Bimodal effects of the K v7 channel activator retigabine on vascular K + currents

British Journal of Pharmacology

Volumn 155, Issue 1, 2008, Pages 62-72

  Yeung, S Y M ^a   Schwake, M ^b   Pucovsky V ^c   Greenwood, I A ^a  

^a ST GEORGE'S UNIVERSITY OF LONDON   (United Kingdom)

^b UNIVERSITY OF KIEL   (Germany)

^c QUEEN'S UNIVERSITY BELFAST   (United Kingdom)

Author keywords

Immunocytochemistry; Isometric tension; K v7; KCNQ; Retigabine; RT PCR; Vascular smooth muscle; XE991

Indexed keywords

10,10 BIS(4 PYRIDINYLMETHYL) 9(10H) ANTHRACENONE; FLUPIRTINE; KV7 POTASSIUM CHANNEL; POTASSIUM CHANNEL BLOCKING AGENT; POTASSIUM CHANNEL KCNQ; POTASSIUM ION; RETIGABINE; RNA; UNCLASSIFIED DRUG; VOLTAGE GATED POTASSIUM CHANNEL; 10,10-BIS(4-PYRIDINYLMETHYL)-9(10H)-ANTHRACENONE; AMINOPYRIDINE DERIVATIVE; ANTHRACENE DERIVATIVE; CARBAMIC ACID DERIVATIVE; KCNQ1 PROTEIN, MOUSE; KCNQ4 PROTEIN, MOUSE; KCNQ5 CHANNEL, MOUSE; MESSENGER RNA; PHENYLENEDIAMINE DERIVATIVE; POTASSIUM; POTASSIUM CHANNEL KCNQ1; RECOMBINANT PROTEIN; VASODILATOR AGENT;

ANIMAL TISSUE; ARTICLE; CONFOCAL MICROSCOPY; CONTROLLED STUDY; DRUG TARGETING; GENE EXPRESSION; IMMUNOCYTOCHEMISTRY; MEMBRANE POTENTIAL; MOUSE; MUSCLE CELL; NONHUMAN; OOCYTE; PORTAL VEIN; POTASSIUM CURRENT; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; VASCULAR SMOOTH MUSCLE; VOLTAGE CLAMP; XENOPUS; ANIMAL; BAGG ALBINO MOUSE; CELL MEMBRANE POTENTIAL; DOSE RESPONSE; DRUG EFFECT; DRUG POTENTIATION; GENETICS; IN VITRO STUDY; METABOLISM; SMOOTH MUSCLE FIBER; TIME; VASOCONSTRICTION; XENOPUS LAEVIS;

AMINOPYRIDINES; ANIMALS; ANTHRACENES; CARBAMATES; DOSE-RESPONSE RELATIONSHIP, DRUG; KCNQ POTASSIUM CHANNELS; KCNQ1 POTASSIUM CHANNEL; MEMBRANE POTENTIALS; MICE; MICE, INBRED BALB C; MUSCLE, SMOOTH, VASCULAR; MYOCYTES, SMOOTH MUSCLE; PHENYLENEDIAMINES; PORTAL VEIN; POTASSIUM; POTASSIUM CHANNEL BLOCKERS; RECOMBINANT PROTEINS; RNA, MESSENGER; TIME FACTORS; VASOCONSTRICTION; VASODILATOR AGENTS; XENOPUS LAEVIS;

EID: 50249146243     PISSN: 00071188     EISSN: 14765381     Source Type: Journal    
DOI: 10.1038/bjp.2008.231     Document Type: Article

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