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58149180688
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An analogous allyltitanium intermediate has been postulated for the cyclopropanation of N,N-dialkylamides with 1,3-dienes; see ref 6
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An analogous allyltitanium intermediate has been postulated for the cyclopropanation of N,N-dialkylamides with 1,3-dienes; see ref 6.
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24
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33845378644
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An alternative mechanism, similar to the vinylcyclopropane-cyclopentene rearrangement can also be considered; see, for example: (a) Danheiser, R. L, Bronson, J. J, Okano, K. J. Am. Chem. Soc. 1985, 107, 4579
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An alternative mechanism, similar to the vinylcyclopropane-cyclopentene rearrangement can also be considered; see, for example: (a) Danheiser, R. L.; Bronson, J. J.; Okano, K. J. Am. Chem. Soc. 1985, 107, 4579.
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0029045355
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26
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58149182087
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The relative stereochemistry of 4a was elucidated by NOE.
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The relative stereochemistry of 4a was elucidated by NOE.
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27
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58149198894
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Similar results were obtained by applying the ligand-exchange procedure
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Similar results were obtained by applying the ligand-exchange procedure.
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58149193930
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See the Supporting Information
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See the Supporting Information.
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29
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35649020765
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For some synthetic uses of cyclopropylamines, see: a
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Vinylcyclopropanes are involved in a number of ring expansion and cycloaddition reactions; see, for example: (a) Wender, P. A.; Gamber, G. G.; Williams, T. J. In Modern Rhodium-Catalyzed Organic Reactions; Evans, P. A., Ed.; Wiley-VCH: Weinheim, 2005; Chapter 13.
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Vinylcyclopropanes are involved in a number of ring expansion and cycloaddition reactions; see, for example: (a) Wender, P. A.; Gamber, G. G.; Williams, T. J. In Modern Rhodium-Catalyzed Organic Reactions; Evans, P. A., Ed.; Wiley-VCH: Weinheim, 2005; Chapter 13.
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