Ethanol enhances tau accumulation in neuroblastoma cells that inducibly express tau

Neuroscience Letters

Volumn 443, Issue 2, 2008, Pages 67-71

  Gendron, Tania F ^a   McCartney, Sharon ^a   Causevic, Ena ^a   Ko, Li wen ^a   Yen, Shu Hui ^a  

^a MAYO CLINIC   (United States)

Author keywords

Calpain; Ethanol; Human neuroblastoma cells; Microtubule associated protein tau

Indexed keywords

ALCOHOL; CALPAIN 1; CATHEPSIN B; CATHEPSIN D; CHYMOTRYPSIN; MESSENGER RNA; SHORT HAIRPIN RNA; TAU PROTEIN; TETRACYCLINE;

ARTICLE; CELL DEATH; CELL VIABILITY; HUMAN; HUMAN CELL; NEUROBLASTOMA CELL; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN FUNCTION;

CALPAIN; CELL LINE, TUMOR; CENTRAL NERVOUS SYSTEM DEPRESSANTS; ETHANOL; GENE EXPRESSION; HUMANS; NEUROBLASTOMA; NEURONS; POLYMERASE CHAIN REACTION; RNA, MESSENGER; TAU PROTEINS;

EID: 49749102766     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neulet.2008.07.052     Document Type: Article

References (35)

1. Ahluwalia B., Ahmad S., Adeyiga O., Wesley B., and Rajguru S. Low levels of ethanol stimulate and high levels decrease phosphorylation in microtubule-associated proteins in rat brain: an in vitro study. Alcohol Alcohol. 35 (2000) 452-457
2. Amadoro G., Ciotti M.T., Costanzi M., Cestari V., Calissano P., and Canu N. NMDA receptor mediates tau-induced neurotoxicity by calpain and ERK/MAPK activation. Proc. Natl. Acad. Sci. U.S.A. 103 (2006) 2892-2897
3. Chakraborty G., Saito M., Mao R.F., Wang R., Vadasz C., and Saito M. Lithium blocks ethanol-induced modulation of protein kinases in the developing brain. Biochem. Biophys. Res. Commun. 367 (2008) 597-602
4. Cullen K.M., and Halliday G.M. Mechanisms of cell death in cholinergic basal forebrain neurons in chronic alcoholics. Metab. Brain Dis. 10 (1995) 81-91
5. DePetrillo P.B. Calcium-activated neutral protease activity is decreased in PC12 cells after ethanol exposure. J. Neurochem. 68 (1997) 1863-1869
6. Donohue Jr. T.M. The ubiquitin-proteasome system and its role in ethanol-induced disorders. Addict. Biol. 7 (2002) 15-28
7. Elliott E., Tsvetkov P., and Ginzburg I. BAG-1 associates with Hsc70.Tau complex and regulates the proteasomal degradation of Tau protein. J. Biol. Chem. 282 (2007) 37276-37284
8. Feinstein S.C., and Wilson L. Inability of tau to properly regulate neuronal microtubule dynamics: a loss-of-function mechanism by which tau might mediate neuronal cell death. Biochim. Biophys. Acta 1739 (2005) 268-279
9. Gutala R., Wang J., Kadapakkam S., Hwang Y., Ticku M., and Li M.D. Microarray analysis of ethanol-treated cortical neurons reveals disruption of genes related to the ubiquitin-proteasome pathway and protein synthesis. Alcohol Clin. Exp. Res. 28 (2004) 1779-1788
10. Guttmann R.P., and Johnson G.V. Oxidative stress inhibits calpain activity in situ. J. Biol. Chem. 273 (1998) 13331-13338
11. Hamano T., Gendron T.F., Causevic E., Yen S.H., Lin W.L., Isidoro C., Deture M., and Ko L.W. Autophagic-lysosomal perturbation enhances tau aggregation in transfectants with induced wild-type tau expression. Eur. J. Neurosci. 22 (2008) 22
12. He D.Y., and Ron D. GDNF reverses ethanol-mediated increases in tyrosine hydroxylase immunoreactivity via altering the activity of HSP90. J. Biol. Chem. 14 (2008) 14
13. Johnson G.V. Tau phosphorylation and proteolysis: insights and perspectives. J. Alzheimers Dis. 9 (2006) 243-250
14. Johnson G.V., Jope R.S., and Binder L.I. Proteolysis of tau by calpain. Biochem. Biophys. Res. Commun. 163 (1989) 1505-1511
15. Kannarkat G.T., Tuma D.J., and Tuma P.L. Microtubules are more stable and more highly acetylated in ethanol-treated hepatic cells. J. Hepatol. 44 (2006) 963-970
16. Kharbanda K.K., McVicker D.L., Zetterman R.K., and Donohue Jr. T.M. Ethanol consumption reduces the proteolytic capacity and protease activities of hepatic lysosomes. Biochim. Biophys. Acta 1245 (1995) 421-429
17. Ko L.W., Rush T., Sahara N., Kersh J.S., Easson C., Deture M., Lin W.L., Connor Y.D., and Yen S.H. Assembly of filamentous tau aggregates in human neuronal cells. J. Alzheimers Dis. 6 (2004) 605-622 (discussion 673-681)
18. Mercken M., Grynspan F., and Nixon R.A. Differential sensitivity to proteolysis by brain calpain of adult human tau, fetal human tau and PHF-tau. FEBS Lett. 368 (1995) 10-14
19. Noraberg J., and Zimmer J. Ethanol induces MAP2 changes in organotypic hippocampal slice cultures. Neuroreport 9 (1998) 3177-3182
20. Panda D., Samuel J.C., Massie M., Feinstein S.C., and Wilson L. Differential regulation of microtubule dynamics by three- and four-repeat tau: implications for the onset of neurodegenerative disease. Proc. Natl. Acad. Sci. U.S.A. 100 (2003) 9548-9553
21. Poso A.R., Surmacz C.A., and Mortimore G.E. Inhibition of intracellular protein degradation by ethanol in perfused rat liver. Biochem. J. 242 (1987) 459-464
22. Preisegger K.H., Zatloukal K., Spurej G., Riegelnegg D., and Denk H. Common epitopes of human and murine Mallory bodies and Lewy bodies as revealed by a neurofilament antibody. Lab. Invest. 66 (1992) 193-199
23. Probst A., Gotz J., Wiederhold K.H., Tolnay M., Mistl C., Jaton A.L., Hong M., Ishihara T., Lee V.M., Trojanowski J.Q., Jakes R., Crowther R.A., Spillantini M.G., Burki K., and Goedert M. Axonopathy and amyotrophy in mice transgenic for human four-repeat tau protein. Acta Neuropathol. 99 (2000) 469-481
24. Prock T.L., and Miranda R.C. Embryonic cerebral cortical progenitors are resistant to apoptosis, but increase expression of suicide receptor DISC-complex genes and suppress autophagy following ethanol exposure. Alcohol Clin. Exp. Res. 31 (2007) 694-703
25. Reiter-Funk C.K., and Dohrman D.P. Chronic ethanol exposure increases microtubule content in PC12 cells. BMC Neurosci. 6 (2005) 16
26. Shea T.B. Restriction of microM-calcium-requiring calpain activation to the plasma membrane in human neuroblastoma cells: evidence for regionalized influence of a calpain activator protein. J. Neurosci. Res. 48 (1997) 543-550
27. Spencer J.P., Rice-Evans C., and Williams R.J. Modulation of pro-survival Akt/protein kinase B and ERK1/2 signaling cascades by quercetin and its in vivo metabolites underlie their action on neuronal viability. J. Biol. Chem. 278 (2003) 34783-34793
28. Spittaels K., Van den Haute C., Van Dorpe J., Bruynseels K., Vandezande K., Laenen I., Geerts H., Mercken M., Sciot R., Van Lommel A., Loos R., and Van Leuven F. Prominent axonopathy in the brain and spinal cord of transgenic mice overexpressing four-repeat human tau protein. Am. J. Pathol. 155 (1999) 2153-2165
29. Sun A.Y., and Sun G.Y. Ethanol and oxidative mechanisms in the brain. J. Biomed. Sci. 8 (2001) 37-43
30. Tan S.E., Abel E.L., and Berman R.F. Brain MAP-2 phosphorylation is decreased following prenatal alcohol exposure in rats. Alcohol 10 (1993) 391-396
31. Thies E., and Mandelkow E.M. Missorting of tau in neurons causes degeneration of synapses that can be rescued by the kinase MARK2/Par-1. J. Neurosci. 27 (2007) 2896-2907
32. Whatley V.J., Brozowski S.J., Hadingham K.L., Whiting P.J., and Harris R.A. Microtubule depolymerization inhibits ethanol-induced enhancement of GABAA responses in stably transfected cells. J. Neurochem. 66 (1996) 1318-1321
33. Wittmann C.W., Wszolek M.F., Shulman J.M., Salvaterra P.M., Lewis J., Hutton M., and Feany M.B. Tauopathy in Drosophila: neurodegeneration without neurofibrillary tangles. Science 293 (2001) 711-714
34. Xie H.Q., and Johnson G.V. Calcineurin inhibition prevents calpain-mediated proteolysis of tau in differentiated PC12 cells. J. Neurosci. Res. 53 (1998) 153-164
35. Yen S., Easson C., Nacharaju P., Hutton M., and Yen S.H. FTDP-17 tau mutations decrease the susceptibility of tau to calpain I digestion. FEBS Lett. 461 (1999) 91-95