States)

Author keywords

Associative learning; Behavioral detection; Conditioned stimulus; Ethanol; Habituation; Heart rate; Locomotion; Milk; Mouthing; Nursing; Preweanling rat; Unconditioned stimulus

Indexed keywords

ALCOHOL;

ALCOHOL INTOXICATION; ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BREAST FEEDING; CONTROLLED STUDY; DRUG MILK LEVEL; HABITUATION; HEART RATE; LOCOMOTION; MILK; NONHUMAN; RAT; STATE DEPENDENT LEARNING; TASTE AVERSION; WEANING; WEIGHT GAIN;

ANIMALS; ANIMALS, SUCKLING; AVOIDANCE LEARNING; BEHAVIOR, ANIMAL; CONDITIONING (PSYCHOLOGY); DOSE-RESPONSE RELATIONSHIP, DRUG; ETHANOL; FEMALE; HABITUATION, PSYCHOPHYSIOLOGIC; MILK; OSMOLAR CONCENTRATION; RATS; RATS, WISTAR; WEIGHT GAIN;

EID: 0031924362     PISSN: 07418329     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0741-8329(97)00154-7     Document Type: Article

References (63)

1. Bice P. J., Kiefer S. W. Taste reactivity in alcohol preferring and nonpreferring rats. Alcohol. Clin. Exp. Res. 14:1990;721-727.
2. Campbell B. A., Alberts J. K. Ontogeny of long-term memory for learned taste aversion. Behav. Neural Biol. 25:1979;139-156.
3. Campbell B. A., Stehouer D. J. Ontogeny of habituation and sensitization in the rat. Spear N. E., Campbell B. A. Ontogeny of learning and memory. 1979;67-100 Lawrence Erlbaum Associates, Hillsdale, NJ.
4. Chotro M. G., Molina J. C. Bradycardiac responses elicited by ethanol odor in rat neonates. Influence of in utero experience with ethanol Psychopharmacology (Berlin). 106:1992;491-496.
5. Chotro M. G., Kraebel K., McKinzie D. L., Molina J. C., Spear N. E. Prenatal and postnatal ethanol exposure influences preweanling rats' behavioral and autonomic responding to ethanol odor. Alcohol. 13:1996;377-385.
6. Cobo E. Effect of different doses of ethanol on the milk-ejecting reflex in lactating women. Am. J. Obstet. Gynecol. 115:1973;817-821.
7. Cohen L. B., Gelber E. R. Infant visual memory. Cohen L., Salapatek P. Infant perception. From sensation to cogntion, vol. 1:1975;Academic Press, New York.
8. Coombes S., Revusky S., Lett B. Long-delay taste aversions in an unpoisoned rat. Exposure to a poisoned rat as the US Learn. Motiv. 11:1980;256-266.
9. Dailey W., Amsel A. Ontogeny of heart rate response to milk infusion in infant rats as a function of level of deprivation. Behav. Neurosci. 97:1983;470-477.
10. Dittmer D. S. Blood and other body fluids. 1961;Federation of American Societies for Experimental Biology, Washington, DC.
11. Domínguez H. D., Bocco G., Chotro M. G., Spear N. E., Molina J. C. Operant responding controlled by milk or milk contaminated with alcohol as positive reinforcers in infant rats. Pharmacol. Biochem. Behav. 44:1993;403-409.
12. Domínguez H. D., Bocco G., Chotro M. G., Spear N. E., Molina J. C. Aversions to alcohol's orosensory cues in infant rats. Generalization to compounds of alcohol with sucrose or sodium chloride Alcohol. 11:1994;225-233.
13. Domínguez H. D., Chotro M. G., Molina J. C. Alcohol in the amniotic fluid prior to cesarean delivery. Effects of subsequent exposure to the drug's odor upon alcohol responsiveness Behav. Neural Biol. 60:1993;129-138.
14. Dominguez H. D., Lopez M. F., Chotro M. G., Molina J. C. Perinatal responsiveness to alcohol's chemosensory cues as a function of prenatal alcohol administration during gestational days 17-20 in the rat. Neurobiol. Learn. Mem. 65:1996;103-112.
15. Galef B. G. Jr. Development of flavor preference in man and animals. The role of social and nonsocial factors Aslin R. N., Alberts J. R., Peterson M. R. Development of perception. Psychobiological perspectives:1982;411-431 Academic Press, New York.
16. Galef B. G. Jr., Henderson P. W. Mother's milk. A determinant of the feeding preferences of weaning rat pups J. Comp. Physiol. Psychol. 78:1972;213-219.
17. Guerri C., Sanchis R. Alcohol and acetaldehyde in rat's milk following ethanol administration. Life Sci. 38:1986;1543-1556.
18. Hachenberg H., Schmidt A. P. Gas chromatographic head-space analysis. 1985;John Willey & Sons, New York.
19. Hayashi T., Tadokoro S. Learning retardation and enhanced ethanol preference produced by postnatal pretreatments with ethanol in adult rats. Jpn. J. Pharmacol. 37:1985;269-276.
20. Hoffman H., Molina J. C., Kucharski D., Spear N. E. Further examination of ontogenic limitations on conditioned taste aversion. Dev. Psychobiol. 20:1987;455-463.
21. Hunt P. S., Kraebel K. S., Rabine H., Spear L. P., Spear N. E. Enhanced ethanol intake in preweanling rats following exposure to ethanol in a nursing context. Dev. Psychobiol. 26:1993;133-153.
22. Jones A. W. Alcohol in mother's milk. N. Engl. J. Med. 326:1992;766-767.
23. Kamin J. L. Predictability, surprise, attention, and conditioning. Campbell B. A., Church R. M. Punishment and aversive behavior. 1969;Appleton-Century-Crofts, New York.
24. Kaplan P. S., Werner J. S., Rudy J. W. Habituation, response to novelty, and dishabituation in human infants. Test of a dual-process theory of visual attention Rovee-Collier C., Lipsitt L. P. Advances in infancy resarch, vol. 6. 1990;61-109 Ablex Publishing, Norwood, NJ.
25. Kesaniemi Y. A. Ethanol and acetaldehyde in the milk and peripheral blood of lactating woman after ethanol administration. J. Obstet. Gynaecol. Br. Commonw. 81:1974;84-86.
26. Kiefer S. W. Alcohol, palatability, and taste reactivity. Neurosci. Biobehav. Rev. 19:1995;133-141.
27. Kiefer S. W., Bice P. J., Badia-Elder N. Alterations in taste reactivity to alcohol in rats given continuous alcohol access followed by abstinence. Alcohol. Clin. Exp. Res. 18:1994;555-559.
28. Kucharski D., Spear N. E. Potentiation and overshadowing in preweanling and adult rats. J. Exp. Psychol.:Anim. Behav. Proc. 11:1985;15-34.
29. Lawrence R. A. Breastfeeding. A guide for the medical profession:1994;Mosby, St. Louis.
30. Logue A. Taste aversion and the generality of the laws of learning. Psychol. Bull. 86:1979;276-296.
31. López M. F., Spear N. E., Molina J. C. Ontogenetic differences in the expression of olfactory conditioned aversions resulting from a state of acute alcohol intoxication in the rat. Alcohol. 13:1996;473-481.
32. Lubow R. Latent inhibition. Psychol. Bull. 79:1973;398-407.
33. Mellon R. C., Kraemer P. J., Spear N. E. Intersensory development and Pavlovian conditioning. Stimulus selection and encoding of lights and tones in the preweanling rat JEP. ABP 17:1991;448-464.
34. Mennella J. A. Infant's suckling responses to the flavor of alcohol in mother's milk. Alcohol. Clin. Exp. Res. 21:1997;581-585.
35. Mennella J. A., Beauchamp G. K. The transfer of alcohol to human milk. Effects on flavor and the infant's Behavior. N. Engl. J. Med. 352:1991;981-985.
36. Mennella J. A., Beauchamp G. K. Effects of beer on breast-fed infants. JAMA. 269:1993;1635-1636.
37. Miller J. S., Molina J. C., Spear N. E. Ontogenetic differences in the expression of odor-aversion learning in 4- and 8-day-old rats. Dev. Psychobiol. 23:1990;319-330.
38. Moe, K.; Epstein, A. N.: Sodium preference and sodium appetite of neonatal rats. Paper presented at the annual meeting of the International Society for Developmental Psychobiology. Hyannis, MA; November, 1983.
39. Molina F., Bosque-Sendra J. M., Plas A., Megias L. Determination of ethanol in biological samples by head-space gas chromatography. J. Pharm. Biomed. Anal. 10:1993;1069-1071.
40. Molina J. C., Chotro M. G. Acute alcohol intoxication paired with appetitive reinforcement. Effects upon ethanol intake in infant rats Behav. Neural Biol. 51:1989;326-345.
41. Molina J. C., Chotro M. G. Acute alcohol intoxication paired with aversive reinforcement. Ethanol odor as a conditioned reinforcer in rat pups Behav. Neural Biol. 52:1989;1-19.
42. Molina J. C., Chotro M. G., Spear N. E. Early (preweanling) recognition of ethanol's orosensory cues resulting from acute ethanol intoxication. Behav. Neural Biol. 51:1989;307-325.
43. Molina J. C., Chotro M. G., Domínguez H. D. Fetal alcohol learning resulting from alcohol contamination of the prenatal environment. Lecanuet J. P., Fifer W. P., Krasnegor N. A., Smotherman W. P. Fetal development. A psychobiological perspective:1995;419-438 Lawrence Erlbaum Associates, Hillsdale, NJ.
44. Molina J. C., Serwatka J., Spear N. E. Alcohol drinking patterns of young adult rats as a function of infantile aversive experiences with alcohol odor. Behav. Neural Biol. 46:1986;257-271.
45. Molina J. C., Serwatka J., Spear N. E. Changes in alcohol intake resulting from prior experiences with alcohol odor in young rats. Pharmacol. Biochem. Behav. 21:1984;387-391.
46. Moore E., Stamper C., Diaz J. Artificial rearing of rat pups using rat milk. Dev. Psychobiol. 23:1990;169-178.
47. Nachman M., Rauschenberger J., Ashe J. Stimulus characteristics in food aversion learning. Milgram N., Krames L., Alloway T. Food aversion learning. 1977;105-131 Plenum Press, New York.
48. Pelchat M. L., Grill H. J., Rozin P., Jacobs J. Quality of acquired responses to taste by Rattus norvegicus depends on the type of associated discomfort. J. Comp. Psychol. 97:1983;140-153.
49. Peterson R. G., Bowes W. A. Jr. Drugs, toxins, and environmental agents in breast milk. Neville M. C., Neifert M. R. Lactation. Physiology nutrition and breast-feeding:1983;367-403 Plenum Press, New York.
50. Pohorecky L. A., Brick J. Pharmacology of ethanol. Pharmacol. Ther. 36:1988;335-427.
51. Ronca A. E., Alberts J. R. Heart rate development and sensory-evoked cardiac responses in perinatal rats. Phyisiol. Behav. 47:1990;1075-1082.
52. Rudy J. W., Cheatle M. D. Ontogeny of associative learning. Acquisition of odor aversion in neonatal rats Campbell B. A., Spear N. E. Ontogeny of learning and memory. 1979;157-188 Lawrence Erlbaum Associates, Hillsdale, NJ.
53. Rudy J. W., Vogt M., Hyson R. Developmental analysis of the rat's learned reaction to gustatory and auditory stimulation. Kail R., Spear N. E. Comparative perspectives on the development of memory. 1984;181-208 Lawrence Erlbaum Associates, Hillsdale, NJ.
54. Scott, T. R.: Gustatory control of food selection. In: Stricker, E. M., ed. Handbook of behavioral neurobiology, volume 10: Neurobiology of food and fluid intake. New York: Plenum Press; 1990:243-263.
55. Smotherman W. P., Robinson S. R. Habituation in the rat fetus. Q. J. Exp. Psychol. 44B:1992;215-230.
56. Smotherman W. P., Robinson S. R. Fetal heart rate response to milk predicts expression of the stretch response. Physiol. Behav. 51:1992;833-837.
57. Spear L. P., Spetch S. M., Kirstein C. L., Kuhn C. M. Anterior and posterior, but not cheek, intraoral cannulation procedures elevate serum corticosterone levels in neonatal rat pups. Dev. Psychobiol. 22:1989;401-412.
58. Spear N. E. Behaviours that indicate memory. Levels of expression Can. J. Psychol. 38:1984;348-367.
59. Spear N. E., Rudy J. W. Tests of the ontogeny of learning and memory. Issues, methods, and results Shair H. N., Barr G. A., Hofer M. A. Developmental psychobiology. New methods and changing concepts:1991;84-113 Oxford University Press, New York.
60. Swithers-Mulvey S. E., Hall W. G. Control of ingestion by oral habituation in rat pups. Behav. Neurosci. 106:1992;710-717.
61. Thompson R. F., Spencer W. A. Habituation. A model phenomenon for the study of neuronal substrates of behavior Psychol. Rev. 73:1966;16-43.
62. Vilaró S., Viñas O., Remesar X., Herrera E. Effects of chronic ethanol consumption on lactational performance in rat. Mammary gland and milk composition and pups' growth and metabolism Pharmacol. Biochem. Behav. 27:1987;333-339.
63. Zorzano A., Herrera E. Decreased in vivo rate of ethanol metabolism in the suckling rat. Alcohol. Clin. Exp. Res. 13:1989;527-532.