The effects of acute exercise-induced cortisol on CCR2 expression on human monocytes

Brain, Behavior, and Immunity

Volumn 22, Issue 7, 2008, Pages 1066-1071

  Okutsu, Mitsuharu ^a   Suzuki, Katsuhiko ^a   Ishijima, Toshimichi ^a   Peake, Jonathan ^b   Higuchi, Mitsuru ^a  

^a WASEDA UNIVERSITY   (Japan)

^b UNIVERSITY OF QUEENSLAND   (Australia)

Author keywords

Cell migration; Chemokine receptor; Cortisol; Exercise; Physical stress

Indexed keywords

ADRENALIN; CHEMOKINE RECEPTOR CCR2; HYDROCORTISONE; MIFEPRISTONE; MONOCYTE CHEMOTACTIC PROTEIN 1; NORADRENALIN;

ADULT; ARTICLE; BLOOD SAMPLING; CELL MIGRATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; EXERCISE; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; IN VITRO STUDY; INCUBATION TIME; MALE; MEMBRANE FILTER; MONOCYTE; NORMAL HUMAN; OXYGEN CONSUMPTION; PERIPHERAL BLOOD MONONUCLEAR CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; STRESS;

ADULT; ANTIGENS, CD14; CELLS, CULTURED; DOSE-RESPONSE RELATIONSHIP, DRUG; EPINEPHRINE; EXERCISE; HEART RATE; HORMONE ANTAGONISTS; HUMANS; HYDROCORTISONE; MALE; MIFEPRISTONE; MONOCYTES; NOREPINEPHRINE; PULMONARY GAS EXCHANGE; RECEPTORS, CCR2; STRESS; TIME FACTORS;

EID: 50049103129     PISSN: 08891591     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbi.2008.03.006     Document Type: Article

References (38)

1. Barlic J., and Murphy P.M. Chemokine regulation of atherosclerosis. J. Leukoc. Biol. (2007)
2. Brodmerkel C.M., Huber R., Covington M., Diamond S., Hall L., Collins R., Leffet L., Gallagher K., Feldman P., Collier P., Stow M., Gu X., Baribaud F., Shin N., Thomas B., Burn T., Hollis G., Yeleswaram S., Solomon K., Friedman S., Wang A., Xue C.B., Newton R.C., Scherle P., and Vaddi K. Discovery and pharmacological characterization of a novel rodent-active CCR2 antagonist, INCB3344. J. Immunol. 175 (2005) 5370-5378
3. Calcagni E., and Elenkov I. Stress system activity, innate and T helper cytokines, and susceptibility to immune-related diseases. Ann. N. Y. Acad. Sci. 1069 (2006) 62-76
4. Capers Q.t., Alexander R.W., Lou P., De Leon H., Wilcox J.N., Ishizaka N., Howard A.B., and Taylor W.R. Monocyte chemoattractant protein-1 expression in aortic tissues of hypertensive rats. Hypertension 30 (1997) 1397-1402
5. Contreras-Shannon V., Ochoa O., Reyes-Reyna S.M., Sun D., Michalek J.E., Kuziel W.A., McManus L.M., and Shireman P.K. Fat accumulation with altered inflammation and regeneration in skeletal muscle of CCR2-/- mice following ischemic injury. Am. J. Physiol. Cell Physiol. 292 (2007) C953-C967
6. Dhabhar F.S. Stress-induced augmentation of immune function---the role of stress hormones, leukocyte trafficking, and cytokines. Brain Behav. Immun. 16 (2002) 785-798
7. Dhabhar F.S., and McEwen B.S. Enhancing versus suppressive effects of stress hormones on skin immune function. Proc. Natl. Acad. Sci. USA 96 (1999) 1059-1064
8. Fehrenbach E., and Schneider M.E. Trauma-induced systemic inflammatory response versus exercise-induced immunomodulatory effects. Sports Med. 36 (2006) 373-384
9. Han K.H., Hong K.H., Park J.H., Ko J., Kang D.H., Choi K.J., Hong M.K., Park S.W., and Park S.J. C-reactive protein promotes monocyte chemoattractant protein-1-mediated chemotaxis through upregulating CC chemokine receptor 2 expression in human monocytes. Circulation 109 (2004) 2566-2571
10. Kumari M., Grahame-Clarke C., Shanks N., Marmot M., Lightman S., and Vallance P. Chronic stress accelerates atherosclerosis in the apolipoprotein E deficient mouse. Stress 6 (2003) 297-299
11. Li Y.S., Shyy Y.J., Wright J.G., Valente A.J., Cornhill J.F., and Kolattukudy P.E. The expression of monocyte chemotactic protein (MCP-1) in human vascular endothelium in vitro and in vivo. Mol. Cell. Biochem. 126 (1993) 61-68
12. Miyaura H., and Iwata M. Direct and indirect inhibition of Th1 development by progesterone and glucocorticoids. J. Immunol. 168 (2002) 1087-1094
13. Monder C., Miroff Y., Marandici A., and Hardy M.P. 11 Beta-Hydroxysteroid dehydrogenase alleviates glucocorticoid-mediated inhibition of steroidogenesis in rat Leydig cells. Endocrinology 134 (1994) 1199-1204
14. Nielsen H.G., and Lyberg T. Long-distance running modulates the expression of leucocyte and endothelial adhesion molecules. Scand. J. Immunol. 60 (2004) 356-362
15. Nieman D.C., Davis J.M., Henson D.A., Gross S.J., Dumke C.L., Utter A.C., Vinci D.M., Carson J.A., Brown A., McAnulty S.R., McAnulty L.S., and Triplett N.T. Muscle cytokine mRNA changes after 25 h of cycling: influence of carbohydrate. Med. Sci. Sports Exerc. 37 (2005) 1283-1290
16. Nieman D.C., Henson D.A., Dumke C.L., Oley K., McAnulty S.R., Davis J.M., Murphy E.A., Utter A.C., Lind R.H., McAnulty L.S., and Morrow J.D. Ibuprofen use, endotoxemia, inflammation, and plasma cytokines during ultramarathon competition. Brain Behav. Immun. 20 (2006) 578-584
17. Okutsu M., Ishii K., Niu K.J., and Nagatomi R. Cortisol-induced CXCR4 augmentation mobilizes T lymphocytes after acute physical stress. Am. J. Physiol. Regul. Integr. Comp. Physiol. 288 (2005) R591-R599
18. Ostrowski K., Rohde T., Asp S., Schjerling P., and Pedersen B.K. Pro- and anti-inflammatory cytokine balance in strenuous exercise in humans. J. Physiol. 515 Pt 1 (1999) 287-291
19. Passlick B., Flieger D., and Ziegler-Heitbrock HWL. Identification and characterization of a novel monocyte subpopulation in human peripheral blood. Blood 74 (1989) 2527-2534
20. Peake J.M., Suzuki K., Hordern M., Wilson G., Nosaka K., and Coombes J.S. Plasma cytokine changes in relation to exercise intensity and muscle damage. Eur. J. Appl. Physiol. 95 (2005) 514-521
21. Pedersen B.K., and Hoffman-Goetz L. Exercise and the immune system: regulation, integration, and adaptation. Physiol. Rev. 80 (2000) 1055-1081
22. Penton-Rol G., Cota M., Polentarutti N., Luini W., Bernasconi S., Borsatti A., Sica A., LaRosa G.J., Sozzani S., Poli G., and Mantovani A. Up-regulation of CCR2 chemokine receptor expression and increased susceptibility to the multitropic HIV strain 896 in monocytes exposed to glucocorticoid hormones. J. Immunol. 163 (1999) 3524-3529
23. Penton-Rol G., Polentarutti N., Luini W., Borsatti A., Mancinelli R., Sica A., Sozzani S., and Mantovani A. Selective inhibition of expression of the chemokine receptor CCR2 in human monocytes by IFN-gamma. J. Immunol. 160 (1998) 3869-3873
24. Pettersson A., Sabirsh A., Bristulf J., Kidd-Ljunggren K., Ljungberg B., Owman C., and Karlsson U. Pro- and anti-inflammatory substances modulate expression of the leukotriene B4 receptor, BLT1, in human monocytes. J. Leukoc. Biol. 77 (2005) 1018-1025
25. Rollins B.J. Monocyte chemoattractant protein 1: a potential regulator of monocyte recruitment in inflammatory disease. Mol. Med. Today 2 (1996) 198-204
26. Shinkai S., Watanabe S., Asai H., and Shek P.N. Cortisol response to exercise and post-exercise suppression of blood lymphocyte subset counts. Int. J. Sports Med. 17 (1996) 597-603
27. Shireman P.K., Contreras-Shannon V., Ochoa O., Karia B.P., Michalek J.E., and McManus L.M. MCP-1 deficiency causes altered inflammation with impaired skeletal muscle regeneration. J. Leukoc. Biol. 81 (2007) 775-785
28. Sica A., Saccani A., Borsatti A., Power C.A., Wells T.N., Luini W., Polentarutti N., Sozzani S., and Mantovani A. Bacterial lipopolysaccharide rapidly inhibits expression of C-C chemokine receptors in human monocytes. J. Exp. Med. 185 (1997) 969-974
29. Siiteri P.K., and Simberg N.H. Changing concepts of active androgens in blood. Clin. Endocrinol. Metab. 15 (1986) 247-258
30. Sozzani S., Ghezzi S., Iannolo G., Luini W., Borsatti A., Polentarutti N., Sica A., Locati M., Mackay C., Wells T.N., Biswas P., Vicenzi E., Poli G., and Mantovani A. Interleukin 10 increases CCR5 expression and HIV infection in human monocytes. J. Exp. Med. 187 (1998) 439-444
31. Spencer R.L., Young E.A., Choo P.H., and McEwen B.S. Adrenal steroid type I and type II receptor binding: estimates of in vivo receptor number, occupancy, and activation with varying level of steroid. Brain Res. 514 (1990) 37-48
32. Starkie R.L., Rolland J., and Febbraio M.A. Effect of adrenergic blockade on lymphocyte cytokine production at rest and during exercise. Am. J. Physiol. Cell Physiol. 281 (2001) C1233-C1240
33. Steensberg A., Keller C., Hillig T., Frosig C., Wojtaszewski J.F., Pedersen B.K., Pilegaard H., and Sander M. Nitric oxide production is a proximal signaling event controlling exercise-induced mRNA expression in human skeletal muscle. FASEB J. 21 (2007) 2683-2694
34. Steppich B., Dayyani F., Gruber R., Lorenz R., Mack M., and Ziegler-Heitbrock H.W. Selective mobilization of CD14(+)CD16(+) monocytes by exercise. Am. J. Physiol. Cell Physiol. 279 (2000) C578-C586
35. Suzuki K., Nakaji S., Yamada M., Totsuka M., Sato K., and Sugawara K. Systemic inflammatory response to exhaustive exercise. Cytokine kinetics. Exerc. Immunol. Rev. 8 (2002) 6-48
36. Svec F. Biopotency of corticosterone and dexamethasone in causing glucocorticoid receptor downregulation. J. Steroid Biochem. 23 (1985) 669-671
37. Warren G.L., Hulderman T., Mishra D., Gao X., Millecchia L., O'Farrell L., Kuziel W.A., and Simeonova P.P. Chemokine receptor CCR2 involvement in skeletal muscle regeneration. FASEB J. 19 (2005) 413-415
38. Warren G.L., O'Farrell L., Summan M., Hulderman T., Mishra D., Luster M.I., Kuziel W.A., and Simeonova P.P. Role of CC chemokines in skeletal muscle functional restoration after injury. Am. J. Physiol. Cell Physiol. 286 (2004) C1031-C1036