-
1
-
-
0025829227
-
In-vitro matured human macrophages express Alzheimer's beta A4-amyloid precursor protein indicating synthesis in microglial cells
-
Bauer J., König G., Strauss S., Jonas U., Ganter U., Weidemann A., Mönning U., Masters C.L., Volk B., and Berger M. In-vitro matured human macrophages express Alzheimer's beta A4-amyloid precursor protein indicating synthesis in microglial cells. FEBS Lett. 282 (1991) 335-340
-
(1991)
FEBS Lett.
, vol.282
, pp. 335-340
-
-
Bauer, J.1
König, G.2
Strauss, S.3
Jonas, U.4
Ganter, U.5
Weidemann, A.6
Mönning, U.7
Masters, C.L.8
Volk, B.9
Berger, M.10
-
2
-
-
0030037586
-
Beta-amyloid peptide secretion by a microglial cell line is induced by beta-amyloid-(25-35) and lipopolysaccharide
-
Bitting L., Naidu A., Cordell B., and Murphy Jr. G.M. Beta-amyloid peptide secretion by a microglial cell line is induced by beta-amyloid-(25-35) and lipopolysaccharide. J. Biol. Chem. 271 (1996) 16084-16089
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 16084-16089
-
-
Bitting, L.1
Naidu, A.2
Cordell, B.3
Murphy Jr., G.M.4
-
3
-
-
38349107593
-
The Alzheimer's disease beta-secretase enzyme, BACE1
-
Cole S.L., and Vassar R. The Alzheimer's disease beta-secretase enzyme, BACE1. Mol. Neurodegener. 2 (2007) 22
-
(2007)
Mol. Neurodegener.
, vol.2
, pp. 22
-
-
Cole, S.L.1
Vassar, R.2
-
4
-
-
0037431082
-
Aph-1, Pen-2, and Nicastrin with Presenilin generate an active g-Secretase complex
-
De Strooper B. Aph-1, Pen-2, and Nicastrin with Presenilin generate an active g-Secretase complex. Neuron 38 (2003) 9-12
-
(2003)
Neuron
, vol.38
, pp. 9-12
-
-
De Strooper, B.1
-
5
-
-
0034049944
-
Proteolytic processing and cell biological functions of the amyloid precursor protein
-
De Strooper B., and Annaert W. Proteolytic processing and cell biological functions of the amyloid precursor protein. J. Cell Sci. 113 Pt 11 (2000) 1857-1870
-
(2000)
J. Cell Sci.
, vol.113
, Issue.PART 11
, pp. 1857-1870
-
-
De Strooper, B.1
Annaert, W.2
-
6
-
-
9244246339
-
Lithium decreases secretion of Ab1-42 and C-truncated species Ab1-37/38/39/40 in chicken telencephalic cultures but specifically increases intracellular Ab1-38
-
Esselmann H., Maler J.M., Kunz N., Otto M., Paul S., Lewczuk P., Rüther E., Kornhuber J., and Wiltfang J. Lithium decreases secretion of Ab1-42 and C-truncated species Ab1-37/38/39/40 in chicken telencephalic cultures but specifically increases intracellular Ab1-38. Neurodegener. Dis. 1 (2004) 236-241
-
(2004)
Neurodegener. Dis.
, vol.1
, pp. 236-241
-
-
Esselmann, H.1
Maler, J.M.2
Kunz, N.3
Otto, M.4
Paul, S.5
Lewczuk, P.6
Rüther, E.7
Kornhuber, J.8
Wiltfang, J.9
-
7
-
-
33750825049
-
High sensitivity analysis of amyloid-b peptide composition in amyloid deposits from human and PS2APP mouse brain
-
Güntert A., Döbeli H., and Bohrmann B. High sensitivity analysis of amyloid-b peptide composition in amyloid deposits from human and PS2APP mouse brain. Neuroscience 143 (2006) 461-475
-
(2006)
Neuroscience
, vol.143
, pp. 461-475
-
-
Güntert, A.1
Döbeli, H.2
Bohrmann, B.3
-
8
-
-
1442264828
-
Take five-BACE and the g-secretase quartet conduct Alzheimer's amyloid b-peptide generation
-
Haass C. Take five-BACE and the g-secretase quartet conduct Alzheimer's amyloid b-peptide generation. EMBO J. 23 (2004) 483-488
-
(2004)
EMBO J.
, vol.23
, pp. 483-488
-
-
Haass, C.1
-
9
-
-
0030769091
-
Distinct sites of intracellular production for Alzheimer's disease A beta40/42 amyloid peptides
-
Hartmann T., Bieger S.C., Bruhl B., Tienari P.J., Ida N., Allsop D., Roberts G.W., Masters C.L., Dotti C.G., Unsicker K., and Beyreuther K. Distinct sites of intracellular production for Alzheimer's disease A beta40/42 amyloid peptides. Nat. Med. 3 (1997) 1016-1020
-
(1997)
Nat. Med.
, vol.3
, pp. 1016-1020
-
-
Hartmann, T.1
Bieger, S.C.2
Bruhl, B.3
Tienari, P.J.4
Ida, N.5
Allsop, D.6
Roberts, G.W.7
Masters, C.L.8
Dotti, C.G.9
Unsicker, K.10
Beyreuther, K.11
-
10
-
-
44649183443
-
Prediction of Alzheimer's disease using a cerebro-spinal fluid pattern of C-terminally truncated beta-amyloid peptides
-
Hoglund K., Hansson O., Buchhave P., Zetterberg H., Lewczuk P., Londos E., Blennow K., Minthon L., and Wiltfang J. Prediction of Alzheimer's disease using a cerebro-spinal fluid pattern of C-terminally truncated beta-amyloid peptides. Neurodegener. Dis. (2008)
-
(2008)
Neurodegener. Dis.
-
-
Hoglund, K.1
Hansson, O.2
Buchhave, P.3
Zetterberg, H.4
Lewczuk, P.5
Londos, E.6
Blennow, K.7
Minthon, L.8
Wiltfang, J.9
-
11
-
-
0029661424
-
Analysis of heterogeneous A4 peptides in human cerebrospinal fluid and blood by a newly developed sensitive Western blot assay
-
Ida N., Hartmann T., Pantel J., Schroder J., Zerfass R., Forstl H., Sandbrink R., Masters C.L., and Beyreuther K. Analysis of heterogeneous A4 peptides in human cerebrospinal fluid and blood by a newly developed sensitive Western blot assay. J. Biol. Chem. 271 (1996) 22908-22914
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 22908-22914
-
-
Ida, N.1
Hartmann, T.2
Pantel, J.3
Schroder, J.4
Zerfass, R.5
Forstl, H.6
Sandbrink, R.7
Masters, C.L.8
Beyreuther, K.9
-
12
-
-
0033133456
-
β-Amyloid precursor protein is detectable on monocytes and is increased in Alzheimer's disease
-
Jung S.S., Gauthier S., and Cashman N.R. β-Amyloid precursor protein is detectable on monocytes and is increased in Alzheimer's disease. Neurobiol. Aging 20 (1999) 249-257
-
(1999)
Neurobiol. Aging
, vol.20
, pp. 249-257
-
-
Jung, S.S.1
Gauthier, S.2
Cashman, N.R.3
-
13
-
-
27744500854
-
γ-Secretase is a functional component of phagosomes
-
Jutras I., Laplante A., Boulais J., Brunet S., Thinakaran G., and Desjardins M. γ-Secretase is a functional component of phagosomes. J. Biol. Chem. 280 (2005) 36310-36317
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 36310-36317
-
-
Jutras, I.1
Laplante, A.2
Boulais, J.3
Brunet, S.4
Thinakaran, G.5
Desjardins, M.6
-
14
-
-
0028865607
-
Calpain inhibitor I decreases β A4 secretion from human embryonal kidney cells expressing β -amyloid precursor protein carrying the APP670/671 double mutation
-
Klafki H.W., Paganetti P.A., Sommer B., and Staufenbiel M. Calpain inhibitor I decreases β A4 secretion from human embryonal kidney cells expressing β -amyloid precursor protein carrying the APP670/671 double mutation. Neurosci. Lett. 201 (1995) 29-32
-
(1995)
Neurosci. Lett.
, vol.201
, pp. 29-32
-
-
Klafki, H.W.1
Paganetti, P.A.2
Sommer, B.3
Staufenbiel, M.4
-
15
-
-
0031559602
-
Isolation, chemical characterization, and quantitation of Aβ 3-pyroglutamyl peptide from neuritic plaques and vascular amyloid deposits
-
Kuo Y.M., Emmerling M.R., Woods A.S., Cotter R.J., and Roher A.E. Isolation, chemical characterization, and quantitation of Aβ 3-pyroglutamyl peptide from neuritic plaques and vascular amyloid deposits. Biochem. Biophys. Res. Commun. 237 (1997) 188-191
-
(1997)
Biochem. Biophys. Res. Commun.
, vol.237
, pp. 188-191
-
-
Kuo, Y.M.1
Emmerling, M.R.2
Woods, A.S.3
Cotter, R.J.4
Roher, A.E.5
-
16
-
-
9144271212
-
Electrophoretic separation of amyloid β peptides in plasma
-
Lewczuk P., Esselmann H., Bibl M., Paul S., Svitek J., Miertschischk J., Meyrer R., Smirnov A., Maler J.M., Klein C., Otto M., Bleich S., Sperling W., Kornhuber J., Rüther E., and Wiltfang J. Electrophoretic separation of amyloid β peptides in plasma. Electrophoresis 25 (2004) 3336-3343
-
(2004)
Electrophoresis
, vol.25
, pp. 3336-3343
-
-
Lewczuk, P.1
Esselmann, H.2
Bibl, M.3
Paul, S.4
Svitek, J.5
Miertschischk, J.6
Meyrer, R.7
Smirnov, A.8
Maler, J.M.9
Klein, C.10
Otto, M.11
Bleich, S.12
Sperling, W.13
Kornhuber, J.14
Rüther, E.15
Wiltfang, J.16
-
17
-
-
0032860931
-
The amyloid precursor protein of Alzheimer disease in human brain and blood
-
Li Q.X., Fuller S.J., Beyreuther K., and Masters C.L. The amyloid precursor protein of Alzheimer disease in human brain and blood. J. Leukoc. Biol. 66 (1999) 567-574
-
(1999)
J. Leukoc. Biol.
, vol.66
, pp. 567-574
-
-
Li, Q.X.1
Fuller, S.J.2
Beyreuther, K.3
Masters, C.L.4
-
19
-
-
35648929821
-
Urea-based two-dimensional electrophoresis of β-amyloid peptides in human plasma: evidence for novel Abeta species
-
Maler J.M., Klafki H.W., Paul S., Spitzer P., Groemer T.W., Henkel A.W., Esselmann H., Lewczuk P., Kornhuber J., and Wiltfang J. Urea-based two-dimensional electrophoresis of β-amyloid peptides in human plasma: evidence for novel Abeta species. Proteomics 7 (2007) 3815-3820
-
(2007)
Proteomics
, vol.7
, pp. 3815-3820
-
-
Maler, J.M.1
Klafki, H.W.2
Paul, S.3
Spitzer, P.4
Groemer, T.W.5
Henkel, A.W.6
Esselmann, H.7
Lewczuk, P.8
Kornhuber, J.9
Wiltfang, J.10
-
20
-
-
0028956288
-
Extracellular matrix influences the biogenesis of amyloid precursor protein in microglial cells
-
Mönning U., Sandbrink R., Weidemann A., Banati R.B., Masters C.L., and Beyreuther K. Extracellular matrix influences the biogenesis of amyloid precursor protein in microglial cells. J. Biol. Chem. 270 (1995) 7104-7110
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 7104-7110
-
-
Mönning, U.1
Sandbrink, R.2
Weidemann, A.3
Banati, R.B.4
Masters, C.L.5
Beyreuther, K.6
-
21
-
-
30344448543
-
A dynamic relationship between intracellular and extracellular pools of Abeta
-
Oddo S., Caccamo A., Smith I.F., Green K.N., and LaFerla F.M. A dynamic relationship between intracellular and extracellular pools of Abeta. Am. J. Pathol. 168 (2006) 184-194
-
(2006)
Am. J. Pathol.
, vol.168
, pp. 184-194
-
-
Oddo, S.1
Caccamo, A.2
Smith, I.F.3
Green, K.N.4
LaFerla, F.M.5
-
22
-
-
33746809372
-
Physiological roles for amyloid beta peptides
-
Pearson H.A., and Peers C. Physiological roles for amyloid beta peptides. J. Physiol. 575 (2006) 5-10
-
(2006)
J. Physiol.
, vol.575
, pp. 5-10
-
-
Pearson, H.A.1
Peers, C.2
-
23
-
-
19944430034
-
Longer forms of amyloid beta protein: implications for the mechanism of intramembrane cleavage by gamma-secretase
-
Qi-Takahara Y., Morishima-Kawashima M., Tanimura Y., Dolios G., Hirotani N., Horikoshi Y., Kametani F., Maeda M., Saido T.C., Wang R., and Ihara Y. Longer forms of amyloid beta protein: implications for the mechanism of intramembrane cleavage by gamma-secretase. J. Neurosci. 25 (2005) 436-445
-
(2005)
J. Neurosci.
, vol.25
, pp. 436-445
-
-
Qi-Takahara, Y.1
Morishima-Kawashima, M.2
Tanimura, Y.3
Dolios, G.4
Hirotani, N.5
Horikoshi, Y.6
Kametani, F.7
Maeda, M.8
Saido, T.C.9
Wang, R.10
Ihara, Y.11
-
24
-
-
0018149190
-
Secretion of lysosomal hydrolases by stimulated and nonstimulated macrophages
-
Schnyder J., and Baggiolini M. Secretion of lysosomal hydrolases by stimulated and nonstimulated macrophages. J. Exp. Med. 148 (1978) 435-450
-
(1978)
J. Exp. Med.
, vol.148
, pp. 435-450
-
-
Schnyder, J.1
Baggiolini, M.2
-
25
-
-
0029933153
-
The role of APP processing and trafficking pathways in the formation of amyloid β-protein
-
Selkoe D.J., Yamazaki T., Citron M., Podlisny M.B., Koo E.H., Teplow D.B., and Haass C. The role of APP processing and trafficking pathways in the formation of amyloid β-protein. Ann. N.Y. Acad. Sci. 777 (1996) 57-64
-
(1996)
Ann. N.Y. Acad. Sci.
, vol.777
, pp. 57-64
-
-
Selkoe, D.J.1
Yamazaki, T.2
Citron, M.3
Podlisny, M.B.4
Koo, E.H.5
Teplow, D.B.6
Haass, C.7
-
26
-
-
34250328818
-
Pathological activity of familial Alzheimer's disease-associated mutant presenilin can be executed by six different γ-secretase complexes
-
Shirotani K., Tomioka M., Kremmer E., Haass C., and Steiner H. Pathological activity of familial Alzheimer's disease-associated mutant presenilin can be executed by six different γ-secretase complexes. Neurobiol. Dis. 27 (2007) 102-107
-
(2007)
Neurobiol. Dis.
, vol.27
, pp. 102-107
-
-
Shirotani, K.1
Tomioka, M.2
Kremmer, E.3
Haass, C.4
Steiner, H.5
-
27
-
-
33645296845
-
Amyloid precursor protein cross-linking stimulates beta amyloid production and pro-inflammatory cytokine release in monocytic lineage cells
-
Sondag C.M., and Combs C.K. Amyloid precursor protein cross-linking stimulates beta amyloid production and pro-inflammatory cytokine release in monocytic lineage cells. J. Neurochem. 97 (2006) 449-461
-
(2006)
J. Neurochem.
, vol.97
, pp. 449-461
-
-
Sondag, C.M.1
Combs, C.K.2
-
28
-
-
4444323422
-
Cells of monocyte/microglial lineage are involved in both microvessel amyloidosis and fibrillar plaque formation in APPsw tg mice
-
Wegiel J., Imaki H., Wang K.C., Wegiel J., and Rubenstein R. Cells of monocyte/microglial lineage are involved in both microvessel amyloidosis and fibrillar plaque formation in APPsw tg mice. Brain Res. 1022 (2004) 19-29
-
(2004)
Brain Res.
, vol.1022
, pp. 19-29
-
-
Wegiel, J.1
Imaki, H.2
Wang, K.C.3
Wegiel, J.4
Rubenstein, R.5
-
29
-
-
18444393054
-
Highly conserved and disease-specific patterns of carboxyterminally truncated Aβ peptides 1-37/38/39 in addition to 1-40/42 in Alzheimer's disease and in patients with chronic neuroinflammation
-
Wiltfang J., Esselmann H., Bibl M., Smirnov A., Otto M., Paul S., Schmidt B., Klafki H.W., Maler M., Dyrks T., Bienert M., Beyermann M., Rüther E., and Kornhuber J. Highly conserved and disease-specific patterns of carboxyterminally truncated Aβ peptides 1-37/38/39 in addition to 1-40/42 in Alzheimer's disease and in patients with chronic neuroinflammation. J. Neurochem. 81 (2002) 481-496
-
(2002)
J. Neurochem.
, vol.81
, pp. 481-496
-
-
Wiltfang, J.1
Esselmann, H.2
Bibl, M.3
Smirnov, A.4
Otto, M.5
Paul, S.6
Schmidt, B.7
Klafki, H.W.8
Maler, M.9
Dyrks, T.10
Bienert, M.11
Beyermann, M.12
Rüther, E.13
Kornhuber, J.14
-
30
-
-
0035900774
-
Elevation of β-amyloid peptide 2-42 in sporadic and familial Alzheimer's disease and its generation in PS1 knockout cells
-
Wiltfang J., Esselmann H., Cupers P., Neumann M., Kretzschmar H., Beyermann M., Schleuder D., Jahn H., Rüther E., Kornhuber J., Annaert W., De Strooper B., and Saftig P. Elevation of β-amyloid peptide 2-42 in sporadic and familial Alzheimer's disease and its generation in PS1 knockout cells. J. Biol. Chem. 276 (2001) 42645-42657
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 42645-42657
-
-
Wiltfang, J.1
Esselmann, H.2
Cupers, P.3
Neumann, M.4
Kretzschmar, H.5
Beyermann, M.6
Schleuder, D.7
Jahn, H.8
Rüther, E.9
Kornhuber, J.10
Annaert, W.11
De Strooper, B.12
Saftig, P.13
-
31
-
-
0026685656
-
Ultrastructural studies of the cells forming amyloid in the cortical vessel wall in Alzheimer's disease
-
Wisniewski H.M., Wegiel J., Wang K.C., and Lach B. Ultrastructural studies of the cells forming amyloid in the cortical vessel wall in Alzheimer's disease. Acta Neuropathol. 84 (1992) 117-127
-
(1992)
Acta Neuropathol.
, vol.84
, pp. 117-127
-
-
Wisniewski, H.M.1
Wegiel, J.2
Wang, K.C.3
Lach, B.4
-
32
-
-
34548179335
-
γ-Secretase substrate concentration modulates the Aβ42/Aβ40 ratio: implications for Alzheimer disease
-
Yin Y.I., Bassit B., Zhu L., Yang X., Wang C., and Li Y.M. γ-Secretase substrate concentration modulates the Aβ42/Aβ40 ratio: implications for Alzheimer disease. J. Biol. Chem. 282 (2007) 23639-23644
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 23639-23644
-
-
Yin, Y.I.1
Bassit, B.2
Zhu, L.3
Yang, X.4
Wang, C.5
Li, Y.M.6
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