Effect of ethanol extract of safflower seed on bone loss in ovariectomized rat

Food Science and Biotechnology

Volumn 16, Issue 3, 2007, Pages 392-397

  Cho, Sung Hee ^b   Choi, Sang Won ^b   Choi, Young Sun ^c   Kim, Hee Jung ^a   Park, Youn Hee ^a   Bae, Yong Chul ^d   Lee, Won Jung ^a  

^a Kyungpook National University School of Medicine   (South Korea)

^b Catholic University of Daegu   (South Korea)

^c Daegu University   (South Korea)

^d Kyungpook National University   (South Korea)

Author keywords

Bone loss; Osteoblast; Phenolic compound; Safflower (Carthamus tinctorius L.) seed extract

Indexed keywords

CARTHAMUS TINCTORIUS; RATTUS;

EID: 49749135567     PISSN: 12267708     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (49)

1. st ed. Parthenon Publishing, Lancashire, UK. pp. 17-30 (2003)
2. Michaelsson K, Baron JA, Farahmand BY, Johnell O, Magnesson C, Persson PQ Persson I, Ljunghall S. Hormone replacement therapy and risk of hip fracture: population based case-control study. The Swedish hip fracture study group. Brit. Med. J. 316: 1858-1863 (1998)
3. Writing Group for the Women's Health Initiative Investigators. Risks and benefits of estrogen plus progestin in healthy postmenopausal women: principal results from the Women's Health Initiative randomized controlled trial. J. Am. Med. Assoc. 288: 321-333 (2002)
4. Cahnson P. Historical perspective of hormone replacement therapy. Rev. Pratician 55: 369-375 (2005)
5. Morello KC, Wurz GT, DeGregorio MW. SERMs: Current status and future trends. Crit. Rev. Oncol. Hemat. 43: 63-76 (2002)
6. Labrie F. Future perspectives of selective estrogen receptor modulators used alone and in combination with DHEA. Endocr. - Relat. Cancer 13: 335-355 (2006)
7. Vogelvang TE, van der Mooren MJ, Mijatovic V. Hormone replacement therapy, selective estrogen receptor modulators, and tissue-specific compounds: cardiovascular effects and clinical implications. Treat Endocrinol. 3: 105-115 (2004)
8. Bolego C, Vegeto E, Pinna C, Maggi A, Cignarella A. Selective agonists of estrogen receptor isoforms: new perspectives for cardiovascular disease. Arterioscl. Thromb. Vas. 26: 2192-2199 (2006)
9. Francucci CM, Romagni P, Boscaro M. Raloxifene: bone and cardiovascular effects. J. Endocrinol. Invest. 28: 85-89 (2005)
10. Cornwell T, Cohick W, Raskin I. Dietary phytoestrogens and health. Phytochemistry 65: 995-1016 (2004)
11. Tham DM, Gardner CD, Haskell WL. Clinical review 97: Potential health benefits of dietary phytoestrogens: a review of the clinical, epidemiological, and mechanistic evidence. Eur. J. Clin. Nutr. 52: 850-855 (1998)
12. Adlercreut H, Mazur W, Stumpf K, Kilkkinen A, Pietinen P, Hulten K, Hallmans G. Food containing phytoestrogens, and breast cancer. Biofactors 12: 89-93 (2000)
13. Knight DC, Eden JA. A review of the clinical effects of phytoestrogens. Obstet. Gynecol. 87: 897-904 (1996)
14. Draper CR, Edel MJ, Dick LM, Randall AG, Martin GB, Prince RL. Phytoestrogens reduce bone loss and bone resorption in oophorectomized rats. J. Nutr. 127: 1795-1799 (1997)
15. Anderson JB, Garner SC. The effects of phytoestrogens on bone. Nutr. Res. 17: 1617-1632 (1997)
16. Arjmandi BH, Alekel L, Hollis BW, Amin D, Stacewicz-Sapuntzakis M, Guo P, Kukreja SC. Dietary soybean protein prevents bone loss in an ovariectomized rat model of osteoporosis. J. Nutr. 126: 161-167 (1996)
17. Arjmandi BH, Birnbaum R, Goyal NV, Getlinger MJ, Juma S, Alekel L, Hasler CM, Drum ML, Hollis BW, Kukreja SC. Bone-sparing effect of soy protein in ovarian hormone-deficient rats is related to its isoflavone content. Am. J. Clin. Nutr. 68:1364S-1368S (1998)
18. Alekel L, Germain AS, Peterson CT, Hanson KB, Stewart JW, Toda T. Isoflavone-rich soy protein isolate attenuates bone loss in the lumbar spine of perimenopausal women. Am. J. Clin. Nutr. 72: 844-852 (2000)
19. Potter SM, Baum JA, Teng H, Stillman RJ, Shay NF, Erdman JW. Soy protein and isoflavones: their effects on blood lipids and bone density in postmenopausal women. Am. J. Clin. Nutr. 68: 1375S-1379S (1998)
20. Huang HY, Yang HP, Yang HT, Yang TC, Shieh MJ, Huang SY. One-year soy isoflavone supplementation prevents early postmenopausal bone loss but without a dose-dependent effect. J. Nutr. Biochem. 7: 509-517 (2006)
21. Kim JH, Jeon SM, An MY, Ku SK, Lee JH, Choi MS, Moon KD. Effects of diet of Korean safflower (Carthamus tinctorius L.) seed powder on bone tissue in rats during the recovery of rib fracture. J. Korean Soc. Food Sci. Nutr. 27: 698-704 (1998)
22. Chung SY, Choi HJ, Chung MW, Ann MR, Yoo TM, Rheu HM, Ang JS. Effects of safflower seed on the fracture healing in rat tibia. Yakhak Hoeji 43: 526-534 (1999)
23. Chung SY, Choi HJ, Chung MW, Ahn MR, Yoo TM, Rheu HM, Yang JS. Effects of safflower seed on the fracture healing in rat tibia. Arch. Pharm. Res. 25: 313-317 (2002)
24. Seo HJ, Kim JH, Kwak DY, Jeon SM. The effects of safflower seed powder and its fraction on bone tissue in rib-fractured rats during the recovery. Korean J. Nutr. 33: 411-420 (2000)
25. Yun IH, Cho KJ, Kim DS, Woo HK, Chang HD. Effects of safflower extracts on activation of calcium channel, proliferation of osteoblast, and bone density of osteoporotic patients. Final Report of Agricultural and Fishery Project, Department of Oral Anatomy, School of Dentistry, Pusan National University, Busan, Korea (2002)
26. Bae SJ, Shim SM, Park YJ, Lee JY, Chang EJ, Choi SW. Cytotoxicity of phenolic compounds isolated from seeds of safflower (Carthamus tinctorius L.) on cancer cell lines. Food Sci. Biotechnol. 11: 140-146 (2002)
27. Kim EO, Oh JH, Lee SK, Lee JY, Choi SW. Antioxidant properties and quantification of phenolic compounds from safflower (Carthamus tinctorius L.) seeds. Food Sci. Biotechnol. 16: 71-77 (2007)
28. Kim HJ, Bae YC, Park RW, Choi SW, Cho SH, Lee WJ. Bone-protecting effect of safflower seeds in ovariectomized rats. Calc. Tiss. Int. 71: 88-94 (2002)
29. The American Institute of Nutrition: Report of the American Institute of Nutrition Ad Hoc Committee on standards for nutritional studies. J. Nutr. 107: 1340-1348 (1977)
30. Mosmann TJ. Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays. Immunol. Methods 65: 55-63 (1983)
31. Ramirez ME, McMurry MP, Wiebke GA, Felton KJ, Ren K, Meikle AW, Iverius PH. Evidence for sex steroid inhibition of lipoprotein lipase in men: comparison of abdominal and femoral adipose tissue. Metabolism 46: 179-185 (1997)
32. Valette A, Meignen KM, Mercier L, Liehr JQ Boyer J. Effects of 2-fluoroestradiol on lipid metabolism in the ovariectomized rat. J. Steroid Biochem. 25: 575-578 (1986)
33. Zava DT, Duwe G Estrogenic and antiproliferative properties of genistein and other flavonoids in human breast cancer cells in vitro. Nutr. Cancer 27: 31-40 (1997)
34. Wronski TJ, Walsh CC, Ignaszewskin LA. Histologic evidence for osteopenia and increased bone turn over in ovariectomized rats. Bone 7: 119-123 (1986)
35. Martin RB, Chow BD, Lucas PA. Bone marrow fat content in relation to bpne remodeling and serum chemistry in intact and ovariectomized dogs. Calc. Tiss. Int. 46: 189-194 (1990)
36. Wang GW, Sweet D, Reger S, Thompson R. Fat cell changes as a mechanism of avascular necrosis in the femoral head in cortisone-treated rabbits. J. Bone Joint Surg. Am. 59A: 729-735 (1977)
37. Minaire P, Meunier PJ, Edouard C, Bernard J, Coupron J, Bouret J. Quantitative histological data on disuse osteoporosis. Calc. Tiss. Res. 17: 57-73 (1974)
38. Nuttall ME, Patton AJ, Oliverta DL, Nadeau PD, Gowen ME. Human trabecular bone cells are able to express both osteoblastic and adipocytic phenorype: implications for osteopenic disorders. J. Bone Miner. Res. 13: 371-382 (1998)
39. Beresfbrd JN, Bennett JH, Devlin C, Leboy PS, Owen ME. Evidence for an inverse relationship between the differentiation of adipocytic and osteogenic cells in rat marrow stromal cell culture. J. Cell Sci. 102: 341-351 (1992)
40. Dang ZC, van Bezooijen RL, Karperien M, Papapoulos SE, Mowik CW. Exposure of KS483 cells to estrogen enhances osteogenesis and inhibits adipogenesis. J. Bone Miner. Res. 17: 394-405 (2002)
41. Robinson JA, Harris SA, Riggs BL, Spelsberg TC. Estrogen regulation of human osteoblastic cell proliferation and differentiation. Endocrinology 138: 2919-2927 (1997)
42. Sugimoto E, Yamguchi M. Anabolic effect of genistein in osteoblstic MC3T3-E1 cells. Int. J. Mol. Med. 5: 515-520 (2000)
43. Thompson LU, Orcheson L, Rickard S, Jenab M, Serraino M, Seidl M, Cheung F. Anticancer effects of flaxseed lignans. pp. 356-364. In: Natural Antioxidants and Food Quality in Atherosclerosis and Cancer Prevention. Kumpulainen JT, Salonen JT (eds). The Royal Society of Chemistry, Cambridge, UK (1996)
44. Ward WE, Yuan YV, Cheung AM, Thompson, LU. Exposure to purified lignan from flaxseed (Linum usitatissimum) alters bone development in female rats. Brit. J. Nutr. 86: 499-505 (2001)
45. Gustafsson BI, Westbroek I, Waarsing JH, Waldum H, Solligard E, Brunsvik A, Dimmen S, van Leeuwen JP, Weinans H, Syversen U. Long-term serotonin administration leads to higher bone mineral density, affects bone architecture, and leads to higher femoral bone stiffness in rats. J. Cell. Biochem. 97: 1283-1291 (2006)
46. Wronski TJ, Walsh CC, Ignaszewskin LA. Histologic evidence for osteopenia and increased bone turn over in ovariectomized rats. Bone 7: 119-123 (1986)
47. Taranta A, Brama M, Teti A, Luca VD, Scandurra R, Spera R, Spera Q Agnusdei D, Termine JD, Migliaccio S. The selective estrogen receptor modulator raloxifene regulates osteoclast and osteoblast activity in vitro. Bone 30: 368-376 (2002)
48. Tsutsumi N. Effect of coumestrol on bone metabolism in organ culture. Biol. Pharm. Bull. 18: 1012-1015 (1995)
49. Hagiwara H, Naruse M, Adachi C, Inoue A, Hiruma Y, Otsuka E, Naruse K, Demura H, Hirose S. Ipriflavone down-regulates endothelin receptor levels during differentiation of rat calcarial osteoblast-like cells. J. Biochem. -Tokyo 126: 168-173 (1999)