Estrogen regulation of human osteoblastic cell proliferation and differentiation

Endocrinology

Volumn 138, Issue 7, 1997, Pages 2919-2927

  Robinson, John A ^a   Harris, Steven A ^b   Riggs, B Lawrence ^b   Spelsberg, Thomas C ^a  

^a MAYO GRADUATE SCHOOL   (United States)

^b MAYO CLINIC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ESTROGEN; ESTROGEN RECEPTOR; OSTEOCALCIN;

ARTICLE; BONE ATROPHY; CELL DIFFERENTIATION; CELL PROLIFERATION; GENE EXPRESSION; GENE EXPRESSION REGULATION; HUMAN; HUMAN CELL; MINERALIZATION; NORTHERN BLOTTING; OSTEOBLAST; PRIORITY JOURNAL; PROTEIN EXPRESSION; REGULATORY MECHANISM;

EID: 0030924819     PISSN: 00137227     EISSN: None     Source Type: Journal    
DOI: 10.1210/endo.138.7.5277     Document Type: Article

References (47)

1. Heaney RP, Recker RR, Saville PD 1978 Menopausal changes in bone remodeling. J Lab Clin Med 92:964-970
2. Turner RT, Riggs BL, Speisberg TC 1994 Skeletal effects of ertrogen. Endocr Rev 16:275-300
3. Lindsay R, Hart DM, Aitken JM, MacDonald EB, Anderson JB, Clarke AC 1976 Long-term prevention of postmenopausal osteoporosis by estrogen. Lancet 1:1038-1041
4. Stevenson JC, Cust MP, Gangar KF, Hillard TC, Lees B, Whitehead MI 1990 Effects of transdermal vs. oral hormone replacement therapy on bone density in spine and proximal femur in postmenopausal women. Lancet 336:265-269
5. Lindsay R, Tohme JF 1990 Estrogen treatment of patients with established postmenopausal osteoporosis. Obstet Gynecol 76:290-295
6. Riggs BL, Melton LJ 1986 Medical progress: involutional osteoporosis. N Engl J Med 314:1676-1684
7. Riggs BL, Jowsey J, Goldsmith S, Kelly PJ, Hoffman DL, Arnaud CC 1972 Short and long term effects of estrogen and synthetic anobolic hormones in postmenopausal osteoporesis. J Clin Invest 51:1649-1663
8. Slemenda C, Hui SL, Longcope C, Johnston CC 1987 Sex steroids and bone mass: a study of changes about the time of menopause. J Clin Invest 80:261-269
9. Lindsay R, Hart DM, Forrest C, Baird C 1980 Prevention of spinal osteoporosis in oophorectomized women. Lancet 2:1151-1154
10. Oursler MJ, Osdoby P, Pyfferoen J, Riggs BL, Spelsberg TC 1991 Avian osteoclasts as estrogen target cells. Proc Natl Acad Sci USA 88:6613-6617
11. Turner RT, Backup P, Sherman PJ, Hill E, Evans GL, Spelsberg TC 1992 Mechanism of action of estrogen on intramembranous bone formation: regulation of osteoblast differentiation and activity. Endocrinology 131:883-889
12. Steiniche T, Hasling C, Charles P, Eriksen F, Mosekilde L, Meisen F 1989 A randomized study on the effects of estrogen/gestagen or high dose oral calcium on trabecular bone remodeling in postmenopausal osteoporosis. Bone 10:313-320
13. Prestwood KM, Pilbeam CC, Burleson JA, Woodiel FN, Delmas PD, Deftos LJ, Raisz LG 1994 The short-term effects of conjugated estrogen on bone turnover in older women. J Clin Endocrinol Metab 79:366-371
14. Vedi S, Compston JE 1996 The effects of long-term hormone replacement therapy on bone remodeling in postmenopausal women. Bone 19:535-539
15. Chow J, Tobias H, Colston KW, Chambers TJ 1992 Estrogen maintains trabecular bone volume in rats not only by suppression of bone resorption but also by stimulation of bone formation. J Clin Invest 89:74-78
16. Bain SD, Bailey SC, Celino DL, Lantry MM, Edwards MW 1993 High-dose estrogen inhibits bone resorption and stimulates bone formation in ovariectomized mouse. J Bone Miner Res 8:435-442
17. Takano-Yammato T, Rodan GA 1990 Direct effects of 17β-estradiol on trabecular bone in ovariectomized rats. Proc Natl Acad Sci USA 87:2172-2176
18. Eriksen EF, Colvard DS, Berg NJ, Graham ML, Mann KG, Spelsberg TC, Riggs BL 1980 Evidence of estrogen receptors in normal human osteoblast-like cells. Science 241:84-86
19. Komm BS, Terpening CM, Benz DJ, Graeme KA, Gallegas A, Kore M, Greene GL, O'Mally BW, Haussler MR 1988 Estrogen binding receptor mRNA and biologic response in osteoblast-like osteosarcoma cells. Science 241:81-83
20. Harris SA, Tau KR, Turner RT, Spelsberg TC 1996 Estrogens and progestins. In: Bilezikian JP (ed) Principles of Bone Biology. Academic Press, San Diego, pp 507-520
21. Rickard D, Russell G, Gowen M 1992 Oestradiol inhibits the release of tumor necrosis factor but not interleukin 6 from adult human osteoblasts in vitro. Osteoporosis Int 2:94-102
22. Kassem M, Harris SA, Spelsberg TC, Riggs BL 1996 Estrogen inhibin interleukin-6 production and gene expression in a human osteoblastic cell line with high levels of estrogen receptors. J Bone Miner Res 11:193-199
23. Ernst M, Heath JK, Rodan GA 1989 Estradiol effects on proliferation, messenger ribonucleic acid for collagen and insulin-like growth factor-I, and parathyroid hormone-stimulated adenylate cyclase activity in osteoblastic cells from calvaria and long bones. Endocrinology 125:825-833
24. Bankson DD, Rifai N, Williams ME, Silverman LM, Gray TK 1989 Biochemical effects of 17β-estradiol on UMR106 cells. Bone Miner 6:55-63
25. Scmid C, Ernst M, Zapf J, Froesch ER 1989 Release of insulin-like growth factor carrier proteins by osteoblasts: stimulation by estradiol and growth hormone. Biochem Biophys Res Commun 160:788-794
26. Slater M, Patava J, Kingham K, Bason RS 1994 Modulation of growth factor incorporation into ECM of human osteoblast-like cells in vitro by 17 beta-estradiol. Am J Physiol 267:E990-E1001
27. Chen TL, Liu F, Bates RL, Hintz RL 1991 Further characterization of insulin-like growth factor binding proteins in rat osteoblast-like cell cultures: modulation by 17β-estradiol and human growth hormone. Endocrinology 128:2489-2496
28. Kassem M, Okazaki R, DeLeon D, Harris SA, Robinson JA, Spelsberg TC, Conover CA, Riggs BL 1996 Potential mechanism of estrogen-mediated decrease in bone formation: estrogen increases production of inhibitory insulin-like growht factor-binding protein-4. Proc Assoc Am Physicians 108:155-164
29. Oursler MJ, Cortese C, Keeting P, Anderson MA, Bonde S, Riggs BL, Spelsberg TC 1991 Modulation of transforming growth factor-β production in normal human osteoblast-like cells by 17β-estradiol and parathyroid hormone. Endocrinology 129:3313-3320
30. Davis VL, Couse JF, Gray TK, Korach KS 1994 Correlation between low levels of estrogen receptors and estrogen responsiveness in two rat osteblast-like cell lines. J Bone Miner Res 9:983-991
31. Harris SA, Tau KR, Enger RJ, Toft DO, Riggs BL, Spelsberg TC 1995 Estrogen response in the hFOB1.19 human fetal osteoblastic cell line stably transfected with the human estrogen receptor gene. J Cell Biochem 59:193-201
32. Harris SA, Enger RJ, Riggs BL, Spelsberg TC 1995 Development and characterization of a contitionally immortalized human fetal osteoblastic cell line. J Bone Miner Res 10:178-186
33. Benz WW, Getz MJ, Wells DL, Moses HL 1977 Nuclear RNA polymerase activities and poly(A)-containing mRNA accumulation in cultured AKR mouse embryo cells stimulated to proliferate. Exp Cell Res 108:157-165
34. Schenk RK, Olah AJ, Herrmann W 1984 Preparation of calcified tissues for light microscopy. In: Dickson GR (ed) Methods of Calcified Tissue Preparation. Elsevier, New York, p 1
35. Chomczynski PA 1993 A reagent for the single-step simultaneous isolation of RNA, DNA, and protein from cell and tissue samples. Biotechniques 15:532-536
36. McMaster GK, Carmichael GG 1977 Analysis of single- and double-stranded nucleic acids on polyacrylamide and agarose gels by glyoxal and acrinine orange. Proc Natl Acad Sci USA 74:4835-4838
37. Owen TA, Aronow M, Shalhoub V, Barone LM, Wilming L, Tassssinali MS, Kennedy M, PockWinse S, Lian JB, Stein GS 1990 Progressive development of the rat osteoblast phenotype in vitro: reciprocal relationship in expression of genes associated with osteoblast proliferation and differentiation during formation of bone extracellular matrix. J Cell Physiol 143:420-430
38. Spelsberg TC, Harris SA, Riggs BL 1995 Immortalized osteoblast cell systems (new human fetal osteoblast systems). Calcif Tissue Int 56:518-521
39. Okazaki R, Conover CA, Harris SA, Spelsberg TC, Riggs BL 1995 Normal human osteoblast-like cells consistently express genes for insulin-like growth factors I and II but transformed human osteoblast cell lines do not. J Bone Miner Res 10:788-795
40. Huo B, Dossing DA, Dimuzio MT 1995 Generation and characterization of a human osteosarcoma cell line stably transfected with the human estrogen receptor gene. J Bone Miner Res 10:769-781
41. Watts CKW, King RJB 1994 Overexpression of estrogen receptor in HTB 96 human osteosarcoma cells results in estrogen-induced growth inhibition and receptor cross talk. J Bone Miner Res 9:1251-1266
42. Chalbos D, Philips A, Rochefort H 1994 Genomic cross-talk between the estrogen receptor and growth factor regulatory pathways in estrogen target tissues. Semin Cancer Biol 5:361-368
43. Levenson AS, Jordan VC 1994 Transfection of human estrogen receptor (ER) cDNA into ER-negative mammalian cell lines. J Steroid Biochem Mol Biol 51:229-239
44. Turner RT, Colvard DS, Spelsberg TC 1990 Estrogen inhibition of periosteal bone formation in rat long bones: down regulation of gene expression for bone matrix proteins. Endocrinology 127:1346-1351
45. McDonnell DP, Clenn DL, Hermann T, Goldman ME, Pike JW 1995 Analysis of estrogen receptor function in vitro reveal three distinct classes of antiestrogens. Mol Endocrinol 9:659-669
46. Waters MR 1995 Newly identified action of the vitamin D endocrine system. Endocr Rev Monogr 4:1-46
47. Turner RT, Kapelner SN, Spelsberg TC 1992 Tissue-specific expression of bone proteins in femora of growing rats. Am J Physiol 263:E724-E729