Cingulate gyrus neuroanatomy in schizophrenia subjects and their non-psychotic siblings

Schizophrenia Research

Volumn 104, Issue 1-3, 2008, Pages 61-70

  Calabrese, Daniel R ^a   Wang, Lei ^d   Harms, Michael P ^a   Ratnanather, J Tilak ^c   Barch, Deanna M ^a,b   Cloninger, C Robert ^a   Thompson, Paul A ^a   Miller, Michael I ^c   Csernansky, John G ^c  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b WASHINGTON UNIVERSITY   (United States)

^c Johns Hopkins University   (United States)

^d NORTHWESTERN UNIVERSITY   (United States)

Author keywords

Cingulated; Cortex; Depth mapping; Schizophrenia; Sibling; Thickness; Volume

Indexed keywords

ADULT; ARTICLE; BRAIN CORTEX; BRAIN MAPPING; BRAIN SIZE; CINGULATE GYRUS; CONTROLLED STUDY; COVARIANCE; FEMALE; GRAY MATTER; HUMAN; MAJOR CLINICAL STUDY; MALE; NEGATIVE SYNDROME; NEUROANATOMY; NUCLEAR MAGNETIC RESONANCE IMAGING; PRIORITY JOURNAL; SCHIZOPHRENIA; SIBLING;

COGNITION DISORDERS; DIAGNOSTIC AND STATISTICAL MANUAL OF MENTAL DISORDERS; FEMALE; FUNCTIONAL LATERALITY; GYRUS CINGULI; HUMANS; MAGNETIC RESONANCE IMAGING; MALE; NEUROPSYCHOLOGICAL TESTS; SCHIZOPHRENIA; SEVERITY OF ILLNESS INDEX; SIBLINGS; YOUNG ADULT;

EID: 50249095073     PISSN: 09209964     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.schres.2008.06.014     Document Type: Article

References (69)

1. American Psychiatric Association. Diagnostic and Statistical Manual of Mental Disorders: DSM-IV (1994), American Psychiatric Association, Washington, DC
2. Andreasen N.C. Scale for the Assessment of Negative Symptoms (SANS) (1983), University of Iowa
3. Andreasen N.C. The Scale for Assessment of Positive Symptoms (SAPS) (1984), The University of Iowa, Iowa City, Iowa
4. Anton E.S., Marchionni M.A., Lee K.F., and Rakic P. Role of GGF/neuregulin signaling in interactions between migrating neurons and radial glia in the developing cerebral cortex. Development 124 18 (1997) 3501-3510
5. Arnold S.E., Talbot K., and Hahn C.G. Neurodevelopment, neuroplasticity, and new genes for schizophrenia. Prog. Brain Res. 147 (2005) 319-345
6. Bellon A. New genes associated with schizophrenia in neurite formation: a review of cell culture experiments. Mol. Psychiatry 12 7 (2007) 620-629
7. Benes F.M., McSparren J., Bird E.D., SanGiovanni J.P., and Vincent S.L. Deficits in small interneurons in prefrontal and cingulate cortices of schizophrenic and schizoaffective patients. Arch. Gen. Psychiatry 48 11 (1991) 996-1001
8. Benes F.M. Evidence for neurodevelopment disturbances in anterior cingulate cortex of post-mortem schizophrenic brain. Schizophr. Res. 5 3 (1991) 187-188
9. Benes F.M., and Bird E.D. An analysis of the arrangement of neurons in the cingulate cortex of schizophrenic patients. Arch. Gen. Psychiatry 44 7 (1987) 608-616
10. Benes F.M., Vincent S.L., and Todtenkopf M. The density of pyramidal and nonpyramidal neurons in anterior cingulate cortex of schizophrenic and bipolar subjects. Biol. Psychiatry 50 6 (2001) 395-406
11. Boos H.B., Aleman A., Cahn W., Pol H.H., and Kahn R.S. Brain volumes in relatives of patients with schizophrenia: a meta-analysis. Arch. Gen. Psychiatry 64 3 (2007) 297-304
12. Bouras C., Kovari E., Hof P.R., Riederer B.M., and Giannakopoulos P. Anterior cingulate cortex pathology in schizophrenia and bipolar disorder. Acta Neuropathol. (Berl) 102 4 (2001) 373-379
13. Buckner R.L., Head D., Parker J., Fotenos A.F., Marcus D., Morris J.C., and Snyder A.Z. A unified approach for morphometric and functional data analysis in young, old, and demented adults using automated atlas-based head size normalization: reliability and validation against manual measurement of total intracranial volume. Neuroimage 23 2 (2004) 724-738
14. Cannon T.D., van Erp T.G., Huttunen M., Lonnqvist J., Salonen O., Valanne L., Poutanen V.P., Standertskjold-Nordenstam C.G., Gur R.E., and Yan M. Regional gray matter, white matter, and cerebrospinal fluid distributions in schizophrenic patients, their siblings, and controls. Arch. Gen. Psychiatry 55 12 (1998) 1084-1091
15. Cannon T.D., Zorrilla L.E., Shtasel D., Gur R.E., Gur R.C., Marco E.J., Moberg P., and Price R.A. Neuropsychological functioning in siblings discordant for schizophrenia and healthy volunteers. Arch. Gen. Psychiatry 51 8 (1994) 651-661
16. Cantor-Graae E. The contribution of social factors to the development of schizophrenia: a review of recent findings. Can. J. Psychiatry 52 5 (2007) 277-286
17. Cardno A.G., Marshall E.J., Coid B., Macdonald A.M., Ribchester T.R., Davies N.J., Venturi P., Jones L.A., Lewis S.W., Sham P.C., Gottesman II, Farmer A.E., McGuffin P., Reveley A.M., and Murray R.M. Heritability estimates for psychotic disorders: the Maudsley twin psychosis series. Arch. Gen. Psychiatry 56 2 (1999) 162-168
18. Chana G., Landau S., Beasley C., Everall I.P., and Cotter D. Two-dimensional assessment of cytoarchitecture in the anterior cingulate cortex in major depressive disorder, bipolar disorder, and schizophrenia: evidence for decreased neuronal somal size and increased neuronal density. Biol Psychiatry 53 12 (2003) 1086-1098
19. Chapman J.P., Chapman L.J., and Kwapil T.R. Scales for the measurement of schizotypy. In: Raine T., Lencz T., and Mednick S. (Eds). Schizotypal Personality (1995), Cambridge University Press, New York 79-106
20. Cotter D., Mackay D., Landau S., Kerwin R., and Everall I. Reduced glial cell density and neuronal size in the anterior cingulate cortex in major depressive disorder. Arch. Gen. Psychiatry 58 6 (2001) 545-553
21. Dale A.M., Fischl B., and Sereno M.I. Cortical surface-based analysis. I. Segmentation and surface reconstruction. Neuroimage 9 2 (1999) 179-194
22. Delawalla Z., Barch D.M., Fisher Eastep J.L., Thomason E.S., Hanewinkel M.J., Thompson P.A., and Csernansky J.G. Factors mediating cognitive deficits and psychopathology among siblings of individuals with schizophrenia. Schizophr. Bull. 32 3 (2006) 525-537
23. Desikan R.S., Segonne F., Fischl B., Quinn B.T., Dickerson B.C., Blacker D., Buckner R.L., Dale A.M., Maguire R.P., Hyman B.T., Albert M.S., and Killiany R.J. An automated labeling system for subdividing the human cerebral cortex on MRI scans into gyral based regions of interest. Neuroimage 31 3 (2006) 968-980
24. Dolan R.J., Fletcher P., Frith C.D., Friston K.J., Frackowiak R.S., and Grasby P.M. Dopaminergic modulation of impaired cognitive activation in the anterior cingulate cortex in schizophrenia. Nature 378 6553 (1995) 180-182
25. Farrow T.F., Whitford T.J., Williams L.M., Gomes L., and Harris A.W. Diagnosis-related regional gray matter loss over two years in first episode schizophrenia and bipolar disorder. Biol Psychiatry 58 9 (2005) 713-723
26. First, M., Spitzer, R., Gibbon, M., and Williams, J., Structured Clinical Interview for DSM-IV Axis I Disorders - Patient Edition (SCID-I/P, Version 2.0). New York, NY: Biometrics Research Department, New York State Psychiatric Institute, 1995.
27. Fischl B., Salat D.H., van der Kouwe A.J., Makris N., Segonne F., Quinn B.T., and Dale A.M. Sequence-independent segmentation of magnetic resonance images. Neuroimage 23 Suppl 1 (2004) S69-S84
28. Fischl B., Sereno M.I., and Dale A.M. Cortical surface-based analysis. II: inflation, flattening, and a surface-based coordinate system. Neuroimage 9 2 (1999) 195-207
29. Fornito A., Wood S.J., Whittle S., Fuller J., Adamson C., Saling M.M., Velakoulis D., Pantelis C., and Yucel M. Variability of the paracingulate sulcus and morphometry of the medial frontal cortex: associations with cortical thickness, surface area, volume, and sulcal depth. Hum. Brain Mapp. 29 2 (2008) 222-236
30. Fornito A., Yucel M., Wood S.J., Adamson C., Velakoulis D., Saling M.M., McGorry P.D., and Pantelis C. Surface-based morphometry of the anterior cingulate cortex in first episode schizophrenia. Hum. Brain Mapp. 29 4 (2008) 478-489
31. Garavan H., Ross T.J., Kaufman J., and Stein E.A. A midline dissociation between error-processing and response-conflict monitoring. Neuroimage 20 2 (2003) 1132-1139
32. Gogtay N., Sporn A., Clasen L.S., Greenstein D., Giedd J.N., Lenane M., Gochman P.A., Zijdenbos A., and Rapoport J.L. Structural brain MRI abnormalities in healthy siblings of patients with childhood-onset schizophrenia. Am. J. Psychiatry 160 3 (2003) 569-571
33. Ha T.H., Youn T., Ha K.S., Rho K.S., Lee J.M., Kim I.Y., Kim S.I., and Kwon J.S. Gray matter abnormalities in paranoid schizophrenia and their clinical correlations. Psychiatry Res. 132 3 (2004) 251-260
34. Han X., Xu C., and Prince J.L. A topology preserving deformable model using level set. CVPR'2001 (2001), IEEE, Kauai, HI 765-770
35. Han X., Xu C.Y., Braga-Neto U., and Prince J.L. Topology correction in brain cortex segmentation using a multiscale, graph-based algorithm. IEEE Trans. Med. Imaging 21 (2002) 109-121
36. Harms M.P., Wang L., Mamah D., Barch D.M., Thompson P.A., and Csernansky J.G. Thalamic shape abnormalities in individuals with schizophrenia and their nonpsychotic siblings. J Neurosci 27 50 (2007) 13835-13842
37. Harrison G., Gunnell D., Glazebrook C., Page K., and Kwiecinski R. Association between schizophrenia and social inequality at birth: case-control study. Br. J. Psychiatry 179 (2001) 346-350
38. Hulshoff Pol H.E., Schnack H.G., Mandl R.C., van Haren N.E., Koning H., Collins D.L., Evans A.C., and Kahn R.S. Focal gray matter density changes in schizophrenia. Arch. Gen. Psychiatry 58 12 (2001) 1118-1125
39. Job D.E., Whalley H.C., McConnell S., Glabus M., Johnstone E.C., and Lawrie S.M. Structural gray matter differences between first-episode schizophrenics and normal controls using voxel-based morphometry. Neuroimage 17 2 (2002) 880-889
40. Karlsgodt K.H., Glahn D.C., van Erp T.G., Therman S., Huttunen M., Manninen M., Kaprio J., Cohen M.S., Lonnqvist J., and Cannon T.D. The relationship between performance and fMRI signal during working memory in patients with schizophrenia, unaffected co-twins, and control subjects. Schizophr. Res. 89 1-3 (2007) 191-197
41. Kerns J.G., Cohen J.D., MacDonald III A.W., Johnson M.K., Stenger V.A., Aizenstein H., and Carter C.S. Decreased conflict- and error-related activity in the anterior cingulate cortex in subjects with schizophrenia. Am. J. Psychiatry 162 10 (2005) 1833-1839
42. Khaneja N., Grenander U., and Miller M.I. Dynamic programming generation of curves on brain surfaces. IEEE Trans. Pattern Anal. Mach. Intell. 20 10 (1998) 1260-1264
43. Kopelman A., Andreasen N.C., and Nopoulos P. Morphology of the anterior cingulate gyrus in patients with schizophrenia: relationship to typical neuroleptic exposure. Am. J. Psychiatry 162 10 (2005) 1872-1878
44. Lenroot R.K., Schmitt J.E., Ordaz S.J., Wallace G.L., Neale M.C., Lerch J.P., Kendler K.S., Evans A.C., and Giedd J.N. Differences in genetic and environmental influences on the human cerebral cortex associated with development during childhood and adolescence. Hum. Brain Mapp. (2007)
45. Lieberman J.A., Tollefson G.D., Charles C., Zipursky R., Sharma T., Kahn R.S., Keefe R.S., Green A.I., Gur R.E., McEvoy J., Perkins D., Hamer R.M., Gu H., and Tohen M. Antipsychotic drug effects on brain morphology in first-episode psychosis. Arch. Gen. Psychiatry 62 4 (2005) 361-370
46. Mamah, D., Harms, M.P., Wang, L., Barch, D., Thompson, P., Kim, J., Miller, M.I., Csernansky, J.G., 2008. Basal ganglia shape abnormalities in the unaffected siblings of schizophrenia patients. Biol. Psychiatry 64, 111-120.
47. Mayes A.R., Montaldi D., Spencer T.J., and Roberts N. Recalling spatial information as a component of recently and remotely acquired episodic or semantic memories: an fMRI study. Neuropsychology 18 3 (2004) 426-441
48. McCormick L., Decker L., Nopoulos P., Ho B.C., and Andreasen N. Effects of atypical and typical neuroleptics on anterior cingulate volume in schizophrenia. Schizophr. Res. 80 1 (2005) 73-84
49. Miller M.I., Hosakere M., Barker A.R., Priebe C.E., Lee N., Ratnanather J.T., Wang L., Gado M., Morris J.C., and Csernansky J.G. Labeled cortical mantle distance maps of the cingulate quantify differences between dementia of the Alzheimer type and healthy aging. Proc. Natl. Acad. Sci. U S A 100 25 (2003) 15172-15177
50. Miller M.I., Massie A.B., Ratnanather J.T., Botteron K.N., and Csernansky J.G. Bayesian construction of geometrically based cortical thickness metrics. Neuroimage 12 6 (2000) 676-687
51. Miller T.J., McGlashan T.H., Woods S.W., Stein K., Driesen N., Corcoran C.M., Hoffman R., and Davidson L. Symptom assessment in schizophrenic prodromal states. Psychiatr. Q. 70 4 (1999) 273-287
52. Mitelman S.A., Shihabuddin L., Brickman A.M., Hazlett E.A., and Buchsbaum M.S. MRI assessment of gray and white matter distribution in Brodmann's areas of the cortex in patients with schizophrenia with good and poor outcomes. Am. J. Psychiatry 160 12 (2003) 2154-2168
53. Miyoshi K., Honda A., Baba K., Taniguchi M., Oono K., Fujita T., Kuroda S., Katayama T., and Tohyama M. Disrupted-In-Schizophrenia 1, a candidate gene for schizophrenia, participates in neurite outgrowth. Mol. Psychiatry 8 7 (2003) 685-694
54. Narr K.L., Toga A.W., Szeszko P., Thompson P.M., Woods R.P., Robinson D., Sevy S., Wang Y., Schrock K., and Bilder R.M. Cortical thinning in cingulate and occipital cortices in first episode schizophrenia. Biol. Psychiatry 58 1 (2005) 32-40
55. Olney J.W., and Farber N.B. NMDA antagonists as neurotherapeutic drugs, psychotogens, neurotoxins, and research tools for studying schizophrenia. Neuropsychopharmacology 13 4 (1995) 335-345
56. Ongur D., Ferry A.T., and Price J.L. Architectonic subdivision of the human orbital and medial prefrontal cortex. J. Comp. Neurol. 460 3 (2003) 425-449
57. Priebe C.E., Miller M.I., and Tilak Ratnanather J. Segmenting magnetic resonance images via hierarchical mixture modelling. Comput. Stat. Data Anal. 50 2 (2006) 551-567
58. Ratnanather J.T., Wang L., Nebel M.B., Hosakere M., Han X., Csernansky J.G., and Miller M.I. Validation of semiautomated methods for quantifying cingulate cortical metrics in schizophrenia. Psychiatry Res. 132 1 (2004) 53-68
59. Rio C., Rieff H.I., Qi P., Khurana T.S., and Corfas G. Neuregulin and erbB receptors play a critical role in neuronal migration. Neuron 19 1 (1997) 39-50
60. Segonne F., Pacheco J., and Fischl B. Geometrically accurate topology-correction of cortical surfaces using nonseparating loops. IEEE Trans. Med. Imaging 26 4 (2007) 518-529
61. Shapleske J., Rossell S.L., Chitnis X.A., Suckling J., Simmons A., Bullmore E.T., Woodruff P.W., and David A.S. A computational morphometric MRI study of schizophrenia: effects of hallucinations. Cereb. Cortex 12 12 (2002) 1331-1341
62. Sigmundsson T., Suckling J., Maier M., Williams S., Bullmore E., Greenwood K., Fukuda R., Ron M., and Toone B. Structural abnormalities in frontal, temporal, and limbic regions and interconnecting white matter tracts in schizophrenic patients with prominent negative symptoms. Am. J. Psychiatry 158 2 (2001) 234-243
63. Sowell E.R., Levitt J., Thompson P.M., Holmes C.J., Blanton R.E., Kornsand D.S., Caplan R., McCracken J., Asarnow R., and Toga A.W. Brain abnormalities in early-onset schizophrenia spectrum disorder observed with statistical parametric mapping of structural magnetic resonance images. Am. J. Psychiatry 157 9 (2000) 1475-1484
64. Staal W.G., Hulshoff Pol H.E., Schnack H., van der Schot A.C., and Kahn R.S. Partial volume decrease of the thalamus in relatives of patients with schizophrenia. Am. J. Psychiatry 155 12 (1998) 1784-1786
65. Todtenkopf M.S., Vincent S.L., and Benes F.M. A cross-study meta-analysis and three-dimensional comparison of cell counting in the anterior cingulate cortex of schizophrenic and bipolar brain. Schizophr. Res. 73 1 (2005) 79-89
66. Vidal C.N., Rapoport J.L., Hayashi K.M., Geaga J.A., Sui Y., McLemore L.E., Alaghband Y., Giedd J.N., Gochman P., Blumenthal J., Gogtay N., Nicolson R., Toga A.W., and Thompson P.M. Dynamically spreading frontal and cingulate deficits mapped in adolescents with schizophrenia. Arch. Gen. Psychiatry 63 1 (2006) 25-34
67. Wang L., Hosakere M., Trein J.C., Miller A., Ratnanather J.T., Barch D.M., Thompson P.A., Qiu A., Gado M.H., Miller M.I., and Csernansky J.G. Abnormalities of cingulate gyrus neuroanatomy in schizophrenia. Schizophr. Res. 93 1-3 (2007) 66-78
68. Wicks S., Hjern A., Gunnell D., Lewis G., and Dalman C. Social adversity in childhood and the risk of developing psychosis: a national cohort study. Am. J. Psychiatry 162 9 (2005) 1652-1657
69. Yucel M., Stuart G.W., Maruff P., Velakoulis D., Crowe S.F., Savage G., and Pantelis C. Hemispheric and gender-related differences in the gross morphology of the anterior cingulate/paracingulate cortex in normal volunteers: an MRI morphometric study. Cereb. Cortex 11 1 (2001) 17-25