Adhesion molecules - Their role in health and disease

Pediatric Research

Volumn 39, Issue 2, 1996, Pages 191-198

  Etzioni, Amos ^a,b  

^a TECHNION ISRAEL INSTITUTE OF TECHNOLOGY   (Israel)

^b RAMBAM MEDICAL CENTER   (Israel)

Author keywords

[No Author keywords available]

Indexed keywords

ENDOTHELIAL LEUKOCYTE ADHESION MOLECULE 1; INTEGRIN; INTERCELLULAR ADHESION MOLECULE 1; L SELECTIN; PADGEM PROTEIN; TUMOR NECROSIS FACTOR; VASCULAR CELL ADHESION MOLECULE 1;

INFLAMMATION; LEUKOCYTE ACTIVATION; LEUKOCYTE ADHESION DEFICIENCY; LEUKOCYTE MIGRATION; LEUKOCYTOSIS; PRIORITY JOURNAL; RECURRENT INFECTION; REVIEW; WOUND HEALING;

EID: 0030045497     PISSN: 00313998     EISSN: None     Source Type: Journal    
DOI: 10.1203/00006450-199602000-00001     Document Type: Review

References (59)

1. Carlos TM, Harlan JM 1994 Leukocyte endothelial adhesion molecules. Blood 84:2068-2101
2. Springer TA 1994 Traffic signals for lymphocyte recruitment and leukocyte emigration: the multistep paradigm. Cell 76:301-314
3. Hynes RO 1992 Integrins: versatility, modulation, and signaling in cell adhesion. Cell 69:11-25
4. Smyth SS, Joneckis CC, Parise LV 1993 Regulation of vascular integrins. Blood 81:2827-2843
5. Hibbs ML, Xu H, Stacker SA, Springer TA 1991 Regulation of the adhesion of ICAM-1 by the cytoplasmic domain of LFA-1 integrin β subunit. Science 251:1611-1613
6. Springer TA, Thompson NS, Miller LJ, Schmalsstieg FC, Anderson DC 1984 Inherited deficiency of the MAC-1, LFA-1,p150,95 glycoprotein family and its molecular basis. J Exp Med 160:1901-1918
7. Kishimoto TK, Rothlein R 1993 Adhesion molecules which guide neutrophil endothelial cell interaction at site of inflammation. In: Gupta S, Griscelli C (eds) New Concepts in Immunodeficiency Diseases. John Wiley & Sons, New-York, pp 131-152
8. Dustin ML, Springer TA 1988 Lymphocyte function associate antigen-1 (LFA-1) interaction with intecellular adhesion molecule-1 (ICAM-1) is one of at least three mechanisms for lymphocyte adhesion to culture endothelial cell J Cell Biol 107:321-331
9. 4 integrins in vivo. J Clin Invest 94:1722-1728
10. Diamond MS, Staunton DE, Marlin SD, Springer TA 1991 Binding of the integrin MAC-1 (CD11b/CD18) to the third immunoglobulin like domain of ICAM-1 (CD54) and its regulation by glycosylation. Cell 65:961-971
11. Staunton DE, Dustin ML, Springer TA 1989 Functional cloning of ICAM-2, a cell adhesion ligand for LFA-1 homologous to ICAM-1. Nature 339:61-64
12. de Fougerolles AR, Springer TA 1992 Intracellular adhesion molecule 3, a third adhesion counter-receptor for lymphocyte function associated molecule 1 on resting lymphocytes. J Exp Med 175:185-190
13. Etzioni A 1994 Adhesion molecules in host defense. Clin Diagn Lab Immunol 1:1-4
14. Campanero MR, Sanchez-Matios P, del Pozo MA, Sanchez-Madrid F 1994 ICAM-3 regulates lymphocyte morphology and integrin mediated T cell interaction with endothelial cell and extracellular matrix ligands. J Cell Biol 127:867-878
15. Gearing AJH, Newman W 1993 Circulating adhesion molecules in disease. Immunol Today 14:506-512
16. Pepinsky B, Hession C, Chen LL, Moy P, Burkly L, Jakubowski A, Show EP, Benjamin C 1992 Structure/function studies in vascular cell adhesion molecule-1. J Biol Chem 267:17820-17826
17. Bevilacqua MP 1993 Endothelial leukocyte adhesion molecules. Annu Rev Immunol 11:767-804
18. Bevilacqua MP, Nelson RM 1993 Selectins. J Clin Invest 91:379-387
19. Cotran RS, Gimbrone MA, Bevilacqua PM, Mendrick DL, Pober JS 1986 Induction and detection of a human endothelial activation antigens in vivo.J Exp Med 164:661-666
20. Gotsch U, Jager U, Dominis M, Vestweber D 1994 Expression of P-selectin on endothelial cells is upregulated by LPS and TNF-α in vivo. Cell Adhes Commun 2:7-14
21. Jung TM, Dailey MO 1990 Rapid modulation of homing receptors (gp90 mel-14) induced by activators of protein kinase C: receptor shedding due to accelerated proteolytic cleavage at the cell surface. J Immunol 144:3130-3136
22. Schleiffenbaum B, Spertini O, Tedder TF 1992 Soluble L-selectin is present in human plasma at high levels and retains functional activity. J Cell Biol 119:229-238
23. Varki A 1994 Selectin ligands. Proc Natl Acad Sci USA 91:7390-7397
24. Butcher EC 1991 Leukocyte-endothelial cell recognition: three (or more) steps to specificity and diversity. Cell 67:1033-1036
25. Lawrence MB, Springer TA 1991 Leukocyte roll on a selectin at physiologic flow rates: distinction from and prerequisite for adhesion through integrins. Cell 65:859-873
26. 2 integrins in vivo. Proc Natl Acad Sci USA 88:7538-7542
27. Olofsson AM, Arfors KE, Ramezani L, Wolitzky BA, Butcher EC, von Andrian UH 1994 E-selectin mediated leukocyte rolling in interleukin-1 treated rabbit mesentery venules. Blood 84:2749-2758
28. Mayadas TN, Johnson RC, Raybum H, Hynes RO, Wagner DD 1993 Leukocyte rolling and extravasation are severely compromised in P-selectin deficient mice. Cell 74:541-554
29. von Andrian UH, Berger EM, Ramezani L, Chambers JD, Ochs HD, Harlan JM, Paulson JC, Etzioni A, Arfors KE 1993 In vivo behavior of neutrophils from two patients with distinct inherited leukocyte adhesion deficiency syndromes. J Clin Invest 91:2893-2897
30. DeGraaf TW, Von der Stelt ME, Anbergen MG, van Dijk W 1993 Inflammation induced expression of sialyl Lewis X containing glycan structures on A acid glycoprotein (oromucid) in human sera. J Exp Med 177:657-666
31. Zimmerman GA, Prescott SM, McIntyre TM 1992 Endothelial cell interactions with granulocytes: tethering and signaling molecules. Immunol Today 13:93-100
32. Muller WA, Weigl SA, Deng X, Phillips DM 1993 PECAM-1 is required for transendothelial migration of leukocytes. J Exp Med 178:449-457
33. Shuster DE, Kehrli ME, Ackermann MR, Gilbert RO 1992 Identification and prevalence of a genetic defect that causes leukocyte adhesion deficiency in Holstein cattle. Proc Natl Acad Sci USA 89:9225-9229
34. Wilson RW, Ballantyne CM, Smith CW, Montgomery C, Bradley A, O'Brien WE, Beaudet AL 1993 Gene targeting yields a CD18 mutant mouse for study of inflammation. J Immunol 151:1571-1578
35. Sligh JE, Ballantyne CM, Rich SS, Hawkins HK, Smith CW, Bradley A, Beaudet AL 1993 Inflammatory and immune responses are impaired in mice deficient in intercellular adhesion molecule 1. Proc Natl Acad Sci USA 90:8529-8533
36. Xu H, Gonzalo JA, St. Pierre Y, Williams IR, Kupper TS, Cortan RS, Springer TA, Gutierrez-Ramos JC 1994 Leukocytosis and resistance to septic shock in intercellular adhesion molecule-1 deficient mice. J Exp Med 180:95-109
37. Labow MA, Norton CR, Rumberger JM, Lombard-Gillooly KM, Shuster DJ, Hubband J, Bertko R, Knaas PA, Terry RW, Harbison ML, Kontgen F, Stewart CL, McIntyre KM, Will PC, Burns DK, Wolitzky BA 1994 Characterization of E-selectin deficient mice: demonstration of overlapping function of the endothelial selectins. Immunity 1:709-720
38. Arbones ML, Ord DC, Ley K, Ratech H, Maynard-Curry C, Otten G, Capon DJ, Tedder TF 1994 Lymphocyte homing and leukocyte rolling and migration are impaired in L-selectin deficient mice. Immunity 1:247-260
39. Etzioni A 1994 Adhesion molecule deficiencies and their clinical significance. Cell Adhes Commun 2:257-260
40. Harlan JM 1993 Leukocyte adhesion deficiency syndrome: insights into the molecular basis of leukocyte emigration. Clin Immunol Immunopathol 67:s16-s24
41. Sligh JE, Hurwittz MY, Zhu C, Anderson DC, Beauder AL 1992 An initiation codon mutation in CD18 in association with the moderate phenotype of leukocyte adhesion deficiency. J Biol Chem 267:714-718
42. Schwartz BR, Harlan JM 1991 Consequence of deficient granulocyte endothelium interaction. In: Gordon JL (ed) Vascular Endothelium Interactions with Circulating Cells. Elsevier Science Publishers B.V., Amsterdam, pp 231-252
43. Anderson DC, Springer TA 1987 Leukocyte adhesion deficiency: an inherited defect in the Mac-1, LFA-1, and p150,95 glycoproteins. Annu Rev Med 38:175-194
44. Fisher A, Lisowska-Grospierre B, Anderson DC, Springer TA 1988 Leukocyte adhesion deficiency: molecular basis and functional consequences. Immunodefic Rev 1:39-54
45. Wilson JM, Ping AJ, Krauss JC, Mayo-Bond L, Rogers CE, Anderson DC, Todd RF 1990 Correction of CD18-deficient lymphocytes by retrovirus mediated gene transfer. Science 248:1413-1416
46. Etzioni A, Frydman M, Pollack S, Avidor I, Phillips ML, Pualsom JC, Gershoni-Baruch R 1992 Severe recurrent infections due to a novel adhesion molecule defect. N Engl J Med 327:1789-1792
47. Etzioni A, Harlan JM, Pollack S, Phillips LM, Gershoni-Baruch R, Paulson JC 1993 Leukocyte adhesion deficiency (LAD) II: a new adhesion defect due to absence of sialyl Lewis X, the ligand for selectins. Immunodeficiency 4:307-308
48. Etzioni A, Phillips LM, Paulson JV[undot]iC, Harlan JM 1995 Leukocyte adhesion deficiency (LAD) II. In: Cell Adhesion and Human Disease (Ciba Foundation Symposium 189). Wiley, Chichester, UK, pp 51-62
49. Price TH, Ochs HD, Gershoni-Baruch R, Harlan JM, Etzioni A 1994 In vivo neutrophil and lymphocyte function studies in a patient with leukocyte adhesion deficiency type II. Blood 84:1635-1639
50. Adams DH, Shaw S 1994 Leukocyte endothelial interactions and regulation of leukocyte migration. Lancet 343:831-836
51. Bevilacqua MP, Nelson RM, Mannori G, Cecconi O 1994 Endothelial leukocyte adhesion molecules in human disease. Annu Rev Med 45:361-378
52. Albelda SM, Smith CW, Ward PA 1994 Adhesion molecules and inflammatory injury. FASEB J 8:504-512
53. Mihelcic D, Schleiffenbaum B, Tedder TF, Sharar SR, Harlan JM, Winn RK 1994 Inhibition of leukocyte L-selectin function with a monoclonal antibody attenuates reperfusion injury to the rabbit ear. Blood 84:2322-2328
54. Bochner BS, Schleimer RP 1994 Role of adhesion molecules in human eosinophil and basophil recruitment. J Allergy Clin Immunol 94:427-438
55. Burkly LC, Jakubowski A, Hattori M 1994 Protection against adaptive transfer of autoimmune diabetes mediated through very late antigen-4 integrin. Diabetes 43:529-534
56. Granert C, Raud J, Xie X, Lindquist L, Lindbom L 1994 Inhibition of leukocyte rolling with polysaccharide fucoidin prevents pleocytosis in experimental meningitis in the rabbit. J Clin Invest 93:929-936
57. Haug CE, Colvin RB, Delmonico FL, Auchincloss H Jr, Tolkoff-Rubin N, Prteffer FI, Rothlein R, Norris S, Scharschmidt L, Cosimi AB 1993 A phase I trail of immunosuppression with anti ICAM-1 (CD54) mAb in renal allograft recipients. Transplantation 55:766-773
58. Gorski A 1994 The role of cell adhesion molecules in immunopathology. Immunol Today 15:251-255
59. Phillips LM, Schwartz BR, Etzioni A, Boyer R, Ochs HD, Paulson JC, Harlan JM 1995 Neutrophil adhesion in leukocyte adhesion deficiency syndrome type II (LAD II). J Clin Invest (in press)