Neonatal responsiveness to alcohol odor and infant alcohol intake as a function of alcohol experience during late gestation

Alcohol

Volumn 16, Issue 2, 1998, Pages 109-117

  Domínguez, Héctor Daniel ^a   López, Marcelo Fernando ^a   Molina, Juan Carlos ^a  

^a INSTITUTO DE INVESTIGACIÓN MÉDICA MERCEDES Y MARTÍN FERREYRA   (Argentina)

Author keywords

Alcohol intake; Alcohol intoxication; Alcohol odor; Chemosensory processing; Early learning and memory; Fetus; Infantile ingestion; Neonatal activity; Quinine; Sucrose

Indexed keywords

ALCOHOL; QUININE; SUCROSE;

ALCOHOL CONSUMPTION; ALCOHOL INTOXICATION; AMNION FLUID; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BEHAVIOR; CONTROLLED STUDY; FEMALE; FETAL ALCOHOL SYNDROME; HEAD MOVEMENT; LEARNING; MEMORY; MOTOR ACTIVITY; NEWBORN; NONHUMAN; OLFACTORY SYSTEM; PRENATAL DRUG EXPOSURE;

ALCOHOL DRINKING; ALCOHOLIC INTOXICATION; ANIMALS; ANIMALS, NEWBORN; BEHAVIOR, ANIMAL; ETHANOL; FEMALE; GESTATIONAL AGE; MOTOR ACTIVITY; ODORS; PREGNANCY; PRENATAL EXPOSURE DELAYED EFFECTS; RATS; RATS, WISTAR;

ANIMALIA; CINCHONA PUBESCENS;

EID: 0344783795     PISSN: 07418329     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0741-8329(97)00169-9     Document Type: Article

References (47)

1. Abbey H., Howard E. Statistical procedures in developmental studies on species with multiple offspring. Dev. Psychobiol. 6:1973;329-335.
2. Abel E.L., Bush R., Dintcheff B.A. Exposure of rats to alcohol in utero alters drug sensitivity in adulthood. Science. 212:1981;1531-1533.
3. Abel E.L. Fetal alcohol syndrome and fetal alcohol effects. 1984;Plenum Press, New York.
4. Bond N., DiGiusto E. Effects of prenatal alcohol consumption in open field behavior and alcohol preference in rats. Psychopharmacology (Berlin). 46:1976;163-165.
5. Bonthius D.J., Bonthius N.E., Napper R.M., West J.R. Early postnatal alcohol exposure acutely and permanently reduces the number of granule cells and mitral cells in the rat olfactory bulb. A stereological study J. Comp. Neurol. 324:1992;557-566.
6. Chotro M.G., Molina J.C. Acute ethanol contamination of the amniotic fluid during gestational day 21. Postnatal changes in ethanol responsiveness in rats Dev. Psychobiol. 23:1990;535-547.
7. Chotro M.G., Córdoba N.E., Molina J.C. Acute prenatal experience with ethanol in the amniotic fluid. Interactions with aversive and appetitive ethanol orosensory learning in the rat pup Dev. Psychobiol. 24:1991;431-451.
8. Chotro M.G., Molina J.C. Bradycardiac responses elicited by ethanol odor in rat neonates. Influence of in utero experience with ethanol Psychopharmacology (Berlin). 106:1992;491-496.
9. Chotro M.G., Spear N.E. Repeated exposure to moderate doses of alcohol in the rat fetus. Evidence of sensitization to toxic and chemosensory aspects of alcohol Alcohol. Clin. Exp. Res. 21:1997;360-367.
10. Di Lorenzo P., Kiefer S., Rice A., García J. Neural and behavioral responsivity to ethyl alcohol as a tastant. Brain Res. Bull. 3:1986;55-61.
11. Domínguez H.D., Chotro M.G., Molina J.C. Alcohol in the amniotic fluid prior to cesarean delivery. Effects of subsequent exposure to the drug's odor upon alcohol responsiveness Behav. Neural Biol. 60:1993;129-138.
12. Domínguez H.D., López M.F., Chotro M.G., Molina J.C. Perinatal responsiveness to alcohol's chemosensory cues as a function of prenatal alcohol administration during gestational days 17-20 in the rat. Neurobiol. Learn. Memory. 65:1996;103-112.
13. Domínguez, H. D.; López, M. F.; Molina, J. C.: Alcohol as aversive or appetitive reinforcer in rat pups prenatally exposed to the drug during late gestation. Paper presented at 1995 Research Society on Alcoholism Meeting, Steamboat Springs, CO, June 17-22, 1995.
14. Hall W.G. The ontogeny of ingestive behavior. Changing control of components in the feeding sequence. Stricker E.M. Handbook of behavioral neurology. Food and water intake:1990;77-123 Plenum Press, New York.
15. Hayashi T., Tadokoro S. Learning retardation and enhanced ethanol preference produced by postnatal pretreatments with ethanol in adult rats. Jpn. J. Pharmacol. 37:1985;269-276.
16. Hunt P.S., Molina J.C., Rajachandran L., Spear L.P., Spear N.E. Chronic administration of alcohol in the developing rat. Expression of functional tolerance and alcohol olfactory aversions Behav. Neural Biol. 59:1993;87-99.
17. Kelly S.J., Bonthius B.S., West J.R. Developmental changes in alcohol pharmacokinetics in rats. Alcohol. Clin. Exp. Res. 3:1987;281-286.
18. Kiefer C.W., Mahadevan R.S. The taste of alcohol for rats as revealed by aversion generalization test. Chem. Senses. 18:1993;509-522.
19. Kiefer S.W., Morrow N.S., Metzler C.W. Alcohol aversion generalization in rats. Specific disruption of taste and odor cues with gustatory neocortex or olfactory bulb ablations Behav. Neurosci. 102:1988;733-739.
20. Kraebel, K. S.; McKinzie, D.; Chotro, M. G.; Wurtzel, N.; Molina, J. C.; Spear, N. E.: Chronic prenatal exposure to ethanol influences later responsivity to chemosensory cues of ethanol in infant rat pups. Paper presented at meetings of the International Society for Developmental Psychobiology, Alexandria, VA, November, 1993.
21. Molina J.C., Chotro M.G. Acute alcohol intoxication paired with appetitive reinforcement. Effects upon ethanol intake in infant rats Behav. Neural Biol. 51:1989;326-345.
22. Molina J.C., Chotro M.G. Acute alcohol intoxication paired with aversive reinforcement. Ethanol odor as a conditioned reinforcer in rat pups Behav. Neural Biol. 52:1989;1-19.
23. Molina J.C., Chotro M.G. Association between chemosensory stimuli and cesarean delivery in rat fetuses. Neonatal presentation of similar stimuli increases motor activity Behav. Neural Biol. 55:1991;42-60.
24. Molina J.C., Bannoura M.D., Chotro M.G., McKinzie D.L., Moore A., Spear N.E. Alcohol mediated tactile conditioned aversions in infant rats. Devaluation of conditioning through alcohol-sucrose associations Neurobiol. Learn. Memory. 66(2):1996;121-132.
25. Molina J.C., Chotro M.G., Spear N.E. Early (preweanling) recognition of ethanol's orosensory cues resulting from acute ethanol intoxication. Behav. Neural Biol. 51:1989;307-325.
26. Molina J.C., Moyano H., Spear L.P., Spear N.E. Acute alcohol exposure during gestational day 8 in the rat. Effects upon physical and behavioral parameters Alcohol. 1:1984;459-464.
27. Molina J.C., Serwatka J., Spear N.E. Changes in alcohol intake resulting from prior experiences with alcohol odor in young rats. Pharmacol. Biochem. Behav. 21:1984;387-391.
28. Molina J.C., Serwatka J., Hoffmann H., Spear N.E. Establishing intermodal equivalence in preweanling and adult rats. J. Exp. Psychol. Anim. Behav. Proc. 17:1991;433-447.
29. Pedersen P.E., Blass E.M. Olfactory control over suckling in albino rats. Aslin R.N., Alberts J.R., Petersen M.R. The development of perception. Psychobiological processes:1981;359-381 Lawrence Erlbaum Associates, Hillsdale, NJ.
30. Pedersen P.E., Blass E.M. Prenatal and postnatal determinants of the first suckling episode in albino rats. Dev. Psychobiol. 15:1982;349-355.
31. Pedersen P.E., Stewart W.B., Greer C.A., Shepherd G.M. Evidence for olfactory function in utero. Science. 221:1983;478-480.
32. Rhinehart-Doty J.A., Schumm J., Smith J.C., Smith G.P. A nontaste cue of sucrose in short-term taste test in rats. Chem. Senses. 19:1994;425-431.
33. Shepherd G.M., Pedersen P.E., Greer C.A. Development of olfactory specificity in the albino rat. A model system Krasnegor N.A., Blass E.M., Hofer M.A., Smotherman W.P. Perinatal development. A psychobiological perspective:1987;127-144 Academic Press, Orlando.
34. Smotherman W.P., Robinson S.R. Behavior of rat fetuses following chemical or tactile stimulation. Behav. Neurosci. 102:1988;24-34.
35. Smotherman W.P., Robinson S.R. Environmental determinants of behavior in the rat fetus. Anim. Behav. 34:1986;1859-1873.
36. Smotherman W.P., Robinson S.R. Psychobiology of fetal experience in the rat. Krasnegor N.A., Blass E.M., Hofer M.A., Smotherman W.P. Perinatal development. A psychobiological perspective:1987;39-60 Academic Press, Orlando.
37. Smotherman W.P., Robinson S.R. Rat fetuses respond to chemical stimuli in gas phase. Physiol. Behav. 47:1990;863-868.
38. Smotherman W.P., Robinson S.R. The prenatal origins of behavioral organization. Psychol. Sci. 1:1990;97-106.
39. Smotherman W.P., Robinson S.R. The rat fetus in its environment. Behavioral adjustments to novel, familiar, aversive and conditioned stimuli presented in utero Behav. Neurosci. 99:1985;521-530.
40. Smotherman W.P. Odor aversion learning by the rat fetus. Physiol. Behav. 29:1982;769-771.
41. Smotherman W.P., Robinson S.R., Ronca A.E., Alberts J., Hepper P.G. Heart rate responses of the rat fetus and neonate to a chemosensory stimulus. Physiol. Behav. 50:1991;47-52.
42. Spear L.P., Spetch S.M., Kirstein C.L., Kuhn C.M. Anterior and posterior, but not cheek, intraoral cannulation procedures elevate serum corticosterone levels in neonatal rat pups. Dev. Psychobiol. 22:1989;401-412.
43. Spear N.E., Molina J.C. The role of sensory modality in the ontogeny of stimulus selection. Krasnegor N.A., Blass E.M., Hofer M.A., Smotherman W.P. Perinatal development. A psychobiological perspective:1987;85-109 Academic Press, Orlando.
44. Stickrod G., Kimble D.P., Smotherman W.P. In utero taste/odor aversion conditioning in the rat. Physiol. Behav. 28:1982;5-7.
45. Szeto H.H. Maternal-fetal pharmacokinetics and fetal dose-response relationships. Ann. NY Acad. Sci. 562:1989;42-55.
46. Teicher M., Blass E. First suckling response of the newborn rat. The roles of olfaction and amniotic fluid Science. 198:1977;635-636.
47. Varendi H., Porter R.H., Winberg J. Attractiveness of amniotic fluid. Evidence of prenatal olfactory learning? Acta Paediatr. 85:1996;1223-1227.