Enantioseparation of (R,S)-ketoprofen using Candida antarctica lipase B in an enzymatic membrane reactor

Journal of Separation Science

Volumn 31, Issue 13, 2008, Pages 2476-2485

  Ong, Ai Lien ^a   Kamaruddin, Azlina Harun ^a   Bhatia, Subhash ^a   Aboul Enein, Hassan Y ^b  

^a SCHOOL OF CHEMICAL ENGINEERING   (Malaysia)

^b NATIONAL RESEARCH CENTRE   (Egypt)

Author keywords

Chiral drug; Enantioseparation; Enzymatic membrane reactor; Ketoprofen; Lipase

Indexed keywords

BATCH REACTORS; BIOREACTORS; CONCENTRATION (PROCESS); COST EFFECTIVENESS; ELECTRONIC MEDICAL EQUIPMENT; ENZYME IMMOBILIZATION; ENZYMES; FOOD ADDITIVES; ISOMERS; MEMBRANES; RATE CONSTANTS; SUBSTRATES;

CANDIDA ANTARCTICA LIPASE B; CATALYTIC BEHAVIOUR; CHIRAL DRUG; COMPARATIVE STUDIES; ENANTIOSEPARATION; ENZYMATIC MEMBRANE REACTOR; ENZYME LOADS; FLOW-RATE; KETOPROFEN; LIPASE; MOLAR RATIOS; PROCESS PARAMETERS; REACTION TEMPERATURES; SOLUTION PH; SUBSTRATE CONCENTRATIONS; THERMAL STABILITY;

ELECTRIC RELAYS;

KETOPROFEN; LIPASE B;

ARTICLE; BATCH REACTOR; BIOCATALYST; CANDIDA ANTARCTICA; CATALYSIS; CONTROLLED STUDY; DRUG DETERMINATION; DRUG STRUCTURE; ENANTIOSELECTIVITY; ENZYME IMMOBILIZATION; ENZYME ISOLATION; ENZYME MEMBRANE BIOREACTOR; ENZYME SUBSTRATE; FLOW RATE; INTERMETHOD COMPARISON; NONHUMAN; PRIORITY JOURNAL; THERMOSTABILITY;

1-BUTANOL; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; CANDIDA; CHEMICAL ENGINEERING; CHEMISTRY, ANALYTICAL; ENZYMES, IMMOBILIZED; ESTERIFICATION; HYDROGEN-ION CONCENTRATION; KETOPROFEN; LIPASE; STEREOISOMERISM; TEMPERATURE;

CANDIDA ANTARCTICA;

EID: 49649086941     PISSN: 16159306     EISSN: 16159314     Source Type: Journal    
DOI: 10.1002/jssc.200800086     Document Type: Article

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