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Volumn 250, Issue 2-3, 2008, Pages 132-142

Effect of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) on heme oxygenase-1, biliverdin IXα reductase and δ-aminolevulinic acid synthetase 1 in rats with wild-type or variant AH receptor

Author keywords

Aminolevulinic acid synthetase; 2,3,7,8 Tetrachlorodibenzo p dioxin; Biliverdin reductase; Heme metabolism; Heme oxygenase

Indexed keywords

2,3,7,8 TETRACHLORODIBENZO PARA DIOXIN; 5 AMINOLEVULINATE SYNTHASE; AROMATIC HYDROCARBON RECEPTOR; BILIRUBIN; BILIVERDIN; BILIVERDIN IXALPHAA REDUCTASE; DELTA AMINOLEVULINIC ACID SYNTHETHASE 1; HEME; HEME OXYGENASE 1; ISOENZYME; MESSENGER RNA; UNCLASSIFIED DRUG;

EID: 49849103986     PISSN: 0300483X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tox.2008.06.014     Document Type: Article
Times cited : (18)

References (49)
  • 1
    • 0141885079 scopus 로고    scopus 로고
    • Transcriptional regulation of the heme oxygenase-1 gene via the stress response element pathway
    • Alam J., and Cook J.L. Transcriptional regulation of the heme oxygenase-1 gene via the stress response element pathway. Curr. Pharm. Des. 9 (2003) 2499-2511
    • (2003) Curr. Pharm. Des. , vol.9 , pp. 2499-2511
    • Alam, J.1    Cook, J.L.2
  • 2
    • 0022914695 scopus 로고
    • Characterization of two heme oxygenase isoforms in rat spleen: comparison with the hematin-induced and constitutive isoforms of the liver
    • Braggins P.E., Trakshel G.M., Kutty R.K., and Maines M.D. Characterization of two heme oxygenase isoforms in rat spleen: comparison with the hematin-induced and constitutive isoforms of the liver. Biochem. Biophys. Res. Commun. 141 (1986) 528-533
    • (1986) Biochem. Biophys. Res. Commun. , vol.141 , pp. 528-533
    • Braggins, P.E.1    Trakshel, G.M.2    Kutty, R.K.3    Maines, M.D.4
  • 3
    • 0015328372 scopus 로고
    • Enzymatic functions as targets of the toxicity of "Dioxin" (2,3,7,8-tetrachlorodibenzo-p-dioxin)
    • Buu-Hoï N.P., Chanh P.H., Sesqué G., Azum-Gelade M.C., and Saint-Ruf G. Enzymatic functions as targets of the toxicity of "Dioxin" (2,3,7,8-tetrachlorodibenzo-p-dioxin). Naturwissenschaften 59 (1972) 173-174
    • (1972) Naturwissenschaften , vol.59 , pp. 173-174
    • Buu-Hoï, N.P.1    Chanh, P.H.2    Sesqué, G.3    Azum-Gelade, M.C.4    Saint-Ruf, G.5
  • 4
    • 0023628090 scopus 로고
    • Effects of chlorinated organics on intermediates in the heme pathway and on uroporphyrinogen decarboxylase
    • Cantoni L., Rizzardini M., Graziani A., Carugo C., and Garattini S. Effects of chlorinated organics on intermediates in the heme pathway and on uroporphyrinogen decarboxylase. Ann. N.Y. Acad. Sci. 514 (1987) 128-140
    • (1987) Ann. N.Y. Acad. Sci. , vol.514 , pp. 128-140
    • Cantoni, L.1    Rizzardini, M.2    Graziani, A.3    Carugo, C.4    Garattini, S.5
  • 5
    • 12244274057 scopus 로고
    • Effect of butylated hydroxytoluene (BHT) and butylated hydroxyanisole (BHA) on carbon tetrachloride and TCDD hepatotoxicity
    • Choe S.Y., and Yang K.H. Effect of butylated hydroxytoluene (BHT) and butylated hydroxyanisole (BHA) on carbon tetrachloride and TCDD hepatotoxicity. Korean Biochem. J. 16 (1983) 315-321
    • (1983) Korean Biochem. J. , vol.16 , pp. 315-321
    • Choe, S.Y.1    Yang, K.H.2
  • 6
    • 0028510057 scopus 로고
    • Dioxin-dependent, DNA sequence-specific binding of a multiprotein complex containing the Ah receptor
    • Elferink C.J., and Whitlock J.P. Dioxin-dependent, DNA sequence-specific binding of a multiprotein complex containing the Ah receptor. Receptor 4 (1994) 157-173
    • (1994) Receptor , vol.4 , pp. 157-173
    • Elferink, C.J.1    Whitlock, J.P.2
  • 8
    • 0020053557 scopus 로고
    • Induction of porphyria in the rat by chronic versus acute exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin
    • Goldstein J.A., Linko P., and Bergman H. Induction of porphyria in the rat by chronic versus acute exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin. Biochem. Pharmacol. 31 (1982) 1607-1613
    • (1982) Biochem. Pharmacol. , vol.31 , pp. 1607-1613
    • Goldstein, J.A.1    Linko, P.2    Bergman, H.3
  • 9
    • 0014027226 scopus 로고
    • The induction in vitro of the synthesis of δ-aminolevulinic acid synthetase in chemical porphyria: a response to certain drugs, sex hormones, and foreign chemicals
    • Granick S. The induction in vitro of the synthesis of δ-aminolevulinic acid synthetase in chemical porphyria: a response to certain drugs, sex hormones, and foreign chemicals. J. Biol. Chem. 241 (1966) 1359-1375
    • (1966) J. Biol. Chem. , vol.241 , pp. 1359-1375
    • Granick, S.1
  • 10
    • 0037462728 scopus 로고    scopus 로고
    • Inhibitory effect of AP-1 complex on 5-aminolevulinate synthase gene expression through sequestration of cAMP-response element protein (CRE)-binding protein (CBP) coactivator
    • Guberman A.S., Scassa M.E., Giono L.E., Varone C.L., and Canepa E.T. Inhibitory effect of AP-1 complex on 5-aminolevulinate synthase gene expression through sequestration of cAMP-response element protein (CRE)-binding protein (CBP) coactivator. J. Biol. Chem. 278 (2003) 2317-2326
    • (2003) J. Biol. Chem. , vol.278 , pp. 2317-2326
    • Guberman, A.S.1    Scassa, M.E.2    Giono, L.E.3    Varone, C.L.4    Canepa, E.T.5
  • 11
    • 0026045762 scopus 로고
    • Heme regulates hepatic 5-aminolevulinate synthase mRNA expression by decreasing mRNA half-life and not by altering its rate of transcription
    • Hamilton J.W., Bement W.J., Sinclair P.R., Sinclair J.F., Alcedo J.A., and Wetterhahn K.E. Heme regulates hepatic 5-aminolevulinate synthase mRNA expression by decreasing mRNA half-life and not by altering its rate of transcription. Arch. Biochem. Biophys. 289 (1991) 387-392
    • (1991) Arch. Biochem. Biophys. , vol.289 , pp. 387-392
    • Hamilton, J.W.1    Bement, W.J.2    Sinclair, P.R.3    Sinclair, J.F.4    Alcedo, J.A.5    Wetterhahn, K.E.6
  • 12
    • 0017293972 scopus 로고
    • 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD): results of a 13-week oral toxicity study in rats
    • Kociba R.J., Keeler P.A., Park C.N., and Gehring P.J. 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD): results of a 13-week oral toxicity study in rats. Toxicol. Appl. Pharmacol. 35 (1976) 553-574
    • (1976) Toxicol. Appl. Pharmacol. , vol.35 , pp. 553-574
    • Kociba, R.J.1    Keeler, P.A.2    Park, C.N.3    Gehring, P.J.4
  • 13
    • 0842308115 scopus 로고    scopus 로고
    • Primary structure and inducibility by 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) of aryl hydrocarbon receptor repressor in a TCDD-sensitive and a TCDD-resistant rat strain
    • Korkalainen M., Tuomisto J., and Pohjanvirta R. Primary structure and inducibility by 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) of aryl hydrocarbon receptor repressor in a TCDD-sensitive and a TCDD-resistant rat strain. Biochem. Biophys. Res. Commun. 315 (2004) 123-131
    • (2004) Biochem. Biophys. Res. Commun. , vol.315 , pp. 123-131
    • Korkalainen, M.1    Tuomisto, J.2    Pohjanvirta, R.3
  • 14
    • 12444312577 scopus 로고    scopus 로고
    • Effect of TCDD on mRNA expression of genes encoding bHLH/PAS proteins in rat hypothalamus
    • Korkalainen M., Lindén J., Tuomisto J., and Pohjanvirta R. Effect of TCDD on mRNA expression of genes encoding bHLH/PAS proteins in rat hypothalamus. Toxicology 208 (2005) 1-11
    • (2005) Toxicology , vol.208 , pp. 1-11
    • Korkalainen, M.1    Lindén, J.2    Tuomisto, J.3    Pohjanvirta, R.4
  • 15
    • 0032856531 scopus 로고    scopus 로고
    • The oxidoreductase, biliverdin reductase, is induced in human renal carcinoma-pH and cofactor-specific increase in activity
    • Maines M.D., Mayer R.D., Erturk E., Huang T.J., and Disantagnese A. The oxidoreductase, biliverdin reductase, is induced in human renal carcinoma-pH and cofactor-specific increase in activity. J. Urol. 162 (1999) 1467-1472
    • (1999) J. Urol. , vol.162 , pp. 1467-1472
    • Maines, M.D.1    Mayer, R.D.2    Erturk, E.3    Huang, T.J.4    Disantagnese, A.5
  • 17
    • 0029123921 scopus 로고
    • The structure, organization and differential expression of the rat gene encoding biliverdin reductase
    • McCoubrey W.K., Cooklis M.A., and Maines M.D. The structure, organization and differential expression of the rat gene encoding biliverdin reductase. Gene 160 (1995) 235-240
    • (1995) Gene , vol.160 , pp. 235-240
    • McCoubrey, W.K.1    Cooklis, M.A.2    Maines, M.D.3
  • 18
    • 0035126828 scopus 로고    scopus 로고
    • Turning green to gold
    • McDonagh A.F. Turning green to gold. Nat. Struct. Biol. 8 (2001) 198-200
    • (2001) Nat. Struct. Biol. , vol.8 , pp. 198-200
    • McDonagh, A.F.1
  • 19
    • 12244313837 scopus 로고
    • Hepatotoxicants elevate serum bilirubin by increasing formation not decreasing elimination of bilirubin.
    • (Abstract)
    • Mitchell D.Y., Madhu C., and Klaassen C.D. Hepatotoxicants elevate serum bilirubin by increasing formation not decreasing elimination of bilirubin. Toxicol. Sci. 10 61 (Suppl.) (1990) (Abstract)
    • (1990) Toxicol. Sci. , vol.10 , Issue.61 SUPPL.
    • Mitchell, D.Y.1    Madhu, C.2    Klaassen, C.D.3
  • 20
    • 0035983247 scopus 로고    scopus 로고
    • Heme oxygenase-1: the "emerging molecule" has arrived
    • Morse D., and Choi A.M. Heme oxygenase-1: the "emerging molecule" has arrived. Am. J. Respir. Cell Mol. Biol. 27 (2002) 8-16
    • (2002) Am. J. Respir. Cell Mol. Biol. , vol.27 , pp. 8-16
    • Morse, D.1    Choi, A.M.2
  • 22
    • 34247556427 scopus 로고    scopus 로고
    • Differences in acute toxicity syndromes of 2,3,7,8-tetrachlorodibenzo-p-dioxin and 1,2,3,4,7,8-hexachlorodibenzo-p-dioxin in rats
    • Niittynen M., Simanainen U., Syrjälä P., Pohjanvirta R., Viluksela M., Tuomisto J., and Tuomisto J.T. Differences in acute toxicity syndromes of 2,3,7,8-tetrachlorodibenzo-p-dioxin and 1,2,3,4,7,8-hexachlorodibenzo-p-dioxin in rats. Toxicology 235 (2007) 39-51
    • (2007) Toxicology , vol.235 , pp. 39-51
    • Niittynen, M.1    Simanainen, U.2    Syrjälä, P.3    Pohjanvirta, R.4    Viluksela, M.5    Tuomisto, J.6    Tuomisto, J.T.7
  • 23
    • 34447530842 scopus 로고    scopus 로고
    • An aryl hydrocarbon receptor odyssey to the shores of toxicology: the Deichmann Lecture, International Congress of Toxicology-XI
    • Okey A.B. An aryl hydrocarbon receptor odyssey to the shores of toxicology: the Deichmann Lecture, International Congress of Toxicology-XI. Toxicol. Sci. 98 (2007) 5-38
    • (2007) Toxicol. Sci. , vol.98 , pp. 5-38
    • Okey, A.B.1
  • 24
    • 0018366715 scopus 로고
    • Depression of adenosine triphosphatase activities in isolated liver surface membranes of 2,3,7,8-tetrachlorodibenzo-p-dioxin-treated rats: correlation with effects on ouabain biliary excretion and bile flow
    • Peterson R.E., Madhukar B.V., Yang K.H., and Matsumura F. Depression of adenosine triphosphatase activities in isolated liver surface membranes of 2,3,7,8-tetrachlorodibenzo-p-dioxin-treated rats: correlation with effects on ouabain biliary excretion and bile flow. J. Pharmacol. Exp. Ther. 210 (1979) 275-282
    • (1979) J. Pharmacol. Exp. Ther. , vol.210 , pp. 275-282
    • Peterson, R.E.1    Madhukar, B.V.2    Yang, K.H.3    Matsumura, F.4
  • 25
    • 0025189637 scopus 로고
    • TCDD resistance is inherited as an autosomal dominant trait in the rat
    • Pohjanvirta R. TCDD resistance is inherited as an autosomal dominant trait in the rat. Toxicol. Lett. 50 (1990) 49-56
    • (1990) Toxicol. Lett. , vol.50 , pp. 49-56
    • Pohjanvirta, R.1
  • 26
    • 33644752604 scopus 로고    scopus 로고
    • Evaluation of various housekeeping genes for their applicability for normalization of mRNA expression in dioxin-treated rats
    • Pohjanvirta R., Niittynen M., Lindén J., Boutros P.C., Moffat I.D., and Okey A.B. Evaluation of various housekeeping genes for their applicability for normalization of mRNA expression in dioxin-treated rats. Chem. Biol. Interact. 160 (2006) 134-149
    • (2006) Chem. Biol. Interact. , vol.160 , pp. 134-149
    • Pohjanvirta, R.1    Niittynen, M.2    Lindén, J.3    Boutros, P.C.4    Moffat, I.D.5    Okey, A.B.6
  • 28
    • 0028588925 scopus 로고
    • Short-term toxicity of 2,3,7,8-tetrachlorodibenzo-p-dioxin in laboratory animals: effects, mechanisms, and animal models
    • Pohjanvirta R., and Tuomisto J. Short-term toxicity of 2,3,7,8-tetrachlorodibenzo-p-dioxin in laboratory animals: effects, mechanisms, and animal models. Pharmacol. Rev. 46 (1994) 483-549
    • (1994) Pharmacol. Rev. , vol.46 , pp. 483-549
    • Pohjanvirta, R.1    Tuomisto, J.2
  • 30
    • 0027257203 scopus 로고
    • Comparative acute lethality of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD), 1,2,3,7,8-pentachlorodibenzo-p-dioxin and 1,2,3,4,7,8-hexachlorodibenzo-p-dioxin in the most TCDD-susceptible and the most TCDD-resistant rat strain
    • Pohjanvirta R., Unkila M., and Tuomisto J. Comparative acute lethality of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD), 1,2,3,7,8-pentachlorodibenzo-p-dioxin and 1,2,3,4,7,8-hexachlorodibenzo-p-dioxin in the most TCDD-susceptible and the most TCDD-resistant rat strain. Pharmacol. Toxicol. 73 (1993) 52-56
    • (1993) Pharmacol. Toxicol. , vol.73 , pp. 52-56
    • Pohjanvirta, R.1    Unkila, M.2    Tuomisto, J.3
  • 32
    • 0031845222 scopus 로고    scopus 로고
    • Point mutation in intron sequence causes altered carboxyl-terminal structure in the aryl hydrocarbon receptor of the most 2,3,7,8-tetrachlorodibenzo-p-dioxin-resistant rat strain
    • Pohjanvirta R., Wong J.M., Li W., Harper P.A., Tuomisto J., and Okey A.B. Point mutation in intron sequence causes altered carboxyl-terminal structure in the aryl hydrocarbon receptor of the most 2,3,7,8-tetrachlorodibenzo-p-dioxin-resistant rat strain. Mol. Pharmacol. 54 (1998) 86-93
    • (1998) Mol. Pharmacol. , vol.54 , pp. 86-93
    • Pohjanvirta, R.1    Wong, J.M.2    Li, W.3    Harper, P.A.4    Tuomisto, J.5    Okey, A.B.6
  • 33
    • 0015911921 scopus 로고
    • 2,3,7,8-Tetrachlorodibenzo-p-dioxin: a potent inducer of δ-aminolevulinic acid synthetase
    • Poland A., and Glover E. 2,3,7,8-Tetrachlorodibenzo-p-dioxin: a potent inducer of δ-aminolevulinic acid synthetase. Science 179 (1973) 476-477
    • (1973) Science , vol.179 , pp. 476-477
    • Poland, A.1    Glover, E.2
  • 34
    • 0033969839 scopus 로고    scopus 로고
    • Activation of transcription factors activator protein-1 and nuclear factor-κB by 2,3,7,8-tetrachlorodibenzo-p-dioxin
    • Puga A., Barnes S.J., Chang C., Zhu H., Nephew K.P., Khan S.A., and Shertzer H.G. Activation of transcription factors activator protein-1 and nuclear factor-κB by 2,3,7,8-tetrachlorodibenzo-p-dioxin. Biochem. Pharmacol. 59 (2000) 997-1005
    • (2000) Biochem. Pharmacol. , vol.59 , pp. 997-1005
    • Puga, A.1    Barnes, S.J.2    Chang, C.3    Zhu, H.4    Nephew, K.P.5    Khan, S.A.6    Shertzer, H.G.7
  • 35
    • 0023794239 scopus 로고
    • The reaction mechanism of bovine kidney biliverdin reductase
    • Rigney E., and Mantle T.J. The reaction mechanism of bovine kidney biliverdin reductase. Biochim. Biophys. Acta 957 (1988) 237-242
    • (1988) Biochim. Biophys. Acta , vol.957 , pp. 237-242
    • Rigney, E.1    Mantle, T.J.2
  • 36
    • 0024603231 scopus 로고
    • The kinetics of ox kidney biliverdin reductase in the pre-steady state. Evidence that the dissociation of bilirubin is the rate-determining step
    • Rigney E., Mantle T.J., and Dickinson F.M. The kinetics of ox kidney biliverdin reductase in the pre-steady state. Evidence that the dissociation of bilirubin is the rate-determining step. Biochem. J. 259 (1989) 709-713
    • (1989) Biochem. J. , vol.259 , pp. 709-713
    • Rigney, E.1    Mantle, T.J.2    Dickinson, F.M.3
  • 37
    • 0036670448 scopus 로고    scopus 로고
    • Heme oxygenase-1: molecular mechanisms of gene expression in oxygen-related stress
    • Ryter S.W., and Choi A.M. Heme oxygenase-1: molecular mechanisms of gene expression in oxygen-related stress. Antioxid. Redox. Signal. 4 (2002) 625-632
    • (2002) Antioxid. Redox. Signal. , vol.4 , pp. 625-632
    • Ryter, S.W.1    Choi, A.M.2
  • 39
    • 0242525192 scopus 로고    scopus 로고
    • The heme oxygenase dilemma in cellular homeostasis: new insights for the feedback regulation of heme catabolism
    • Shibahara S. The heme oxygenase dilemma in cellular homeostasis: new insights for the feedback regulation of heme catabolism. Tohoku J. Exp. Med. 200 (2003) 167-186
    • (2003) Tohoku J. Exp. Med. , vol.200 , pp. 167-186
    • Shibahara, S.1
  • 40
    • 0037095038 scopus 로고    scopus 로고
    • Structure-activity relationships and dose responses of polychlorinated dibenzo-p-dioxins for short-term effects in 2,3,7,8-tetrachlorodibenzo-p-dioxin-resistant and -sensitive rat strains
    • Simanainen U., Tuomisto J.T., Tuomisto J., and Viluksela M. Structure-activity relationships and dose responses of polychlorinated dibenzo-p-dioxins for short-term effects in 2,3,7,8-tetrachlorodibenzo-p-dioxin-resistant and -sensitive rat strains. Toxicol. Appl. Pharmacol. 181 (2002) 38-47
    • (2002) Toxicol. Appl. Pharmacol. , vol.181 , pp. 38-47
    • Simanainen, U.1    Tuomisto, J.T.2    Tuomisto, J.3    Viluksela, M.4
  • 42
    • 0025042326 scopus 로고
    • Oxidative stress induced by 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD)
    • Stohs S.J. Oxidative stress induced by 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD). Free Radic. Biol. Med. 9 (1990) 79-90
    • (1990) Free Radic. Biol. Med. , vol.9 , pp. 79-90
    • Stohs, S.J.1
  • 44
    • 0034662427 scopus 로고    scopus 로고
    • Tissue-specific gene expression of heme oxygenase-1 (HO-1) and non-specific δ-aminolevulinate synthase (ALAS-N) in a rat model of septic multiple organ dysfunction syndrome
    • Suzuki T., Takahashi T., Yamasaki A., Fujiwara T., Hirakawa M., and Akagi R. Tissue-specific gene expression of heme oxygenase-1 (HO-1) and non-specific δ-aminolevulinate synthase (ALAS-N) in a rat model of septic multiple organ dysfunction syndrome. Biochem. Pharmacol. 60 (2000) 275-283
    • (2000) Biochem. Pharmacol. , vol.60 , pp. 275-283
    • Suzuki, T.1    Takahashi, T.2    Yamasaki, A.3    Fujiwara, T.4    Hirakawa, M.5    Akagi, R.6
  • 45
    • 0033062111 scopus 로고    scopus 로고
    • The AH receptor and a novel gene determine acute toxic responses to TCDD: segregation of the resistant alleles to different rat lines
    • Tuomisto J.T., Viluksela M., Pohjanvirta R., and Tuomisto J. The AH receptor and a novel gene determine acute toxic responses to TCDD: segregation of the resistant alleles to different rat lines. Toxicol. Appl. Pharmacol. 155 (1999) 71-81
    • (1999) Toxicol. Appl. Pharmacol. , vol.155 , pp. 71-81
    • Tuomisto, J.T.1    Viluksela, M.2    Pohjanvirta, R.3    Tuomisto, J.4
  • 46
    • 0028080445 scopus 로고
    • Dose response and time course of alterations in tryptophan metabolism by 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in the most TCDD-susceptible and the most TCDD-resistant rat strain: relationship with TCDD lethality
    • Unkila M., Pohjanvirta R., MacDonald E., Tuomisto J.T., and Tuomisto J. Dose response and time course of alterations in tryptophan metabolism by 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in the most TCDD-susceptible and the most TCDD-resistant rat strain: relationship with TCDD lethality. Toxicol. Appl. Pharmacol. 128 (1994) 280-292
    • (1994) Toxicol. Appl. Pharmacol. , vol.128 , pp. 280-292
    • Unkila, M.1    Pohjanvirta, R.2    MacDonald, E.3    Tuomisto, J.T.4    Tuomisto, J.5
  • 47
    • 0023775434 scopus 로고
    • Structure, turnover, and heme-mediated suppression of the level of mRNA encoding rat liver δ-aminolevulinate synthase
    • Yamamoto M., Kure S., Engel J.D., and Hiraga K. Structure, turnover, and heme-mediated suppression of the level of mRNA encoding rat liver δ-aminolevulinate synthase. J. Biol. Chem. 263 (1988) 15973-15979
    • (1988) J. Biol. Chem. , vol.263 , pp. 15973-15979
    • Yamamoto, M.1    Kure, S.2    Engel, J.D.3    Hiraga, K.4
  • 48
    • 0020670623 scopus 로고
    • Effects of halogenated dibenzo-p-dioxins on plasma disappearance and biliary excretion of ouabain in rats
    • Yang K.H., Yoo B.S., and Choe S.Y. Effects of halogenated dibenzo-p-dioxins on plasma disappearance and biliary excretion of ouabain in rats. Toxicol. Lett. 15 (1983) 259-264
    • (1983) Toxicol. Lett. , vol.15 , pp. 259-264
    • Yang, K.H.1    Yoo, B.S.2    Choe, S.Y.3
  • 49
    • 0015698089 scopus 로고
    • Hematologic and clinical chemistry effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin in laboratory animals
    • Zinkl J.G., Vos J.G., Moore J.A., and Gupta B.N. Hematologic and clinical chemistry effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin in laboratory animals. Environ. Health Perspect. 5 (1973) 111-118
    • (1973) Environ. Health Perspect. , vol.5 , pp. 111-118
    • Zinkl, J.G.1    Vos, J.G.2    Moore, J.A.3    Gupta, B.N.4


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