Activation of kappa-opioid receptors at reperfusion affords cardioprotection in both rat and mouse hearts

Basic Research in Cardiology

Volumn 103, Issue 5, 2008, Pages 454-463

  Peart, Jason N ^a   Gross, Eric R ^b   Reichelt, Melissa E ^a   Hsu, Anna ^b   Headrick, John P ^a   Gross, Garrett J ^b  

^a GRIFFITH UNIVERSITY   (Australia)

^b MEDICAL COLLEGE OF WISCONSIN   (United States)

Author keywords

Ischemia; Opioids; Postconditioning

Indexed keywords

3,4 DICHLORO N METHYL N [2 (1 PYRROLIDINYL)CYCLOHEXYL]BENZENEACETAMIDE; 5 HYDROXYDECANOIC ACID; ADENOSINE TRIPHOSPHATE SENSITIVE POTASSIUM CHANNEL; DELTA OPIATE RECEPTOR; KAPPA OPIATE RECEPTOR; KAPPA OPIATE RECEPTOR AGONIST; KAPPA OPIATE RECEPTOR ANTAGONIST; PHOSPHATIDYLINOSITOL 3 KINASE; WORTMANNIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CHANNEL GATING; CONTROLLED STUDY; ENZYME ACTIVATION; EXPERIMENTAL MODEL; HEART INFARCTION; HEART INFARCTION SIZE; HEART MUSCLE ISCHEMIA; HEART MUSCLE REPERFUSION; HEART PROTECTION; IN VITRO STUDY; IN VIVO STUDY; ISOLATED HEART; LEFT CORONARY ARTERY; MALE; MOUSE; NONHUMAN; RAT; RECEPTOR UPREGULATION; TIME; TREATMENT OUTCOME;

3,4-DICHLORO-N-METHYL-N-(2-(1-PYRROLIDINYL)-CYCLOHEXYL)-BENZENEACETAMIDE, (TRANS)-ISOMER; ANALGESICS, NON-NARCOTIC; ANIMALS; CARDIOTONIC AGENTS; ISCHEMIC PRECONDITIONING, MYOCARDIAL; MALE; MICE; MICE, INBRED C57BL; MYOCARDIAL REPERFUSION INJURY; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, OPIOID, KAPPA; SIGNAL TRANSDUCTION;

EID: 50249127712     PISSN: 03008428     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00395-008-0726-z     Document Type: Article

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