Metformin protects the brain against the oxidative imbalance promoted by type 2 diabetes

Medicinal Chemistry

Volumn 4, Issue 4, 2008, Pages 358-364

  Correia, Sónia ^b,c   Carvalho, Cristina ^b,c   Santos, Maria S ^a,b   Proença, Teresa ^a,c   Nunes, Elsa ^a,d   Duarte, Ana I ^a,b   Monteiro, Pedro ^c   Seiça, Raquel ^a,d   Oliveira, Catarina R ^a,d   Moreira, Paula I ^a,d  

^a UNIVERSITY OF COIMBRA   (Portugal)

^b UNIVERSITY OF COIMBRA   (Portugal)

^c CENTRO HOSPITALAR E UNIVERSITÁRIO DE COIMBRA   (Portugal)

^d UNIVERSITY OF COIMBRA   (Portugal)

Author keywords

Brain; Metformin; Oxidative stress; Type 2 diabetes

Indexed keywords

ALPHA TOCOPHEROL; CARBONYL DERIVATIVE; FREE RADICAL; GLUCOSE; GLUTATHIONE; GLUTATHIONE DISULFIDE; GLUTATHIONE PEROXIDASE; GLUTATHIONE REDUCTASE; HYDROGEN PEROXIDE; INSULIN; MALONALDEHYDE; MANGANESE SUPEROXIDE DISMUTASE; METFORMIN; THIOBARBITURIC ACID REACTIVE SUBSTANCE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ARTICLE; BRAIN HOMOGENATE; BRAIN PROTECTION; CONTROLLED STUDY; DIABETIC NEUROPATHY; DRUG EFFECT; GLUCOSE BLOOD LEVEL; GOTO KAKIZAKI RAT; HYPERGLYCEMIA; INSULIN BLOOD LEVEL; LIPID PEROXIDATION; MALE; NEUROPROTECTION; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; RAT; WISTAR RAT;

ANIMALS; BLOOD GLUCOSE; BODY WEIGHT; BRAIN; DIABETES MELLITUS, TYPE 2; GLUTATHIONE; HYDROGEN PEROXIDE; MALE; METFORMIN; OXIDATION-REDUCTION; OXIDATIVE STRESS; PROTEINS; RATS;

EID: 50049125341     PISSN: 15734064     EISSN: None     Source Type: Journal    
DOI: 10.2174/157340608784872299     Document Type: Article

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