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Volumn 26, Issue 38, 2008, Pages 4918-4926

Anti-EGFR activation, anti-proliferative and pro-apoptotic effects of polyclonal antibodies induced by EGFR-based cancer vaccine

Author keywords

Cancer; Polyclonal antibodies; Vaccine

Indexed keywords

ADJUVANT; CANCER VACCINE; CETUXIMAB; EPIDERMAL GROWTH FACTOR RECEPTOR; EPIDERMAL GROWTH FACTOR RECEPTOR ANTIBODY; POLYCLONAL ANTIBODY;

EID: 50249128651     PISSN: 0264410X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.vaccine.2008.07.018     Document Type: Article
Times cited : (26)

References (51)
  • 1
    • 0034614637 scopus 로고    scopus 로고
    • The hallmarks of cancer
    • Hanahan D., and Weinberg R.A. The hallmarks of cancer. Cell 100 1 (2000) 57-70
    • (2000) Cell , vol.100 , Issue.1 , pp. 57-70
    • Hanahan, D.1    Weinberg, R.A.2
  • 2
    • 0021134481 scopus 로고
    • Human squamous cell lung cancers express increased epidermal growth factor receptors
    • Hendler F.J., and Ozanne B.W. Human squamous cell lung cancers express increased epidermal growth factor receptors. J Clin Invest 74 2 (1984) 647-651
    • (1984) J Clin Invest , vol.74 , Issue.2 , pp. 647-651
    • Hendler, F.J.1    Ozanne, B.W.2
  • 3
    • 0021226547 scopus 로고
    • Epidermal growth factor receptors in human breast cancer
    • Perez R., Pascual M., Macias A., and Lage A. Epidermal growth factor receptors in human breast cancer. Breast Cancer Res Treat 4 3 (1984) 189-193
    • (1984) Breast Cancer Res Treat , vol.4 , Issue.3 , pp. 189-193
    • Perez, R.1    Pascual, M.2    Macias, A.3    Lage, A.4
  • 4
    • 0022656554 scopus 로고
    • Expression of epidermal growth factor receptors on human cervical, ovarian, and vulval carcinomas
    • Gullick W.J., Marsden J.J., Whittle N., Ward B., Bobrow L., and Waterfield M.D. Expression of epidermal growth factor receptors on human cervical, ovarian, and vulval carcinomas. Cancer Res 46 1 (1986) 285-292
    • (1986) Cancer Res , vol.46 , Issue.1 , pp. 285-292
    • Gullick, W.J.1    Marsden, J.J.2    Whittle, N.3    Ward, B.4    Bobrow, L.5    Waterfield, M.D.6
  • 5
    • 13844250537 scopus 로고    scopus 로고
    • The epidermal growth factor receptor as a target for colorectal cancer therapy
    • Lockhart C., and Berlin J.D. The epidermal growth factor receptor as a target for colorectal cancer therapy. Semin Oncol 32 1 (2005) 52-60
    • (2005) Semin Oncol , vol.32 , Issue.1 , pp. 52-60
    • Lockhart, C.1    Berlin, J.D.2
  • 6
    • 0027359459 scopus 로고
    • Expression of epidermal growth factor receptor and survival in upper aerodigestive tract cancer
    • Dassonville O., Formento J.L., Francoual M., Ramaioli A., Santini J., Schneider M., et al. Expression of epidermal growth factor receptor and survival in upper aerodigestive tract cancer. J Clin Oncol 11 10 (1993) 1873-1878
    • (1993) J Clin Oncol , vol.11 , Issue.10 , pp. 1873-1878
    • Dassonville, O.1    Formento, J.L.2    Francoual, M.3    Ramaioli, A.4    Santini, J.5    Schneider, M.6
  • 8
    • 0027140978 scopus 로고
    • Androgens regulate proliferation of human prostate cancer cells in culture by increasing transforming growth factor-alpha (TGF-alpha) and epidermal growth factor (EGF)/TGF-alpha receptor
    • Liu X.H., Wiley H.S., and Meikle A.W. Androgens regulate proliferation of human prostate cancer cells in culture by increasing transforming growth factor-alpha (TGF-alpha) and epidermal growth factor (EGF)/TGF-alpha receptor. J Clin Endocrinol Metab 77 6 (1993) 1472-1478
    • (1993) J Clin Endocrinol Metab , vol.77 , Issue.6 , pp. 1472-1478
    • Liu, X.H.1    Wiley, H.S.2    Meikle, A.W.3
  • 9
    • 84920241849 scopus 로고
    • Epidermal-growth-factor receptors in human bladder cancer: comparison of invasive and superficial tumours
    • Neal D.E., Marsh C., Bennett M.K., Abel P.D., Hall R.R., Sainsbury J.R., et al. Epidermal-growth-factor receptors in human bladder cancer: comparison of invasive and superficial tumours. Lancet 1 8425 (1985) 366-368
    • (1985) Lancet , vol.1 , Issue.8425 , pp. 366-368
    • Neal, D.E.1    Marsh, C.2    Bennett, M.K.3    Abel, P.D.4    Hall, R.R.5    Sainsbury, J.R.6
  • 10
    • 16644381875 scopus 로고    scopus 로고
    • Relationship between activation of epidermal growth factor receptor and cell dissociation in pancreatic cancer
    • Tan X., Egami H., Ishikawa S., Nakagawa M., Ishiko T., Kamohara H., et al. Relationship between activation of epidermal growth factor receptor and cell dissociation in pancreatic cancer. Int J Oncol 25 5 (2004) 1303-1309
    • (2004) Int J Oncol , vol.25 , Issue.5 , pp. 1303-1309
    • Tan, X.1    Egami, H.2    Ishikawa, S.3    Nakagawa, M.4    Ishiko, T.5    Kamohara, H.6
  • 12
    • 0032731892 scopus 로고    scopus 로고
    • Tumor invasion: role of growth factor-induced cell motility
    • Wells A. Tumor invasion: role of growth factor-induced cell motility. Adv Cancer Res 78 (2000) 31-101
    • (2000) Adv Cancer Res , vol.78 , pp. 31-101
    • Wells, A.1
  • 13
    • 0021273420 scopus 로고
    • Human epidermal growth factor receptor cDNA sequence and aberrant expression of the amplified gene in A431 epidermoid carcinoma cells
    • Ullrich A., Coussens L., Hayflick J.S., Dull T.J., Gray A., Tam A.W., et al. Human epidermal growth factor receptor cDNA sequence and aberrant expression of the amplified gene in A431 epidermoid carcinoma cells. Nature 309 5967 (1984) 418-425
    • (1984) Nature , vol.309 , Issue.5967 , pp. 418-425
    • Ullrich, A.1    Coussens, L.2    Hayflick, J.S.3    Dull, T.J.4    Gray, A.5    Tam, A.W.6
  • 15
    • 0016719486 scopus 로고
    • Isolation and structure of urogastrone and its relationship to epidermal growth factor
    • Gregory H. Isolation and structure of urogastrone and its relationship to epidermal growth factor. Nature 257 5524 (1975) 325-327
    • (1975) Nature , vol.257 , Issue.5524 , pp. 325-327
    • Gregory, H.1
  • 16
    • 0025634139 scopus 로고
    • Transforming growth factor-alpha: an oncodevelopmental growth factor
    • Salomon D.S., Kim N., Saeki T., and Ciardiello F. Transforming growth factor-alpha: an oncodevelopmental growth factor. Cancer Cells 2 12 (1990) 389-397
    • (1990) Cancer Cells , vol.2 , Issue.12 , pp. 389-397
    • Salomon, D.S.1    Kim, N.2    Saeki, T.3    Ciardiello, F.4
  • 17
    • 0037291226 scopus 로고    scopus 로고
    • The crystal structure of a truncated ErbB2 ectodomain reveals an active conformation, poised to interact with other ErbB receptors
    • Garrett T.P., McKern N.M., Lou M., Elleman T.C., Adams T.E., Lovrecz G.O., et al. The crystal structure of a truncated ErbB2 ectodomain reveals an active conformation, poised to interact with other ErbB receptors. Mol Cell 11 2 (2003) 495-505
    • (2003) Mol Cell , vol.11 , Issue.2 , pp. 495-505
    • Garrett, T.P.1    McKern, N.M.2    Lou, M.3    Elleman, T.C.4    Adams, T.E.5    Lovrecz, G.O.6
  • 18
    • 0037429728 scopus 로고    scopus 로고
    • Ligand-independent oncogenic signaling by the epidermal growth factor receptor: v-ErbB as a paradigm
    • Boerner J.L., Danielsen A., and Maihle N.J. Ligand-independent oncogenic signaling by the epidermal growth factor receptor: v-ErbB as a paradigm. Exp Cell Res 284 1 (2003) 111-121
    • (2003) Exp Cell Res , vol.284 , Issue.1 , pp. 111-121
    • Boerner, J.L.1    Danielsen, A.2    Maihle, N.J.3
  • 19
    • 0035869407 scopus 로고    scopus 로고
    • Use of chemotherapy plus a monoclonal antibody against HER2 for metastatic breast cancer that overexpresses HER2
    • Slamon D.J., Leyland-Jones B., Shak S., Fuchs H., Paton V., Bajamonde A., et al. Use of chemotherapy plus a monoclonal antibody against HER2 for metastatic breast cancer that overexpresses HER2. N Engl J Med 344 11 (2001) 783-792
    • (2001) N Engl J Med , vol.344 , Issue.11 , pp. 783-792
    • Slamon, D.J.1    Leyland-Jones, B.2    Shak, S.3    Fuchs, H.4    Paton, V.5    Bajamonde, A.6
  • 20
    • 12544259114 scopus 로고    scopus 로고
    • Endogenous anti-HER2 antibodies block HER2 phosphorylation and signaling through extracellular signal-regulated kinase
    • Montgomery R.B., Makary E., Schiffman K., Goodell V., and Disis M.L. Endogenous anti-HER2 antibodies block HER2 phosphorylation and signaling through extracellular signal-regulated kinase. Cancer Res 65 2 (2005) 650-656
    • (2005) Cancer Res , vol.65 , Issue.2 , pp. 650-656
    • Montgomery, R.B.1    Makary, E.2    Schiffman, K.3    Goodell, V.4    Disis, M.L.5
  • 21
    • 0028955388 scopus 로고
    • Epidermal growth factor-related peptides and their receptors in human malignancies
    • Salomon D., Brandt R., Ciardiello F., and Normanno N. Epidermal growth factor-related peptides and their receptors in human malignancies. Crit Rev Oncol Hematol 19 3 (1995) 183-232
    • (1995) Crit Rev Oncol Hematol , vol.19 , Issue.3 , pp. 183-232
    • Salomon, D.1    Brandt, R.2    Ciardiello, F.3    Normanno, N.4
  • 23
    • 2442704412 scopus 로고    scopus 로고
    • Use of the humanized anti-epidermal growth factor receptor monoclonal antibody h-R3 in combination with radiotherapy in the treatment of locally advanced head and neck cancer patients
    • Crombet T., Osorio M., Cruz T., Roca C., del Castillo R., Mon R., et al. Use of the humanized anti-epidermal growth factor receptor monoclonal antibody h-R3 in combination with radiotherapy in the treatment of locally advanced head and neck cancer patients. J Clin Oncol 22 9 (2004) 1646-1654
    • (2004) J Clin Oncol , vol.22 , Issue.9 , pp. 1646-1654
    • Crombet, T.1    Osorio, M.2    Cruz, T.3    Roca, C.4    del Castillo, R.5    Mon, R.6
  • 24
    • 0037443418 scopus 로고    scopus 로고
    • Immunogene therapy of tumors with vaccine based on xenogeneic epidermal growth factor receptor
    • Lu Y., Wei Y.Q., Tian L., Zhao X., Yang L., Hu B., et al. Immunogene therapy of tumors with vaccine based on xenogeneic epidermal growth factor receptor. J Immunol 170 6 (2003) 3162-3170
    • (2003) J Immunol , vol.170 , Issue.6 , pp. 3162-3170
    • Lu, Y.1    Wei, Y.Q.2    Tian, L.3    Zhao, X.4    Yang, L.5    Hu, B.6
  • 25
    • 20944443737 scopus 로고    scopus 로고
    • Active antitumor immunity elicited by vaccine based on recombinant form of epidermal growth factor receptor
    • Hu B., Wei Y., Tian L., Zhao X., Lu Y., Wu Y., et al. Active antitumor immunity elicited by vaccine based on recombinant form of epidermal growth factor receptor. J Immunother 28 3 (2005) 236-244
    • (2005) J Immunother , vol.28 , Issue.3 , pp. 236-244
    • Hu, B.1    Wei, Y.2    Tian, L.3    Zhao, X.4    Lu, Y.5    Wu, Y.6
  • 26
    • 33748861242 scopus 로고    scopus 로고
    • Active antimetastatic immunotherapy in Lewis lung carcinoma with self EGFR extracellular domain protein in VSSP adjuvant
    • Ramirez B.S., Pestana E.S., Hidalgo G.G., Garcia T.H., Rodriguez R.P., Ullrich A., et al. Active antimetastatic immunotherapy in Lewis lung carcinoma with self EGFR extracellular domain protein in VSSP adjuvant. Int J Cancer 119 9 (2006) 2190-2199
    • (2006) Int J Cancer , vol.119 , Issue.9 , pp. 2190-2199
    • Ramirez, B.S.1    Pestana, E.S.2    Hidalgo, G.G.3    Garcia, T.H.4    Rodriguez, R.P.5    Ullrich, A.6
  • 27
    • 33344475049 scopus 로고    scopus 로고
    • Very small size proteoliposomes derived from Neisseria meningitidis: an effective adjuvant for generation of CTL responses to peptide and protein antigens
    • Mesa C., de Leon J., and Fernandez L.E. Very small size proteoliposomes derived from Neisseria meningitidis: an effective adjuvant for generation of CTL responses to peptide and protein antigens. Vaccine 24 14 (2006) 2692-2699
    • (2006) Vaccine , vol.24 , Issue.14 , pp. 2692-2699
    • Mesa, C.1    de Leon, J.2    Fernandez, L.E.3
  • 28
    • 3843071048 scopus 로고    scopus 로고
    • Very small size proteoliposomes derived from Neisseria meningitidis: an effective adjuvant for Th1 induction and dendritic cell activation
    • Mesa C., De Leon J., Rigley K., and Fernandez L.E. Very small size proteoliposomes derived from Neisseria meningitidis: an effective adjuvant for Th1 induction and dendritic cell activation. Vaccine 22 23-24 (2004) 3045-3052
    • (2004) Vaccine , vol.22 , Issue.23-24 , pp. 3045-3052
    • Mesa, C.1    De Leon, J.2    Rigley, K.3    Fernandez, L.E.4
  • 29
    • 0022006760 scopus 로고
    • Establishment and identification of small cell lung cancer cell lines having classic and variant features
    • Carney D.N., Gazdar A.F., Bepler G., Guccion J.G., Marangos P.J., Moody T.W., et al. Establishment and identification of small cell lung cancer cell lines having classic and variant features. Cancer Res 45 6 (1985) 2913-2923
    • (1985) Cancer Res , vol.45 , Issue.6 , pp. 2913-2923
    • Carney, D.N.1    Gazdar, A.F.2    Bepler, G.3    Guccion, J.G.4    Marangos, P.J.5    Moody, T.W.6
  • 30
    • 0021824123 scopus 로고
    • Establishment and characterization of cell lines from human small cell and large cell carcinomas of the lung
    • Bergh J., Nilsson K., Ekman R., and Giovanella B. Establishment and characterization of cell lines from human small cell and large cell carcinomas of the lung. Acta Pathol Microbiol Immunol Scand A 93 3 (1985) 133-147
    • (1985) Acta Pathol Microbiol Immunol Scand A , vol.93 , Issue.3 , pp. 133-147
    • Bergh, J.1    Nilsson, K.2    Ekman, R.3    Giovanella, B.4
  • 31
    • 0033588519 scopus 로고    scopus 로고
    • Enhancement of the immune response to poorly immunogenic gangliosides after incorporation into very small size proteoliposomes (VSSP)
    • Estevez F., Carr A., Solorzano L., Valiente O., Mesa C., Barroso O., et al. Enhancement of the immune response to poorly immunogenic gangliosides after incorporation into very small size proteoliposomes (VSSP). Vaccine 18 1-2 (1999) 190-197
    • (1999) Vaccine , vol.18 , Issue.1-2 , pp. 190-197
    • Estevez, F.1    Carr, A.2    Solorzano, L.3    Valiente, O.4    Mesa, C.5    Barroso, O.6
  • 32
    • 0021061819 scopus 로고
    • Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays
    • Mosmann T. Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays. J Immunol Methods 65 1-2 (1983) 55-63
    • (1983) J Immunol Methods , vol.65 , Issue.1-2 , pp. 55-63
    • Mosmann, T.1
  • 33
    • 0035178569 scopus 로고    scopus 로고
    • Supra-additive cytotoxic effects of a combination of cytostatic drugs and antibody-induced complement activation on tumor cells in vitro
    • Brezicka T., and Einbeigi Z. Supra-additive cytotoxic effects of a combination of cytostatic drugs and antibody-induced complement activation on tumor cells in vitro. Tumour Biol 22 2 (2001) 97-103
    • (2001) Tumour Biol , vol.22 , Issue.2 , pp. 97-103
    • Brezicka, T.1    Einbeigi, Z.2
  • 34
    • 0029670540 scopus 로고    scopus 로고
    • Induction of TH1 and TH2 immunity in neonatal mice
    • Forsthuber T., Yip H.C., and Lehmann P.V. Induction of TH1 and TH2 immunity in neonatal mice. Science 271 5256 (1996) 1728-1730
    • (1996) Science , vol.271 , Issue.5256 , pp. 1728-1730
    • Forsthuber, T.1    Yip, H.C.2    Lehmann, P.V.3
  • 35
    • 0000470849 scopus 로고    scopus 로고
    • Growth inhibition of human lung adenocarcinoma cells by antibodies against epidermal growth factor receptor and by ganglioside GM3: involvement of receptor-directed protein tyrosine phosphatase(s)
    • Suarez Pestana E., Greiser U., Sanchez B., Fernandez L.E., Lage A., Perez R., et al. Growth inhibition of human lung adenocarcinoma cells by antibodies against epidermal growth factor receptor and by ganglioside GM3: involvement of receptor-directed protein tyrosine phosphatase(s). Br J Cancer 75 2 (1997) 213-220
    • (1997) Br J Cancer , vol.75 , Issue.2 , pp. 213-220
    • Suarez Pestana, E.1    Greiser, U.2    Sanchez, B.3    Fernandez, L.E.4    Lage, A.5    Perez, R.6
  • 36
    • 0018726623 scopus 로고
    • Identification of epidermal growth factor receptors in a hyperproducing human epidermoid carcinoma cell line
    • Wrann M.M., and Fox C.F. Identification of epidermal growth factor receptors in a hyperproducing human epidermoid carcinoma cell line. J Biol Chem 254 17 (1979) 8083-8086
    • (1979) J Biol Chem , vol.254 , Issue.17 , pp. 8083-8086
    • Wrann, M.M.1    Fox, C.F.2
  • 37
    • 34250205633 scopus 로고    scopus 로고
    • Further characterization of the epidermal growth factor receptor ligand 11C-PD153035
    • Wang H., Yu J., Yang G.R., Song X.R., Sun X.R., Zhao S.Q., et al. Further characterization of the epidermal growth factor receptor ligand 11C-PD153035. Chin Med J 120 11 (2007) 960-964
    • (2007) Chin Med J , vol.120 , Issue.11 , pp. 960-964
    • Wang, H.1    Yu, J.2    Yang, G.R.3    Song, X.R.4    Sun, X.R.5    Zhao, S.Q.6
  • 38
    • 17444403242 scopus 로고    scopus 로고
    • Structural basis for inhibition of the epidermal growth factor receptor by cetuximab
    • Li S., Schmitz K.R., Jeffrey P.D., Wiltzius J.J., Kussie P., and Ferguson K.M. Structural basis for inhibition of the epidermal growth factor receptor by cetuximab. Cancer Cell 7 4 (2005) 301-311
    • (2005) Cancer Cell , vol.7 , Issue.4 , pp. 301-311
    • Li, S.1    Schmitz, K.R.2    Jeffrey, P.D.3    Wiltzius, J.J.4    Kussie, P.5    Ferguson, K.M.6
  • 39
    • 0034708826 scopus 로고    scopus 로고
    • Cross-talk between epidermal growth factor receptor and c-Met signal pathways in transformed cells
    • Jo M., Stolz D.B., Esplen J.E., Dorko K., Michalopoulos G.K., and Strom S.C. Cross-talk between epidermal growth factor receptor and c-Met signal pathways in transformed cells. J Biol Chem 275 12 (2000) 8806-8811
    • (2000) J Biol Chem , vol.275 , Issue.12 , pp. 8806-8811
    • Jo, M.1    Stolz, D.B.2    Esplen, J.E.3    Dorko, K.4    Michalopoulos, G.K.5    Strom, S.C.6
  • 40
    • 1342323632 scopus 로고    scopus 로고
    • ErbB receptors: directing key signaling networks throughout life
    • Holbro T., and Hynes N.E. ErbB receptors: directing key signaling networks throughout life. Annu Rev Pharmacol Toxicol 44 (2004) 195-217
    • (2004) Annu Rev Pharmacol Toxicol , vol.44 , pp. 195-217
    • Holbro, T.1    Hynes, N.E.2
  • 41
    • 45249086561 scopus 로고    scopus 로고
    • Cetuximab plus oxaliplatin-based chemotherapy in the treatment of colorectal cancer
    • Moosmann N., and Heinemann V. Cetuximab plus oxaliplatin-based chemotherapy in the treatment of colorectal cancer. Expert Rev Anticancer Ther 8 3 (2008) 319-329
    • (2008) Expert Rev Anticancer Ther , vol.8 , Issue.3 , pp. 319-329
    • Moosmann, N.1    Heinemann, V.2
  • 42
    • 33646434844 scopus 로고    scopus 로고
    • Treatment of high-grade glioma patients with the humanized anti-epidermal growth factor receptor (EGFR) antibody h-R3: report from a phase I/II trial
    • Ramos T.C., Figueredo J., Catala M., Gonzalez S., Selva J.C., Cruz T.M., et al. Treatment of high-grade glioma patients with the humanized anti-epidermal growth factor receptor (EGFR) antibody h-R3: report from a phase I/II trial. Cancer Biol Ther 5 4 (2006) 375-379
    • (2006) Cancer Biol Ther , vol.5 , Issue.4 , pp. 375-379
    • Ramos, T.C.1    Figueredo, J.2    Catala, M.3    Gonzalez, S.4    Selva, J.C.5    Cruz, T.M.6
  • 43
    • 34548190981 scopus 로고    scopus 로고
    • T cells are crucial for the anti-metastatic effect of anti-epidermal growth factor receptor antibodies
    • Garrido G., Lorenzano P., Sanchez B., Beausoleil I., Alonso D.F., Perez R., et al. T cells are crucial for the anti-metastatic effect of anti-epidermal growth factor receptor antibodies. Cancer Immunol Immunother 56 11 (2007) 1701-1710
    • (2007) Cancer Immunol Immunother , vol.56 , Issue.11 , pp. 1701-1710
    • Garrido, G.1    Lorenzano, P.2    Sanchez, B.3    Beausoleil, I.4    Alonso, D.F.5    Perez, R.6
  • 44
    • 7444262837 scopus 로고    scopus 로고
    • Active specific immunotherapy of melanoma with a GM3 ganglioside-based vaccine: a report on safety and immunogenicity
    • Guthmann M.D., Bitton R.J., Carnero A.J., Gabri M.R., Cinat G., Koliren L., et al. Active specific immunotherapy of melanoma with a GM3 ganglioside-based vaccine: a report on safety and immunogenicity. J Immunother 27 6 (2004) 442-451
    • (2004) J Immunother , vol.27 , Issue.6 , pp. 442-451
    • Guthmann, M.D.1    Bitton, R.J.2    Carnero, A.J.3    Gabri, M.R.4    Cinat, G.5    Koliren, L.6
  • 45
    • 18644370411 scopus 로고    scopus 로고
    • Crystal structure of a truncated epidermal growth factor receptor extracellular domain bound to transforming growth factor alpha
    • Garrett T.P., McKern N.M., Lou M., Elleman T.C., Adams T.E., Lovrecz G.O., et al. Crystal structure of a truncated epidermal growth factor receptor extracellular domain bound to transforming growth factor alpha. Cell 110 6 (2002) 763-773
    • (2002) Cell , vol.110 , Issue.6 , pp. 763-773
    • Garrett, T.P.1    McKern, N.M.2    Lou, M.3    Elleman, T.C.4    Adams, T.E.5    Lovrecz, G.O.6
  • 46
    • 0028969852 scopus 로고
    • Apoptosis induced by an anti-epidermal growth factor receptor monoclonal antibody in a human colorectal carcinoma cell line and its delay by insulin
    • Wu X., Fan Z., Masui H., Rosen N., and Mendelsohn J. Apoptosis induced by an anti-epidermal growth factor receptor monoclonal antibody in a human colorectal carcinoma cell line and its delay by insulin. J Clin Invest 95 4 (1995) 1897-1905
    • (1995) J Clin Invest , vol.95 , Issue.4 , pp. 1897-1905
    • Wu, X.1    Fan, Z.2    Masui, H.3    Rosen, N.4    Mendelsohn, J.5
  • 47
    • 0031752773 scopus 로고    scopus 로고
    • Antisense epidermal growth factor receptor RNA transfection in human malignant glioma cells leads to inhibition of proliferation and induction of differentiation
    • Tian X.X., Lam P.Y., Chen J., Pang J.C., To S.S., Di-Tomaso E., et al. Antisense epidermal growth factor receptor RNA transfection in human malignant glioma cells leads to inhibition of proliferation and induction of differentiation. Neuropathol Appl Neurobiol 24 5 (1998) 389-396
    • (1998) Neuropathol Appl Neurobiol , vol.24 , Issue.5 , pp. 389-396
    • Tian, X.X.1    Lam, P.Y.2    Chen, J.3    Pang, J.C.4    To, S.S.5    Di-Tomaso, E.6
  • 48
    • 0031045848 scopus 로고    scopus 로고
    • EGF-R dependent regulation of keratinocyte survival
    • Rodeck U., Jost M., Kari C., Shih D.T., Lavker R.M., Ewert D.L., et al. EGF-R dependent regulation of keratinocyte survival. J Cell Sci 110 Part 2 (1997) 113-121
    • (1997) J Cell Sci , vol.110 , Issue.PART 2 , pp. 113-121
    • Rodeck, U.1    Jost, M.2    Kari, C.3    Shih, D.T.4    Lavker, R.M.5    Ewert, D.L.6
  • 49
    • 0033812475 scopus 로고    scopus 로고
    • Building better vaccines: how apoptotic cell death can induce inflammation and activate innate and adaptative immunity
    • Restifo N. Building better vaccines: how apoptotic cell death can induce inflammation and activate innate and adaptative immunity. Curr Opin Immunol 12 (2000) 597-603
    • (2000) Curr Opin Immunol , vol.12 , pp. 597-603
    • Restifo, N.1
  • 50
    • 0036892577 scopus 로고    scopus 로고
    • Stressed apoptotic tumor cells stimulate dendritic cells and induce specific cytotoxic T cells
    • Fen H., Zeng Y., Graner M.W., and Katsanis E. Stressed apoptotic tumor cells stimulate dendritic cells and induce specific cytotoxic T cells. Blood 100 (2002) 4108-4115
    • (2002) Blood , vol.100 , pp. 4108-4115
    • Fen, H.1    Zeng, Y.2    Graner, M.W.3    Katsanis, E.4
  • 51
    • 0141998606 scopus 로고    scopus 로고
    • Molecular identification of a danger signal that alerts the immune system to dying cells
    • Shi Y., Evans J.E., and Rock K.L. Molecular identification of a danger signal that alerts the immune system to dying cells. Nature 425 (2003) 516-521
    • (2003) Nature , vol.425 , pp. 516-521
    • Shi, Y.1    Evans, J.E.2    Rock, K.L.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.