A high concentration of resiniferatoxin inhibits ion channel function in clonal neuroendocrine cells

Anesthesia and Analgesia

Volumn 107, Issue 1, 2008, Pages 318-324

  Sugimoto, Kenji ^a   Kissin, Igor ^a   Strichartz, Gary ^a  

^a BRIGHAM AND WOMEN S HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM CHANNEL L TYPE; CALCIUM ION; POTASSIUM CHLORIDE; POTASSIUM ION; RESINIFERATOXIN; SODIUM ION; VANILLOID RECEPTOR 1; VERATRIDINE; VOLTAGE GATED CALCIUM CHANNEL; VOLTAGE GATED SODIUM CHANNEL; CALCIUM; CALCIUM CHANNEL; CALCIUM CHANNEL BLOCKING AGENT; CAPSAICIN; DITERPENE; PROTEIN KINASE C; SODIUM; SODIUM CHANNEL BLOCKING AGENT; TRPV1 PROTEIN, RAT; VANILLOID RECEPTOR;

ANALGESIA; ANIMAL CELL; ANTINOCICEPTION; ARTICLE; CALCIUM TRANSPORT; CELL CULTURE; CHANNEL GATING; CONTROLLED STUDY; FLUORESCENCE; LIPID BILAYER; LONG TERM EXPOSURE; NERVE CELL MEMBRANE STEADY POTENTIAL; NEUROSECRETORY CELL; NONHUMAN; PRIORITY JOURNAL; RAT; SODIUM TRANSPORT; ANIMAL; CYTOLOGY; DRUG EFFECT; METABOLISM; NEUROSECRETION; PHYSIOLOGY;

ANIMALS; CALCIUM; CALCIUM CHANNEL BLOCKERS; CALCIUM CHANNELS; CAPSAICIN; CELLS, CULTURED; DITERPENES; NEUROSECRETORY SYSTEMS; PROTEIN KINASE C; RATS; SODIUM; SODIUM CHANNEL BLOCKERS; TRPV CATION CHANNELS; VERATRIDINE;

EID: 49849087520     PISSN: 00032999     EISSN: None     Source Type: Journal    
DOI: 10.1213/ane.0b013e31816d140a     Document Type: Article

References (25)

1. Caterina MJ, Schumacher MA, Tominaga M, Rosen TA, Levine JD, Julius D. The capsaicin receptor: a heat-activated ion channel in the pain pathway. Nature 1997;389:816-24
2. Szallasi A, Blumberg PM. Vanilloid (Capsaicin) receptors and mechanisms. Pharmacol Rev 1999;51:159-212
3. Karai L, Brown DC, Mannes AJ, Connelly ST, Brown J, Gandal M, Wellisch OM, Neubert JK, Olah Z, Iadarola MJ. Deletion of vanilloid receptor 1-expressing primary afferent neurons for pain control. J Clin Invest 2004;113:1344-52
4. Brown DC, Iadarola MJ, Perkowski SZ. Physiologic and antinociceptive effects of intrathecal resiniferatoxin in a canine bone cancer model. Anesthesiology 2005;103:1052-9
5. Kissin I, Bright CA, Bradley EL Jr. Selective and long-lasting neural blockade with resiniferatoxin prevents inflammatory pain hypersensitivity. Anesth Analg 2002;94:1253-8
6. Kissin I, Freitas CF, Bradley EL Jr. Perineural resiniferatoxin prevents the development of hyperalgesia produced by loose ligation of the sciatic nerve in rats. Anesth Analg 2007; 104:1210-6
7. Lundbaek JA, Birn P, Tape SE, Toombes, GE, Sogaard R, Koeppe RE II, Gruner SM, Hansen AJ, Andersen OS. Capsaicin regulates voltage-dependent sodium channels by altering lipid bilayer elasticity. Mol Pharmacol 2005;68:680-9
8. + channel. Pain 2007;127:73-83
9. + channels. Basic Clin Pharmacol Toxicol 2007;100:91-5
10. Fessenden JD, Perez CF, Goth S, Pessah IN, Allen, PD. Identification of a key determinant of ryanodine receptor type 1 required for activation by 4-chloro-m-cresol. J Biol Chem 2003;278:28727-35
11. Ulbricht W. The effect of veratridine on excitable membranes of nerve and muscle. Ergeb Physiol 1969;61:18-71
12. Strichartz G, Rando T, Wang GK. An integrated view of the molecular toxinology of sodium channel gating in excitable cells. Annu Rev Neurosci 1987;10:237-67
13. Dubinsky JM, Oxford GS. Ionic currents in two strains of rat anterior pituitary tumor cells. J Gen Physiol 1984;83:309-39
14. + channels and its effect on closing rate. Proc Natl Acad Sci USA 1999;96:4154-7
15. Xiong Z, Strichartz GR. Inhibitionby local anesthetics of calcium channels in rat anterior pituitary cells. Eur J Pharm 1998; 363:81-90
16. Kissin I, Freitas CF, Mulhern HI, DeGirolami U. Sciatic nerve block with resinifreatoxin: an electron microscopic study of unmyelinated fibers in the rat. Anesth Analg 2007;105:825-31
17. Raisinghani M, Pabbidi RM, Premkumar LS. Activation of transient receptor potential vanilloid 1 (TRPV1) by resinifera-toxin. J Physiol 2005;567:771-86
18. Olah Z, Szabo T, Karai L, Hough C, Fields RD, Caudle RM, Blumberg PM, Iadarola MJ. Ligand-induced dynamic membrane changes and cell deletion conferred by vanilloid receptor 1. J Biol Chem 2001;276:11021-30
19. Cao Xueh Cao Xues Xie H, Yang R, Lei G, Li F, Li A, Liu C, Liu L. Effects of capsaicin on VGSCs in TRPV1 - / - mice. Brain Res 2007;1163:33-43
20. Guo X, Castle NA, Chernoff DM, Strichartz GR. Comparative inhibition of voltage gated cation channels by anesthetics. Ann NY Acad Sci 1991;625:181-99
21. Sherman SJ, Catterall WA. Electrical activity and cytosolic calcium regulate levels of tetrodotoxin-sensitive sodium channels in cultured rat muscle cells. Proc Natl Acad Sci USA 1984;81:262-6
22. Wada A, Yanagita T, Yokoo H, Kobayashi H. Regulation of cell surface expression of voltage-dependent Nav1.7 sodium channels: mRNA stability and post-transcriptional control in adrenal chromaffin cells. Front Biosci 2004;9:1954-66
23. Monjaraz E, Navarrete A, Lopez-Santiago LF, Vega AV, Arias-Montano, JA, Cota, G. L-type calcium channel activity regulates sodium channel levels in rat pituitary GH3 cells. J Physiol 2000;523(Pt 1):45-55
24. Driedger PE, Blumberg PM. Different biological targets for resiniferatoxin and phorbol 12-myrsitate 13-acetate. Cancer Res 1980;40:1400-4
25. Harvey JS, Davis C, James IF, Burgess GM. Activation of protein kinase C by the capsaicin analogue resiniferatoxin in sensory neurones. J Neurochem 1995;65:1309-17