메뉴 건너뛰기




Volumn 23, Issue 9, 2008, Pages 1448-1458

RASSF1A expression inhibits the growth of hepatocellular carcinoma from Qidong County

Author keywords

Apoptosis; Cyclin D1; Hepatocarcinogenesis; Mitomycin; Tumor suppressor

Indexed keywords

CYCLIN D1; HEPATITIS B SURFACE ANTIGEN; MITOMYCIN; RAS ASSOCIATION DOMAIN FAMILY PROTEIN 1A;

EID: 49849099834     PISSN: 08159319     EISSN: 14401746     Source Type: Journal    
DOI: 10.1111/j.1440-1746.2007.05067.x     Document Type: Article
Times cited : (16)

References (39)
  • 1
    • 84911460272 scopus 로고    scopus 로고
    • Epidemic tendency analysis of hepatocellular carcinoma in Qidong County from 1969 to 2003
    • Chen JG, Yao HY, Zhu J, Zhang YH. Epidemic tendency analysis of hepatocellular carcinoma in Qidong County from 1969 to 2003. Chin. Med. Res. 2002 2 : 684 6.
    • (2002) Chin. Med. Res. , vol.2 , pp. 684-686
    • Chen, J.G.1    Yao, H.Y.2    Zhu, J.3    Zhang, Y.H.4
  • 2
    • 0033541491 scopus 로고    scopus 로고
    • Hepatocellular carcinoma
    • Schafer DF, Sorrell MF. Hepatocellular carcinoma. Lancet 1999 353 : 1253 7.
    • (1999) Lancet , vol.353 , pp. 1253-1257
    • Schafer, D.F.1    Sorrell, M.F.2
  • 3
    • 0031014484 scopus 로고    scopus 로고
    • Treatment of hepatocellular carcinoma
    • Bruix J. Treatment of hepatocellular carcinoma. Hepatology 1997 25 : 259 62.
    • (1997) Hepatology , vol.25 , pp. 259-262
    • Bruix, J.1
  • 4
    • 0345299824 scopus 로고    scopus 로고
    • Liver Transplantation for the treatment of small hepatocellular carcinomas in patients with cirrhosis
    • Mazzaferro V, Regalia E, Doci R et al. Liver Transplantation for the treatment of small hepatocellular carcinomas in patients with cirrhosis. N. Engl. J. Med. 1996 334 : 693 700.
    • (1996) N. Engl. J. Med. , vol.334 , pp. 693-700
    • Mazzaferro, V.1    Regalia, E.2    Doci, R.3
  • 5
    • 0030842686 scopus 로고    scopus 로고
    • Treatment of hepatocellular carcinoma in patients with cirrhosis
    • Trinchet JC, Beaugrand M. Treatment of hepatocellular carcinoma in patients with cirrhosis. J. Hepatol. 1997 27 : 756 65.
    • (1997) J. Hepatol. , vol.27 , pp. 756-765
    • Trinchet, J.C.1    Beaugrand, M.2
  • 6
    • 0023145547 scopus 로고
    • The molecular genetics of cancer
    • Bishop JM. The molecular genetics of cancer. Science 1987 235 : 305 11.
    • (1987) Science , vol.235 , pp. 305-311
    • Bishop, J.M.1
  • 7
    • 0025169651 scopus 로고
    • Analysis of ras gene mutations in human hepatic malignant tumors by polymerase chain reaction and direct sequencing
    • Tada M, Omata M, Ohto M. Analysis of ras gene mutations in human hepatic malignant tumors by polymerase chain reaction and direct sequencing. Cancer Res. 1990 50 : 1121 4.
    • (1990) Cancer Res. , vol.50 , pp. 1121-1124
    • Tada, M.1    Omata, M.2    Ohto, M.3
  • 8
    • 0036699940 scopus 로고    scopus 로고
    • Molecular pathogenesis of human hepatocellular carcinoma
    • Thorgeirsson SS, Grisham JW. Molecular pathogenesis of human hepatocellular carcinoma. Nat. Genet. 2002 31 : 339 46.
    • (2002) Nat. Genet. , vol.31 , pp. 339-346
    • Thorgeirsson, S.S.1    Grisham, J.W.2
  • 9
    • 0033918563 scopus 로고    scopus 로고
    • Epigenetic inactivation of a RAS association domain family protein from the lung tumor suppressor locus 3p21.3
    • Dammann R, Li C, Yoon JH, Chin PL, Bates S, Pfeifer GP. Epigenetic inactivation of a RAS association domain family protein from the lung tumor suppressor locus 3p21.3. Nat. Genet. 2000 25 : 315 19.
    • (2000) Nat. Genet. , vol.25 , pp. 315-319
    • Dammann, R.1    Li, C.2    Yoon, J.H.3    Chin, P.L.4    Bates, S.5    Pfeifer, G.P.6
  • 10
    • 0037096818 scopus 로고    scopus 로고
    • The RASSF1A tumor suppressor gene is inactivated in prostate tumors and suppresses growth of prostate carcinoma cells
    • Kuzmin I, Gillespie JW, Protopopov A et al. The RASSF1A tumor suppressor gene is inactivated in prostate tumors and suppresses growth of prostate carcinoma cells. Cancer Res. 2002 62 : 3498 502.
    • (2002) Cancer Res. , vol.62 , pp. 3498-3502
    • Kuzmin, I.1    Gillespie, J.W.2    Protopopov, A.3
  • 11
    • 0035912820 scopus 로고    scopus 로고
    • The candidate tumor suppressor gene, RASSF1A, from human chromosome 3p21.3 is involved in kidney tumorigenesis
    • Dreijerink K, Braga E, Kuzmin I et al. The candidate tumor suppressor gene, RASSF1A, from human chromosome 3p21.3 is involved in kidney tumorigenesis. Proc. Natl. Acad. Sci. USA 2001 98 : 7504 9.
    • (2001) Proc. Natl. Acad. Sci. USA , vol.98 , pp. 7504-7509
    • Dreijerink, K.1    Braga, E.2    Kuzmin, I.3
  • 12
    • 0035476236 scopus 로고    scopus 로고
    • Frequent epigenetic inactivation of RASSF1A by aberrant promoter hypermethylation in human gastric adenocarcinoma
    • Byun DS, Lee MG, Chae KS, Ryu BG, Chi SG. Frequent epigenetic inactivation of RASSF1A by aberrant promoter hypermethylation in human gastric adenocarcinoma. Cancer Res. 2001 61 : 7034 8.
    • (2001) Cancer Res. , vol.61 , pp. 7034-7038
    • Byun, D.S.1    Lee, M.G.2    Chae, K.S.3    Ryu, B.G.4    Chi, S.G.5
  • 13
    • 0035884193 scopus 로고    scopus 로고
    • Frequent epigenetic inactivation of RASSF1A in human bladder carcinoma
    • Lee MG, Kim HY, Byun DS et al. Frequent epigenetic inactivation of RASSF1A in human bladder carcinoma. Cancer Res. 2001 61 : 6688 92.
    • (2001) Cancer Res. , vol.61 , pp. 6688-6692
    • Lee, M.G.1    Kim, H.Y.2    Byun, D.S.3
  • 14
    • 0036845755 scopus 로고    scopus 로고
    • Frequent loss of chromosome 3p and hypermethylation of RASSF1A in cholangiocarcinoma
    • Wong N, Li L, Tsang K, Lai PB, To KF, Johnson PJ. Frequent loss of chromosome 3p and hypermethylation of RASSF1A in cholangiocarcinoma. J. Hepatol. 2002 37 : 633 9.
    • (2002) J. Hepatol. , vol.37 , pp. 633-639
    • Wong, N.1    Li, L.2    Tsang, K.3    Lai, P.B.4    To, K.F.5    Johnson, P.J.6
  • 15
    • 0036264815 scopus 로고    scopus 로고
    • The RASSF1A tumor suppressor blocks cell cycle progression and inhibits cyclin D1 accumulation
    • Shivakumar L, Minna J, Sakamaki T, Pestell R, White MA. The RASSF1A tumor suppressor blocks cell cycle progression and inhibits cyclin D1 accumulation. Mol. Cell. Biol. 2002 22 : 4309 18.
    • (2002) Mol. Cell. Biol. , vol.22 , pp. 4309-4318
    • Shivakumar, L.1    Minna, J.2    Sakamaki, T.3    Pestell, R.4    White, M.A.5
  • 16
    • 85047696339 scopus 로고    scopus 로고
    • The putative tumor suppressor RASSF1A homodimerizes and heterodimerizes with the Ras-GTP binding protein Nore1
    • Ortiz-Vega S, Khokhlatchev A, Nedwidek M et al. The putative tumor suppressor RASSF1A homodimerizes and heterodimerizes with the Ras-GTP binding protein Nore1. Oncogene 2002 21 : 1381 90.
    • (2002) Oncogene , vol.21 , pp. 1381-1390
    • Ortiz-Vega, S.1    Khokhlatchev, A.2    Nedwidek, M.3
  • 17
    • 0033773041 scopus 로고    scopus 로고
    • Down-regulation of cyclin D1 expression by prostaglandin A2 is mediated by enhanced cyclin D1 mRNA turnover
    • Lin S, Wang W, Wilson GM et al. Down-regulation of cyclin D1 expression by prostaglandin A2 is mediated by enhanced cyclin D1 mRNA turnover. Mol. Cell. Biol. 2000 20 : 7903 13.
    • (2000) Mol. Cell. Biol. , vol.20 , pp. 7903-7913
    • Lin, S.1    Wang, W.2    Wilson, G.M.3
  • 18
    • 0041695472 scopus 로고    scopus 로고
    • Intensive hypermethylation of the CpG island of Ras association domain family 1A in Hepatitis B Virus-associated hepatocellular carcinomas
    • Zhong S, Yeo W, Tang MW et al. Intensive hypermethylation of the CpG island of Ras association domain family 1A in Hepatitis B Virus-associated hepatocellular carcinomas. Clin. Cancer Res. 2003 9 : 3376 82.
    • (2003) Clin. Cancer Res. , vol.9 , pp. 3376-3382
    • Zhong, S.1    Yeo, W.2    Tang, M.W.3
  • 19
    • 0037468934 scopus 로고    scopus 로고
    • Frequent epigenetic inactivation of the RASSF1A gene in hepatocellular carcinoma
    • Schagdarsurengin U, Wilkens L, Steinemann D et al. Frequent epigenetic inactivation of the RASSF1A gene in hepatocellular carcinoma. Oncogene 2003 22 : 1866 71.
    • (2003) Oncogene , vol.22 , pp. 1866-1871
    • Schagdarsurengin, U.1    Wilkens, L.2    Steinemann, D.3
  • 20
    • 0031442751 scopus 로고    scopus 로고
    • Increased DNA methyltransferase expression is associated with an early stage of human hepatocarcinogenesis
    • Sun L, Hui AM, Kanai Y, Sakamoto M, Hirohashi S. Increased DNA methyltransferase expression is associated with an early stage of human hepatocarcinogenesis. Jpn. J. Cancer Res. 1997 88 : 1165 70.
    • (1997) Jpn. J. Cancer Res. , vol.88 , pp. 1165-1170
    • Sun, L.1    Hui, A.M.2    Kanai, Y.3    Sakamoto, M.4    Hirohashi, S.5
  • 21
    • 0037094189 scopus 로고    scopus 로고
    • DNA methylation and environmental exposures in human hepatocellular carcinoma
    • Shen LL, Ahuja N, Shen Y et al. DNA methylation and environmental exposures in human hepatocellular carcinoma. Cancer Inst. 2002 94 : 755 61.
    • (2002) Cancer Inst. , vol.94 , pp. 755-761
    • Shen, L.L.1    Ahuja, N.2    Shen, Y.3
  • 22
    • 0028965135 scopus 로고
    • Cellular interactions and metabolism of aflatoxin: An update
    • McLean M, Dutton MF. Cellular interactions and metabolism of aflatoxin: an update. Pharmacol. Ther. 1995 65 : 163 92.
    • (1995) Pharmacol. Ther. , vol.65 , pp. 163-192
    • McLean, M.1    Dutton, M.F.2
  • 23
    • 0028071555 scopus 로고
    • Mutations in the p53 tumor suppressor gene: Clues to cancer etiology and molecular pathogenesis
    • Greenblatt MS, Bennett WP, Hollstein M, Harris CC. Mutations in the p53 tumor suppressor gene: clues to cancer etiology and molecular pathogenesis. Cancer Res. 1994 54 : 4855 78.
    • (1994) Cancer Res. , vol.54 , pp. 4855-4878
    • Greenblatt, M.S.1    Bennett, W.P.2    Hollstein, M.3    Harris, C.C.4
  • 24
  • 25
    • 0036789450 scopus 로고    scopus 로고
    • High frequency of promoter hypermethylation of RASSF1A and p16 and its relationship to aflatoxin B1-DNA adduct levels in human hepatocellular carcinoma
    • Zhang YJ, Ahsan H, Chen Y et al. High frequency of promoter hypermethylation of RASSF1A and p16 and its relationship to aflatoxin B1-DNA adduct levels in human hepatocellular carcinoma. Mol. Carcinog. 2002 35 : 85 92.
    • (2002) Mol. Carcinog. , vol.35 , pp. 85-92
    • Zhang, Y.J.1    Ahsan, H.2    Chen, Y.3
  • 26
    • 0028984962 scopus 로고
    • Aflatoxin B-induced 8-hydroxydeoxyguanosine formations in rat hepatic DNA
    • Shen HM, Ong CN, Lee BL, Shi CY. Aflatoxin B-induced 8- hydroxydeoxyguanosine formations in rat hepatic DNA. Carcinogenesis 1995 16 : 419 22.
    • (1995) Carcinogenesis , vol.16 , pp. 419-422
    • Shen, H.M.1    Ong, C.N.2    Lee, B.L.3    Shi, C.Y.4
  • 27
    • 24344435500 scopus 로고    scopus 로고
    • The RASSF1A isoform of RASSF1 promotes microtubule stability and suppresses tumorigenesis
    • Weyden L, Tachiban KK, Gonzalez MA et al. The RASSF1A isoform of RASSF1 promotes microtubule stability and suppresses tumorigenesis. Mol. Cell. Biol. 2005 25 : 8356 67.
    • (2005) Mol. Cell. Biol. , vol.25 , pp. 8356-8367
    • Weyden, L.1    Tachiban, K.K.2    Gonzalez, M.A.3
  • 29
    • 0035377410 scopus 로고    scopus 로고
    • Genetic and epigenetic events in human hepatocarcinogenesis
    • Kondoh N, Wakatsuki T, Hada A et al. Genetic and epigenetic events in human hepatocarcinogenesis. Int. J. Oncol. 2001 18 : 1271 8.
    • (2001) Int. J. Oncol. , vol.18 , pp. 1271-1278
    • Kondoh, N.1    Wakatsuki, T.2    Hada, A.3
  • 30
    • 0027154638 scopus 로고
    • Cyclin D1 is a nuclear protein required for cell cycle progression in G1
    • Baldin V, Lukas J, Marcote MJ, Pagano M, Draetta G. Cyclin D1 is a nuclear protein required for cell cycle progression in G1. Genes Dev. 1993 7 : 812 21.
    • (1993) Genes Dev. , vol.7 , pp. 812-821
    • Baldin, V.1    Lukas, J.2    Marcote, M.J.3    Pagano, M.4    Draetta, G.5
  • 31
    • 0028261383 scopus 로고
    • Cyclin D1 expression is regulated by the retinoblastoma protein
    • Muller H, Lukas J, Schneider A et al. Cyclin D1 expression is regulated by the retinoblastoma protein. Proc. Natl. Acad. Sci. USA 1994 91 : 2945 9.
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 2945-2949
    • Muller, H.1    Lukas, J.2    Schneider, A.3
  • 32
    • 0030916209 scopus 로고    scopus 로고
    • Inhibition of cyclin D1 phosphorylation on threonine-286 prevents its rapid degradation via the ubiquitin-proteasome pathway
    • Diehl JA, Zindy F, Sherr CJ. Inhibition of cyclin D1 phosphorylation on threonine-286 prevents its rapid degradation via the ubiquitin-proteasome pathway. Genes Dev. 1997 11 : 957 72.
    • (1997) Genes Dev. , vol.11 , pp. 957-972
    • Diehl, J.A.1    Zindy, F.2    Sherr, C.J.3
  • 33
    • 0033839158 scopus 로고    scopus 로고
    • Stabilization of cyclin D1 mRNA via the phosphatidylinositol 3-kinase pathway in MCF-7 human breast cancer cells
    • Dufourny B, van Teeffelen HA, Hamelers IH, Sussenbach JS, Steenbergh PH. Stabilization of cyclin D1 mRNA via the phosphatidylinositol 3-kinase pathway in MCF-7 human breast cancer cells. J. Endocrinol. 2000 166 : 329 38.
    • (2000) J. Endocrinol. , vol.166 , pp. 329-338
    • Dufourny, B.1    Van Teeffelen, H.A.2    Hamelers, I.H.3    Sussenbach, J.S.4    Steenbergh, P.H.5
  • 34
    • 0034680870 scopus 로고    scopus 로고
    • Ras uses the novel tumor suppressor RASSF1 as an effector to mediate apoptosis
    • Vos MD, Ellis CA, Bell A, Birrer MJ, Clark GJ. Ras uses the novel tumor suppressor RASSF1 as an effector to mediate apoptosis. J. Biol. Chem. 2000 275 : 35669 72.
    • (2000) J. Biol. Chem. , vol.275 , pp. 35669-35672
    • Vos, M.D.1    Ellis, C.A.2    Bell, A.3    Birrer, M.J.4    Clark, G.J.5
  • 35
    • 0032701521 scopus 로고    scopus 로고
    • Disruption of p53 in human cancer cells alters the responses to therapeutic agents
    • Bunz F, Hwang PM, Torrance C et al. Disruption of p53 in human cancer cells alters the responses to therapeutic agents. J. Clin. Invest. 1999 104 : 263 9.
    • (1999) J. Clin. Invest. , vol.104 , pp. 263-269
    • Bunz, F.1    Hwang, P.M.2    Torrance, C.3
  • 36
    • 0041328595 scopus 로고    scopus 로고
    • P14ARF upregulation of p53 and enhanced effects of 5-fluorouracil in pancreatic cancer
    • Zhang Q, Ni Q, Gan J et al. p14ARF upregulation of p53 and enhanced effects of 5-fluorouracil in pancreatic cancer. Chin. Med. J. (Engl.). 2003 116 : 1150 5.
    • (2003) Chin. Med. J. (Engl.). , vol.116 , pp. 1150-1155
    • Zhang, Q.1    Ni, Q.2    Gan, J.3
  • 37
    • 0030610390 scopus 로고    scopus 로고
    • waf1 leads to increased inhibition of E2F-1 phosphorylation and sensitivity to anticancer drugs in retinoblastoma-negative human sarcoma cells
    • waf1 leads to increased inhibition of E2F-1 phosphorylation and sensitivity to anticancer drugs in retinoblastoma-negative human sarcoma cells. Cancer Res. 1997 57 : 2193 9.
    • (1997) Cancer Res. , vol.57 , pp. 2193-2199
    • Li, W.W.1    Fan, J.2    Hochhauser, D.3    Bertino, J.R.4
  • 38
    • 0033400809 scopus 로고    scopus 로고
    • Apoptosis and cancer drug targeting
    • Sellers WR, Fisher DE. Apoptosis and cancer drug targeting. J. Clin. Invest. 1999 104 : 1655 61.
    • (1999) J. Clin. Invest. , vol.104 , pp. 1655-1661
    • Sellers, W.R.1    Fisher, D.E.2
  • 39
    • 3142710380 scopus 로고    scopus 로고
    • The scaffold protein CNK1 interacts with the tumor suppressor RASSF1A and augments RASSF1A-induced cell death
    • Rabizadeh S, Xavier RJ, Ishiguro K et al. The scaffold protein CNK1 interacts with the tumor suppressor RASSF1A and augments RASSF1A-induced cell death. J. Biol. Chem. 2004 279 : 29247 54.
    • (2004) J. Biol. Chem. , vol.279 , pp. 29247-29254
    • Rabizadeh, S.1    Xavier, R.J.2    Ishiguro, K.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.