A 19F-NMR approach using reporter molecule pairs to assess β-galactosidase in human xenograft tumors in vivo

NMR in Biomedicine

Volumn 21, Issue 7, 2008, Pages 704-712

  Yu, Jian Xin ^a   Kodibagkar, Vikram D ^a   Liu, Li ^a   Mason, Ralph P ^a  

^a UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

Author keywords

galactosidase; 19F NMR; Breast cancer; lacZ; pH; Reporter molecules

Indexed keywords

BIOACTIVITY; GENE EXPRESSION; GENETIC ENGINEERING; NUCLEIC ACIDS; SUGAR (SUCROSE);

19F NMR; BREAST CANCER; GALACTOSIDASE; GENE THERAPIES; HUMAN PROSTATE; IN-VIVO; LACZ; NON-INVASIVE; PH; REPORTER MOLECULES; TARGET TISSUES; TUMOR XENOGRAFTS;

HEALTH;

1,2 FLUORO 1,4 NITROPHENYL BETA DEXTRO GALACTOPYRANOSIDE; BETA GALACTOSIDASE; PYRANOSIDE; 2 FLUORO 4 NITROPHENYL GALACTOPYRANOSIDE; 2-FLUORO-4-NITROPHENYL GALACTOPYRANOSIDE; 4 NITROPHENYLGALACTOSIDE; FLUORINE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BREAST CANCER; CELL STRAIN MCF 7; CONTROLLED STUDY; DISEASE ACTIVITY; ENZYME ACTIVITY; ENZYME ANALYSIS; ENZYME SPECIFICITY; FLUORINE NUCLEAR MAGNETIC RESONANCE; GENE EXPRESSION; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; HYDROLYSIS; IN VIVO STUDY; MOUSE; NONHUMAN; NUDE MOUSE; PRIORITY JOURNAL; REPORTER GENE; TRANSGENE; TUMOR XENOGRAFT; WILD TYPE; ANIMAL; BREAST TUMOR; CANCER TRANSPLANTATION; ENZYMOLOGY; METABOLISM; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PATHOLOGY; TIME; TUMOR CELL LINE; XENOGRAFT;

MUS; MUS MUSCULUS;

ANIMALS; BETA-GALACTOSIDASE; BREAST NEOPLASMS; CELL LINE, TUMOR; FLUORINE; HUMANS; HYDROLYSIS; MAGNETIC RESONANCE SPECTROSCOPY; MICE; MICE, NUDE; NEOPLASM TRANSPLANTATION; NITROPHENYLGALACTOSIDES; SUBSTRATE SPECIFICITY; TIME FACTORS; TRANSPLANTATION, HETEROLOGOUS;

EID: 50049116089     PISSN: 09523480     EISSN: 10991492     Source Type: Journal    
DOI: 10.1002/nbm.1244     Document Type: Article

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