-
1
-
-
0031008223
-
Herpes simplex virus DNA replication
-
Boehmer, P. E., and Lehman, I. R. (1997) Herpes simplex virus DNA replication. Annu. Rev. Biochem. 66, 347-384.
-
(1997)
Annu. Rev. Biochem
, vol.66
, pp. 347-384
-
-
Boehmer, P.E.1
Lehman, I.R.2
-
2
-
-
0037377759
-
Recruitment of polymerase to herpes simplex virus type 1 replication foci in cells expressing mutant primase (UL52) proteins
-
Carrington-Lawrence, S. D., and Weller, S. K. (2003) Recruitment of polymerase to herpes simplex virus type 1 replication foci in cells expressing mutant primase (UL52) proteins. J. Virol. 77, 4237-4247.
-
(2003)
J. Virol
, vol.77
, pp. 4237-4247
-
-
Carrington-Lawrence, S.D.1
Weller, S.K.2
-
3
-
-
0036107516
-
Herpes simplex virus helicase-primase inhibitors are active in animal models of human disease
-
Crute, J. J., Ctygon, C. A., Hargrave, K. D., Simoneau, B., Faucher, A. M., Bolger, G., Kibler, P., Liuzzi, M., and Cordingley, M. G. (2002) Herpes simplex virus helicase-primase inhibitors are active in animal models of human disease. Nature Medicine 8, 386-391.
-
(2002)
Nature Medicine
, vol.8
, pp. 386-391
-
-
Crute, J.J.1
Ctygon, C.A.2
Hargrave, K.D.3
Simoneau, B.4
Faucher, A.M.5
Bolger, G.6
Kibler, P.7
Liuzzi, M.8
Cordingley, M.G.9
-
4
-
-
0025292145
-
Herpes simplex virus helicase-primase: The UL8 protein is not required for DNA-dependent ATPase and DNA helicase activities
-
Calder, J. M., and Stow, N. D. (1990) Herpes simplex virus helicase-primase: the UL8 protein is not required for DNA-dependent ATPase and DNA helicase activities. Nucleic Acids Res. 18, 3573-3578.
-
(1990)
Nucleic Acids Res
, vol.18
, pp. 3573-3578
-
-
Calder, J.M.1
Stow, N.D.2
-
5
-
-
0026073154
-
Association of DNA helicase and primase activities with a subassembly of the herpes simplex virus 1 helicase-primase composed of the UL5 and UL52 gene products
-
Dodson, M. S., and Lehman, I. R. (1991) Association of DNA helicase and primase activities with a subassembly of the herpes simplex virus 1 helicase-primase composed of the UL5 and UL52 gene products. Proc. Natl. Acad. Sci. U.S.A. 88, 1105-1109.
-
(1991)
Proc. Natl. Acad. Sci. U.S.A
, vol.88
, pp. 1105-1109
-
-
Dodson, M.S.1
Lehman, I.R.2
-
6
-
-
0026632424
-
The UL8 subunit of the herpes simplex virus helicase-primase complex is required for efficient primer utilization
-
Sherman, G., Gottlieb, J., and Challberg, M. D. (1992) The UL8 subunit of the herpes simplex virus helicase-primase complex is required for efficient primer utilization. J. Virol. 66, 4884-48892.
-
(1992)
J. Virol
, vol.66
, pp. 4884-48892
-
-
Sherman, G.1
Gottlieb, J.2
Challberg, M.D.3
-
7
-
-
0030930191
-
The UL8 subunit of the heterotrimeric herpes simplex virus type 1 helicase-primase is required for the unwinding of single stand DNA-binding protein (ICP8)-coated DNA substrates
-
Falkenberg, M., Bushnell, D. A., Elias, P., and Lehman, I. R. (1997) The UL8 subunit of the heterotrimeric herpes simplex virus type 1 helicase-primase is required for the unwinding of single stand DNA-binding protein (ICP8)-coated DNA substrates. J. Biol. Chem. 272, 22766-22770.
-
(1997)
J. Biol. Chem
, vol.272
, pp. 22766-22770
-
-
Falkenberg, M.1
Bushnell, D.A.2
Elias, P.3
Lehman, I.R.4
-
8
-
-
0007398685
-
Herpes simplex virus type-1 single-strand DNA-binding protein (ICP8) enhances the ability of the viral DNA helicase-primase to unwind cisplatin-modified DNA
-
Gac, N. T. L., Villani, G., and Boehmer, P. E. (1998) Herpes simplex virus type-1 single-strand DNA-binding protein (ICP8) enhances the ability of the viral DNA helicase-primase to unwind cisplatin-modified DNA. J. Biol. Chem. 273, 13801-13807.
-
(1998)
J. Biol. Chem
, vol.273
, pp. 13801-13807
-
-
Gac, N.T.L.1
Villani, G.2
Boehmer, P.E.3
-
9
-
-
0030795032
-
The catalytic subunit of the DNA polymerase of herpes simplex virus type 1 interacts specifically with the C terminus of the UL8 component of the viral helicase-primase complex
-
Mardsen, H. S., McLean, G. W., Barnard, E. C., Francis, G. J., MacEachran, K., Murphy, M., McVey, G., Cross, A., Abbotts, A. P., and Stow, N. D. (1997) The catalytic subunit of the DNA polymerase of herpes simplex virus type 1 interacts specifically with the C terminus of the UL8 component of the viral helicase-primase complex. J. Virol. 71, 6390-6397.
-
(1997)
J. Virol
, vol.71
, pp. 6390-6397
-
-
Mardsen, H.S.1
McLean, G.W.2
Barnard, E.C.3
Francis, G.J.4
MacEachran, K.5
Murphy, M.6
McVey, G.7
Cross, A.8
Abbotts, A.P.9
Stow, N.D.10
-
10
-
-
0027991973
-
The herpes simplex virus type 1 origin-binding protein interacts specifically with the viral UL8 protein
-
McLean, G. W., Abbotts, A. P., Parry, M. E., Marsden, H. S., and Stow, N. D. (1994) The herpes simplex virus type 1 origin-binding protein interacts specifically with the viral UL8 protein. J. Gen. Virol. 75, 2699-2706.
-
(1994)
J. Gen. Virol
, vol.75
, pp. 2699-2706
-
-
McLean, G.W.1
Abbotts, A.P.2
Parry, M.E.3
Marsden, H.S.4
Stow, N.D.5
-
11
-
-
0028075341
-
The UL8 component of the herpes simplex virus helicase-primase complex stimulates primer synthesis by a subassembly of the UL5 and UL52 components
-
Tenney, D. J., Hurlburt, W. W., Micheletti, P. A., Bifano, M., and Hamatake, R. K. (1994) The UL8 component of the herpes simplex virus helicase-primase complex stimulates primer synthesis by a subassembly of the UL5 and UL52 components. J. Biol. Chem. 269, 5030-5035.
-
(1994)
J. Biol. Chem
, vol.269
, pp. 5030-5035
-
-
Tenney, D.J.1
Hurlburt, W.W.2
Micheletti, P.A.3
Bifano, M.4
Hamatake, R.K.5
-
12
-
-
0037058824
-
-
Ramirez-Aguilar, K. A., Low-Nam, N. A., and Kuchta, R. D. (2002) Key role of template sequence for primer synthesis by the herpes simplex virus 1 helicase-primase. Biochemistry 41, 4569-4579.
-
Ramirez-Aguilar, K. A., Low-Nam, N. A., and Kuchta, R. D. (2002) Key role of template sequence for primer synthesis by the herpes simplex virus 1 helicase-primase. Biochemistry 41, 4569-4579.
-
-
-
-
13
-
-
0022852279
-
Studies of the DNA helicase-RNA primase unit from bacteriophage T4. A trinucleotide sequence on the DNA template starts RNA primer synthesis
-
Cha, T. A., and Alberts, B. M. (1986) Studies of the DNA helicase-RNA primase unit from bacteriophage T4. A trinucleotide sequence on the DNA template starts RNA primer synthesis. J. Biol. Chem. 261, 7001-7010.
-
(1986)
J. Biol. Chem
, vol.261
, pp. 7001-7010
-
-
Cha, T.A.1
Alberts, B.M.2
-
14
-
-
0024806757
-
Structural features of the priming signal recognized by primase: Mutational analysis of the phage G4 origin of complementary DNA strand synthesis
-
Hiasa, H., Sakai, H., Tanaka, K., Honda, Y., Komano, T., and Godson, G. N. (1989) Structural features of the priming signal recognized by primase: mutational analysis of the phage G4 origin of complementary DNA strand synthesis. Gene 84, 9-16.
-
(1989)
Gene
, vol.84
, pp. 9-16
-
-
Hiasa, H.1
Sakai, H.2
Tanaka, K.3
Honda, Y.4
Komano, T.5
Godson, G.N.6
-
15
-
-
0026356394
-
Requirements for primer synthesis by bacteriophage T7 63-kDa gene 4 protein. Roles of template sequence and T7 56-kDa gene 4 protein
-
Mendelman, L. V., and Richardson, C. C. (1991) Requirements for primer synthesis by bacteriophage T7 63-kDa gene 4 protein. Roles of template sequence and T7 56-kDa gene 4 protein. J. Biol. Chem. 266, 23240-23250.
-
(1991)
J. Biol. Chem
, vol.266
, pp. 23240-23250
-
-
Mendelman, L.V.1
Richardson, C.C.2
-
16
-
-
0025782760
-
Specificity of recognition sequence for Eschericia coli primase
-
Yoda, K., and Okazaki, T. (1991) Specificity of recognition sequence for Eschericia coli primase. Mol. Gen. Genet. 227, 1-8.
-
(1991)
Mol. Gen. Genet
, vol.227
, pp. 1-8
-
-
Yoda, K.1
Okazaki, T.2
-
17
-
-
0027513148
-
The mechanism of calf thymus DNA primase: Slow initiation, rapid polymerization and intelligent termination
-
Sheaff, R., and Kuchta, R. D. (1993) The mechanism of calf thymus DNA primase: slow initiation, rapid polymerization and intelligent termination. Biochemistry 32, 3027-3037.
-
(1993)
Biochemistry
, vol.32
, pp. 3027-3037
-
-
Sheaff, R.1
Kuchta, R.D.2
-
19
-
-
3142762309
-
Herpes simplex virus I DNA primase: A polymerase with extraordinarily low fidelity
-
Ramirez-Aguilar, K. A., and Kuchta, R. D. (2004) Herpes simplex virus I DNA primase: a polymerase with extraordinarily low fidelity. Biochemistry 43, 9084-9091.
-
(2004)
Biochemistry
, vol.43
, pp. 9084-9091
-
-
Ramirez-Aguilar, K.A.1
Kuchta, R.D.2
-
20
-
-
28244441232
-
Herpes simplex virus I primase employs watson-crick hydrogen bonding to identify cognate NTPs
-
Ramirez-Aguilar, K. A., Moore, C. L., and Kuchta, R. D. (2005) Herpes simplex virus I primase employs watson-crick hydrogen bonding to identify cognate NTPs. Biochemistry 44, 15585-15593.
-
(2005)
Biochemistry
, vol.44
, pp. 15585-15593
-
-
Ramirez-Aguilar, K.A.1
Moore, C.L.2
Kuchta, R.D.3
-
21
-
-
33846300306
-
Human DNA polymerase alpha uses a combination of positive and negative selectivity to polymerize purine dNTPs with high fidelity
-
Beckman, J., Kincaid, K., Hocek, M., Spratt, T., Engels, J., Cosstick, R., and Kuchta, R. D. (2007) Human DNA polymerase alpha uses a combination of positive and negative selectivity to polymerize purine dNTPs with high fidelity. Biochemistry 46, 448-460.
-
(2007)
Biochemistry
, vol.46
, pp. 448-460
-
-
Beckman, J.1
Kincaid, K.2
Hocek, M.3
Spratt, T.4
Engels, J.5
Cosstick, R.6
Kuchta, R.D.7
-
22
-
-
0028928572
-
Acyclic guanosine analogs inhibit DNA polymerases alpha, delta and epsilon with very different potencies and have unique mechanisms of action
-
Ilsley, D. I., Lee, S. H., Miller, W., and Kuchta, R. D. (1995) Acyclic guanosine analogs inhibit DNA polymerases alpha, delta and epsilon with very different potencies and have unique mechanisms of action. Biochemistry 34, 2504-2510.
-
(1995)
Biochemistry
, vol.34
, pp. 2504-2510
-
-
Ilsley, D.I.1
Lee, S.H.2
Miller, W.3
Kuchta, R.D.4
-
23
-
-
0025970299
-
Inhibition of DNA primase by 9-beta-D-arabinofuranosyladenosine triphosphate
-
Kuchta, R. D., and Willhelm, L. (1991) Inhibition of DNA primase by 9-beta-D-arabinofuranosyladenosine triphosphate. Biochemistry 30, 797-803.
-
(1991)
Biochemistry
, vol.30
, pp. 797-803
-
-
Kuchta, R.D.1
Willhelm, L.2
-
24
-
-
0026637347
-
Inhibition of DNA primase and polymerase alpha by arabinofuranosylnucleoside triphosphates and related compounds
-
Kuchta, R. D., Ilsley, D., Kravig, K. D., Schubert, S., and Harris, B. (1992) Inhibition of DNA primase and polymerase alpha by arabinofuranosylnucleoside triphosphates and related compounds. Biochemistry 31, 4720-4728.
-
(1992)
Biochemistry
, vol.31
, pp. 4720-4728
-
-
Kuchta, R.D.1
Ilsley, D.2
Kravig, K.D.3
Schubert, S.4
Harris, B.5
-
25
-
-
0042318450
-
Facile polymerization of dNTPs bearing unatural base analogues by DNA polymerase alpha and klenow fragment (DNA polymerase I)
-
Chiaramonte, M., Moore, C. L., Kincaid, K., and Kuchta, R. D. (2003) Facile polymerization of dNTPs bearing unatural base analogues by DNA polymerase alpha and klenow fragment (DNA polymerase I). Biochemistry 42, 10472-10481.
-
(2003)
Biochemistry
, vol.42
, pp. 10472-10481
-
-
Chiaramonte, M.1
Moore, C.L.2
Kincaid, K.3
Kuchta, R.D.4
-
26
-
-
1042265191
-
Mechanism of primer synthesis by the herpes simplex virus 1 helicase-primase
-
Ramirez-Aguilar, K., and Kuchta, R. D. (2004) Mechanism of primer synthesis by the herpes simplex virus 1 helicase-primase. Biochemistry 43, 1103-1112.
-
(2004)
Biochemistry
, vol.43
, pp. 1103-1112
-
-
Ramirez-Aguilar, K.1
Kuchta, R.D.2
-
27
-
-
0026464542
-
Kinetic characterization of the polymerase and exonuclease activities of the gene 43 protein of bacteriophage T4
-
Capson, T., Peliska, J. A., Kaboord, B. F., West, M. F., Lively, C., Dahlberg, M., and Benkovic, S. J. (1992) Kinetic characterization of the polymerase and exonuclease activities of the gene 43 protein of bacteriophage T4. Biochemistry 31, 10984-10994.
-
(1992)
Biochemistry
, vol.31
, pp. 10984-10994
-
-
Capson, T.1
Peliska, J.A.2
Kaboord, B.F.3
West, M.F.4
Lively, C.5
Dahlberg, M.6
Benkovic, S.J.7
-
28
-
-
14644432415
-
Base selectivity is impaired by mutants that perturb hydrogen bonding networks in the RB69 DNA polymerase active site
-
Yang, G., Wang, J., and Konigsberg, W. (2005) Base selectivity is impaired by mutants that perturb hydrogen bonding networks in the RB69 DNA polymerase active site. Biochemistry 44, 3338-3346.
-
(2005)
Biochemistry
, vol.44
, pp. 3338-3346
-
-
Yang, G.1
Wang, J.2
Konigsberg, W.3
-
29
-
-
33747462891
-
A new paradigm for DNA polymerase specificity
-
Tsai, Y.-C., and Johnson, K. A. (2006) A new paradigm for DNA polymerase specificity. Biochemistry 45, 9675-9687.
-
(2006)
Biochemistry
, vol.45
, pp. 9675-9687
-
-
Tsai, Y.-C.1
Johnson, K.A.2
-
30
-
-
0025051277
-
DNA primase: Processivity and the primase to polymerase alpha activity switch
-
Kuchta, R. D., Reid, B., and Chang, L. M. S. (1990) DNA primase: processivity and the primase to polymerase alpha activity switch. J. Biol. Chem. 265, 16158-16165.
-
(1990)
J. Biol. Chem
, vol.265
, pp. 16158-16165
-
-
Kuchta, R.D.1
Reid, B.2
Chang, L.M.S.3
-
31
-
-
0037180395
-
Synthesis of nucleotide analogues that potently and selectively inhibit human primase
-
Moore, C. L., Chiaramonte, M., Higgins, T., and Kuchta, R. D. (2002) Synthesis of nucleotide analogues that potently and selectively inhibit human primase. Biochemistry 41, 14066-14075.
-
(2002)
Biochemistry
, vol.41
, pp. 14066-14075
-
-
Moore, C.L.1
Chiaramonte, M.2
Higgins, T.3
Kuchta, R.D.4
-
32
-
-
8844232440
-
Polymerization of the triphosphates of AraC 2′,2′-difluorodeoxycytidine and ThioAraC by human DNA polymerase alpha and DNA primase
-
Richardson, K. A., Vega, T. P., Moore, C. L., Rohloff, J. C., Tomkinson, B., Bendele, R. A., Richardson, F. C., and Kuchta, R. D. (2004) Polymerization of the triphosphates of AraC 2′,2′-difluorodeoxycytidine and ThioAraC by human DNA polymerase alpha and DNA primase. Biochem. Pharmacol. 68, 2337-2346.
-
(2004)
Biochem. Pharmacol
, vol.68
, pp. 2337-2346
-
-
Richardson, K.A.1
Vega, T.P.2
Moore, C.L.3
Rohloff, J.C.4
Tomkinson, B.5
Bendele, R.A.6
Richardson, F.C.7
Kuchta, R.D.8
-
33
-
-
0028038222
-
Misincorporation of nucleotides by calf thymus DNA primase and elongation of primers containing multiple non-cognate nucleotides by DNA polymerase alpha
-
Sheaff, R., and Kuchta, R. D. (1994) Misincorporation of nucleotides by calf thymus DNA primase and elongation of primers containing multiple non-cognate nucleotides by DNA polymerase alpha. J. Biol. Chem. 269, 19225-19231.
-
(1994)
J. Biol. Chem
, vol.269
, pp. 19225-19231
-
-
Sheaff, R.1
Kuchta, R.D.2
-
34
-
-
22444435033
-
Origin and evolution of the archaeo-eukaryotic primase superfamily and related palm-domain proteins: Structural insights and new members
-
Lakshminarayan, M. I., Koonin, E. V., Leipe, D. D., and Aravind, L. (2005) Origin and evolution of the archaeo-eukaryotic primase superfamily and related palm-domain proteins: structural insights and new members. Nucleic Acids Res. 33, 3875-3896w.
-
(2005)
Nucleic Acids Res
, vol.33
-
-
Lakshminarayan, M.I.1
Koonin, E.V.2
Leipe, D.D.3
Aravind, L.4
-
35
-
-
0028998313
-
Identification of the Primase active site of the herpes simplex virus type I helicase-primase
-
Dracheva, S., Koonin, E. V., and Crute, J. J. (1995) Identification of the Primase active site of the herpes simplex virus type I helicase-primase. J. Biol. Chem. 270, 14148-14153.
-
(1995)
J. Biol. Chem
, vol.270
, pp. 14148-14153
-
-
Dracheva, S.1
Koonin, E.V.2
Crute, J.J.3
-
36
-
-
0033564245
-
Arg304 of human DNA primase is a key contributor to catalysis and NTP binding: Primase and the family X polymerases share significant sequence homology
-
Kirk, B. W., and Kuchta, R. D. (1999) Arg304 of human DNA primase is a key contributor to catalysis and NTP binding: primase and the family X polymerases share significant sequence homology. Biochemistry 38, 7727-7737.
-
(1999)
Biochemistry
, vol.38
, pp. 7727-7737
-
-
Kirk, B.W.1
Kuchta, R.D.2
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