-
1
-
-
26444578943
-
The statin studies: From targeting hypercholesterolaemia to targeting the high-risk patient
-
Ong HT The statin studies: from targeting hypercholesterolaemia to targeting the high-risk patient. QJM. 2005 ; 98: 599-614.
-
(2005)
QJM
, vol.98
, pp. 599-614
-
-
Ong, H.T.1
-
2
-
-
0037420492
-
For the ASCOT Investigators. Prevention of coronary and stroke events with atorvastatin in hypertensive patients who have average or lower-than-average cholesterol concentrations, in the Anglo-Scandinavian Cardiac Outcomes Trial-Lipid Lowering Arm (ASCOT-LLA): A multicentre randomized controlled trial
-
Sever PS DB, Poulter NR, Wedel H., et al, for the ASCOT Investigators. Prevention of coronary and stroke events with atorvastatin in hypertensive patients who have average or lower-than-average cholesterol concentrations, in the Anglo-Scandinavian Cardiac Outcomes Trial-Lipid Lowering Arm (ASCOT-LLA): a multicentre randomized controlled trial. Lancet. 2003 ; 361: 1149-1158.
-
(2003)
Lancet
, vol.361
, pp. 1149-1158
-
-
Sever, P.S.D.B.1
Poulter, N.R.2
Wedel, H.3
-
3
-
-
15944410609
-
For the Treating to New Targets (TNT) Investigators. Intensive lipid lowering with atorvastatin in patients with stable coronary disease
-
LaRosa JC, Grundy SM, Waters DD, et al, for the Treating to New Targets (TNT) Investigators. Intensive lipid lowering with atorvastatin in patients with stable coronary disease. N Engl J Med. 2005 ; 352: 1-11.
-
(2005)
N Engl J Med
, vol.352
, pp. 1-11
-
-
Larosa, J.C.1
Grundy, S.M.2
Waters, D.D.3
-
4
-
-
26244432388
-
Efficacy and safety of cholesterol-lowering treatment: Prospective meta-analysis of data from 90,056 participants in 14 randomised trials of statins
-
Baigent C., Keech A., Kearney PM, et al. Efficacy and safety of cholesterol-lowering treatment: prospective meta-analysis of data from 90,056 participants in 14 randomised trials of statins. Lancet. 2005 ; 366: 1267-1278.
-
(2005)
Lancet
, vol.366
, pp. 1267-1278
-
-
Baigent, C.1
Keech, A.2
Kearney, P.M.3
-
5
-
-
33646829645
-
Efficacy of lipid lowering drug treatment for diabetic and nondiabetic patients: Meta-analysis of randomised controlled trials
-
Costa J., Borges M., David C., Vaz Carneiro A. Efficacy of lipid lowering drug treatment for diabetic and nondiabetic patients: meta-analysis of randomised controlled trials. BMJ. 2006 ; 332: 1115-1124.
-
(2006)
BMJ
, vol.332
, pp. 1115-1124
-
-
Costa, J.1
Borges, M.2
David, C.3
Vaz Carneiro, A.4
-
6
-
-
0032554676
-
Influence of pravastatin and plasma lipids on clinical events in the West of Scotland Coronary Prevention Study (WOSCOPS)
-
WOSCOPS Study Group. Influence of pravastatin and plasma lipids on clinical events in the West of Scotland Coronary Prevention Study (WOSCOPS). Circulation. 1998 ; 97: 1440-1445.
-
(1998)
Circulation
, vol.97
, pp. 1440-1445
-
-
Study Group, W.1
-
7
-
-
23944445364
-
Effects of statins on 3-hydroxy-3-methylglutaryl coenzyme a reductase inhibition beyond low-density lipoprotein cholesterol
-
Liao JK Effects of statins on 3-hydroxy-3-methylglutaryl coenzyme a reductase inhibition beyond low-density lipoprotein cholesterol. Am J Cardiol. 2005 ; 96: 24F - 33F.
-
(2005)
Am J Cardiol
, vol.96
-
-
Liao, J.K.1
-
8
-
-
34249895036
-
Do statins have an antiarrhythmic activity
-
Kostapanos MS, Liberopoulos EN, Goudevenos JA, Mikhailidis DP, Elisaf MS Do statins have an antiarrhythmic activity ? Cardiovasc Res. 2007 ; 75: 10-20.
-
(2007)
Cardiovasc Res
, vol.75
, pp. 10-20
-
-
Kostapanos, M.S.1
Liberopoulos, E.N.2
Goudevenos, J.A.3
Mikhailidis, D.P.4
Elisaf, M.S.5
-
9
-
-
16344389130
-
A review of the lipid-related effects of fluvastatin
-
Liberopoulos EN, Daskalopoulou SS, Mikhailidis DP, Wierzbicki AS, Elisaf MS A review of the lipid-related effects of fluvastatin. Curr Med Res Opin. 2005 ; 21: 231-244.
-
(2005)
Curr Med Res Opin
, vol.21
, pp. 231-244
-
-
Liberopoulos, E.N.1
Daskalopoulou, S.S.2
Mikhailidis, D.P.3
Wierzbicki, A.S.4
Elisaf, M.S.5
-
10
-
-
33751180331
-
Beyond lipid lowering: What have we learned about the benefits of statins from the acute coronary syndromes trials?
-
Ray KK, Cannon CP, Ganz P. Beyond lipid lowering: What have we learned about the benefits of statins from the acute coronary syndromes trials? Am J Cardiol. 2006 ; 98: 18P - 25P.
-
(2006)
Am J Cardiol
, vol.98
-
-
Ray, K.K.1
Cannon, C.P.2
Ganz, P.3
-
11
-
-
0038645309
-
Comparison of the efficacy and safety of rosuvastatin versus atorvastatin, simvastatin, and pravastatin across doses (STELLAR* Trial)
-
Jones PH, Davidson MH, Stein EA, et al. Comparison of the efficacy and safety of rosuvastatin versus atorvastatin, simvastatin, and pravastatin across doses (STELLAR* Trial). Am J Cardiol. 2003 ; 92: 152-160.
-
(2003)
Am J Cardiol
, vol.92
, pp. 152-160
-
-
Ph, J.1
Davidson, M.H.2
Stein, E.A.3
-
12
-
-
11844302289
-
Twelve-week, multicenter, randomized, open-label comparison of the effects of rosuvastatin 10 mg/d and atorvastatin 10 mg/d in high-risk adults: A DISCOVERY study
-
Strandberg TE, Feely J., Sigurdsson EL Twelve-week, multicenter, randomized, open-label comparison of the effects of rosuvastatin 10 mg/d and atorvastatin 10 mg/d in high-risk adults: a DISCOVERY study. Clin Ther. 2004 ; 26: 1821-1833.
-
(2004)
Clin Ther
, vol.26
, pp. 1821-1833
-
-
Strandberg, T.E.1
Feely, J.2
El, S.3
-
13
-
-
33845987739
-
Expanding options with a wider range of rosuvastatin doses
-
Olsson A. Expanding options with a wider range of rosuvastatin doses. Clin Ther. 2006 ; 28: 1747-1763.
-
(2006)
Clin Ther
, vol.28
, pp. 1747-1763
-
-
Olsson, A.1
-
14
-
-
33947651074
-
The GALAXY Program: An update on studies investigating efficacy and tolerability of rosuvastatin for reducing cardiovascular risk
-
Schuster H. The GALAXY Program: an update on studies investigating efficacy and tolerability of rosuvastatin for reducing cardiovascular risk. Expert Rev Cardiovasc Ther. 2007 ; 5: 177-193.
-
(2007)
Expert Rev Cardiovasc Ther
, vol.5
, pp. 177-193
-
-
Schuster, H.1
-
15
-
-
0141560665
-
Comparative pharmacology of rosuvastatin
-
McTaggart F. Comparative pharmacology of rosuvastatin. Atheroscler Suppl. 2003 ; 4: 9-14.
-
(2003)
Atheroscler Suppl
, vol.4
, pp. 9-14
-
-
McTaggart, F.1
-
16
-
-
33947713026
-
Effect of rosuvastatin on progression of carotid intima-media thickness in low-risk individuals with subclinical atherosclerosis: The METEOR Trial
-
Crouse JR 3rd, Raichlen JS, Riley WA, et al. Effect of rosuvastatin on progression of carotid intima-media thickness in low-risk individuals with subclinical atherosclerosis: the METEOR Trial. JAMA. 2007 ; 297: 1344-1353.
-
(2007)
JAMA
, vol.297
, pp. 1344-1353
-
-
Crouse III, J.R.1
Raichlen, J.S.2
Riley, W.A.3
-
17
-
-
33645524176
-
Effect of very high-intensity statin therapy on regression of coronary atherosclerosis: The ASTEROID trial
-
Nissen SE, Nicholls SJ, Sipahi I., et al. Effect of very high-intensity statin therapy on regression of coronary atherosclerosis: the ASTEROID trial. JAMA. 2006 ; 295: 1556-1565.
-
(2006)
JAMA
, vol.295
, pp. 1556-1565
-
-
Nissen, S.E.1
Nicholls, S.J.2
Sipahi, I.3
-
18
-
-
18244362843
-
Rosuvastatin reduces platelet activation in heart failure: Role of NO bioavailability
-
Schafer A., Fraccarollo D., Eigenthaler M., et al. Rosuvastatin reduces platelet activation in heart failure: role of NO bioavailability. Arterioscler Thromb Vasc Biol. 2005 ; 25: 1071-1077.
-
(2005)
Arterioscler Thromb Vasc Biol
, vol.25
, pp. 1071-1077
-
-
Schafer, A.1
Fraccarollo, D.2
Eigenthaler, M.3
-
19
-
-
25444501302
-
Effects of rosuvastatin on endothelial function in patients with familial combined hyperlipidaemia (FCH)
-
ter Avest E., Abbink EJ, Holewijn S., de Graaf J., Tack CJ, Stalenhoef AF Effects of rosuvastatin on endothelial function in patients with familial combined hyperlipidaemia (FCH). Curr Med Res Opin. 2005 ; 21: 1469-1476.
-
(2005)
Curr Med Res Opin
, vol.21
, pp. 1469-1476
-
-
Ter Avest, E.1
Abbink, E.J.2
Holewijn, S.3
De Graaf, J.4
Tack, C.J.5
Stalenhoef, A.F.6
-
20
-
-
0041820000
-
Effects of rosuvastatin on nitric oxide-dependent function in aorta and corpus cavernosum of diabetic mice: Relationship to cholesterol biosynthesis pathway inhibition and lipid lowering
-
Nangle MR, Cotter MA, Cameron NE Effects of rosuvastatin on nitric oxide-dependent function in aorta and corpus cavernosum of diabetic mice: relationship to cholesterol biosynthesis pathway inhibition and lipid lowering. Diabetes. 2003 ; 52: 2396-2402.
-
(2003)
Diabetes
, vol.52
, pp. 2396-2402
-
-
Nangle, M.R.1
Ma, C.2
Cameron, N.E.3
-
21
-
-
3042738127
-
Rosuvastatin treatment reverses impaired coronary artery vasodilation in fructose-fed, insulin-resistant rats
-
Miller AW, Tulbert CD, Busija DW Rosuvastatin treatment reverses impaired coronary artery vasodilation in fructose-fed, insulin-resistant rats. Am J Physiol Regul Integr Comp Physiol. 2004 ; 287: R157 - R160.
-
(2004)
Am J Physiol Regul Integr Comp Physiol
, vol.287
-
-
Miller, A.W.1
Tulbert, C.D.2
Busija, D.W.3
-
22
-
-
33947378811
-
Improved endothelial function and reduced platelet activation by chronic HMG-CoA-reductase inhibition with rosuvastatin in rats with streptozotocin- induced diabetes mellitus
-
Schafer A., Fraccarollo D., Vogt C., et al. Improved endothelial function and reduced platelet activation by chronic HMG-CoA-reductase inhibition with rosuvastatin in rats with streptozotocin-induced diabetes mellitus. Biochem Pharmacol. 2007 ; 73: 1367-1375.
-
(2007)
Biochem Pharmacol
, vol.73
, pp. 1367-1375
-
-
Schafer, A.1
Fraccarollo, D.2
Vogt, C.3
-
23
-
-
33747171728
-
Effect of therapy with rosuvastatin on lipid spectrum, factors of inflammation and endothelial function in patients with ischemic heart disease
-
Sergienko IV, Samoilenko E., Masenko VP, et al. Effect of therapy with rosuvastatin on lipid spectrum, factors of inflammation and endothelial function in patients with ischemic heart disease. Kardiologiia. 2006 ; 46: 4-8.
-
(2006)
Kardiologiia
, vol.46
, pp. 4-8
-
-
Sergienko, I.V.1
Samoilenko, E.2
Masenko, V.P.3
-
24
-
-
3142606890
-
Effect of rosuvastatin on plasma levels of asymmetric dimethylarginine in patients with hypercholesterolemia
-
Lu TM, Ding YA, Leu HB, Yin WH, Sheu WH, Chu KM Effect of rosuvastatin on plasma levels of asymmetric dimethylarginine in patients with hypercholesterolemia. Am J Cardiol. 2004 ; 94: 157-161.
-
(2004)
Am J Cardiol
, vol.94
, pp. 157-161
-
-
Lu, T.M.1
Ya, D.2
Leu, H.B.3
Yin, W.H.4
Sheu, W.H.5
Chu, K.M.6
-
25
-
-
40349115867
-
Rosuvastatin attenuates angiotensin II-induced neointimal formation after stent implantation in the rat
-
van der Harst P., Groenwegen HC, Roks AJ, et al. Rosuvastatin attenuates angiotensin II-induced neointimal formation after stent implantation in the rat. Coron Artery Dis. 2008 ; 19: 47-53.
-
(2008)
Coron Artery Dis
, vol.19
, pp. 47-53
-
-
Van Der Harst, P.1
Groenwegen, H.C.2
Roks, A.J.3
-
26
-
-
0035960605
-
Oxidant stress as a marker for cardiovascular events: Ox marks the spot
-
Landmesser U., Harrison DG Oxidant stress as a marker for cardiovascular events: Ox marks the spot. Circulation. 2001 ; 104: 2638-2640.
-
(2001)
Circulation
, vol.104
, pp. 2638-2640
-
-
Landmesser, U.1
Harrison, D.G.2
-
27
-
-
34948842028
-
Isoprenoid depletion by statins antagonizes cytokine-induced down-regulation of endothelial nitric oxide expression and increases NO synthase activity in human umbilical vein endothelial cells
-
Jantzen F., Koneman S., Wolff B., et al. Isoprenoid depletion by statins antagonizes cytokine-induced down-regulation of endothelial nitric oxide expression and increases NO synthase activity in human umbilical vein endothelial cells. J Physiol Pharmacol. 2007 ; 58: 503-514.
-
(2007)
J Physiol Pharmacol
, vol.58
, pp. 503-514
-
-
Jantzen, F.1
Koneman, S.2
Wolff, B.3
-
28
-
-
33644784922
-
Statins prevent dextrose-induced endothelial barrier dysfunction, possibly through inhibition of superoxide formation
-
Haas MJ, Horani MH, Parseghian SA, Mooradian AD Statins prevent dextrose-induced endothelial barrier dysfunction, possibly through inhibition of superoxide formation. Diabetes. 2006 ; 55: 474-479.
-
(2006)
Diabetes
, vol.55
, pp. 474-479
-
-
Haas, M.J.1
Horani, M.H.2
Parseghian, S.A.3
Mooradian, A.D.4
-
29
-
-
30044433591
-
Cross-talk between dyslipidemia and renin-angiotensin system and the role of LOX-1 and MAPK in atherogenesis studies with the combined use of rosuvastatin and candesartan
-
Chen J., Li D., Schaefer R., Mehta JL Cross-talk between dyslipidemia and renin-angiotensin system and the role of LOX-1 and MAPK in atherogenesis studies with the combined use of rosuvastatin and candesartan. Atherosclerosis. 2006 ; 184: 295-301.
-
(2006)
Atherosclerosis
, vol.184
, pp. 295-301
-
-
Chen, J.1
Li, D.2
Schaefer, R.3
Mehta, J.L.4
-
30
-
-
58049180113
-
Rosuvastatin prevents endothelial cell death and reduces atherosclerotic lesion formation in ApoE-deficient mice [published online ahead of print December 10, 2007]
-
Enomoto S., Sata M., Fukuda D., Nakamura K., Nagai R. Rosuvastatin prevents endothelial cell death and reduces atherosclerotic lesion formation in ApoE-deficient mice [published online ahead of print December 10, 2007]. Biomed Pharmacother. doi:10.1016/j.biopha.2007.11.002.
-
Biomed Pharmacother
-
-
Enomoto, S.1
Sata, M.2
Fukuda, D.3
Nakamura, K.4
Nagai, R.5
-
31
-
-
37849040502
-
Rosuvastatin increases vascular endothelial PPARgamma expression and corrects blood pressure variability in obese dyslipidaemic mice
-
Desjardins F., Sekkali B., Verreth W., et al. Rosuvastatin increases vascular endothelial PPARgamma expression and corrects blood pressure variability in obese dyslipidaemic mice. Eur Heart J. 2008 ; 29: 128-137.
-
(2008)
Eur Heart J
, vol.29
, pp. 128-137
-
-
Desjardins, F.1
Sekkali, B.2
Verreth, W.3
-
32
-
-
24144465868
-
Effect of rosuvastatin on insulin sensitivity in patients with familial combined hyperlipidaemia
-
ter Avest E., Abbink EJ, de Graaf J., Tack CJ, Stalenhoef AF Effect of rosuvastatin on insulin sensitivity in patients with familial combined hyperlipidaemia. Eur J Clin Invest. 2005 ; 35: 558-564.
-
(2005)
Eur J Clin Invest
, vol.35
, pp. 558-564
-
-
Ter Avest, E.1
Abbink, E.J.2
De Graaf, J.3
Tack, C.J.4
Stalenhoef, A.F.5
-
33
-
-
33644891902
-
Reduction of oxidative stress and modulation of autoantibodies against modified low-density lipoprotein after rosuvastatin therapy
-
Resch U., Tatzber F., Budinsky A., Sinzinger H. Reduction of oxidative stress and modulation of autoantibodies against modified low-density lipoprotein after rosuvastatin therapy. Br J Clin Pharmacol. 2006 ; 61: 262-274.
-
(2006)
Br J Clin Pharmacol
, vol.61
, pp. 262-274
-
-
Resch, U.1
Tatzber, F.2
Budinsky, A.3
Sinzinger, H.4
-
34
-
-
33745066138
-
Rosuvastatin treatment protects against nitrate-induced oxidative stress in eNOS knockout mice: Implication of the NAD(P)H oxidase pathway
-
Otto A., Fontaine J., Tschirhart E., Fontaine D., Berkenboom G. Rosuvastatin treatment protects against nitrate-induced oxidative stress in eNOS knockout mice: implication of the NAD(P)H oxidase pathway. Br J Pharmacol. 2006 ; 148: 544-552.
-
(2006)
Br J Pharmacol
, vol.148
, pp. 544-552
-
-
Otto, A.1
Fontaine, J.2
Tschirhart, E.3
Fontaine, D.4
Berkenboom, G.5
-
36
-
-
18044385575
-
Rosuvastatin attenuates monocyte-endothelial cell interactions and vascular free radical production in hypercholesterolemic mice
-
Li W., Asagami T., Matsushita H., Lee KH, Tsao PS Rosuvastatin attenuates monocyte-endothelial cell interactions and vascular free radical production in hypercholesterolemic mice. J Pharmacol Exp Ther. 2005 ; 313: 557-562.
-
(2005)
J Pharmacol Exp Ther
, vol.313
, pp. 557-562
-
-
Li, W.1
Asagami, T.2
Matsushita, H.3
Kh, L.4
Tsao, P.S.5
-
37
-
-
36348957437
-
Statin treatment increases formation of carbon monoxide and bilirubin in mice: A novel mechanism of in vivo antioxidant protection
-
Muchova L., Wong RJ, Hsu M., et al. Statin treatment increases formation of carbon monoxide and bilirubin in mice: a novel mechanism of in vivo antioxidant protection. Can J Physiol Pharmacol. 2007 ; 85: 800-810.
-
(2007)
Can J Physiol Pharmacol
, vol.85
, pp. 800-810
-
-
Muchova, L.1
Wong, R.J.2
Hsu, M.3
-
38
-
-
36048985355
-
Effect of rosuvastatin versus atorvastatin treatment on paraoxonase-1 activity in men with established cardiovascular disease and a low HDL-cholesterol
-
Bergheanu SC, van Tol A., Dallinga-Thie GM, et al. Effect of rosuvastatin versus atorvastatin treatment on paraoxonase-1 activity in men with established cardiovascular disease and a low HDL-cholesterol. Curr Med Res Opin. 2007 ; 23: 2235-2240.
-
(2007)
Curr Med Res Opin
, vol.23
, pp. 2235-2240
-
-
Bergheanu, S.C.1
Van Tol, A.2
Dallinga-Thie, G.M.3
-
39
-
-
33845616263
-
Antioxidant and antiplatelet effects of rosuvastatin in a hamster model of prediabetes
-
Miersch S., Sliskovic I., Raturi A., Mutus B. Antioxidant and antiplatelet effects of rosuvastatin in a hamster model of prediabetes. Free Radic Biol Med. 2007 ; 42: 270-279.
-
(2007)
Free Radic Biol Med
, vol.42
, pp. 270-279
-
-
Miersch, S.1
Sliskovic, I.2
Raturi, A.3
Mutus, B.4
-
40
-
-
47649111727
-
Rosuvastatin protects against oxidative stress and DNA damage in vitro via upregulation of glutathione synthesis [published online ahead of print December 21, 2007]
-
Schupp N., Schmid U., Heidland A., Stopper H. Rosuvastatin protects against oxidative stress and DNA damage in vitro via upregulation of glutathione synthesis [published online ahead of print December 21, 2007]. Atherosclerosis. doi:10.1016/j.atherosclerosis.2007.11.016.
-
Atherosclerosis
-
-
Schupp, N.1
Schmid, U.2
Heidland, A.3
Stopper, H.4
-
41
-
-
8444233164
-
Rosuvastatin upregulates the antioxidant defense protein heme oxygenase-1
-
Grosser N., Erdmann K., Hemmerle A., et al. Rosuvastatin upregulates the antioxidant defense protein heme oxygenase-1. Biochem Biophys Res Commun. 2004 ; 325: 871-876.
-
(2004)
Biochem Biophys Res Commun
, vol.325
, pp. 871-876
-
-
Grosser, N.1
Erdmann, K.2
Hemmerle, A.3
-
42
-
-
34447525009
-
Effects of rosuvastatin on 3-nitrotyrosine and aortic stiffness in hypercholesterolemia
-
Pirro M., Schillaci G., Mannarino MR, et al. Effects of rosuvastatin on 3-nitrotyrosine and aortic stiffness in hypercholesterolemia. Nutr Metab Cardiovasc Dis. 2007 ; 17: 436-441.
-
(2007)
Nutr Metab Cardiovasc Dis
, vol.17
, pp. 436-441
-
-
Pirro, M.1
Schillaci, G.2
Mannarino, M.R.3
-
43
-
-
33750531657
-
Lipid-altering efficacy of the ezetimibe/simvastatin single tablet versus rosuvastatin in hypercholesterolemic patients
-
Catapano AL, Davidson MH, Ballantyne CM, et al. Lipid-altering efficacy of the ezetimibe/simvastatin single tablet versus rosuvastatin in hypercholesterolemic patients. Curr Med Res Opin. 2006 ; 22: 2041-2053.
-
(2006)
Curr Med Res Opin
, vol.22
, pp. 2041-2053
-
-
Catapano, A.L.1
Davidson, M.H.2
Ballantyne, C.M.3
-
44
-
-
25644455999
-
Starting with rosuvastatin in primary hyperlipidemia-is there more than lipid lowering
-
Milionis HJ, Gazi IF, Filippatos TD, et al. Starting with rosuvastatin in primary hyperlipidemia-is there more than lipid lowering ? Angiology. 2005 ; 56: 585-592.
-
(2005)
Angiology
, vol.56
, pp. 585-592
-
-
Milionis, H.J.1
Gazi, I.F.2
Filippatos, T.D.3
-
45
-
-
33745714077
-
Treating to target patients with primary hyperlipidaemia: Comparison of the effects of ATOrvastatin and ROSuvastatin (the ATOROS study)
-
Milionis HJ, Rizos E., Kostapanos M., et al. Treating to target patients with primary hyperlipidaemia: comparison of the effects of ATOrvastatin and ROSuvastatin (the ATOROS study). Curr Med Res Opin. 2006 ; 22: 1123-1131.
-
(2006)
Curr Med Res Opin
, vol.22
, pp. 1123-1131
-
-
Milionis, H.J.1
Rizos, E.2
Kostapanos, M.3
-
46
-
-
33846593363
-
Rosuvastatin affecting aortic valve endothelium to slow the progression of aortic stenosis
-
Moura LM, Ramos SF, Zamorano JL, et al. Rosuvastatin affecting aortic valve endothelium to slow the progression of aortic stenosis. J Am Coll Cardiol. 2007 ; 49: 554-561.
-
(2007)
J Am Coll Cardiol
, vol.49
, pp. 554-561
-
-
Moura, L.M.1
Ramos, S.F.2
Zamorano, J.L.3
-
47
-
-
0242694573
-
Rosuvastatin in the primary prevention of cardiovascular disease among patients with low levels of low-density lipoprotein cholesterol and elevated high-sensitivity C-reactive protein: Rationale and design of the JUPITER trial
-
Ridker PM Rosuvastatin in the primary prevention of cardiovascular disease among patients with low levels of low-density lipoprotein cholesterol and elevated high-sensitivity C-reactive protein: rationale and design of the JUPITER trial. Circulation. 2003 ; 108: 2292-2297.
-
(2003)
Circulation
, vol.108
, pp. 2292-2297
-
-
Ridker, P.M.1
-
48
-
-
0141430989
-
Rosuvastatin reduces atherosclerosis development beyond and independent of its plasma cholesterol-lowering effect in APOE*3-Leiden transgenic mice: Evidence for antiinflammatory effects of rosuvastatin
-
Kleemann R., Princen HM, Emeis JJ, et al. Rosuvastatin reduces atherosclerosis development beyond and independent of its plasma cholesterol-lowering effect in APOE*3-Leiden transgenic mice: evidence for antiinflammatory effects of rosuvastatin. Circulation. 2003 ; 108: 1368-1374.
-
(2003)
Circulation
, vol.108
, pp. 1368-1374
-
-
Kleemann, R.1
Princen, H.M.2
Emeis, J.J.3
-
49
-
-
35148866515
-
Differential effect of hypolipidaemic drugs on lipoprotein-associated phospholipase A2
-
Saougos VG, Tambaki AP, Kalogirou M., et al. Differential effect of hypolipidaemic drugs on lipoprotein-associated phospholipase A2. Arterioscler Thromb Vasc Biol. 2007 ; 27: 2236-2243.
-
(2007)
Arterioscler Thromb Vasc Biol
, vol.27
, pp. 2236-2243
-
-
Saougos, V.G.1
Tambaki, A.P.2
Kalogirou, M.3
-
50
-
-
37349012116
-
Effect of rosuvastatin treatment on plasma visfatin levels in patients with primary hyperlipidemia
-
Kostapanos MS, Derdemezis CS, Filippatos TD, et al. Effect of rosuvastatin treatment on plasma visfatin levels in patients with primary hyperlipidemia. Eur J Pharmacol. 2007 ; 578: 249-252.
-
(2007)
Eur J Pharmacol
, vol.578
, pp. 249-252
-
-
Kostapanos, M.S.1
Derdemezis, C.S.2
Filippatos, T.D.3
-
51
-
-
33845642742
-
Rapid immunomodulation by rosuvastatin in patients with acute coronary syndrome
-
Link A., Ayadhi T., Bohm M., Nickenig G. Rapid immunomodulation by rosuvastatin in patients with acute coronary syndrome. Eur Heart J. 2006 ; 27: 2945-2955.
-
(2006)
Eur Heart J
, vol.27
, pp. 2945-2955
-
-
Link, A.1
Ayadhi, T.2
Bohm, M.3
Nickenig, G.4
-
52
-
-
34347244912
-
Rosuvastatin suppresses the inflammatory responses through inhibition of c-Jun N-terminal kinase and Nuclear Factor-kappaB in endothelial cells
-
Kim YS, Ahn Y., Hong MH, et al. Rosuvastatin suppresses the inflammatory responses through inhibition of c-Jun N-terminal kinase and Nuclear Factor-kappaB in endothelial cells. J Cardiovasc Pharmacol. 2007 ; 49: 376-383.
-
(2007)
J Cardiovasc Pharmacol
, vol.49
, pp. 376-383
-
-
Kim, Y.S.1
Ahn, Y.2
Hong, M.H.3
-
53
-
-
33644542699
-
Effects of rosuvastatin on postprandial leukocytes in mildly hyperlipidemic patients with premature coronary sclerosis
-
van Oostrom AJ, Plokker HW, van Asbeck BS, et al. Effects of rosuvastatin on postprandial leukocytes in mildly hyperlipidemic patients with premature coronary sclerosis. Atherosclerosis. 2006 ; 185: 331-339.
-
(2006)
Atherosclerosis
, vol.185
, pp. 331-339
-
-
Van Oostrom, A.J.1
Plokker, H.W.2
Van Asbeck, B.S.3
-
54
-
-
4644372391
-
Inhibitory effect of candesartan and rosuvastatin on CD40 and MMPs expression in apo-E knockout mice: Novel insights into the role of RAS and dyslipidemia in atherogenesis
-
Chen J., Li D., Schaefer RF, Mehta JL Inhibitory effect of candesartan and rosuvastatin on CD40 and MMPs expression in apo-E knockout mice: novel insights into the role of RAS and dyslipidemia in atherogenesis. J Cardiovasc Pharmacol. 2004 ; 44: 446-452.
-
(2004)
J Cardiovasc Pharmacol
, vol.44
, pp. 446-452
-
-
Chen, J.1
Li, D.2
Schaefer, R.F.3
Mehta, J.L.4
-
55
-
-
38149082716
-
Invivo effects of simvastatin and rosuvastatin on global gene expression in peripheral blood leucocytes in a human inflammation model
-
Schmidt WM, Spiel AO, Jilma B., Wolzt M., Müller M. Invivo effects of simvastatin and rosuvastatin on global gene expression in peripheral blood leucocytes in a human inflammation model. Pharmacogenet Genomics. 2008 ; 18: 109-120.
-
(2008)
Pharmacogenet Genomics
, vol.18
, pp. 109-120
-
-
Schmidt, W.M.1
Spiel, A.O.2
Jilma, B.3
Wolzt, M.4
Müller, M.5
-
56
-
-
34147152963
-
Rosuvastatin displays anti-atherothrombotic and anti-inflammatory properties in apoE-deficient mice
-
Monetti M., Canavesi M., Camera M., et al. Rosuvastatin displays anti-atherothrombotic and anti-inflammatory properties in apoE-deficient mice. Pharmacol Res. 2007 ; 55: 441-449.
-
(2007)
Pharmacol Res
, vol.55
, pp. 441-449
-
-
Monetti, M.1
Canavesi, M.2
Camera, M.3
-
57
-
-
0034753831
-
A new HMG-CoA reductase inhibitor, rosuvastatin, exerts anti-inflammatory effects on the microvascular endothelium: The role of mevalonic acid
-
Stalker TJ, Lefer AM, Scalia R. A new HMG-CoA reductase inhibitor, rosuvastatin, exerts anti-inflammatory effects on the microvascular endothelium: the role of mevalonic acid. Br J Pharmacol. 2001 ; 133: 406-412.
-
(2001)
Br J Pharmacol
, vol.133
, pp. 406-412
-
-
Stalker, T.J.1
Lefer, A.M.2
Scalia, R.3
-
58
-
-
2342536907
-
Rosuvastatin reduces MMP-7 secretion by human monocyte-derived macrophages: Potential relevance to atherosclerotic plaque stability
-
Furman C., Copin C., Kandoussi M., et al. Rosuvastatin reduces MMP-7 secretion by human monocyte-derived macrophages: potential relevance to atherosclerotic plaque stability. Atherosclerosis. 2004 ; 174: 93-98.
-
(2004)
Atherosclerosis
, vol.174
, pp. 93-98
-
-
Furman, C.1
Copin, C.2
Kandoussi, M.3
-
59
-
-
39249083201
-
Effect of rosuvastatin therapy on carotid plaque morphology and composition in moderately hypercholesterolemic patients: A high-resolution magnetic resonance imaging trial
-
Underhill HR, Yuan C., Zhao XQ, et al. Effect of rosuvastatin therapy on carotid plaque morphology and composition in moderately hypercholesterolemic patients: a high-resolution magnetic resonance imaging trial. Am Heart J. 2008 ; 155: 584.e1-e8.
-
(2008)
Am Heart J
, vol.155
-
-
Underhill, H.R.1
Yuan, C.2
Zhao, X.Q.3
-
60
-
-
0036790415
-
Bone marrow-derived progenitor cells modulate vascular reendothelialization and neointimal formation: Effect of 3-hydroxy-3- methylglutaryl coenzyme a reductase inhibition
-
Werner N PJ, Laufs U., Endres M., Böhm M., Dirnagl U., Nickenig G. Bone marrow-derived progenitor cells modulate vascular reendothelialization and neointimal formation: effect of 3-hydroxy-3-methylglutaryl coenzyme a reductase inhibition. Arterioscler Thromb Vasc Biol. 2002 ; 22: 1567-1572.
-
(2002)
Arterioscler Thromb Vasc Biol
, vol.22
, pp. 1567-1572
-
-
Werner, N.P.J.1
Laufs, U.2
Endres, M.3
Böhm, M.4
Dirnagl, U.5
Nickenig, G.6
-
61
-
-
33750931287
-
Highly active antiretroviral therapy attenuates re-endothelialization and alters neointima formation in the rat carotid artery after balloon injury
-
Kappert K., Leppanen O., Paulsson J., et al. Highly active antiretroviral therapy attenuates re-endothelialization and alters neointima formation in the rat carotid artery after balloon injury. J Acquir Immune Defic Syndr. 2006 ; 43: 383-392.
-
(2006)
J Acquir Immune Defic Syndr
, vol.43
, pp. 383-392
-
-
Kappert, K.1
Leppanen, O.2
Paulsson, J.3
-
62
-
-
23644437626
-
Suppression of endothelial progenitor cells in human coronary artery disease by the endogenous nitric oxide synthase inhibitor asymmetric dimethylarginine
-
Thum T., Tsikas D., Stein S., et al. Suppression of endothelial progenitor cells in human coronary artery disease by the endogenous nitric oxide synthase inhibitor asymmetric dimethylarginine. J Am Coll Cardiol. 2005 ; 46: 1693-1701.
-
(2005)
J Am Coll Cardiol
, vol.46
, pp. 1693-1701
-
-
Thum, T.1
Tsikas, D.2
Stein, S.3
-
63
-
-
36049013751
-
Rosuvastatin regulates vascular smooth muscle cell phenotypic modulation in vascular remodeling: Role for the urokinase receptor
-
Kiyan J., Kusch A., Tkachuk S., et al. Rosuvastatin regulates vascular smooth muscle cell phenotypic modulation in vascular remodeling: role for the urokinase receptor. Atherosclerosis. 2007 ; 195: 254-261.
-
(2007)
Atherosclerosis
, vol.195
, pp. 254-261
-
-
Kiyan, J.1
Kusch, A.2
Tkachuk, S.3
-
64
-
-
33847068210
-
Different migration of vascular smooth muscle cells from human coronary artery bypass vessels. Role of Rho/ROCK pathway
-
Weiss S., Frischknecht K., Greutert H., et al. Different migration of vascular smooth muscle cells from human coronary artery bypass vessels. Role of Rho/ROCK pathway. J Vasc Res. 2007 ; 44: 149-156.
-
(2007)
J Vasc Res
, vol.44
, pp. 149-156
-
-
Weiss, S.1
Frischknecht, K.2
Greutert, H.3
-
65
-
-
12344273558
-
Rosuvastatin exerts favourable effects on thrombosis and neointimal growth in a mouse model of endothelial injury
-
Schafer K., Kaiser K., Konstantinides S. Rosuvastatin exerts favourable effects on thrombosis and neointimal growth in a mouse model of endothelial injury. Thromb Haemost. 2005 ; 93: 145-152.
-
(2005)
Thromb Haemost
, vol.93
, pp. 145-152
-
-
Schafer, K.1
Kaiser, K.2
Konstantinides, S.3
-
66
-
-
34249697077
-
Rosuvastatin restores superoxide dismutase expression and inhibits accumulation of oxidized LDL in the aortic arch of obese dyslipidemic mice
-
Verreth W., De Keyzer D., Davey PC, et al. Rosuvastatin restores superoxide dismutase expression and inhibits accumulation of oxidized LDL in the aortic arch of obese dyslipidemic mice. Br J Pharmacol. 2007 ; 151: 347-355.
-
(2007)
Br J Pharmacol
, vol.151
, pp. 347-355
-
-
Verreth, W.1
De Keyzer, D.2
Davey, P.C.3
-
67
-
-
44949097585
-
The effect of rosuvastatin treatment on the mean platelet volume in patients with uncontrolled primary dyslipidemia with hypolipidemic diet treatment
-
Coban E Md, Afacan B. The effect of rosuvastatin treatment on the mean platelet volume in patients with uncontrolled primary dyslipidemia with hypolipidemic diet treatment. Platelets. 2007 ; 23: 1-4.
-
(2007)
Platelets
, vol.23
, pp. 1-4
-
-
Md, C.E.1
Afacan, B.2
-
68
-
-
33646065014
-
Effect of statins on platelet PAR-1 thrombin receptor in patients with the metabolic syndrome (from the PAR-1 inhibition by statins [PARIS] study)
-
Serebruany VL, Miller M., Pokov AN, et al. Effect of statins on platelet PAR-1 thrombin receptor in patients with the metabolic syndrome (from the PAR-1 inhibition by statins [PARIS] study). Am J Cardiol. 2006 ; 97: 1332-1336.
-
(2006)
Am J Cardiol
, vol.97
, pp. 1332-1336
-
-
Serebruany, V.L.1
Miller, M.2
Pokov, A.N.3
-
69
-
-
38349163794
-
The HMG-CoA reductase inhibitor rosuvastatin inhibits plasminogen activator inhibitor-1 expression and secretion in human adipocytes
-
Laumen H., Skurk T., Hauner H. The HMG-CoA reductase inhibitor rosuvastatin inhibits plasminogen activator inhibitor-1 expression and secretion in human adipocytes. Atherosclerosis. 2008 ; 196: 565-573.
-
(2008)
Atherosclerosis
, vol.196
, pp. 565-573
-
-
Laumen, H.1
Skurk, T.2
Hauner, H.3
-
70
-
-
40949136571
-
Effect of rosuvastatin on insulin sensitivity in an animal model of insulin resistance: Evidence for statin-induced hepatic insulin sensitization
-
Naples M., Federico LM, Xu E., Nelken J., Adeli K. Effect of rosuvastatin on insulin sensitivity in an animal model of insulin resistance: evidence for statin-induced hepatic insulin sensitization. Atherosclerosis. 2008 ; 198: 94-103.
-
(2008)
Atherosclerosis
, vol.198
, pp. 94-103
-
-
Naples, M.1
Federico, L.M.2
Xu, E.3
Nelken, J.4
Adeli, K.5
-
71
-
-
11844249295
-
Comparative effects of rosuvastatin and gemfibrozil on glucose, insulin, and lipid metabolism in insulin-resistant, nondiabetic patients with combined dyslipidemia
-
Lamendola C., Abbasi F., Chu JW, et al. Comparative effects of rosuvastatin and gemfibrozil on glucose, insulin, and lipid metabolism in insulin-resistant, nondiabetic patients with combined dyslipidemia. Am J Cardiol. 2005 ; 95: 189-193.
-
(2005)
Am J Cardiol
, vol.95
, pp. 189-193
-
-
Lamendola, C.1
Abbasi, F.2
Chu, J.W.3
-
72
-
-
13444272966
-
Oral pre-treatment with rosuvastatin protects porcine myocardium from ischaemia/reperfusion injury via a mechanism related to nitric oxide but not to serum cholesterol level
-
Bulhak AA, Gourine AV, Gonon AT, Sjoquist PO, Valen G., Pernow J. Oral pre-treatment with rosuvastatin protects porcine myocardium from ischaemia/reperfusion injury via a mechanism related to nitric oxide but not to serum cholesterol level. Acta Physiol Scand. 2005 ; 183: 151-159.
-
(2005)
Acta Physiol Scand
, vol.183
, pp. 151-159
-
-
Aa, B.1
Gourine, A.V.2
Gonon, A.T.3
Sjoquist, P.O.4
Valen, G.5
Pernow, J.6
-
73
-
-
19444368584
-
Chronic treatment with rosuvastatin modulates nitric oxide synthase expression and reduces ischemia-reperfusion injury in rat hearts
-
Di Napoli P., Taccardi AA, Grilli A., et al. Chronic treatment with rosuvastatin modulates nitric oxide synthase expression and reduces ischemia-reperfusion injury in rat hearts. Cardiovasc Res. 2005 ; 66: 462-471.
-
(2005)
Cardiovasc Res
, vol.66
, pp. 462-471
-
-
Di Napoli, P.1
Aa, T.2
Grilli, A.3
-
74
-
-
15744385725
-
Rosuvastatin reduces experimental left ventricular infarct size after ischemia-reperfusion injury but not total coronary occlusion
-
Weinberg EO, Scherrer-Crosbie M., Picard MH, et al. Rosuvastatin reduces experimental left ventricular infarct size after ischemia-reperfusion injury but not total coronary occlusion. Am J Physiol Heart Circ Physiol. 2005 ; 288: H1802 - H1809.
-
(2005)
Am J Physiol Heart Circ Physiol
, vol.288
-
-
Weinberg, E.O.1
Scherrer-Crosbie, M.2
Picard, M.H.3
-
75
-
-
0037130769
-
Direct vascular and cardioprotective effects of rosuvastatin, a new HMG-CoA reductase inhibitor
-
Jones SP, Gibson MF, Rimmer DM 3rd, Gibson TM, Sharp BR, Lefer DJ Direct vascular and cardioprotective effects of rosuvastatin, a new HMG-CoA reductase inhibitor. J Am Coll Cardiol. 2002 ; 40: 1172-1178.
-
(2002)
J Am Coll Cardiol
, vol.40
, pp. 1172-1178
-
-
Jones, S.P.1
Gibson, M.F.2
Rimmer III, D.M.3
Gibson, T.M.4
Sharp, B.R.5
Lefer, D.J.6
-
76
-
-
0037381031
-
Rosuvastatin, a new HMG-CoA reductase inhibitor, protects ischemic reperfused myocardium in normocholesterolemic rats
-
Ikeda Y., Young LH, Lefer AM Rosuvastatin, a new HMG-CoA reductase inhibitor, protects ischemic reperfused myocardium in normocholesterolemic rats. J Cardiovasc Pharmacol. 2003 ; 41: 649-656.
-
(2003)
J Cardiovasc Pharmacol
, vol.41
, pp. 649-656
-
-
Ikeda, Y.1
Young, L.H.2
Lefer, A.M.3
-
77
-
-
34447517167
-
Cardioprotective effect of rosuvastatin in vivo is dependent on inhibition of geranylgeranyl pyrophosphate and altered RhoA membrane translocation
-
Bulhak A., Roy J., Hedin U., Sjoquist PO, Pernow J. Cardioprotective effect of rosuvastatin in vivo is dependent on inhibition of geranylgeranyl pyrophosphate and altered RhoA membrane translocation. Am J Physiol Heart Circ Physiol. 2007 ; 292: H3158 - H3163.
-
(2007)
Am J Physiol Heart Circ Physiol
, vol.292
-
-
Bulhak, A.1
Roy, J.2
Hedin, U.3
Sjoquist, P.O.4
Pernow, J.5
-
78
-
-
33745183117
-
Association of RhoGDIalpha with Rac1 GTPase mediates free radical production during myocardial hypertrophy
-
Custodis F., Eberl M., Kilter H., Bohm M., Laufs U. Association of RhoGDIalpha with Rac1 GTPase mediates free radical production during myocardial hypertrophy. Cardiovasc Res. 2006 ; 71: 342-351.
-
(2006)
Cardiovasc Res
, vol.71
, pp. 342-351
-
-
Custodis, F.1
Eberl, M.2
Kilter, H.3
Bohm, M.4
Laufs, U.5
-
79
-
-
0035186999
-
Statins as antioxidant therapy for preventing cardiac myocyte hypertrophy
-
Takemoto M., Node K., Nakagami H., et al. Statins as antioxidant therapy for preventing cardiac myocyte hypertrophy. J Clin Invest. 2001 ; 108: 1429-1437.
-
(2001)
J Clin Invest
, vol.108
, pp. 1429-1437
-
-
Takemoto, M.1
Node, K.2
Nakagami, H.3
-
80
-
-
0141841614
-
Oxygen free radical release in human failing myocardium is associated with increased activity of rac1-GTPase and represents a target for statin treatment
-
Maack C., Kartes T., Kilter H., et al. Oxygen free radical release in human failing myocardium is associated with increased activity of rac1-GTPase and represents a target for statin treatment. Circulation. 2003 ; 108: 1567-1574.
-
(2003)
Circulation
, vol.108
, pp. 1567-1574
-
-
Maack, C.1
Kartes, T.2
Kilter, H.3
-
81
-
-
0036791698
-
Activation of NADPH oxidase during progression of cardiac hypertrophy to failure
-
Li JM, Gall NP, Grieve DJ, Chen M., Shah AM Activation of NADPH oxidase during progression of cardiac hypertrophy to failure. Hypertension. 2002 ; 40: 477-484.
-
(2002)
Hypertension
, vol.40
, pp. 477-484
-
-
Li, J.M.1
Gall, N.P.2
Grieve, D.J.3
Chen, M.4
Shah, A.M.5
-
82
-
-
0030611196
-
RhoGDIgamma: A GDPdissociation inhibitor for Rho proteins with preferential expression in brain and pancreas
-
Adra CN, Manor D., Ko JL, et al. RhoGDIgamma: a GDPdissociation inhibitor for Rho proteins with preferential expression in brain and pancreas. Proc Natl Acad Sci U S A. 1997 ; 94: 4279-4284.
-
(1997)
Proc Natl Acad Sci U S a
, vol.94
, pp. 4279-4284
-
-
Adra, C.N.1
Manor, D.2
Ko, J.L.3
-
83
-
-
34249804809
-
Rosuvastatin, a 3-hydroxy-3-methylglutaryl coenzyme a reductase inhibitor, decreases cardiac oxidative stress and remodeling in Ren2 transgenic rats
-
Habibi J., Whaley-Connell A., Qazi MA, et al. Rosuvastatin, a 3-hydroxy-3-methylglutaryl coenzyme a reductase inhibitor, decreases cardiac oxidative stress and remodeling in Ren2 transgenic rats. Endocrinology. 2007 ; 148: 2181-2188.
-
(2007)
Endocrinology
, vol.148
, pp. 2181-2188
-
-
Habibi, J.1
Whaley-Connell, A.2
Ma, Q.3
-
84
-
-
39149143680
-
Rosuvastatin provides pleiotropic protection against pulmonary hypertension, right ventricular hypertrophy, and coronary endothelial dysfunction in rats
-
Sun X., Ku DD Rosuvastatin provides pleiotropic protection against pulmonary hypertension, right ventricular hypertrophy, and coronary endothelial dysfunction in rats. Am J Physiol Heart Circ Physiol. 2008 ; 294: H801 - H809.
-
(2008)
Am J Physiol Heart Circ Physiol
, vol.294
-
-
Sun, X.1
Ku, D.D.2
-
85
-
-
33748174097
-
3-HMG-Coenzyme a reductase inhibition and extracellular matrix gene expression in the pressure-overloaded rat heart
-
Cirrincione GM, Boluyt MO, Hwang HS, Bleske BE 3-HMG-Coenzyme A reductase inhibition and extracellular matrix gene expression in the pressure-overloaded rat heart. J Cardiovasc Pharmacol. 2006 ; 47: 521-530.
-
(2006)
J Cardiovasc Pharmacol
, vol.47
, pp. 521-530
-
-
Cirrincione, G.M.1
Boluyt, M.O.2
Hwang, H.S.3
Bleske, B.E.4
-
86
-
-
33847309058
-
Double-blind, randomized, placebo-controlled study of high-dose HMG CoA reductase inhibitor therapy on ventricular remodeling, pro-inflammatory cytokines and neurohormonal parameters in patients with chronic systolic heart failure
-
Krum H., Ashton E., Reid C., et al. Double-blind, randomized, placebo-controlled study of high-dose HMG CoA reductase inhibitor therapy on ventricular remodeling, pro-inflammatory cytokines and neurohormonal parameters in patients with chronic systolic heart failure. J Card Fail. 2007 ; 13: 1-7.
-
(2007)
J Card Fail
, vol.13
, pp. 1-7
-
-
Krum, H.1
Ashton, E.2
Reid, C.3
-
87
-
-
0038179586
-
Rosuvastatin decreases caveolin-1 and improves nitric oxide-dependent heart rate and blood pressure variability in apolipoprotein E-/- mice in vivo
-
Pelat M., Dessy C., Massion P., Desager JP, Feron O., Balligand JL Rosuvastatin decreases caveolin-1 and improves nitric oxide-dependent heart rate and blood pressure variability in apolipoprotein E-/- mice in vivo. Circulation. 2003 ; 107: 2480-2486.
-
(2003)
Circulation
, vol.107
, pp. 2480-2486
-
-
Pelat, M.1
Dessy, C.2
Massion, P.3
Desager, J.P.4
Feron, O.5
Balligand, J.L.6
-
88
-
-
0036179620
-
Blood pressure variability and organ damage in a general population: Results from the PAMELA study (Pressioni Arteriose Monitorate e Loro Associazioni)
-
Sega R., Corrao G., Bombelli M., et al. Blood pressure variability and organ damage in a general population: results from the PAMELA study (Pressioni Arteriose Monitorate E Loro Associazioni). Hypertension. 2002 ; 39: 710-714.
-
(2002)
Hypertension
, vol.39
, pp. 710-714
-
-
Sega, R.1
Corrao, G.2
Bombelli, M.3
-
89
-
-
0034362239
-
Role of nitric oxide in buffering short-term blood pressure fluctuations
-
Stauss HM, Persson PB Role of nitric oxide in buffering short-term blood pressure fluctuations. News Physiol Sci. 2000 ; 15: 229-233.
-
(2000)
News Physiol Sci
, vol.15
, pp. 229-233
-
-
Stauss, H.M.1
Persson, P.B.2
-
90
-
-
39449126531
-
Early impairment of left ventricular function in hypercholesterolemia and its reversibility after short term treatment with rosuvastatin. a preliminary echocardiographic study
-
Talini E., DiBello V., Bianchi C., et al. Early impairment of left ventricular function in hypercholesterolemia and its reversibility after short term treatment with rosuvastatin. A preliminary echocardiographic study. Atherosclerosis. 2008 ; 197: 346-354.
-
(2008)
Atherosclerosis
, vol.197
, pp. 346-354
-
-
Talini, E.1
Dibello, V.2
Bianchi, C.3
-
91
-
-
36549030340
-
CORONA Group. Rosuvastatin in older patients with systolic heart failure
-
Kjekshus J., Apetrei E., Barrios V.,, et al. CORONA Group. Rosuvastatin in older patients with systolic heart failure. N Engl J Med. 2007 ; 357: 2248-2261.
-
(2007)
N Engl J Med
, vol.357
, pp. 2248-2261
-
-
Kjekshus, J.1
Apetrei, E.2
Barrios, V.3
-
92
-
-
0037189048
-
Rosuvastatin, a new HMG-CoA reductase inhibitor, upregulates endothelial nitric oxide synthase and protects from ischemic stroke in mice
-
Laufs U., Gertz K., Dirnagl U., Bohm M., Nickenig G., Endres M. Rosuvastatin, a new HMG-CoA reductase inhibitor, upregulates endothelial nitric oxide synthase and protects from ischemic stroke in mice. Brain Res. 2002 ; 942: 23-30.
-
(2002)
Brain Res
, vol.942
, pp. 23-30
-
-
Laufs, U.1
Gertz, K.2
Dirnagl, U.3
Bohm, M.4
Nickenig, G.5
Endres, M.6
-
93
-
-
41749088284
-
The protective effect of rosuvastatin on ischemic brain injury and its mechanism
-
Xing H., Sun S., Mei Y., Herman D. The protective effect of rosuvastatin on ischemic brain injury and its mechanism. J Huazhong Univ Sci Technolog Med Sci. 2006 ; 26: 667-669.
-
(2006)
J Huazhong Univ Sci Technolog Med Sci
, vol.26
, pp. 667-669
-
-
Xing, H.1
Sun, S.2
Mei, Y.3
Herman, D.4
-
94
-
-
33747784874
-
Reduction of cerebral infarct size by the AT1-receptor blocker candesartan, the HMG-CoA reductase inhibitor rosuvastatin and their combination. An experimental study in rats
-
Engelhorn T., Doerfler A., Heusch G., Schulz R. Reduction of cerebral infarct size by the AT1-receptor blocker candesartan, the HMG-CoA reductase inhibitor rosuvastatin and their combination. An experimental study in rats. Neurosci Lett. 2006 ; 406: 92-96.
-
(2006)
Neurosci Lett
, vol.406
, pp. 92-96
-
-
Engelhorn, T.1
Doerfler, A.2
Heusch, G.3
Schulz, R.4
-
95
-
-
39349090619
-
Intravenous rosuvastatin for acute stroke treatment: An animal study
-
Prinz V., Laufs U., Gertz K., et al. Intravenous rosuvastatin for acute stroke treatment: an animal study. Stroke. 2008 ; 39: 433-438.
-
(2008)
Stroke
, vol.39
, pp. 433-438
-
-
Prinz, V.1
Laufs, U.2
Gertz, K.3
-
96
-
-
23644460358
-
Post-ischemic delivery of the 3-hydroxy-3-methylglutaryl coenzyme a reductase inhibitor rosuvastatin protects against focal cerebral ischemia in mice via inhibition of extracellular-regulated kinase-1/-2
-
Kilic U., Bassetti CL, Kilic E., Xing H., Wang Z., Hermann DM Post-ischemic delivery of the 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor rosuvastatin protects against focal cerebral ischemia in mice via inhibition of extracellular-regulated kinase-1/-2. Neuroscience. 2005 ; 134: 901-906.
-
(2005)
Neuroscience
, vol.134
, pp. 901-906
-
-
Kilic, U.1
Bassetti, C.L.2
Kilic, E.3
Xing, H.4
Wang, Z.5
Hermann, D.M.6
-
97
-
-
12844276482
-
Aggravation of focal cerebral ischemia by tissue plasminogen activator is reversed by 3-hydroxy-3-methylglutaryl coenzyme a reductase inhibitor but does not depend on endothelial NO synthase
-
Kilic E., Kilic U., Matter CM, Luscher TF, Bassetti CL, Hermann DM Aggravation of focal cerebral ischemia by tissue plasminogen activator is reversed by 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor but does not depend on endothelial NO synthase. Stroke. 2005 ; 36: 332-336.
-
(2005)
Stroke
, vol.36
, pp. 332-336
-
-
Kilic, E.1
Kilic, U.2
Matter, C.M.3
Luscher, T.F.4
Bassetti, C.L.5
Hermann, D.M.6
-
98
-
-
0346749450
-
3-hydroxy-3-methylglutaryl coenzyme a reductase inhibitors protect cortical neurons from excitotoxicity
-
Zacco A., Togo J., Spence K., et al. 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors protect cortical neurons from excitotoxicity. J Neurosci. 2003 ; 23: 11104-11111.
-
(2003)
J Neurosci
, vol.23
, pp. 11104-11111
-
-
Zacco, A.1
Togo, J.2
Spence, K.3
-
99
-
-
33645732870
-
Rosuvastatin improves cerebrovascular function in Zucker obese rats by inhibiting NAD(P)H oxidase-dependent superoxide production
-
Erdos B., Snipes JA, Tulbert CD, Katakam P., Miller AW, Busija DW Rosuvastatin improves cerebrovascular function in Zucker obese rats by inhibiting NAD(P)H oxidase-dependent superoxide production. Am J Physiol Heart Circ Physiol. 2006 ; 290: H1264 - H1270.
-
(2006)
Am J Physiol Heart Circ Physiol
, vol.290
-
-
Erdos, B.1
Snipes, J.A.2
Tulbert, C.D.3
Katakam, P.4
Miller, A.W.5
Busija, D.W.6
-
100
-
-
33645944368
-
Tissue-specific effects of statins on the expression of heme oxygenase-1 in vivo
-
Hsu M., Muchova L., Morioka I., Wong RJ, Schroder H., Stevenson DK Tissue-specific effects of statins on the expression of heme oxygenase-1 in vivo. Biochem Biophys Res Commun. 2006 ; 343: 738-744.
-
(2006)
Biochem Biophys Res Commun
, vol.343
, pp. 738-744
-
-
Hsu, M.1
Muchova, L.2
Morioka, I.3
Wong, R.J.4
Schroder, H.5
Stevenson, D.K.6
-
101
-
-
14644432487
-
Rosuvastatin, but not simvastatin, provides end-organ protection in stroke-prone rats by antiinflammatory effects
-
Sironi L., Gianazza E., Gelosa P., et al. Rosuvastatin, but not simvastatin, provides end-organ protection in stroke-prone rats by antiinflammatory effects. Arterioscler Thromb Vasc Biol. 2005 ; 25: 598-603.
-
(2005)
Arterioscler Thromb Vasc Biol
, vol.25
, pp. 598-603
-
-
Sironi, L.1
Gianazza, E.2
Gelosa, P.3
-
102
-
-
7444229915
-
Rosuvastatin reduces caspase-3 activity and up-regulates alpha-secretase in human neuroblastoma SH-SY5Y cells exposed to a beta
-
Famer D., Crisby M. Rosuvastatin reduces caspase-3 activity and up-regulates alpha-secretase in human neuroblastoma SH-SY5Y cells exposed to A beta. Neurosci Lett. 2004 ; 371: 209-214.
-
(2004)
Neurosci Lett
, vol.371
, pp. 209-214
-
-
Famer, D.1
Crisby, M.2
-
103
-
-
0042837889
-
Caspase activation in the limbic cortex of subjects with early Alzheimer's disease
-
Gastard MC, Troncoso JC, Koliatsos VE Caspase activation in the limbic cortex of subjects with early Alzheimer's disease. Ann Neurol. 2003 ; 54: 393-398.
-
(2003)
Ann Neurol
, vol.54
, pp. 393-398
-
-
Gastard, M.C.1
Troncoso, J.C.2
Koliatsos, V.E.3
-
104
-
-
0035066332
-
Alzheimer's disease: Genes, proteins, and therapy
-
Selkoe DJ Alzheimer's disease: genes, proteins, and therapy. Physiol Rev. 2001 ; 81: 741-766.
-
(2001)
Physiol Rev
, vol.81
, pp. 741-766
-
-
Selkoe, D.J.1
-
105
-
-
0037110424
-
The role of macrophage/microglia and astrocytes in the pathogenesis of three neurologic disorders: HIV-associated dementia, Alzheimer disease, and multiple sclerosis
-
Minagar A., Shapshak P., Fujimura R., Ownby R., Heyes M., Eisdorfer C. The role of macrophage/microglia and astrocytes in the pathogenesis of three neurologic disorders: HIV-associated dementia, Alzheimer disease, and multiple sclerosis. J Neurol Sci. 2002 ; 202: 13-23.
-
(2002)
J Neurol Sci
, vol.202
, pp. 13-23
-
-
Minagar, A.1
Shapshak, P.2
Fujimura, R.3
Ownby, R.4
Heyes, M.5
Eisdorfer, C.6
-
106
-
-
34247891579
-
Rosuvastatin reduces gliosis and the accelerated weight gain observed in WT and ApoE-/mice exposed to a high cholesterol diet
-
Famer D., Crisby M. Rosuvastatin reduces gliosis and the accelerated weight gain observed in WT and ApoE-/mice exposed to a high cholesterol diet. Neurosci Lett. 2007 ; 419: 68-73.
-
(2007)
Neurosci Lett
, vol.419
, pp. 68-73
-
-
Famer, D.1
Crisby, M.2
-
107
-
-
34248208657
-
Effects of statins on alpha7 nicotinic receptor, cholinesterase and alpha-form of secreted amyloid precursor peptide in SH-SY5Y cells
-
Roensch J., Crisby M., Nordberg A., Xiao Y., Zhang LJ, Guan ZZ Effects of statins on alpha7 nicotinic receptor, cholinesterase and alpha-form of secreted amyloid precursor peptide in SH-SY5Y cells. Neurochem Int. 2007 ; 50: 800-806.
-
(2007)
Neurochem Int
, vol.50
, pp. 800-806
-
-
Roensch, J.1
Crisby, M.2
Nordberg, A.3
Xiao, Y.4
Zhang, L.J.5
Guan, Z.Z.6
-
108
-
-
21844474541
-
Neuronal nitric oxide synthase mediates statin-induced restoration of vasa nervorum and reversal of diabetic neuropathy
-
Ii M., Nishimura H., Kusano KF, et al. Neuronal nitric oxide synthase mediates statin-induced restoration of vasa nervorum and reversal of diabetic neuropathy. Circulation. 2005 ; 112: 93-102.
-
(2005)
Circulation
, vol.112
, pp. 93-102
-
-
Ii, M.1
Nishimura, H.2
Kusano, K.F.3
-
109
-
-
39449106400
-
Attenuation of vascular/neural dysfunction in Zucker rats treated with enalapril or rosuvastatin
-
Oltman CL, Davidson EP, Coppey LJ, Kleinschmidt TL, Lund DD, Yorek MA Attenuation of vascular/neural dysfunction in Zucker rats treated with enalapril or rosuvastatin. Obesity (Silver Spring). 2008 ; 16: 82-89.
-
(2008)
Obesity (Silver Spring)
, vol.16
, pp. 82-89
-
-
Oltman, C.L.1
Davidson, E.P.2
Coppey, L.J.3
Kleinschmidt, T.L.4
Lund, D.D.5
Ma, Y.6
-
110
-
-
37349043715
-
Vascular and neural dysfunction in Zucker diabetic fatty rats: A difficult condition to reverse
-
Oltman CL, Davidson EP, Coppey LJ, et al. Vascular and neural dysfunction in Zucker diabetic fatty rats: a difficult condition to reverse. Diabetes Obes Metab. 2008 ; 10: 64-74.
-
(2008)
Diabetes Obes Metab
, vol.10
, pp. 64-74
-
-
Oltman, C.L.1
Davidson, E.P.2
Coppey, L.J.3
-
111
-
-
33646701223
-
Effect of short-term rosuvastatin treatment on estimated glomerular filtration rate
-
Vidt DG, Harris S., McTaggart F., Ditmarsch M., Sager PT, Sorof JM Effect of short-term rosuvastatin treatment on estimated glomerular filtration rate. Am J Cardiol. 2006 ; 97: 1602-1606.
-
(2006)
Am J Cardiol
, vol.97
, pp. 1602-1606
-
-
Vidt, D.G.1
Harris, S.2
McTaggart, F.3
Ditmarsch, M.4
Sager, P.T.5
Sorof, J.M.6
-
112
-
-
1842829905
-
Rosuvastatin-induced arrest in progression of renal disease
-
Vidt DG, Cressman MD, Harris S., Pears JS, Hutchinson HG Rosuvastatin-induced arrest in progression of renal disease. Cardiology. 2004 ; 102: 52-60.
-
(2004)
Cardiology
, vol.102
, pp. 52-60
-
-
Vidt, D.G.1
Cressman, M.D.2
Harris, S.3
Pears, J.S.4
Hutchinson, H.G.5
-
113
-
-
27144534466
-
Effect of rosuvastatin on C-reactive protein and renal function in patients with chronic kidney disease
-
Verma A., Ranganna KM, Reddy RS, Verma M., Gordon NF Effect of rosuvastatin on C-reactive protein and renal function in patients with chronic kidney disease. Am J Cardiol. 2005 ; 96: 1290-1292.
-
(2005)
Am J Cardiol
, vol.96
, pp. 1290-1292
-
-
Verma, A.1
Ranganna, K.M.2
Reddy, R.S.3
Verma, M.4
Gordon, N.F.5
-
114
-
-
33645288571
-
Effect of rosuvastatin or atorvastatin on urinary albumin excretion and renal function in type 2 diabetic patients
-
Sorof J., Berne C., Siewert-Delle A., Jorgensen L., Sager P. Effect of rosuvastatin or atorvastatin on urinary albumin excretion and renal function in type 2 diabetic patients. Diabetes Res Clin Pract. 2006 ; 72: 81-87.
-
(2006)
Diabetes Res Clin Pract
, vol.72
, pp. 81-87
-
-
Sorof, J.1
Berne, C.2
Siewert-Delle, A.3
Jorgensen, L.4
Sager, P.5
-
115
-
-
33749866051
-
Rosuvastatin increases alpha-1 microglobulin urinary excretion in patients with primary dyslipidemia
-
Kostapanos MS, Milionis HJ, Gazi I., Kostara C., Bairaktari ET, Elisaf M. Rosuvastatin increases alpha-1 microglobulin urinary excretion in patients with primary dyslipidemia. J Clin Pharmacol. 2006 ; 46: 1337-1343.
-
(2006)
J Clin Pharmacol
, vol.46
, pp. 1337-1343
-
-
Kostapanos, M.S.1
Milionis, H.J.2
Gazi, I.3
Kostara, C.4
Bairaktari, E.T.5
Elisaf, M.6
-
116
-
-
37249013533
-
Dose-dependent effect of rosuvastatin treatment on urinary protein excretion
-
Kostapanos MS, Milionis HJ, Saougos VG, et al. Dose-dependent effect of rosuvastatin treatment on urinary protein excretion. J Cardiovasc Pharmacol Ther. 2007 ; 12: 292-297.
-
(2007)
J Cardiovasc Pharmacol Ther
, vol.12
, pp. 292-297
-
-
Kostapanos, M.S.1
Milionis, H.J.2
Saougos, V.G.3
-
117
-
-
34247893910
-
Rosuvastatin treatment prevents progressive kidney inflammation and fibrosis in stroke-prone rats
-
Gianella A., Nobili E., Abbate M., et al. Rosuvastatin treatment prevents progressive kidney inflammation and fibrosis in stroke-prone rats. Am J Pathol. 2007 ; 170: 1165-1177.
-
(2007)
Am J Pathol
, vol.170
, pp. 1165-1177
-
-
Gianella, A.1
Nobili, E.2
Abbate, M.3
-
118
-
-
36249017958
-
Insulin resistance, oxidative stress, and podocyte injury: Role of rosuvastatin modulation of filtration barrier injury
-
Whaley-Connell A., DeMarco VG, Lastra G., et al. Insulin resistance, oxidative stress, and podocyte injury: role of rosuvastatin modulation of filtration barrier injury. Am J Nephrol. 2008 ; 28: 67-75.
-
(2008)
Am J Nephrol
, vol.28
, pp. 67-75
-
-
Whaley-Connell, A.1
Demarco, V.G.2
Lastra, G.3
-
119
-
-
38549135458
-
Attenuation of NADPH oxidase activation and glomerular filtration barrier remodeling with statin treatment
-
Whaley-Connell A., Habibi J., Nistala R., et al. Attenuation of NADPH oxidase activation and glomerular filtration barrier remodeling with statin treatment. Hypertension. 2008 ; 51: 474-480.
-
(2008)
Hypertension
, vol.51
, pp. 474-480
-
-
Whaley-Connell, A.1
Habibi, J.2
Nistala, R.3
-
120
-
-
44949135069
-
Rosuvastatin is additive to high-dose candesartan in slowing progression of experimental mesangioproliferative glomerulosclerosis
-
Krämer S., Kron S., Wang-Rosenke Y., et al. Rosuvastatin is additive to high-dose candesartan in slowing progression of experimental mesangioproliferative glomerulosclerosis. Am J Physiol Renal Physiol. 2008 ; 294: F801 - F811.
-
(2008)
Am J Physiol Renal Physiol
, vol.294
-
-
Krämer, S.1
Kron, S.2
Wang-Rosenke, Y.3
-
121
-
-
33847618799
-
Albumin activation of NAD(P)H oxidase activity is mediated via Rac1 in proximal tubule cells
-
Whaley-Connell AT, Morris EM, Rehmer N., et al. Albumin activation of NAD(P)H oxidase activity is mediated via Rac1 in proximal tubule cells. Am J Nephrol. 2007 ; 27: 15-23.
-
(2007)
Am J Nephrol
, vol.27
, pp. 15-23
-
-
Whaley-Connell, A.T.1
Morris, E.M.2
Rehmer, N.3
-
122
-
-
38349120435
-
Rosuvastatin improves basal nitric oxide activity of the renal vasculature in patients with hypercholesterolemia
-
Ott C., Schlaich MP, Schmidt BM, Titze SI, Schaufele T., Schmieder RE Rosuvastatin improves basal nitric oxide activity of the renal vasculature in patients with hypercholesterolemia. Atherosclerosis. 2007 ; 196: 704-711.
-
(2007)
Atherosclerosis
, vol.196
, pp. 704-711
-
-
Ott, C.1
Schlaich, M.P.2
Schmidt, B.M.3
Titze, S.I.4
Schaufele, T.5
Schmieder, R.E.6
-
123
-
-
33646095764
-
An overview of statin-associated proteinuria
-
Tiwari A. An overview of statin-associated proteinuria. Drug Discov Today. 2006 ; 11: 458-464.
-
(2006)
Drug Discov Today
, vol.11
, pp. 458-464
-
-
Tiwari, A.1
-
124
-
-
35549004107
-
Effects of rosuvastatin on glomerular capillary size-selectivity function in rats with renal mass ablation
-
Corna D SF, Cattaneo D., Carrara F., et al. Effects of rosuvastatin on glomerular capillary size-selectivity function in rats with renal mass ablation. Am J Nephrol. 2007 ; 27: 630-638.
-
(2007)
Am J Nephrol
, vol.27
, pp. 630-638
-
-
Corna, D.S.F.1
Cattaneo, D.2
Carrara, F.3
-
125
-
-
4344667844
-
Inhibitors of 3-hydroxy-3-methylglutaryl-CoA reductase reduce receptor-mediated endocytosis in opossum kidney cells
-
Sidaway JE, Davidson RG, McTaggart F., et al. Inhibitors of 3-hydroxy-3-methylglutaryl-CoA reductase reduce receptor-mediated endocytosis in opossum kidney cells. J Am Soc Nephrol. 2004 ; 15: 2258-2265.
-
(2004)
J Am Soc Nephrol
, vol.15
, pp. 2258-2265
-
-
Sidaway, J.E.1
Davidson, R.G.2
McTaggart, F.3
-
126
-
-
4344566156
-
Inhibitors of HMG-CoA reductase reduce receptor-mediated endocytosis in human kidney proximal tubular cells
-
Verhulst A., D'Haese PC, De Broe ME Inhibitors of HMG-CoA reductase reduce receptor-mediated endocytosis in human kidney proximal tubular cells. J Am Soc Nephrol. 2004 ; 15: 2249-2257.
-
(2004)
J Am Soc Nephrol
, vol.15
, pp. 2249-2257
-
-
Verhulst, A.1
D'Haese, P.C.2
De Broe, M.E.3
-
127
-
-
33745727522
-
Rosuvastatin, a new HMG-CoA reductase inhibitor, reduces the colonic inflammatory response in dextran sulfate sodium-induced colitis in mice
-
Naito Y., Katada K., Takagi T., et al. Rosuvastatin, a new HMG-CoA reductase inhibitor, reduces the colonic inflammatory response in dextran sulfate sodium-induced colitis in mice. Int J Mol Med. 2006 ; 17: 997-1004.
-
(2006)
Int J Mol Med
, vol.17
, pp. 997-1004
-
-
Naito, Y.1
Katada, K.2
Takagi, T.3
-
128
-
-
33646465740
-
Rosuvastatin reduces rat intestinal ischemia-reperfusion injury associated with the preservation of endothelial nitric oxide synthase protein
-
Naito Y., Katada K., Takagi T., et al. Rosuvastatin reduces rat intestinal ischemia-reperfusion injury associated with the preservation of endothelial nitric oxide synthase protein. World J Gastroenterol. 2006 ; 12: 2024-2030.
-
(2006)
World J Gastroenterol
, vol.12
, pp. 2024-2030
-
-
Naito, Y.1
Katada, K.2
Takagi, T.3
-
129
-
-
28344436469
-
Rosuvastatin as a novel treatment of non-alcoholic fatty liver disease in hyperlipidemic patients
-
Antonopoulos S., Mikros S., Mylonopoulou M., Kokkoris S., Giannoulis G. Rosuvastatin as a novel treatment of non-alcoholic fatty liver disease in hyperlipidemic patients. Atherosclerosis. 2006 ; 184: 233-234.
-
(2006)
Atherosclerosis
, vol.184
, pp. 233-234
-
-
Antonopoulos, S.1
Mikros, S.2
Mylonopoulou, M.3
Kokkoris, S.4
Giannoulis, G.5
-
130
-
-
25444500664
-
Rosuvastatin: A risk-benefit assessment for intensive lipid lowering
-
Ferdinand KC Rosuvastatin: a risk-benefit assessment for intensive lipid lowering. Expert Opin Pharmacother. 2005 ; 6: 1897-1910.
-
(2005)
Expert Opin Pharmacother
, vol.6
, pp. 1897-1910
-
-
Ferdinand, K.C.1
|