Immunohistochemical increase in cyclooxygenase-2 without apoptosis in different brain areas of subchronic nicotine- and D-amphetamine-treated rats

Journal of Neural Transmission

Volumn 115, Issue 8, 2008, Pages 1093-1108

  Toledano, A ^a   Alvarez M I ^a   Caballero, I ^b   Carmona, P ^c   De Miguel, E ^b  

^a INSTITUTO CAJAL   (Spain)

^b HOSPITAL UNIVERSITARIO LA PAZ   (Spain)

^c INSTITUTO DE ESTRUCTURA DE LA MATERIA   (Spain)

Author keywords

Brain; Cyclooxygenase 2; D(+)amphetamine; Immunochemistry; Immunohistochemistry; Nicotine; Nicotinic treatments; Oxidative stress

Indexed keywords

AMPHETAMINE; CYCLOOXYGENASE 2; NICOTINE; NICOTINE TARTRATE; NICOTINIC AGENT;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BRAIN CORTEX; CINGULATE GYRUS; COGNITION; CONTROLLED STUDY; DENTATE GYRUS; ECTORHINAL CORTEX; ENZYME ACTIVATION; FRONTAL CORTEX; HIPPOCAMPUS; IMMUNOHISTOCHEMISTRY; MALE; NERVE CELL NECROSIS; NERVE CELL PLASTICITY; NERVE DEGENERATION; NONHUMAN; PARIETAL LOBE; PRIORITY JOURNAL; RAT; SOMATOSENSORY CORTEX; TOBACCO DEPENDENCE; WESTERN BLOTTING;

ANIMALS; APOPTOSIS; BLOTTING, WESTERN; BRAIN; CENTRAL NERVOUS SYSTEM STIMULANTS; CEREBELLAR CORTEX; CYCLOOXYGENASE 2; DEXTROAMPHETAMINE; FREE RADICALS; FRONTAL LOBE; HIPPOCAMPUS; IMMUNOHISTOCHEMISTRY; LIPID PEROXIDATION; MALE; NEURONS; NICOTINE; NICOTINIC AGONISTS; RATS; RATS, WISTAR;

EID: 49749110433     PISSN: 03009564     EISSN: 14351463     Source Type: Journal    
DOI: 10.1007/s00702-008-0040-9     Document Type: Article

References (74)

1. EX Albuquerque EF Pereira A Mike HM Eisenberg A Maelicke M Alkondon 2000 Neuronal nicotinic receptors in synaptic functions in humans and rats: physiological and clinical relevance Behav Brain Res 113 131 141
2. KI Andersson A Savonenko S Vidensky JJ Goellner Y Zhang A Shaffer WE Kaufmann PF Worley P Isakson AL Markowska 2001 Age-dependent cognitive deficits and neuronal apoptosis in cyclooxygenase-2 transgenic mice J Neurosci 21 8198 8209
3. DM Barch CS Carter 2005 Amphetamine improves cognitive function in medicated individuals with schizophrenia and in healthy volunteers Schizophr Res 77 43 58
4. MM Bradford 1976 A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding Anal Biochem 72 248 254
5. CD Breder D Dewitt RP Kraig 1995 Characterization of inducible cyclooxygenase in rat brain J Comp Neurol 355 296 315
6. RW Brown B Kolb 2001 Nicotine sensitization increases dendritic length and spine density in the nucleus accumbens and cingulate cortex Brain Res 899 94 100
7. J Carlson K Noguchi G Ellison 2001 Nicotine produces selective degeneration in the medial habenula and fasciculus retroflexus Brain Res 906 127 134
8. YC Chang CH Tsai SH Yang CM Liu MY Chou 2003 Induction of cyclooxygenase-2 mRNA and protein expression in human gingival fibroblasts stimulated with nicotine J Periodontal Res 38 5 496 501
9. YW Chang R Jakobi A McGinty M Foschi MJ Dunn A Sorokin 2000 Cyclooxygenase 2 promotes cell survival by stimulation of dynein light chain expression and inhibition of neuronal nitric oxide synthase activity Mol Cell Biol 20 8571 8579
10. JS Choi HY Kim MH Chun JW Chung MY Lee 2006 Differential regulation of cycloxygenase-2 in the rat hippocampus after cerebral isquemia and ischemic tolerance Neurosci Let 393 231 236
11. SH Choi R Langenbach F Bosetti 2006 Cyclooxygenase-1 and -2 enzymes differentially regulate the brain upstream NF-kappa B pathway and downstream enzymes involved in prostaglandin biosynthesis J Neurochem 98 801 811
12. ZZ Chong F Li K Maiese 2005 Oxidative stress in the brain: novel cellular targets that govern survival during neurodegenerative disease Prog Neurobiol 75 207 246
13. C Consilvio AM Vicent EL Feldman 2004 Neuroinflammation, COX-2, and ALS. A dual role? Exp Neurol 187 1 10
14. JG Cui H Kuroda NV Chandrasekharan RP Pelaez DL Simmons NG Bazan WJ Lukiw 2004 Cyclooxygenase-3 gene expression in Alzheimer hippocampus and in stressed human neural cells Neurochem Res 29 1731 1737
15. JA Dani D Ji FM Zhou 2001 Synaptic plasticity and nicotine addiction Neuron 31 349 352
16. PK Dash SA Mach AN Moore 2000 Regional expression and role cyclooxygenase-2 following experimental traumatic brain injury J Neurotrauma 17 69 81
17. C Davidson AJ Gow TH Lee EH Ellinwood 2001 Methamphetamine neurotoxicity: necrotic and apoptotic mechanisms and relevance to human abuse and treatment Brain Res Rev 36 1 22
18. R De Simone MA Ajmone-Cat D Carnevale L Minghetti 2005 Activation of alpha7 nicotinic acetylcholine receptor by nicotine selectively up-regulates cyclooxygenase-2 and prostaglandin E2 in rat microglial cultures J Neuroinflammation 25 4
19. MH Deininger K Bekure-Nemariam K Trautmann M Morgalla R Meyermann HJ Schlucsener 2003 Cyclooxygenase-1 and -2 in brains of patients who died with sporadic Creutzfeldt-Jakob disease J Mol Neurosci 20 25 30
20. P Eikelenboom WA Van Gool 2004 Neuroinflammatory perspectives on the two faces of Alzheimer's disease J Neural Transm 111 281 294
21. RE Featherstone S Kapur PJ Fletcher 2007 The amphetamine-induced sensitized state as a model of schizophrenia Prog Neuropsychopharmacol Biol Psychiat 31 1556 1571
22. K Fujimi K Noda K Sasaki Y Wakisaka Y Tanizaki M Iida Y Kiyohara S Kanba T Iwaki 2007 Altered expression of COX-2 in subdivisions of the hippocampus during aging and in Alzheimer's disease: The Hisayama study Dement Geriatr Cogn Disord 23 423 431
23. LC Gahring K Persiyanov EL Days SW Rogers 2005 Age-related loss of neuronal nicotinic receptor expression in the aging mouse hippocampus corresponds with cyclooxygenase-2 and PPAR gamma expression and is altered by long-term NS398 administration J Neurobiol 62 453 468
24. MG Giovannini C Scali C Prosperi A Bellucci G Pepeu F Casamenti 2003 Experimental brain inflammation and neurodegenerations as model of Alzheimer's disease: protective effects of selective COX-2 inhibitors Int J Immunopathol Pharmacol 16 S31 S40
25. Gunne LM (1977) Effects of amphetamine in humans. In: Martin WR (eds) Drug addiction II: amphetamine, psychotogen, and marihuana dependence. Springerg, Berlin, pp 247-275
26. R Gutala J Wang YY Hwang R Haq MD Li 2006 Nicotine modulates expression of amyloid precursor protein and amyloid precursor-like protein 2 in mouse brain and in SH-SY5Y neuroblastoma cells Brain Res 1093 12 19
27. JA Harvey 1987 Behavioral pharmacology of central nervous system stimulants Neuropharmacology 26 887 892
28. EA Hassoun M Al-Ghafri A Abushaban 2003 The role of antioxidant enzymes in TCDD-induced oxidative stress in various brain regions of rats after subchronic exposure Free Radic Biol Med 35 1028 1036
29. MV Hejmadi F Dajas-Bailador SM Barns B Jones S Wonnacott 2003 Neuroprotection by nicotine against hypoxia-induced apoptosis in cortical cultures involves activation of multiple nicotinic acetylcholine receptor subtypes Mol Cell Neurosci 24 779 786
30. SJ Hewett SC Bell JA Hewett 2006 Contributions of cyclooxygenase-2 to neuroplasticity and neuropathology of the central nervous system Pharmacol Ther 112 335 357
31. JJ Hoozemans AJ Rozemuller R Veerhuis P Eikelenboom 2001 Immunological aspects of Alzheimeŕs disease: therapeutic implication Bio Drug 15 325 337
32. JJ Hoozemans ES van Haastert R Veerhuis T Arendt W Scheper P Eikelenboom AJ Rozemuller 2005 Maximal COX-2 and ppRb expression in neurons occurs during early Braak stages prior to the maximal activation of astrocytes and microglia in Alzheimer's disease J Neuroinflammation 21;2 27
33. JJ Hoozemans R Veerhuis JM Rozemuller P Eikelenboom 2006 Neuroinflammation and regeneration in the early stages of Alzheimer's disease pathology Int J Dev Neurosci 24 157 165
34. SD Iversen 1998 The pharmacology of memory C R Acad Sci III 321 209 215
35. RR Jonnala JJ Buccafusco 2001 Relationship between the increased cell surface alpha7 nicotinic receptor expression and neuroprotection induced by several nicotinic receptor agonists J Neurosci Res 66 565 572
36. WE Kaufman KI Andreasson PC Isakson PF Worley 1997 Cyclooxygenases and the central nervous system Prostaglandins 54 601 624
37. T Kihara S Shimohama M Urushitani H Sawada J Kimura T Kume T Maeda A Akaike 1997 Nicotine receptor stimulation protects neurons against beta-amyloid toxicity Ann Neurol 42 159 163
38. P Kovacic AL Cooksy 2005 Unifying mechanism for toxicity and addiction by abused drugs: electron transfer and reactive oxygen species Med Hypotheses 64 357 366
39. T Kunz N Marklund L Hillered EH Oliw 2002 Cyclooxygenase-2, prostaglandin synthases, and prostaglandin H2 metabolism in traumatic brain injury in the rat J Neurotrauma 19 1051 1064
40. C Le Magueresse V Safiulina JP Changeux E Cherubini 2006 Nicotinic modulation of network and synaptic transmission in the immature hippocampus investigated with genetically modified mice J Physiol 576 533 546
41. ED Levin BB Simon 1998 Nicotinic acetylcholine involvement in cognitive function in animals Psychopharmacology 138 217 230
42. ED Levin A Bradley N Addy N Sigurani 2002 Hippocampal alpha 7 and alpha 4 beta 2 nicotinic receptors and working memory Neuroscience 109 757 765
43. ED Levin FJ McClernon AH Rezvani 2006 Nicotinic effects on cognitive function: behavioral characterization, pharmacological specification, and anatomic localization Psychopharmacology (Berl) 184 523 539
44. Y Li RL Papke YL He WJ Millard EM Meyer 1999 Characterization of the neuroprotective and toxic effects of alpha-7 nicotinic receptor activation in PC12 cells Brain Res 830 218 225
45. L Li K Prabhakaran Y Shou JL Borowitz GE Isom 2002 Oxidative stress and cyclooxygenase-2 induction cyanide-induced apoptosis of cortical cells Toxicol Appl Pharmacol 185 55 63
46. Q Liu B Zhao 2004 Nicotine attenuates beta-amyloid peptide-induced neurotoxicity, free radical and calcium accumulation in hippocampal neuron culturs Br J Pharmacol 141 746 754
47. R Martínez-Murillo R Martínez-Rodríguez G Arenas L Franic A Hernández F Estrada 1985 Succinic and malic dehydrogenase histochemical activities in cerebral, cerebellar and neostriatum sections incubated in presence of d-amphetamine Acta Neuropathol 67 81 85
48. R Martínez-Rodríguez R Martínez-Murillo 1984 In vitro d-amphetamine action on oxido-reductase activity of several rat nervous centres Acta Histochem 74 85 90
49. R Martínez-Rodríguez A Toledano MI Álvarez L Turégano O Colman P Rosés I de Gómez Segura E De Miguel 2003 Chronic nicotine administration increases NGF-like immunoreactivity in frontoparietal cerebral cortex J Neurosci Res 73 708 716
50. A Mazurov T Hauser CH Miller 2006 Selective alpha7 nicotinic acetylcholine receptor ligands Curr Med Chem 13 1567 1584
51. S Miettinen FR Fusco J Yrjanheikki R Keinanen T Hirvonen R Roivainen M Narhi T Hokfelt J Koistinaho 1997 Spreading depression and focal brain ischemia induce cyclooxygenase-2 in cortical neurons through N-methyl-d-aspartic acid-receptors and phospholipase A2 Proc Natl Acad Sci USA 94 6500 6505
52. L Minghetti MA Ajmone-Cat MA De Berardinis R De Simone 2005 Microglial activation in chronic neurodegenerative diseases: roles of apoptotic neurons and chronic stimulation Brain Res Brain Res Rev 48 251 256
53. I Morita 2002 Distinct functions of COX-1 and COX-2 Prostaglandins Other Lipid Mediat 68-69 165 175
54. MT Oliveira AC Rego TRA Macedo CR Oliveira 2003 Drugs of abuse induce apoptotic features in PC12 cells Ann N Y Acad Sci 1010 667 670
55. TJ Ornstein JL Iddon AM Baldacchino BJ Sahakian M London BJ Everitt TW Robbins 2000 Profiles of cognitive dysfunction in chronic amphetamine and heroin abusers Neuropsychopharmacol 23 113 126
56. GM Pasinetti PS Aisen 1998 Cyclooxygenase-2 expression is increased in frontal cortex of Alzheimer's disease brain Neurosci 87 319 324
57. Paxinos G, Watson C (1998) The rat brain in stereotaxic coordinates, 4th edn. Academic press. San Diego
58. JW Phillis LA Horrocks AA Farooqui 2006 Cyclooxygenases, lipoxygenases, and epoxygenases in CNS: their role and involvement in neurological disorders Brain Res Rev 52 201 243
59. TA Rondini SP Baddini LF Sousa JC Bittencourt CF Elias 2004 Hypothalamic cocaine- and amphetamine-regulated transcript neurons project to areas expressing gonadotropin releasing hormone immunoreactivity and to the anteroventral periventricular nucleus in male and female rats Neuroscience 125 735 748
60. MD Rosato-Siri A Cattaneo E Cherubini 2006 Nicotine-induced enhancement of synaptic plasticity at CA3-CA1 synapses requires GABAergic interneurons in adult anti NGF mice J Physiol 576 361 377
61. BM Ross RJ Brooks KS Kalasinsky SP Vorce M Seeman PJ Fletcher SD Turenns 2002 Cyclooxygenase inhibitor modulation of dopamine-related behaviours Eur J Pharmacol 23 141 151
62. LJ Ryan JC Linder ME Martone PM Groves 1990 Histological and ultrastructural evidence that d-amphetamine causes degeneration in the neostriatum and frontal cortex of rats Brain Res 518 66 77
63. JC Schiltz PE Sawchenko 2002 Distinct brain vascular cell types manifest inducible cyclooxygenase expression as a function of the strength and nature of immune insults J Neurosci 22 5606 5618
64. M Sharifzadeh M Tavasoli N Naghdi A Ghanbari M Amini A Roghani 2005 Post-training intrahippocampal infusion of nicotine prevents spatial memory retention deficits induced by the cyclo-oxygenase-2-specific inhibitor celecoxib in rats J Neurochem 95 1078 1090
65. F Shen GE Meredith TC Napier 2006 Amphetamine-induced place preference and conditioned motor sensitization requires activation of tyrosine kinase receptors in the hippocampus J Neurosci 26 11041 11051
66. SY Shu G Ju LZ Fan 1988 The glucose oxidase-DAB-nickel method in peroxidase histochemistry of the nervous system Neurosci Lett 85 169 171
67. G Stumm J Schlegel T Schafer C Wurz HD Mennel JC Krieg H Vedder 1999 Amphetamines induce apoptosis and regulation of bcl-x splice variants in neocortical neurons FASEB J 13 1065 1072
68. DM Thomas DM Kuhn 2005 Cyclooxygenase-2 is an obligatory factor in methamphetamine-induced neurotoxicity J Pharmacol Exp Ther 313 870 876
69. A Toledano MI Álvarez L Rivas C Lacruz R Martínez- Rodríguez 1999 Amyloid precursor proteins in the cerebellar cortex of Alzheimer's disease patients devoid of cerebellar beta-amyloid deposits: immunocytochemical study of five cases J Neural Transm 106 1151 1169
70. L Turégano R Martínez-Rodríguez MI Álvarez RR Gragera I de Gómez Segura E De Miguel A Toledano 2001 Histochemical study of acute and chronic intraperitoneal effects on several glycolitic and Krebs cycle dehydrogenase activities in the frontoparietal cortex and subcortical nuclei of the rat brain J Neurosci Res 64 626 635
71. B Weiss VG Laties 1962 Enhancement of human performance by caffeine and the amphetamines Pharmacol Rev 14 1 36
72. S Wonnacott N Sidhpura DJ Balfour 2005 Nicotine: from molecular mechanisms to behaviour Curr Opin Pharmacol 5 53 59
73. Wood PL (2003) The cerebellum in AD. A case for arrested neuroinflammation? In: Wood PL (eds) Neuroinflammation. Mechanism and management. 2nd edn. Humana Press, Totova, pp 295-300
74. K Yamagata KI Andreasson WE Kaufmann CA Barnes PF Worley 1993 Expression of a mitogen-inducible cyclooxygenase in brain neurons: regulation by synaptic activity and glucocorticoids Neuron 11 371 386