Active site of Escherichia coli DNA photolyase: Asn378 is crucial both for stabilizing the neutral flavin radical cofactor and for DNA repair

Biochemistry

Volumn 47, Issue 33, 2008, Pages 8736-8743

  Xu, Lei ^a,b   Mu, Wanmeng ^a,c   Ding, Yanwei ^d   Luo, Zhaofeng ^a   Han, Qingkai ^a   Bi, Fuyong ^b   Wang, Yuzhen ^a   Song, Qinhua ^a  

^a UNIVERSITY OF SCIENCE AND TECHNOLOGY OF CHINA   (China)

^b WANNAN MEDICAL COLLEGE   (China)

^c JIANGNAN UNIVERSITY   (China)

^d UNIVERSITY OF SCIENCE AND TECHNOLOGY OF CHINA   (China)

Author keywords

[No Author keywords available]

Indexed keywords

BUTANE; ELECTRON TRANSITIONS; ENZYME ACTIVITY; ESCHERICHIA COLI; FOOD ADDITIVES; FREE RADICAL REACTIONS; GENES; MAINTENANCE; NUCLEIC ACIDS; ORGANIC ACIDS; REPAIR;

ACTIVE SITES; CATALYTIC ACTIVITIES; COFACTOR; CYCLOBUTANE; DNA PHOTOLYASE; DNA-REPAIR; PHOTO-INDUCED ELECTRON TRANSFER;

DNA;

ACRIFLAVINE; ASPARAGINE; CYCLOBUTANE PYRIMIDINE DIMER; DEOXYRIBODIPYRIMIDINE PHOTOLYASE; DNA; FLAVINE ADENINE NUCLEOTIDE; PYRIMIDINE DERIVATIVE; SERINE;

ARTICLE; CATALYSIS; CONTROLLED STUDY; DNA REPAIR; ESCHERICHIA COLI; MUTANT; NONHUMAN; PRIORITY JOURNAL; PURIFICATION;

ASPARAGINE; BINDING SITES; DEOXYRIBODIPYRIMIDINE PHOTO-LYASE; DNA DAMAGE; DNA REPAIR; DNA, BACTERIAL; ESCHERICHIA COLI; FLAVINS; MUTATION; PROTEIN CONFORMATION;

ESCHERICHIA COLI;

EID: 49749112845     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi800391j     Document Type: Article

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