-
1
-
-
33644543761
-
Expanding insights of mitochondrial dysfunction in Parkinson's disease
-
Abou-Sleiman PM, et al. (2006) Expanding insights of mitochondrial dysfunction in Parkinson's disease. Nat Rev Neurosci 7:207-219.
-
(2006)
Nat Rev Neurosci
, vol.7
, pp. 207-219
-
-
Abou-Sleiman, P.M.1
-
2
-
-
2442668926
-
Hereditary early-onset Parkinson's disease caused by mutations in PINK1
-
Valente EM, et al. (2004) Hereditary early-onset Parkinson's disease caused by mutations in PINK1. Science 304:1120-1122.
-
(2004)
Science
, vol.304
, pp. 1120-1122
-
-
Valente, E.M.1
-
3
-
-
0032499264
-
Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism
-
Kitada T, et al. (1998) Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism. Nature 392:605-608.
-
(1998)
Nature
, vol.392
, pp. 605-608
-
-
Kitada, T.1
-
4
-
-
0037428241
-
Mutations in the DJ-1 gene associated with autosomal recessive early-onset parkinsonism
-
Bonifati V, et al. (2003) Mutations in the DJ-1 gene associated with autosomal recessive early-onset parkinsonism. Science 299:256-259.
-
(2003)
Science
, vol.299
, pp. 256-259
-
-
Bonifati, V.1
-
5
-
-
2942684871
-
The Parkinson's disease protein DJ-1 is neuroprotective due to cysteine-sulfinic acid-driven mitochondrial localization
-
Canet-Avilés RM, et al. (2004) The Parkinson's disease protein DJ-1 is neuroprotective due to cysteine-sulfinic acid-driven mitochondrial localization. Proc Natl Acad Sci USA 101:9103-9108.
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 9103-9108
-
-
Canet-Avilés, R.M.1
-
6
-
-
33750594065
-
Genetics of Parkinson's disease and parkinsonism
-
Hardy J, et al. (2006) Genetics of Parkinson's disease and parkinsonism. Ann Neurol 60:389-398.
-
(2006)
Ann Neurol
, vol.60
, pp. 389-398
-
-
Hardy, J.1
-
7
-
-
49649097747
-
Loss of PINK1 Causes mitochondrial functional defects and increased sensitivity to oxidative stress
-
Gautier CA, et al. (2008) Loss of PINK1 Causes mitochondrial functional defects and increased sensitivity to oxidative stress. Proc Natl Acad Sci USA 105:11364-11369.
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, pp. 11364-11369
-
-
Gautier, C.A.1
-
8
-
-
0033032999
-
Mitochondrial involvement in Parkinson's disease, Huntington's disease, hereditary spastic paraplegia and Friedreich's ataxia
-
Schapira AH (1999) Mitochondrial involvement in Parkinson's disease, Huntington's disease, hereditary spastic paraplegia and Friedreich's ataxia. Biochim Biophys Acta 1410:159-170.
-
(1999)
Biochim Biophys Acta
, vol.1410
, pp. 159-170
-
-
Schapira, A.H.1
-
9
-
-
2442504779
-
1-Methyl-4-phenylpyridinium-induced apoptosis in cerebellar granule neurons is mediated by transferrin receptor iron-dependent depletion of tetrahydrobiopterin and neuronal nitric-oxide synthase-derived superoxide
-
Shang T, et al. (2004) 1-Methyl-4-phenylpyridinium-induced apoptosis in cerebellar granule neurons is mediated by transferrin receptor iron-dependent depletion of tetrahydrobiopterin and neuronal nitric-oxide synthase-derived superoxide. J Biol Chem 279:19099-19112.
-
(2004)
J Biol Chem
, vol.279
, pp. 19099-19112
-
-
Shang, T.1
-
10
-
-
35548972027
-
DJ-1 gene deletion reveals that DJ-1 is an atypical peroxiredoxin-like peroxidase
-
Andres-Mateos E, et al. (2007) DJ-1 gene deletion reveals that DJ-1 is an atypical peroxiredoxin-like peroxidase. Proc Natl Acad Sci USA 104:14807-14812.
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, pp. 14807-14812
-
-
Andres-Mateos, E.1
-
11
-
-
33745589773
-
Drosophila pink1 is required for mitochondrial function and interacts genetically with Parkin
-
Clark IE, et al. (2006) Drosophila pink1 is required for mitochondrial function and interacts genetically with Parkin. Nature 441:1162-1165.
-
(2006)
Nature
, vol.441
, pp. 1162-1165
-
-
Clark, I.E.1
-
12
-
-
33745602748
-
Mitochondrial dysfunction in Drosophila PINK1 mutants is complemented by Parkin
-
Park J, et al. (2006) Mitochondrial dysfunction in Drosophila PINK1 mutants is complemented by Parkin. Nature 441:1157-1161.
-
(2006)
Nature
, vol.441
, pp. 1157-1161
-
-
Park, J.1
-
13
-
-
33746080412
-
Mitochondrial pathology and muscle and dopaminergic neuron degeneration caused by inactivation of Drosophila Pink1 is rescued by Parkin
-
Yang Y, et al. (2006) Mitochondrial pathology and muscle and dopaminergic neuron degeneration caused by inactivation of Drosophila Pink1 is rescued by Parkin. Proc Natl Acad Sci USA 103:10793-10798.
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, pp. 10793-10798
-
-
Yang, Y.1
-
14
-
-
39449088321
-
The PINK1/Parkin pathway regulates mitochondrial morphology
-
Poole AC, et al. (2008) The PINK1/Parkin pathway regulates mitochondrial morphology. Proc Natl Acad Sci USA 105:1638-1643.
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, pp. 1638-1643
-
-
Poole, A.C.1
-
15
-
-
36049038504
-
Loss-of-function of human PINK1 results in mitochondrial pathology and can be rescued by Parkin
-
Exner N, et al. (2007) Loss-of-function of human PINK1 results in mitochondrial pathology and can be rescued by Parkin. J Neurosci 27:12413-12418.
-
(2007)
J Neurosci
, vol.27
, pp. 12413-12418
-
-
Exner, N.1
-
16
-
-
44349195101
-
Pink1 regulates mitochondrial dynamics through interaction with the fission/ fusion machinery
-
Yang Y, et al. (2008) Pink1 regulates mitochondrial dynamics through interaction with the fission/ fusion machinery. Proc Natl Acad Sci USA 105:7070-7075.
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, pp. 7070-7075
-
-
Yang, Y.1
-
17
-
-
45749117188
-
Mitochondrial fragmentation in neurodegeneration
-
Knott A, et al. (2008) Mitochondrial fragmentation in neurodegeneration. Nat Rev Neurosci 9:505-518.
-
(2008)
Nat Rev Neurosci
, vol.9
, pp. 505-518
-
-
Knott, A.1
-
18
-
-
33750018371
-
Detrimental deletions: Mitochondria, aging and Parkinson's disease
-
Biskup S, Moore DJ (2006) Detrimental deletions: mitochondria, aging and Parkinson's disease. BioEssays 28(10):963-967.
-
(2006)
BioEssays
, vol.28
, Issue.10
, pp. 963-967
-
-
Biskup, S.1
Moore, D.J.2
-
19
-
-
49349087497
-
PINK1 is necessary for long term survival and mitochondrial function in human dopaminergic neurons
-
Wood-Kaczmar A, et al. (2008) PINK1 is necessary for long term survival and mitochondrial function in human dopaminergic neurons. PLoS ONE 3:e2455.
-
(2008)
PLoS ONE
, vol.3
-
-
Wood-Kaczmar, A.1
-
20
-
-
34547127902
-
PINK1 protects against oxidative stress by phosphorylating mitochondrial chaperone TRAP1
-
Pridgeon JW, et al. (2008) PINK1 protects against oxidative stress by phosphorylating mitochondrial chaperone TRAP1. PLoS Biol 5:1494-1503.
-
(2008)
PLoS Biol
, vol.5
, pp. 1494-1503
-
-
Pridgeon, J.W.1
-
21
-
-
35748935851
-
The mitochondrial protease HtrA2 is regulated by Parkinson's disease-associated kinase PINK1
-
Plun-Favreau H, et al. (2007) The mitochondrial protease HtrA2 is regulated by Parkinson's disease-associated kinase PINK1. Nat Cell Biol 9:1243-1252.
-
(2007)
Nat Cell Biol
, vol.9
, pp. 1243-1252
-
-
Plun-Favreau, H.1
-
22
-
-
45249112594
-
Characterization of PINK1 processing, stability, and subcellular localization
-
Lin W, Kang UJ (2008) Characterization of PINK1 processing, stability, and subcellular localization. J Neurochem 106:464-474.
-
(2008)
J Neurochem
, vol.106
, pp. 464-474
-
-
Lin, W.1
Kang, U.J.2
-
23
-
-
34249735817
-
Akt attenuation of the serine protease activity of HtrA2/Omi through phosphorylation of serine 212
-
Yang L, et al. (2007) Akt attenuation of the serine protease activity of HtrA2/Omi through phosphorylation of serine 212. J Biol Chem 282:10981-10987.
-
(2007)
J Biol Chem
, vol.282
, pp. 10981-10987
-
-
Yang, L.1
|