메뉴 건너뛰기




Volumn 13, Issue 3, 2008, Pages 157-174

Review: An overview of the extra-lipid effects of rosuvastatin

Author keywords

Atherosclerosis; Extra lipid effects; Pleiotropic effects; Rosuvastatin; Safety

Indexed keywords

CANDESARTAN; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; LOW DENSITY LIPOPROTEIN; LOW DENSITY LIPOPROTEIN CHOLESTEROL; MEVALONIC ACID; N(G) NITROARGININE METHYL ESTER; ROSUVASTATIN; CARDIOTONIC AGENT; FIBRINOLYTIC AGENT; FLUOROBENZENE; PYRIMIDINE DERIVATIVE; SULFONAMIDE;

EID: 49749115773     PISSN: 10742484     EISSN: None     Source Type: Journal    
DOI: 10.1177/1074248408318628     Document Type: Review
Times cited : (69)

References (130)
  • 1
    • 26444578943 scopus 로고    scopus 로고
    • The statin studies: From targeting hypercholesterolaemia to targeting the high-risk patient
    • Ong HT The statin studies: from targeting hypercholesterolaemia to targeting the high-risk patient. QJM. 2005 ; 98: 599-614.
    • (2005) QJM , vol.98 , pp. 599-614
    • Ong, H.T.1
  • 2
    • 0037420492 scopus 로고    scopus 로고
    • For the ASCOT Investigators. Prevention of coronary and stroke events with atorvastatin in hypertensive patients who have average or lower-than-average cholesterol concentrations, in the Anglo-Scandinavian Cardiac Outcomes Trial-Lipid Lowering Arm (ASCOT-LLA): A multicentre randomized controlled trial
    • Sever PS DB, Poulter NR, Wedel H., et al, for the ASCOT Investigators. Prevention of coronary and stroke events with atorvastatin in hypertensive patients who have average or lower-than-average cholesterol concentrations, in the Anglo-Scandinavian Cardiac Outcomes Trial-Lipid Lowering Arm (ASCOT-LLA): a multicentre randomized controlled trial. Lancet. 2003 ; 361: 1149-1158.
    • (2003) Lancet , vol.361 , pp. 1149-1158
    • Sever, P.S.D.B.1    Poulter, N.R.2    Wedel, H.3
  • 3
    • 15944410609 scopus 로고    scopus 로고
    • For the Treating to New Targets (TNT) Investigators. Intensive lipid lowering with atorvastatin in patients with stable coronary disease
    • LaRosa JC, Grundy SM, Waters DD, et al, for the Treating to New Targets (TNT) Investigators. Intensive lipid lowering with atorvastatin in patients with stable coronary disease. N Engl J Med. 2005 ; 352: 1-11.
    • (2005) N Engl J Med , vol.352 , pp. 1-11
    • Larosa, J.C.1    Grundy, S.M.2    Waters, D.D.3
  • 4
    • 26244432388 scopus 로고    scopus 로고
    • Efficacy and safety of cholesterol-lowering treatment: Prospective meta-analysis of data from 90,056 participants in 14 randomised trials of statins
    • Baigent C., Keech A., Kearney PM, et al. Efficacy and safety of cholesterol-lowering treatment: prospective meta-analysis of data from 90,056 participants in 14 randomised trials of statins. Lancet. 2005 ; 366: 1267-1278.
    • (2005) Lancet , vol.366 , pp. 1267-1278
    • Baigent, C.1    Keech, A.2    Kearney, P.M.3
  • 5
    • 33646829645 scopus 로고    scopus 로고
    • Efficacy of lipid lowering drug treatment for diabetic and nondiabetic patients: Meta-analysis of randomised controlled trials
    • Costa J., Borges M., David C., Vaz Carneiro A. Efficacy of lipid lowering drug treatment for diabetic and nondiabetic patients: meta-analysis of randomised controlled trials. BMJ. 2006 ; 332: 1115-1124.
    • (2006) BMJ , vol.332 , pp. 1115-1124
    • Costa, J.1    Borges, M.2    David, C.3    Vaz Carneiro, A.4
  • 6
    • 0032554676 scopus 로고    scopus 로고
    • Influence of pravastatin and plasma lipids on clinical events in the West of Scotland Coronary Prevention Study (WOSCOPS)
    • WOSCOPS Study Group. Influence of pravastatin and plasma lipids on clinical events in the West of Scotland Coronary Prevention Study (WOSCOPS). Circulation. 1998 ; 97: 1440-1445.
    • (1998) Circulation , vol.97 , pp. 1440-1445
    • Study Group, W.1
  • 7
    • 23944445364 scopus 로고    scopus 로고
    • Effects of statins on 3-hydroxy-3-methylglutaryl coenzyme a reductase inhibition beyond low-density lipoprotein cholesterol
    • Liao JK Effects of statins on 3-hydroxy-3-methylglutaryl coenzyme a reductase inhibition beyond low-density lipoprotein cholesterol. Am J Cardiol. 2005 ; 96: 24F - 33F.
    • (2005) Am J Cardiol , vol.96
    • Liao, J.K.1
  • 10
    • 33751180331 scopus 로고    scopus 로고
    • Beyond lipid lowering: What have we learned about the benefits of statins from the acute coronary syndromes trials?
    • Ray KK, Cannon CP, Ganz P. Beyond lipid lowering: What have we learned about the benefits of statins from the acute coronary syndromes trials? Am J Cardiol. 2006 ; 98: 18P - 25P.
    • (2006) Am J Cardiol , vol.98
    • Ray, K.K.1    Cannon, C.P.2    Ganz, P.3
  • 11
    • 0038645309 scopus 로고    scopus 로고
    • Comparison of the efficacy and safety of rosuvastatin versus atorvastatin, simvastatin, and pravastatin across doses (STELLAR* Trial)
    • Jones PH, Davidson MH, Stein EA, et al. Comparison of the efficacy and safety of rosuvastatin versus atorvastatin, simvastatin, and pravastatin across doses (STELLAR* Trial). Am J Cardiol. 2003 ; 92: 152-160.
    • (2003) Am J Cardiol , vol.92 , pp. 152-160
    • Ph, J.1    Davidson, M.H.2    Stein, E.A.3
  • 12
    • 11844302289 scopus 로고    scopus 로고
    • Twelve-week, multicenter, randomized, open-label comparison of the effects of rosuvastatin 10 mg/d and atorvastatin 10 mg/d in high-risk adults: A DISCOVERY study
    • Strandberg TE, Feely J., Sigurdsson EL Twelve-week, multicenter, randomized, open-label comparison of the effects of rosuvastatin 10 mg/d and atorvastatin 10 mg/d in high-risk adults: a DISCOVERY study. Clin Ther. 2004 ; 26: 1821-1833.
    • (2004) Clin Ther , vol.26 , pp. 1821-1833
    • Strandberg, T.E.1    Feely, J.2    El, S.3
  • 13
    • 33845987739 scopus 로고    scopus 로고
    • Expanding options with a wider range of rosuvastatin doses
    • Olsson A. Expanding options with a wider range of rosuvastatin doses. Clin Ther. 2006 ; 28: 1747-1763.
    • (2006) Clin Ther , vol.28 , pp. 1747-1763
    • Olsson, A.1
  • 14
    • 33947651074 scopus 로고    scopus 로고
    • The GALAXY Program: An update on studies investigating efficacy and tolerability of rosuvastatin for reducing cardiovascular risk
    • Schuster H. The GALAXY Program: an update on studies investigating efficacy and tolerability of rosuvastatin for reducing cardiovascular risk. Expert Rev Cardiovasc Ther. 2007 ; 5: 177-193.
    • (2007) Expert Rev Cardiovasc Ther , vol.5 , pp. 177-193
    • Schuster, H.1
  • 15
    • 0141560665 scopus 로고    scopus 로고
    • Comparative pharmacology of rosuvastatin
    • McTaggart F. Comparative pharmacology of rosuvastatin. Atheroscler Suppl. 2003 ; 4: 9-14.
    • (2003) Atheroscler Suppl , vol.4 , pp. 9-14
    • McTaggart, F.1
  • 16
    • 33947713026 scopus 로고    scopus 로고
    • Effect of rosuvastatin on progression of carotid intima-media thickness in low-risk individuals with subclinical atherosclerosis: The METEOR Trial
    • Crouse JR 3rd, Raichlen JS, Riley WA, et al. Effect of rosuvastatin on progression of carotid intima-media thickness in low-risk individuals with subclinical atherosclerosis: the METEOR Trial. JAMA. 2007 ; 297: 1344-1353.
    • (2007) JAMA , vol.297 , pp. 1344-1353
    • Crouse III, J.R.1    Raichlen, J.S.2    Riley, W.A.3
  • 17
    • 33645524176 scopus 로고    scopus 로고
    • Effect of very high-intensity statin therapy on regression of coronary atherosclerosis: The ASTEROID trial
    • Nissen SE, Nicholls SJ, Sipahi I., et al. Effect of very high-intensity statin therapy on regression of coronary atherosclerosis: the ASTEROID trial. JAMA. 2006 ; 295: 1556-1565.
    • (2006) JAMA , vol.295 , pp. 1556-1565
    • Nissen, S.E.1    Nicholls, S.J.2    Sipahi, I.3
  • 18
    • 18244362843 scopus 로고    scopus 로고
    • Rosuvastatin reduces platelet activation in heart failure: Role of NO bioavailability
    • Schafer A., Fraccarollo D., Eigenthaler M., et al. Rosuvastatin reduces platelet activation in heart failure: role of NO bioavailability. Arterioscler Thromb Vasc Biol. 2005 ; 25: 1071-1077.
    • (2005) Arterioscler Thromb Vasc Biol , vol.25 , pp. 1071-1077
    • Schafer, A.1    Fraccarollo, D.2    Eigenthaler, M.3
  • 19
    • 25444501302 scopus 로고    scopus 로고
    • Effects of rosuvastatin on endothelial function in patients with familial combined hyperlipidaemia (FCH)
    • ter Avest E., Abbink EJ, Holewijn S., de Graaf J., Tack CJ, Stalenhoef AF Effects of rosuvastatin on endothelial function in patients with familial combined hyperlipidaemia (FCH). Curr Med Res Opin. 2005 ; 21: 1469-1476.
    • (2005) Curr Med Res Opin , vol.21 , pp. 1469-1476
    • Ter Avest, E.1    Abbink, E.J.2    Holewijn, S.3    De Graaf, J.4    Tack, C.J.5    Stalenhoef, A.F.6
  • 20
    • 0041820000 scopus 로고    scopus 로고
    • Effects of rosuvastatin on nitric oxide-dependent function in aorta and corpus cavernosum of diabetic mice: Relationship to cholesterol biosynthesis pathway inhibition and lipid lowering
    • Nangle MR, Cotter MA, Cameron NE Effects of rosuvastatin on nitric oxide-dependent function in aorta and corpus cavernosum of diabetic mice: relationship to cholesterol biosynthesis pathway inhibition and lipid lowering. Diabetes. 2003 ; 52: 2396-2402.
    • (2003) Diabetes , vol.52 , pp. 2396-2402
    • Nangle, M.R.1    Ma, C.2    Cameron, N.E.3
  • 21
    • 3042738127 scopus 로고    scopus 로고
    • Rosuvastatin treatment reverses impaired coronary artery vasodilation in fructose-fed, insulin-resistant rats
    • Miller AW, Tulbert CD, Busija DW Rosuvastatin treatment reverses impaired coronary artery vasodilation in fructose-fed, insulin-resistant rats. Am J Physiol Regul Integr Comp Physiol. 2004 ; 287: R157 - R160.
    • (2004) Am J Physiol Regul Integr Comp Physiol , vol.287
    • Miller, A.W.1    Tulbert, C.D.2    Busija, D.W.3
  • 22
    • 33947378811 scopus 로고    scopus 로고
    • Improved endothelial function and reduced platelet activation by chronic HMG-CoA-reductase inhibition with rosuvastatin in rats with streptozotocin- induced diabetes mellitus
    • Schafer A., Fraccarollo D., Vogt C., et al. Improved endothelial function and reduced platelet activation by chronic HMG-CoA-reductase inhibition with rosuvastatin in rats with streptozotocin-induced diabetes mellitus. Biochem Pharmacol. 2007 ; 73: 1367-1375.
    • (2007) Biochem Pharmacol , vol.73 , pp. 1367-1375
    • Schafer, A.1    Fraccarollo, D.2    Vogt, C.3
  • 23
    • 33747171728 scopus 로고    scopus 로고
    • Effect of therapy with rosuvastatin on lipid spectrum, factors of inflammation and endothelial function in patients with ischemic heart disease
    • Sergienko IV, Samoilenko E., Masenko VP, et al. Effect of therapy with rosuvastatin on lipid spectrum, factors of inflammation and endothelial function in patients with ischemic heart disease. Kardiologiia. 2006 ; 46: 4-8.
    • (2006) Kardiologiia , vol.46 , pp. 4-8
    • Sergienko, I.V.1    Samoilenko, E.2    Masenko, V.P.3
  • 24
    • 3142606890 scopus 로고    scopus 로고
    • Effect of rosuvastatin on plasma levels of asymmetric dimethylarginine in patients with hypercholesterolemia
    • Lu TM, Ding YA, Leu HB, Yin WH, Sheu WH, Chu KM Effect of rosuvastatin on plasma levels of asymmetric dimethylarginine in patients with hypercholesterolemia. Am J Cardiol. 2004 ; 94: 157-161.
    • (2004) Am J Cardiol , vol.94 , pp. 157-161
    • Lu, T.M.1    Ya, D.2    Leu, H.B.3    Yin, W.H.4    Sheu, W.H.5    Chu, K.M.6
  • 25
    • 40349115867 scopus 로고    scopus 로고
    • Rosuvastatin attenuates angiotensin II-induced neointimal formation after stent implantation in the rat
    • van der Harst P., Groenwegen HC, Roks AJ, et al. Rosuvastatin attenuates angiotensin II-induced neointimal formation after stent implantation in the rat. Coron Artery Dis. 2008 ; 19: 47-53.
    • (2008) Coron Artery Dis , vol.19 , pp. 47-53
    • Van Der Harst, P.1    Groenwegen, H.C.2    Roks, A.J.3
  • 26
    • 0035960605 scopus 로고    scopus 로고
    • Oxidant stress as a marker for cardiovascular events: Ox marks the spot
    • Landmesser U., Harrison DG Oxidant stress as a marker for cardiovascular events: Ox marks the spot. Circulation. 2001 ; 104: 2638-2640.
    • (2001) Circulation , vol.104 , pp. 2638-2640
    • Landmesser, U.1    Harrison, D.G.2
  • 27
    • 34948842028 scopus 로고    scopus 로고
    • Isoprenoid depletion by statins antagonizes cytokine-induced down-regulation of endothelial nitric oxide expression and increases NO synthase activity in human umbilical vein endothelial cells
    • Jantzen F., Koneman S., Wolff B., et al. Isoprenoid depletion by statins antagonizes cytokine-induced down-regulation of endothelial nitric oxide expression and increases NO synthase activity in human umbilical vein endothelial cells. J Physiol Pharmacol. 2007 ; 58: 503-514.
    • (2007) J Physiol Pharmacol , vol.58 , pp. 503-514
    • Jantzen, F.1    Koneman, S.2    Wolff, B.3
  • 28
    • 33644784922 scopus 로고    scopus 로고
    • Statins prevent dextrose-induced endothelial barrier dysfunction, possibly through inhibition of superoxide formation
    • Haas MJ, Horani MH, Parseghian SA, Mooradian AD Statins prevent dextrose-induced endothelial barrier dysfunction, possibly through inhibition of superoxide formation. Diabetes. 2006 ; 55: 474-479.
    • (2006) Diabetes , vol.55 , pp. 474-479
    • Haas, M.J.1    Horani, M.H.2    Parseghian, S.A.3    Mooradian, A.D.4
  • 29
    • 30044433591 scopus 로고    scopus 로고
    • Cross-talk between dyslipidemia and renin-angiotensin system and the role of LOX-1 and MAPK in atherogenesis studies with the combined use of rosuvastatin and candesartan
    • Chen J., Li D., Schaefer R., Mehta JL Cross-talk between dyslipidemia and renin-angiotensin system and the role of LOX-1 and MAPK in atherogenesis studies with the combined use of rosuvastatin and candesartan. Atherosclerosis. 2006 ; 184: 295-301.
    • (2006) Atherosclerosis , vol.184 , pp. 295-301
    • Chen, J.1    Li, D.2    Schaefer, R.3    Mehta, J.L.4
  • 30
    • 58049180113 scopus 로고    scopus 로고
    • Rosuvastatin prevents endothelial cell death and reduces atherosclerotic lesion formation in ApoE-deficient mice [published online ahead of print December 10, 2007]
    • Enomoto S., Sata M., Fukuda D., Nakamura K., Nagai R. Rosuvastatin prevents endothelial cell death and reduces atherosclerotic lesion formation in ApoE-deficient mice [published online ahead of print December 10, 2007]. Biomed Pharmacother. doi:10.1016/j.biopha.2007.11.002.
    • Biomed Pharmacother
    • Enomoto, S.1    Sata, M.2    Fukuda, D.3    Nakamura, K.4    Nagai, R.5
  • 31
    • 37849040502 scopus 로고    scopus 로고
    • Rosuvastatin increases vascular endothelial PPARgamma expression and corrects blood pressure variability in obese dyslipidaemic mice
    • Desjardins F., Sekkali B., Verreth W., et al. Rosuvastatin increases vascular endothelial PPARgamma expression and corrects blood pressure variability in obese dyslipidaemic mice. Eur Heart J. 2008 ; 29: 128-137.
    • (2008) Eur Heart J , vol.29 , pp. 128-137
    • Desjardins, F.1    Sekkali, B.2    Verreth, W.3
  • 32
    • 24144465868 scopus 로고    scopus 로고
    • Effect of rosuvastatin on insulin sensitivity in patients with familial combined hyperlipidaemia
    • ter Avest E., Abbink EJ, de Graaf J., Tack CJ, Stalenhoef AF Effect of rosuvastatin on insulin sensitivity in patients with familial combined hyperlipidaemia. Eur J Clin Invest. 2005 ; 35: 558-564.
    • (2005) Eur J Clin Invest , vol.35 , pp. 558-564
    • Ter Avest, E.1    Abbink, E.J.2    De Graaf, J.3    Tack, C.J.4    Stalenhoef, A.F.5
  • 33
    • 33644891902 scopus 로고    scopus 로고
    • Reduction of oxidative stress and modulation of autoantibodies against modified low-density lipoprotein after rosuvastatin therapy
    • Resch U., Tatzber F., Budinsky A., Sinzinger H. Reduction of oxidative stress and modulation of autoantibodies against modified low-density lipoprotein after rosuvastatin therapy. Br J Clin Pharmacol. 2006 ; 61: 262-274.
    • (2006) Br J Clin Pharmacol , vol.61 , pp. 262-274
    • Resch, U.1    Tatzber, F.2    Budinsky, A.3    Sinzinger, H.4
  • 34
    • 33745066138 scopus 로고    scopus 로고
    • Rosuvastatin treatment protects against nitrate-induced oxidative stress in eNOS knockout mice: Implication of the NAD(P)H oxidase pathway
    • Otto A., Fontaine J., Tschirhart E., Fontaine D., Berkenboom G. Rosuvastatin treatment protects against nitrate-induced oxidative stress in eNOS knockout mice: implication of the NAD(P)H oxidase pathway. Br J Pharmacol. 2006 ; 148: 544-552.
    • (2006) Br J Pharmacol , vol.148 , pp. 544-552
    • Otto, A.1    Fontaine, J.2    Tschirhart, E.3    Fontaine, D.4    Berkenboom, G.5
  • 35
    • 23044445561 scopus 로고    scopus 로고
    • Rosuvastatin treatment protects against nitrate-induced oxidative stress
    • Otto A., Fontaine D., Fontaine J., Berkenboom G. Rosuvastatin treatment protects against nitrate-induced oxidative stress. J Cardiovasc Pharmacol. 2005 ; 46: 177-184.
    • (2005) J Cardiovasc Pharmacol , vol.46 , pp. 177-184
    • Otto, A.1    Fontaine, D.2    Fontaine, J.3    Berkenboom, G.4
  • 36
    • 18044385575 scopus 로고    scopus 로고
    • Rosuvastatin attenuates monocyte-endothelial cell interactions and vascular free radical production in hypercholesterolemic mice
    • Li W., Asagami T., Matsushita H., Lee KH, Tsao PS Rosuvastatin attenuates monocyte-endothelial cell interactions and vascular free radical production in hypercholesterolemic mice. J Pharmacol Exp Ther. 2005 ; 313: 557-562.
    • (2005) J Pharmacol Exp Ther , vol.313 , pp. 557-562
    • Li, W.1    Asagami, T.2    Matsushita, H.3    Kh, L.4    Tsao, P.S.5
  • 37
    • 36348957437 scopus 로고    scopus 로고
    • Statin treatment increases formation of carbon monoxide and bilirubin in mice: A novel mechanism of in vivo antioxidant protection
    • Muchova L., Wong RJ, Hsu M., et al. Statin treatment increases formation of carbon monoxide and bilirubin in mice: a novel mechanism of in vivo antioxidant protection. Can J Physiol Pharmacol. 2007 ; 85: 800-810.
    • (2007) Can J Physiol Pharmacol , vol.85 , pp. 800-810
    • Muchova, L.1    Wong, R.J.2    Hsu, M.3
  • 38
    • 36048985355 scopus 로고    scopus 로고
    • Effect of rosuvastatin versus atorvastatin treatment on paraoxonase-1 activity in men with established cardiovascular disease and a low HDL-cholesterol
    • Bergheanu SC, van Tol A., Dallinga-Thie GM, et al. Effect of rosuvastatin versus atorvastatin treatment on paraoxonase-1 activity in men with established cardiovascular disease and a low HDL-cholesterol. Curr Med Res Opin. 2007 ; 23: 2235-2240.
    • (2007) Curr Med Res Opin , vol.23 , pp. 2235-2240
    • Bergheanu, S.C.1    Van Tol, A.2    Dallinga-Thie, G.M.3
  • 39
    • 33845616263 scopus 로고    scopus 로고
    • Antioxidant and antiplatelet effects of rosuvastatin in a hamster model of prediabetes
    • Miersch S., Sliskovic I., Raturi A., Mutus B. Antioxidant and antiplatelet effects of rosuvastatin in a hamster model of prediabetes. Free Radic Biol Med. 2007 ; 42: 270-279.
    • (2007) Free Radic Biol Med , vol.42 , pp. 270-279
    • Miersch, S.1    Sliskovic, I.2    Raturi, A.3    Mutus, B.4
  • 40
    • 47649111727 scopus 로고    scopus 로고
    • Rosuvastatin protects against oxidative stress and DNA damage in vitro via upregulation of glutathione synthesis [published online ahead of print December 21, 2007]
    • Schupp N., Schmid U., Heidland A., Stopper H. Rosuvastatin protects against oxidative stress and DNA damage in vitro via upregulation of glutathione synthesis [published online ahead of print December 21, 2007]. Atherosclerosis. doi:10.1016/j.atherosclerosis.2007.11.016.
    • Atherosclerosis
    • Schupp, N.1    Schmid, U.2    Heidland, A.3    Stopper, H.4
  • 41
    • 8444233164 scopus 로고    scopus 로고
    • Rosuvastatin upregulates the antioxidant defense protein heme oxygenase-1
    • Grosser N., Erdmann K., Hemmerle A., et al. Rosuvastatin upregulates the antioxidant defense protein heme oxygenase-1. Biochem Biophys Res Commun. 2004 ; 325: 871-876.
    • (2004) Biochem Biophys Res Commun , vol.325 , pp. 871-876
    • Grosser, N.1    Erdmann, K.2    Hemmerle, A.3
  • 42
    • 34447525009 scopus 로고    scopus 로고
    • Effects of rosuvastatin on 3-nitrotyrosine and aortic stiffness in hypercholesterolemia
    • Pirro M., Schillaci G., Mannarino MR, et al. Effects of rosuvastatin on 3-nitrotyrosine and aortic stiffness in hypercholesterolemia. Nutr Metab Cardiovasc Dis. 2007 ; 17: 436-441.
    • (2007) Nutr Metab Cardiovasc Dis , vol.17 , pp. 436-441
    • Pirro, M.1    Schillaci, G.2    Mannarino, M.R.3
  • 43
    • 33750531657 scopus 로고    scopus 로고
    • Lipid-altering efficacy of the ezetimibe/simvastatin single tablet versus rosuvastatin in hypercholesterolemic patients
    • Catapano AL, Davidson MH, Ballantyne CM, et al. Lipid-altering efficacy of the ezetimibe/simvastatin single tablet versus rosuvastatin in hypercholesterolemic patients. Curr Med Res Opin. 2006 ; 22: 2041-2053.
    • (2006) Curr Med Res Opin , vol.22 , pp. 2041-2053
    • Catapano, A.L.1    Davidson, M.H.2    Ballantyne, C.M.3
  • 44
    • 25644455999 scopus 로고    scopus 로고
    • Starting with rosuvastatin in primary hyperlipidemia-is there more than lipid lowering
    • Milionis HJ, Gazi IF, Filippatos TD, et al. Starting with rosuvastatin in primary hyperlipidemia-is there more than lipid lowering ? Angiology. 2005 ; 56: 585-592.
    • (2005) Angiology , vol.56 , pp. 585-592
    • Milionis, H.J.1    Gazi, I.F.2    Filippatos, T.D.3
  • 45
    • 33745714077 scopus 로고    scopus 로고
    • Treating to target patients with primary hyperlipidaemia: Comparison of the effects of ATOrvastatin and ROSuvastatin (the ATOROS study)
    • Milionis HJ, Rizos E., Kostapanos M., et al. Treating to target patients with primary hyperlipidaemia: comparison of the effects of ATOrvastatin and ROSuvastatin (the ATOROS study). Curr Med Res Opin. 2006 ; 22: 1123-1131.
    • (2006) Curr Med Res Opin , vol.22 , pp. 1123-1131
    • Milionis, H.J.1    Rizos, E.2    Kostapanos, M.3
  • 46
    • 33846593363 scopus 로고    scopus 로고
    • Rosuvastatin affecting aortic valve endothelium to slow the progression of aortic stenosis
    • Moura LM, Ramos SF, Zamorano JL, et al. Rosuvastatin affecting aortic valve endothelium to slow the progression of aortic stenosis. J Am Coll Cardiol. 2007 ; 49: 554-561.
    • (2007) J Am Coll Cardiol , vol.49 , pp. 554-561
    • Moura, L.M.1    Ramos, S.F.2    Zamorano, J.L.3
  • 47
    • 0242694573 scopus 로고    scopus 로고
    • Rosuvastatin in the primary prevention of cardiovascular disease among patients with low levels of low-density lipoprotein cholesterol and elevated high-sensitivity C-reactive protein: Rationale and design of the JUPITER trial
    • Ridker PM Rosuvastatin in the primary prevention of cardiovascular disease among patients with low levels of low-density lipoprotein cholesterol and elevated high-sensitivity C-reactive protein: rationale and design of the JUPITER trial. Circulation. 2003 ; 108: 2292-2297.
    • (2003) Circulation , vol.108 , pp. 2292-2297
    • Ridker, P.M.1
  • 48
    • 0141430989 scopus 로고    scopus 로고
    • Rosuvastatin reduces atherosclerosis development beyond and independent of its plasma cholesterol-lowering effect in APOE*3-Leiden transgenic mice: Evidence for antiinflammatory effects of rosuvastatin
    • Kleemann R., Princen HM, Emeis JJ, et al. Rosuvastatin reduces atherosclerosis development beyond and independent of its plasma cholesterol-lowering effect in APOE*3-Leiden transgenic mice: evidence for antiinflammatory effects of rosuvastatin. Circulation. 2003 ; 108: 1368-1374.
    • (2003) Circulation , vol.108 , pp. 1368-1374
    • Kleemann, R.1    Princen, H.M.2    Emeis, J.J.3
  • 49
    • 35148866515 scopus 로고    scopus 로고
    • Differential effect of hypolipidaemic drugs on lipoprotein-associated phospholipase A2
    • Saougos VG, Tambaki AP, Kalogirou M., et al. Differential effect of hypolipidaemic drugs on lipoprotein-associated phospholipase A2. Arterioscler Thromb Vasc Biol. 2007 ; 27: 2236-2243.
    • (2007) Arterioscler Thromb Vasc Biol , vol.27 , pp. 2236-2243
    • Saougos, V.G.1    Tambaki, A.P.2    Kalogirou, M.3
  • 50
    • 37349012116 scopus 로고    scopus 로고
    • Effect of rosuvastatin treatment on plasma visfatin levels in patients with primary hyperlipidemia
    • Kostapanos MS, Derdemezis CS, Filippatos TD, et al. Effect of rosuvastatin treatment on plasma visfatin levels in patients with primary hyperlipidemia. Eur J Pharmacol. 2007 ; 578: 249-252.
    • (2007) Eur J Pharmacol , vol.578 , pp. 249-252
    • Kostapanos, M.S.1    Derdemezis, C.S.2    Filippatos, T.D.3
  • 51
    • 33845642742 scopus 로고    scopus 로고
    • Rapid immunomodulation by rosuvastatin in patients with acute coronary syndrome
    • Link A., Ayadhi T., Bohm M., Nickenig G. Rapid immunomodulation by rosuvastatin in patients with acute coronary syndrome. Eur Heart J. 2006 ; 27: 2945-2955.
    • (2006) Eur Heart J , vol.27 , pp. 2945-2955
    • Link, A.1    Ayadhi, T.2    Bohm, M.3    Nickenig, G.4
  • 52
    • 34347244912 scopus 로고    scopus 로고
    • Rosuvastatin suppresses the inflammatory responses through inhibition of c-Jun N-terminal kinase and Nuclear Factor-kappaB in endothelial cells
    • Kim YS, Ahn Y., Hong MH, et al. Rosuvastatin suppresses the inflammatory responses through inhibition of c-Jun N-terminal kinase and Nuclear Factor-kappaB in endothelial cells. J Cardiovasc Pharmacol. 2007 ; 49: 376-383.
    • (2007) J Cardiovasc Pharmacol , vol.49 , pp. 376-383
    • Kim, Y.S.1    Ahn, Y.2    Hong, M.H.3
  • 53
    • 33644542699 scopus 로고    scopus 로고
    • Effects of rosuvastatin on postprandial leukocytes in mildly hyperlipidemic patients with premature coronary sclerosis
    • van Oostrom AJ, Plokker HW, van Asbeck BS, et al. Effects of rosuvastatin on postprandial leukocytes in mildly hyperlipidemic patients with premature coronary sclerosis. Atherosclerosis. 2006 ; 185: 331-339.
    • (2006) Atherosclerosis , vol.185 , pp. 331-339
    • Van Oostrom, A.J.1    Plokker, H.W.2    Van Asbeck, B.S.3
  • 54
    • 4644372391 scopus 로고    scopus 로고
    • Inhibitory effect of candesartan and rosuvastatin on CD40 and MMPs expression in apo-E knockout mice: Novel insights into the role of RAS and dyslipidemia in atherogenesis
    • Chen J., Li D., Schaefer RF, Mehta JL Inhibitory effect of candesartan and rosuvastatin on CD40 and MMPs expression in apo-E knockout mice: novel insights into the role of RAS and dyslipidemia in atherogenesis. J Cardiovasc Pharmacol. 2004 ; 44: 446-452.
    • (2004) J Cardiovasc Pharmacol , vol.44 , pp. 446-452
    • Chen, J.1    Li, D.2    Schaefer, R.F.3    Mehta, J.L.4
  • 55
    • 38149082716 scopus 로고    scopus 로고
    • Invivo effects of simvastatin and rosuvastatin on global gene expression in peripheral blood leucocytes in a human inflammation model
    • Schmidt WM, Spiel AO, Jilma B., Wolzt M., Müller M. Invivo effects of simvastatin and rosuvastatin on global gene expression in peripheral blood leucocytes in a human inflammation model. Pharmacogenet Genomics. 2008 ; 18: 109-120.
    • (2008) Pharmacogenet Genomics , vol.18 , pp. 109-120
    • Schmidt, W.M.1    Spiel, A.O.2    Jilma, B.3    Wolzt, M.4    Müller, M.5
  • 56
    • 34147152963 scopus 로고    scopus 로고
    • Rosuvastatin displays anti-atherothrombotic and anti-inflammatory properties in apoE-deficient mice
    • Monetti M., Canavesi M., Camera M., et al. Rosuvastatin displays anti-atherothrombotic and anti-inflammatory properties in apoE-deficient mice. Pharmacol Res. 2007 ; 55: 441-449.
    • (2007) Pharmacol Res , vol.55 , pp. 441-449
    • Monetti, M.1    Canavesi, M.2    Camera, M.3
  • 57
    • 0034753831 scopus 로고    scopus 로고
    • A new HMG-CoA reductase inhibitor, rosuvastatin, exerts anti-inflammatory effects on the microvascular endothelium: The role of mevalonic acid
    • Stalker TJ, Lefer AM, Scalia R. A new HMG-CoA reductase inhibitor, rosuvastatin, exerts anti-inflammatory effects on the microvascular endothelium: the role of mevalonic acid. Br J Pharmacol. 2001 ; 133: 406-412.
    • (2001) Br J Pharmacol , vol.133 , pp. 406-412
    • Stalker, T.J.1    Lefer, A.M.2    Scalia, R.3
  • 58
    • 2342536907 scopus 로고    scopus 로고
    • Rosuvastatin reduces MMP-7 secretion by human monocyte-derived macrophages: Potential relevance to atherosclerotic plaque stability
    • Furman C., Copin C., Kandoussi M., et al. Rosuvastatin reduces MMP-7 secretion by human monocyte-derived macrophages: potential relevance to atherosclerotic plaque stability. Atherosclerosis. 2004 ; 174: 93-98.
    • (2004) Atherosclerosis , vol.174 , pp. 93-98
    • Furman, C.1    Copin, C.2    Kandoussi, M.3
  • 59
    • 39249083201 scopus 로고    scopus 로고
    • Effect of rosuvastatin therapy on carotid plaque morphology and composition in moderately hypercholesterolemic patients: A high-resolution magnetic resonance imaging trial
    • Underhill HR, Yuan C., Zhao XQ, et al. Effect of rosuvastatin therapy on carotid plaque morphology and composition in moderately hypercholesterolemic patients: a high-resolution magnetic resonance imaging trial. Am Heart J. 2008 ; 155: 584.e1-e8.
    • (2008) Am Heart J , vol.155
    • Underhill, H.R.1    Yuan, C.2    Zhao, X.Q.3
  • 60
    • 0036790415 scopus 로고    scopus 로고
    • Bone marrow-derived progenitor cells modulate vascular reendothelialization and neointimal formation: Effect of 3-hydroxy-3- methylglutaryl coenzyme a reductase inhibition
    • Werner N PJ, Laufs U., Endres M., Böhm M., Dirnagl U., Nickenig G. Bone marrow-derived progenitor cells modulate vascular reendothelialization and neointimal formation: effect of 3-hydroxy-3-methylglutaryl coenzyme a reductase inhibition. Arterioscler Thromb Vasc Biol. 2002 ; 22: 1567-1572.
    • (2002) Arterioscler Thromb Vasc Biol , vol.22 , pp. 1567-1572
    • Werner, N.P.J.1    Laufs, U.2    Endres, M.3    Böhm, M.4    Dirnagl, U.5    Nickenig, G.6
  • 61
    • 33750931287 scopus 로고    scopus 로고
    • Highly active antiretroviral therapy attenuates re-endothelialization and alters neointima formation in the rat carotid artery after balloon injury
    • Kappert K., Leppanen O., Paulsson J., et al. Highly active antiretroviral therapy attenuates re-endothelialization and alters neointima formation in the rat carotid artery after balloon injury. J Acquir Immune Defic Syndr. 2006 ; 43: 383-392.
    • (2006) J Acquir Immune Defic Syndr , vol.43 , pp. 383-392
    • Kappert, K.1    Leppanen, O.2    Paulsson, J.3
  • 62
    • 23644437626 scopus 로고    scopus 로고
    • Suppression of endothelial progenitor cells in human coronary artery disease by the endogenous nitric oxide synthase inhibitor asymmetric dimethylarginine
    • Thum T., Tsikas D., Stein S., et al. Suppression of endothelial progenitor cells in human coronary artery disease by the endogenous nitric oxide synthase inhibitor asymmetric dimethylarginine. J Am Coll Cardiol. 2005 ; 46: 1693-1701.
    • (2005) J Am Coll Cardiol , vol.46 , pp. 1693-1701
    • Thum, T.1    Tsikas, D.2    Stein, S.3
  • 63
    • 36049013751 scopus 로고    scopus 로고
    • Rosuvastatin regulates vascular smooth muscle cell phenotypic modulation in vascular remodeling: Role for the urokinase receptor
    • Kiyan J., Kusch A., Tkachuk S., et al. Rosuvastatin regulates vascular smooth muscle cell phenotypic modulation in vascular remodeling: role for the urokinase receptor. Atherosclerosis. 2007 ; 195: 254-261.
    • (2007) Atherosclerosis , vol.195 , pp. 254-261
    • Kiyan, J.1    Kusch, A.2    Tkachuk, S.3
  • 64
    • 33847068210 scopus 로고    scopus 로고
    • Different migration of vascular smooth muscle cells from human coronary artery bypass vessels. Role of Rho/ROCK pathway
    • Weiss S., Frischknecht K., Greutert H., et al. Different migration of vascular smooth muscle cells from human coronary artery bypass vessels. Role of Rho/ROCK pathway. J Vasc Res. 2007 ; 44: 149-156.
    • (2007) J Vasc Res , vol.44 , pp. 149-156
    • Weiss, S.1    Frischknecht, K.2    Greutert, H.3
  • 65
    • 12344273558 scopus 로고    scopus 로고
    • Rosuvastatin exerts favourable effects on thrombosis and neointimal growth in a mouse model of endothelial injury
    • Schafer K., Kaiser K., Konstantinides S. Rosuvastatin exerts favourable effects on thrombosis and neointimal growth in a mouse model of endothelial injury. Thromb Haemost. 2005 ; 93: 145-152.
    • (2005) Thromb Haemost , vol.93 , pp. 145-152
    • Schafer, K.1    Kaiser, K.2    Konstantinides, S.3
  • 66
    • 34249697077 scopus 로고    scopus 로고
    • Rosuvastatin restores superoxide dismutase expression and inhibits accumulation of oxidized LDL in the aortic arch of obese dyslipidemic mice
    • Verreth W., De Keyzer D., Davey PC, et al. Rosuvastatin restores superoxide dismutase expression and inhibits accumulation of oxidized LDL in the aortic arch of obese dyslipidemic mice. Br J Pharmacol. 2007 ; 151: 347-355.
    • (2007) Br J Pharmacol , vol.151 , pp. 347-355
    • Verreth, W.1    De Keyzer, D.2    Davey, P.C.3
  • 67
    • 44949097585 scopus 로고    scopus 로고
    • The effect of rosuvastatin treatment on the mean platelet volume in patients with uncontrolled primary dyslipidemia with hypolipidemic diet treatment
    • Coban E Md, Afacan B. The effect of rosuvastatin treatment on the mean platelet volume in patients with uncontrolled primary dyslipidemia with hypolipidemic diet treatment. Platelets. 2007 ; 23: 1-4.
    • (2007) Platelets , vol.23 , pp. 1-4
    • Md, C.E.1    Afacan, B.2
  • 68
    • 33646065014 scopus 로고    scopus 로고
    • Effect of statins on platelet PAR-1 thrombin receptor in patients with the metabolic syndrome (from the PAR-1 inhibition by statins [PARIS] study)
    • Serebruany VL, Miller M., Pokov AN, et al. Effect of statins on platelet PAR-1 thrombin receptor in patients with the metabolic syndrome (from the PAR-1 inhibition by statins [PARIS] study). Am J Cardiol. 2006 ; 97: 1332-1336.
    • (2006) Am J Cardiol , vol.97 , pp. 1332-1336
    • Serebruany, V.L.1    Miller, M.2    Pokov, A.N.3
  • 69
    • 38349163794 scopus 로고    scopus 로고
    • The HMG-CoA reductase inhibitor rosuvastatin inhibits plasminogen activator inhibitor-1 expression and secretion in human adipocytes
    • Laumen H., Skurk T., Hauner H. The HMG-CoA reductase inhibitor rosuvastatin inhibits plasminogen activator inhibitor-1 expression and secretion in human adipocytes. Atherosclerosis. 2008 ; 196: 565-573.
    • (2008) Atherosclerosis , vol.196 , pp. 565-573
    • Laumen, H.1    Skurk, T.2    Hauner, H.3
  • 70
    • 40949136571 scopus 로고    scopus 로고
    • Effect of rosuvastatin on insulin sensitivity in an animal model of insulin resistance: Evidence for statin-induced hepatic insulin sensitization
    • Naples M., Federico LM, Xu E., Nelken J., Adeli K. Effect of rosuvastatin on insulin sensitivity in an animal model of insulin resistance: evidence for statin-induced hepatic insulin sensitization. Atherosclerosis. 2008 ; 198: 94-103.
    • (2008) Atherosclerosis , vol.198 , pp. 94-103
    • Naples, M.1    Federico, L.M.2    Xu, E.3    Nelken, J.4    Adeli, K.5
  • 71
    • 11844249295 scopus 로고    scopus 로고
    • Comparative effects of rosuvastatin and gemfibrozil on glucose, insulin, and lipid metabolism in insulin-resistant, nondiabetic patients with combined dyslipidemia
    • Lamendola C., Abbasi F., Chu JW, et al. Comparative effects of rosuvastatin and gemfibrozil on glucose, insulin, and lipid metabolism in insulin-resistant, nondiabetic patients with combined dyslipidemia. Am J Cardiol. 2005 ; 95: 189-193.
    • (2005) Am J Cardiol , vol.95 , pp. 189-193
    • Lamendola, C.1    Abbasi, F.2    Chu, J.W.3
  • 72
    • 13444272966 scopus 로고    scopus 로고
    • Oral pre-treatment with rosuvastatin protects porcine myocardium from ischaemia/reperfusion injury via a mechanism related to nitric oxide but not to serum cholesterol level
    • Bulhak AA, Gourine AV, Gonon AT, Sjoquist PO, Valen G., Pernow J. Oral pre-treatment with rosuvastatin protects porcine myocardium from ischaemia/reperfusion injury via a mechanism related to nitric oxide but not to serum cholesterol level. Acta Physiol Scand. 2005 ; 183: 151-159.
    • (2005) Acta Physiol Scand , vol.183 , pp. 151-159
    • Aa, B.1    Gourine, A.V.2    Gonon, A.T.3    Sjoquist, P.O.4    Valen, G.5    Pernow, J.6
  • 73
    • 19444368584 scopus 로고    scopus 로고
    • Chronic treatment with rosuvastatin modulates nitric oxide synthase expression and reduces ischemia-reperfusion injury in rat hearts
    • Di Napoli P., Taccardi AA, Grilli A., et al. Chronic treatment with rosuvastatin modulates nitric oxide synthase expression and reduces ischemia-reperfusion injury in rat hearts. Cardiovasc Res. 2005 ; 66: 462-471.
    • (2005) Cardiovasc Res , vol.66 , pp. 462-471
    • Di Napoli, P.1    Aa, T.2    Grilli, A.3
  • 74
    • 15744385725 scopus 로고    scopus 로고
    • Rosuvastatin reduces experimental left ventricular infarct size after ischemia-reperfusion injury but not total coronary occlusion
    • Weinberg EO, Scherrer-Crosbie M., Picard MH, et al. Rosuvastatin reduces experimental left ventricular infarct size after ischemia-reperfusion injury but not total coronary occlusion. Am J Physiol Heart Circ Physiol. 2005 ; 288: H1802 - H1809.
    • (2005) Am J Physiol Heart Circ Physiol , vol.288
    • Weinberg, E.O.1    Scherrer-Crosbie, M.2    Picard, M.H.3
  • 76
    • 0037381031 scopus 로고    scopus 로고
    • Rosuvastatin, a new HMG-CoA reductase inhibitor, protects ischemic reperfused myocardium in normocholesterolemic rats
    • Ikeda Y., Young LH, Lefer AM Rosuvastatin, a new HMG-CoA reductase inhibitor, protects ischemic reperfused myocardium in normocholesterolemic rats. J Cardiovasc Pharmacol. 2003 ; 41: 649-656.
    • (2003) J Cardiovasc Pharmacol , vol.41 , pp. 649-656
    • Ikeda, Y.1    Young, L.H.2    Lefer, A.M.3
  • 77
    • 34447517167 scopus 로고    scopus 로고
    • Cardioprotective effect of rosuvastatin in vivo is dependent on inhibition of geranylgeranyl pyrophosphate and altered RhoA membrane translocation
    • Bulhak A., Roy J., Hedin U., Sjoquist PO, Pernow J. Cardioprotective effect of rosuvastatin in vivo is dependent on inhibition of geranylgeranyl pyrophosphate and altered RhoA membrane translocation. Am J Physiol Heart Circ Physiol. 2007 ; 292: H3158 - H3163.
    • (2007) Am J Physiol Heart Circ Physiol , vol.292
    • Bulhak, A.1    Roy, J.2    Hedin, U.3    Sjoquist, P.O.4    Pernow, J.5
  • 78
    • 33745183117 scopus 로고    scopus 로고
    • Association of RhoGDIalpha with Rac1 GTPase mediates free radical production during myocardial hypertrophy
    • Custodis F., Eberl M., Kilter H., Bohm M., Laufs U. Association of RhoGDIalpha with Rac1 GTPase mediates free radical production during myocardial hypertrophy. Cardiovasc Res. 2006 ; 71: 342-351.
    • (2006) Cardiovasc Res , vol.71 , pp. 342-351
    • Custodis, F.1    Eberl, M.2    Kilter, H.3    Bohm, M.4    Laufs, U.5
  • 79
    • 0035186999 scopus 로고    scopus 로고
    • Statins as antioxidant therapy for preventing cardiac myocyte hypertrophy
    • Takemoto M., Node K., Nakagami H., et al. Statins as antioxidant therapy for preventing cardiac myocyte hypertrophy. J Clin Invest. 2001 ; 108: 1429-1437.
    • (2001) J Clin Invest , vol.108 , pp. 1429-1437
    • Takemoto, M.1    Node, K.2    Nakagami, H.3
  • 80
    • 0141841614 scopus 로고    scopus 로고
    • Oxygen free radical release in human failing myocardium is associated with increased activity of rac1-GTPase and represents a target for statin treatment
    • Maack C., Kartes T., Kilter H., et al. Oxygen free radical release in human failing myocardium is associated with increased activity of rac1-GTPase and represents a target for statin treatment. Circulation. 2003 ; 108: 1567-1574.
    • (2003) Circulation , vol.108 , pp. 1567-1574
    • Maack, C.1    Kartes, T.2    Kilter, H.3
  • 81
    • 0036791698 scopus 로고    scopus 로고
    • Activation of NADPH oxidase during progression of cardiac hypertrophy to failure
    • Li JM, Gall NP, Grieve DJ, Chen M., Shah AM Activation of NADPH oxidase during progression of cardiac hypertrophy to failure. Hypertension. 2002 ; 40: 477-484.
    • (2002) Hypertension , vol.40 , pp. 477-484
    • Li, J.M.1    Gall, N.P.2    Grieve, D.J.3    Chen, M.4    Shah, A.M.5
  • 82
    • 0030611196 scopus 로고    scopus 로고
    • RhoGDIgamma: A GDPdissociation inhibitor for Rho proteins with preferential expression in brain and pancreas
    • Adra CN, Manor D., Ko JL, et al. RhoGDIgamma: a GDPdissociation inhibitor for Rho proteins with preferential expression in brain and pancreas. Proc Natl Acad Sci U S A. 1997 ; 94: 4279-4284.
    • (1997) Proc Natl Acad Sci U S a , vol.94 , pp. 4279-4284
    • Adra, C.N.1    Manor, D.2    Ko, J.L.3
  • 83
    • 34249804809 scopus 로고    scopus 로고
    • Rosuvastatin, a 3-hydroxy-3-methylglutaryl coenzyme a reductase inhibitor, decreases cardiac oxidative stress and remodeling in Ren2 transgenic rats
    • Habibi J., Whaley-Connell A., Qazi MA, et al. Rosuvastatin, a 3-hydroxy-3-methylglutaryl coenzyme a reductase inhibitor, decreases cardiac oxidative stress and remodeling in Ren2 transgenic rats. Endocrinology. 2007 ; 148: 2181-2188.
    • (2007) Endocrinology , vol.148 , pp. 2181-2188
    • Habibi, J.1    Whaley-Connell, A.2    Ma, Q.3
  • 84
    • 39149143680 scopus 로고    scopus 로고
    • Rosuvastatin provides pleiotropic protection against pulmonary hypertension, right ventricular hypertrophy, and coronary endothelial dysfunction in rats
    • Sun X., Ku DD Rosuvastatin provides pleiotropic protection against pulmonary hypertension, right ventricular hypertrophy, and coronary endothelial dysfunction in rats. Am J Physiol Heart Circ Physiol. 2008 ; 294: H801 - H809.
    • (2008) Am J Physiol Heart Circ Physiol , vol.294
    • Sun, X.1    Ku, D.D.2
  • 85
    • 33748174097 scopus 로고    scopus 로고
    • 3-HMG-Coenzyme a reductase inhibition and extracellular matrix gene expression in the pressure-overloaded rat heart
    • Cirrincione GM, Boluyt MO, Hwang HS, Bleske BE 3-HMG-Coenzyme A reductase inhibition and extracellular matrix gene expression in the pressure-overloaded rat heart. J Cardiovasc Pharmacol. 2006 ; 47: 521-530.
    • (2006) J Cardiovasc Pharmacol , vol.47 , pp. 521-530
    • Cirrincione, G.M.1    Boluyt, M.O.2    Hwang, H.S.3    Bleske, B.E.4
  • 86
    • 33847309058 scopus 로고    scopus 로고
    • Double-blind, randomized, placebo-controlled study of high-dose HMG CoA reductase inhibitor therapy on ventricular remodeling, pro-inflammatory cytokines and neurohormonal parameters in patients with chronic systolic heart failure
    • Krum H., Ashton E., Reid C., et al. Double-blind, randomized, placebo-controlled study of high-dose HMG CoA reductase inhibitor therapy on ventricular remodeling, pro-inflammatory cytokines and neurohormonal parameters in patients with chronic systolic heart failure. J Card Fail. 2007 ; 13: 1-7.
    • (2007) J Card Fail , vol.13 , pp. 1-7
    • Krum, H.1    Ashton, E.2    Reid, C.3
  • 87
    • 0038179586 scopus 로고    scopus 로고
    • Rosuvastatin decreases caveolin-1 and improves nitric oxide-dependent heart rate and blood pressure variability in apolipoprotein E-/- mice in vivo
    • Pelat M., Dessy C., Massion P., Desager JP, Feron O., Balligand JL Rosuvastatin decreases caveolin-1 and improves nitric oxide-dependent heart rate and blood pressure variability in apolipoprotein E-/- mice in vivo. Circulation. 2003 ; 107: 2480-2486.
    • (2003) Circulation , vol.107 , pp. 2480-2486
    • Pelat, M.1    Dessy, C.2    Massion, P.3    Desager, J.P.4    Feron, O.5    Balligand, J.L.6
  • 88
    • 0036179620 scopus 로고    scopus 로고
    • Blood pressure variability and organ damage in a general population: Results from the PAMELA study (Pressioni Arteriose Monitorate e Loro Associazioni)
    • Sega R., Corrao G., Bombelli M., et al. Blood pressure variability and organ damage in a general population: results from the PAMELA study (Pressioni Arteriose Monitorate E Loro Associazioni). Hypertension. 2002 ; 39: 710-714.
    • (2002) Hypertension , vol.39 , pp. 710-714
    • Sega, R.1    Corrao, G.2    Bombelli, M.3
  • 89
    • 0034362239 scopus 로고    scopus 로고
    • Role of nitric oxide in buffering short-term blood pressure fluctuations
    • Stauss HM, Persson PB Role of nitric oxide in buffering short-term blood pressure fluctuations. News Physiol Sci. 2000 ; 15: 229-233.
    • (2000) News Physiol Sci , vol.15 , pp. 229-233
    • Stauss, H.M.1    Persson, P.B.2
  • 90
    • 39449126531 scopus 로고    scopus 로고
    • Early impairment of left ventricular function in hypercholesterolemia and its reversibility after short term treatment with rosuvastatin. a preliminary echocardiographic study
    • Talini E., DiBello V., Bianchi C., et al. Early impairment of left ventricular function in hypercholesterolemia and its reversibility after short term treatment with rosuvastatin. A preliminary echocardiographic study. Atherosclerosis. 2008 ; 197: 346-354.
    • (2008) Atherosclerosis , vol.197 , pp. 346-354
    • Talini, E.1    Dibello, V.2    Bianchi, C.3
  • 91
    • 36549030340 scopus 로고    scopus 로고
    • CORONA Group. Rosuvastatin in older patients with systolic heart failure
    • Kjekshus J., Apetrei E., Barrios V.,, et al. CORONA Group. Rosuvastatin in older patients with systolic heart failure. N Engl J Med. 2007 ; 357: 2248-2261.
    • (2007) N Engl J Med , vol.357 , pp. 2248-2261
    • Kjekshus, J.1    Apetrei, E.2    Barrios, V.3
  • 92
    • 0037189048 scopus 로고    scopus 로고
    • Rosuvastatin, a new HMG-CoA reductase inhibitor, upregulates endothelial nitric oxide synthase and protects from ischemic stroke in mice
    • Laufs U., Gertz K., Dirnagl U., Bohm M., Nickenig G., Endres M. Rosuvastatin, a new HMG-CoA reductase inhibitor, upregulates endothelial nitric oxide synthase and protects from ischemic stroke in mice. Brain Res. 2002 ; 942: 23-30.
    • (2002) Brain Res , vol.942 , pp. 23-30
    • Laufs, U.1    Gertz, K.2    Dirnagl, U.3    Bohm, M.4    Nickenig, G.5    Endres, M.6
  • 93
    • 41749088284 scopus 로고    scopus 로고
    • The protective effect of rosuvastatin on ischemic brain injury and its mechanism
    • Xing H., Sun S., Mei Y., Herman D. The protective effect of rosuvastatin on ischemic brain injury and its mechanism. J Huazhong Univ Sci Technolog Med Sci. 2006 ; 26: 667-669.
    • (2006) J Huazhong Univ Sci Technolog Med Sci , vol.26 , pp. 667-669
    • Xing, H.1    Sun, S.2    Mei, Y.3    Herman, D.4
  • 94
    • 33747784874 scopus 로고    scopus 로고
    • Reduction of cerebral infarct size by the AT1-receptor blocker candesartan, the HMG-CoA reductase inhibitor rosuvastatin and their combination. An experimental study in rats
    • Engelhorn T., Doerfler A., Heusch G., Schulz R. Reduction of cerebral infarct size by the AT1-receptor blocker candesartan, the HMG-CoA reductase inhibitor rosuvastatin and their combination. An experimental study in rats. Neurosci Lett. 2006 ; 406: 92-96.
    • (2006) Neurosci Lett , vol.406 , pp. 92-96
    • Engelhorn, T.1    Doerfler, A.2    Heusch, G.3    Schulz, R.4
  • 95
    • 39349090619 scopus 로고    scopus 로고
    • Intravenous rosuvastatin for acute stroke treatment: An animal study
    • Prinz V., Laufs U., Gertz K., et al. Intravenous rosuvastatin for acute stroke treatment: an animal study. Stroke. 2008 ; 39: 433-438.
    • (2008) Stroke , vol.39 , pp. 433-438
    • Prinz, V.1    Laufs, U.2    Gertz, K.3
  • 96
    • 23644460358 scopus 로고    scopus 로고
    • Post-ischemic delivery of the 3-hydroxy-3-methylglutaryl coenzyme a reductase inhibitor rosuvastatin protects against focal cerebral ischemia in mice via inhibition of extracellular-regulated kinase-1/-2
    • Kilic U., Bassetti CL, Kilic E., Xing H., Wang Z., Hermann DM Post-ischemic delivery of the 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor rosuvastatin protects against focal cerebral ischemia in mice via inhibition of extracellular-regulated kinase-1/-2. Neuroscience. 2005 ; 134: 901-906.
    • (2005) Neuroscience , vol.134 , pp. 901-906
    • Kilic, U.1    Bassetti, C.L.2    Kilic, E.3    Xing, H.4    Wang, Z.5    Hermann, D.M.6
  • 97
    • 12844276482 scopus 로고    scopus 로고
    • Aggravation of focal cerebral ischemia by tissue plasminogen activator is reversed by 3-hydroxy-3-methylglutaryl coenzyme a reductase inhibitor but does not depend on endothelial NO synthase
    • Kilic E., Kilic U., Matter CM, Luscher TF, Bassetti CL, Hermann DM Aggravation of focal cerebral ischemia by tissue plasminogen activator is reversed by 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor but does not depend on endothelial NO synthase. Stroke. 2005 ; 36: 332-336.
    • (2005) Stroke , vol.36 , pp. 332-336
    • Kilic, E.1    Kilic, U.2    Matter, C.M.3    Luscher, T.F.4    Bassetti, C.L.5    Hermann, D.M.6
  • 98
    • 0346749450 scopus 로고    scopus 로고
    • 3-hydroxy-3-methylglutaryl coenzyme a reductase inhibitors protect cortical neurons from excitotoxicity
    • Zacco A., Togo J., Spence K., et al. 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors protect cortical neurons from excitotoxicity. J Neurosci. 2003 ; 23: 11104-11111.
    • (2003) J Neurosci , vol.23 , pp. 11104-11111
    • Zacco, A.1    Togo, J.2    Spence, K.3
  • 99
    • 33645732870 scopus 로고    scopus 로고
    • Rosuvastatin improves cerebrovascular function in Zucker obese rats by inhibiting NAD(P)H oxidase-dependent superoxide production
    • Erdos B., Snipes JA, Tulbert CD, Katakam P., Miller AW, Busija DW Rosuvastatin improves cerebrovascular function in Zucker obese rats by inhibiting NAD(P)H oxidase-dependent superoxide production. Am J Physiol Heart Circ Physiol. 2006 ; 290: H1264 - H1270.
    • (2006) Am J Physiol Heart Circ Physiol , vol.290
    • Erdos, B.1    Snipes, J.A.2    Tulbert, C.D.3    Katakam, P.4    Miller, A.W.5    Busija, D.W.6
  • 101
    • 14644432487 scopus 로고    scopus 로고
    • Rosuvastatin, but not simvastatin, provides end-organ protection in stroke-prone rats by antiinflammatory effects
    • Sironi L., Gianazza E., Gelosa P., et al. Rosuvastatin, but not simvastatin, provides end-organ protection in stroke-prone rats by antiinflammatory effects. Arterioscler Thromb Vasc Biol. 2005 ; 25: 598-603.
    • (2005) Arterioscler Thromb Vasc Biol , vol.25 , pp. 598-603
    • Sironi, L.1    Gianazza, E.2    Gelosa, P.3
  • 102
    • 7444229915 scopus 로고    scopus 로고
    • Rosuvastatin reduces caspase-3 activity and up-regulates alpha-secretase in human neuroblastoma SH-SY5Y cells exposed to a beta
    • Famer D., Crisby M. Rosuvastatin reduces caspase-3 activity and up-regulates alpha-secretase in human neuroblastoma SH-SY5Y cells exposed to A beta. Neurosci Lett. 2004 ; 371: 209-214.
    • (2004) Neurosci Lett , vol.371 , pp. 209-214
    • Famer, D.1    Crisby, M.2
  • 103
    • 0042837889 scopus 로고    scopus 로고
    • Caspase activation in the limbic cortex of subjects with early Alzheimer's disease
    • Gastard MC, Troncoso JC, Koliatsos VE Caspase activation in the limbic cortex of subjects with early Alzheimer's disease. Ann Neurol. 2003 ; 54: 393-398.
    • (2003) Ann Neurol , vol.54 , pp. 393-398
    • Gastard, M.C.1    Troncoso, J.C.2    Koliatsos, V.E.3
  • 104
    • 0035066332 scopus 로고    scopus 로고
    • Alzheimer's disease: Genes, proteins, and therapy
    • Selkoe DJ Alzheimer's disease: genes, proteins, and therapy. Physiol Rev. 2001 ; 81: 741-766.
    • (2001) Physiol Rev , vol.81 , pp. 741-766
    • Selkoe, D.J.1
  • 105
    • 0037110424 scopus 로고    scopus 로고
    • The role of macrophage/microglia and astrocytes in the pathogenesis of three neurologic disorders: HIV-associated dementia, Alzheimer disease, and multiple sclerosis
    • Minagar A., Shapshak P., Fujimura R., Ownby R., Heyes M., Eisdorfer C. The role of macrophage/microglia and astrocytes in the pathogenesis of three neurologic disorders: HIV-associated dementia, Alzheimer disease, and multiple sclerosis. J Neurol Sci. 2002 ; 202: 13-23.
    • (2002) J Neurol Sci , vol.202 , pp. 13-23
    • Minagar, A.1    Shapshak, P.2    Fujimura, R.3    Ownby, R.4    Heyes, M.5    Eisdorfer, C.6
  • 106
    • 34247891579 scopus 로고    scopus 로고
    • Rosuvastatin reduces gliosis and the accelerated weight gain observed in WT and ApoE-/mice exposed to a high cholesterol diet
    • Famer D., Crisby M. Rosuvastatin reduces gliosis and the accelerated weight gain observed in WT and ApoE-/mice exposed to a high cholesterol diet. Neurosci Lett. 2007 ; 419: 68-73.
    • (2007) Neurosci Lett , vol.419 , pp. 68-73
    • Famer, D.1    Crisby, M.2
  • 107
    • 34248208657 scopus 로고    scopus 로고
    • Effects of statins on alpha7 nicotinic receptor, cholinesterase and alpha-form of secreted amyloid precursor peptide in SH-SY5Y cells
    • Roensch J., Crisby M., Nordberg A., Xiao Y., Zhang LJ, Guan ZZ Effects of statins on alpha7 nicotinic receptor, cholinesterase and alpha-form of secreted amyloid precursor peptide in SH-SY5Y cells. Neurochem Int. 2007 ; 50: 800-806.
    • (2007) Neurochem Int , vol.50 , pp. 800-806
    • Roensch, J.1    Crisby, M.2    Nordberg, A.3    Xiao, Y.4    Zhang, L.J.5    Guan, Z.Z.6
  • 108
    • 21844474541 scopus 로고    scopus 로고
    • Neuronal nitric oxide synthase mediates statin-induced restoration of vasa nervorum and reversal of diabetic neuropathy
    • Ii M., Nishimura H., Kusano KF, et al. Neuronal nitric oxide synthase mediates statin-induced restoration of vasa nervorum and reversal of diabetic neuropathy. Circulation. 2005 ; 112: 93-102.
    • (2005) Circulation , vol.112 , pp. 93-102
    • Ii, M.1    Nishimura, H.2    Kusano, K.F.3
  • 110
    • 37349043715 scopus 로고    scopus 로고
    • Vascular and neural dysfunction in Zucker diabetic fatty rats: A difficult condition to reverse
    • Oltman CL, Davidson EP, Coppey LJ, et al. Vascular and neural dysfunction in Zucker diabetic fatty rats: a difficult condition to reverse. Diabetes Obes Metab. 2008 ; 10: 64-74.
    • (2008) Diabetes Obes Metab , vol.10 , pp. 64-74
    • Oltman, C.L.1    Davidson, E.P.2    Coppey, L.J.3
  • 111
    • 33646701223 scopus 로고    scopus 로고
    • Effect of short-term rosuvastatin treatment on estimated glomerular filtration rate
    • Vidt DG, Harris S., McTaggart F., Ditmarsch M., Sager PT, Sorof JM Effect of short-term rosuvastatin treatment on estimated glomerular filtration rate. Am J Cardiol. 2006 ; 97: 1602-1606.
    • (2006) Am J Cardiol , vol.97 , pp. 1602-1606
    • Vidt, D.G.1    Harris, S.2    McTaggart, F.3    Ditmarsch, M.4    Sager, P.T.5    Sorof, J.M.6
  • 113
    • 27144534466 scopus 로고    scopus 로고
    • Effect of rosuvastatin on C-reactive protein and renal function in patients with chronic kidney disease
    • Verma A., Ranganna KM, Reddy RS, Verma M., Gordon NF Effect of rosuvastatin on C-reactive protein and renal function in patients with chronic kidney disease. Am J Cardiol. 2005 ; 96: 1290-1292.
    • (2005) Am J Cardiol , vol.96 , pp. 1290-1292
    • Verma, A.1    Ranganna, K.M.2    Reddy, R.S.3    Verma, M.4    Gordon, N.F.5
  • 114
    • 33645288571 scopus 로고    scopus 로고
    • Effect of rosuvastatin or atorvastatin on urinary albumin excretion and renal function in type 2 diabetic patients
    • Sorof J., Berne C., Siewert-Delle A., Jorgensen L., Sager P. Effect of rosuvastatin or atorvastatin on urinary albumin excretion and renal function in type 2 diabetic patients. Diabetes Res Clin Pract. 2006 ; 72: 81-87.
    • (2006) Diabetes Res Clin Pract , vol.72 , pp. 81-87
    • Sorof, J.1    Berne, C.2    Siewert-Delle, A.3    Jorgensen, L.4    Sager, P.5
  • 115
    • 33749866051 scopus 로고    scopus 로고
    • Rosuvastatin increases alpha-1 microglobulin urinary excretion in patients with primary dyslipidemia
    • Kostapanos MS, Milionis HJ, Gazi I., Kostara C., Bairaktari ET, Elisaf M. Rosuvastatin increases alpha-1 microglobulin urinary excretion in patients with primary dyslipidemia. J Clin Pharmacol. 2006 ; 46: 1337-1343.
    • (2006) J Clin Pharmacol , vol.46 , pp. 1337-1343
    • Kostapanos, M.S.1    Milionis, H.J.2    Gazi, I.3    Kostara, C.4    Bairaktari, E.T.5    Elisaf, M.6
  • 116
    • 37249013533 scopus 로고    scopus 로고
    • Dose-dependent effect of rosuvastatin treatment on urinary protein excretion
    • Kostapanos MS, Milionis HJ, Saougos VG, et al. Dose-dependent effect of rosuvastatin treatment on urinary protein excretion. J Cardiovasc Pharmacol Ther. 2007 ; 12: 292-297.
    • (2007) J Cardiovasc Pharmacol Ther , vol.12 , pp. 292-297
    • Kostapanos, M.S.1    Milionis, H.J.2    Saougos, V.G.3
  • 117
    • 34247893910 scopus 로고    scopus 로고
    • Rosuvastatin treatment prevents progressive kidney inflammation and fibrosis in stroke-prone rats
    • Gianella A., Nobili E., Abbate M., et al. Rosuvastatin treatment prevents progressive kidney inflammation and fibrosis in stroke-prone rats. Am J Pathol. 2007 ; 170: 1165-1177.
    • (2007) Am J Pathol , vol.170 , pp. 1165-1177
    • Gianella, A.1    Nobili, E.2    Abbate, M.3
  • 118
    • 36249017958 scopus 로고    scopus 로고
    • Insulin resistance, oxidative stress, and podocyte injury: Role of rosuvastatin modulation of filtration barrier injury
    • Whaley-Connell A., DeMarco VG, Lastra G., et al. Insulin resistance, oxidative stress, and podocyte injury: role of rosuvastatin modulation of filtration barrier injury. Am J Nephrol. 2008 ; 28: 67-75.
    • (2008) Am J Nephrol , vol.28 , pp. 67-75
    • Whaley-Connell, A.1    Demarco, V.G.2    Lastra, G.3
  • 119
    • 38549135458 scopus 로고    scopus 로고
    • Attenuation of NADPH oxidase activation and glomerular filtration barrier remodeling with statin treatment
    • Whaley-Connell A., Habibi J., Nistala R., et al. Attenuation of NADPH oxidase activation and glomerular filtration barrier remodeling with statin treatment. Hypertension. 2008 ; 51: 474-480.
    • (2008) Hypertension , vol.51 , pp. 474-480
    • Whaley-Connell, A.1    Habibi, J.2    Nistala, R.3
  • 120
    • 44949135069 scopus 로고    scopus 로고
    • Rosuvastatin is additive to high-dose candesartan in slowing progression of experimental mesangioproliferative glomerulosclerosis
    • Krämer S., Kron S., Wang-Rosenke Y., et al. Rosuvastatin is additive to high-dose candesartan in slowing progression of experimental mesangioproliferative glomerulosclerosis. Am J Physiol Renal Physiol. 2008 ; 294: F801 - F811.
    • (2008) Am J Physiol Renal Physiol , vol.294
    • Krämer, S.1    Kron, S.2    Wang-Rosenke, Y.3
  • 121
    • 33847618799 scopus 로고    scopus 로고
    • Albumin activation of NAD(P)H oxidase activity is mediated via Rac1 in proximal tubule cells
    • Whaley-Connell AT, Morris EM, Rehmer N., et al. Albumin activation of NAD(P)H oxidase activity is mediated via Rac1 in proximal tubule cells. Am J Nephrol. 2007 ; 27: 15-23.
    • (2007) Am J Nephrol , vol.27 , pp. 15-23
    • Whaley-Connell, A.T.1    Morris, E.M.2    Rehmer, N.3
  • 122
    • 38349120435 scopus 로고    scopus 로고
    • Rosuvastatin improves basal nitric oxide activity of the renal vasculature in patients with hypercholesterolemia
    • Ott C., Schlaich MP, Schmidt BM, Titze SI, Schaufele T., Schmieder RE Rosuvastatin improves basal nitric oxide activity of the renal vasculature in patients with hypercholesterolemia. Atherosclerosis. 2007 ; 196: 704-711.
    • (2007) Atherosclerosis , vol.196 , pp. 704-711
    • Ott, C.1    Schlaich, M.P.2    Schmidt, B.M.3    Titze, S.I.4    Schaufele, T.5    Schmieder, R.E.6
  • 123
    • 33646095764 scopus 로고    scopus 로고
    • An overview of statin-associated proteinuria
    • Tiwari A. An overview of statin-associated proteinuria. Drug Discov Today. 2006 ; 11: 458-464.
    • (2006) Drug Discov Today , vol.11 , pp. 458-464
    • Tiwari, A.1
  • 124
    • 35549004107 scopus 로고    scopus 로고
    • Effects of rosuvastatin on glomerular capillary size-selectivity function in rats with renal mass ablation
    • Corna D SF, Cattaneo D., Carrara F., et al. Effects of rosuvastatin on glomerular capillary size-selectivity function in rats with renal mass ablation. Am J Nephrol. 2007 ; 27: 630-638.
    • (2007) Am J Nephrol , vol.27 , pp. 630-638
    • Corna, D.S.F.1    Cattaneo, D.2    Carrara, F.3
  • 125
    • 4344667844 scopus 로고    scopus 로고
    • Inhibitors of 3-hydroxy-3-methylglutaryl-CoA reductase reduce receptor-mediated endocytosis in opossum kidney cells
    • Sidaway JE, Davidson RG, McTaggart F., et al. Inhibitors of 3-hydroxy-3-methylglutaryl-CoA reductase reduce receptor-mediated endocytosis in opossum kidney cells. J Am Soc Nephrol. 2004 ; 15: 2258-2265.
    • (2004) J Am Soc Nephrol , vol.15 , pp. 2258-2265
    • Sidaway, J.E.1    Davidson, R.G.2    McTaggart, F.3
  • 126
    • 4344566156 scopus 로고    scopus 로고
    • Inhibitors of HMG-CoA reductase reduce receptor-mediated endocytosis in human kidney proximal tubular cells
    • Verhulst A., D'Haese PC, De Broe ME Inhibitors of HMG-CoA reductase reduce receptor-mediated endocytosis in human kidney proximal tubular cells. J Am Soc Nephrol. 2004 ; 15: 2249-2257.
    • (2004) J Am Soc Nephrol , vol.15 , pp. 2249-2257
    • Verhulst, A.1    D'Haese, P.C.2    De Broe, M.E.3
  • 127
    • 33745727522 scopus 로고    scopus 로고
    • Rosuvastatin, a new HMG-CoA reductase inhibitor, reduces the colonic inflammatory response in dextran sulfate sodium-induced colitis in mice
    • Naito Y., Katada K., Takagi T., et al. Rosuvastatin, a new HMG-CoA reductase inhibitor, reduces the colonic inflammatory response in dextran sulfate sodium-induced colitis in mice. Int J Mol Med. 2006 ; 17: 997-1004.
    • (2006) Int J Mol Med , vol.17 , pp. 997-1004
    • Naito, Y.1    Katada, K.2    Takagi, T.3
  • 128
    • 33646465740 scopus 로고    scopus 로고
    • Rosuvastatin reduces rat intestinal ischemia-reperfusion injury associated with the preservation of endothelial nitric oxide synthase protein
    • Naito Y., Katada K., Takagi T., et al. Rosuvastatin reduces rat intestinal ischemia-reperfusion injury associated with the preservation of endothelial nitric oxide synthase protein. World J Gastroenterol. 2006 ; 12: 2024-2030.
    • (2006) World J Gastroenterol , vol.12 , pp. 2024-2030
    • Naito, Y.1    Katada, K.2    Takagi, T.3
  • 129
    • 28344436469 scopus 로고    scopus 로고
    • Rosuvastatin as a novel treatment of non-alcoholic fatty liver disease in hyperlipidemic patients
    • Antonopoulos S., Mikros S., Mylonopoulou M., Kokkoris S., Giannoulis G. Rosuvastatin as a novel treatment of non-alcoholic fatty liver disease in hyperlipidemic patients. Atherosclerosis. 2006 ; 184: 233-234.
    • (2006) Atherosclerosis , vol.184 , pp. 233-234
    • Antonopoulos, S.1    Mikros, S.2    Mylonopoulou, M.3    Kokkoris, S.4    Giannoulis, G.5
  • 130
    • 25444500664 scopus 로고    scopus 로고
    • Rosuvastatin: A risk-benefit assessment for intensive lipid lowering
    • Ferdinand KC Rosuvastatin: a risk-benefit assessment for intensive lipid lowering. Expert Opin Pharmacother. 2005 ; 6: 1897-1910.
    • (2005) Expert Opin Pharmacother , vol.6 , pp. 1897-1910
    • Ferdinand, K.C.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.