Myometrial mechanoadaptation during pregnancy: Implications for smooth muscle plasticity and remodelling

Journal of Cellular and Molecular Medicine

Volumn 12, Issue 4, 2008, Pages 1360-1373

  Wu, X ^a   Morgan, K G ^b   Jones, C J ^a   Tribe, R M ^c   Taggart, M J ^d  

^a UNIVERSITY OF MANCHESTER   (United Kingdom)

^b BOSTON UNIVERSITY   (United States)

^c KING'S COLLEGE LONDON   (United Kingdom)

^d NEWCASTLE UNIVERSITY   (United Kingdom)

Author keywords

Dense plaques; Mechanotransduction; Myometrium; Smooth muscle plasticity; Smooth muscle remodelling

Indexed keywords

ACTIN; PLACENTA PROTEIN;

ADAPTATION; ANIMAL; ARTICLE; BIOLOGICAL MODEL; BIOMECHANICS; BODY WEIGHT; BREEDING; ESTRUS CYCLE; FEMALE; GROWTH, DEVELOPMENT AND AGING; METABOLISM; MOUSE; MYOMETRIUM; ORGAN SIZE; PHYSIOLOGY; PREGNANCY; ULTRASTRUCTURE; UTERUS;

ACTINS; ADAPTATION, PHYSIOLOGICAL; ANIMALS; BIOMECHANICS; BODY WEIGHT; ESTROUS CYCLE; FEMALE; MICE; MODELS, BIOLOGICAL; MYOMETRIUM; ORGAN SIZE; PREGNANCY; PREGNANCY PROTEINS; PREGNANCY, ANIMAL; UTERUS;

MUS;

EID: 49549121652     PISSN: 15821838     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1582-4934.2008.00306.x     Document Type: Article

References (46)

1. Katsumi A, Orr A, Tzima WE, Schwartz MA. Integrins in mechanotransduction. J Biol Chem. 2004 279 : 12001 4.
2. Ernstrom GG, Chalfie M. Genetics of sensory mechanotransduction. Ann Rev Genet. 2002 36 : 411 53.
3. Huang S, Ingber DE. The structural and mechanical complexity of cell-growth control. Nat Cell Biol. 1999 1 : E131 8.
4. Schwartz MA, Assoian RK. Integrins and cell proliferation: regulation of cyclin-dependent kinases via cytoplasmic signaling pathways. J Cell Sci. 2001 114 : 2553 60.
5. Gunst SJ, Tang DD, Opazo Saez A. Cytoskeletal remodeling of the airway smooth muscle cell: a mechanism for adaptation to mechanical forces in the lung. Respir Physiol Neurobiol. 2003 137 : 151 68.
6. Kuo K-H, Herrera AM, Wang L, Pare PD, Ford LE, Stephens NL, Seow CY. Structure-function correlation in airway smooth muscle adapted to different lengths. Am J Physiol. 2003 285 : C384 90.
7. Mulvany MJ. Abnormalities of the resistance vasculature in hypertension: correction by vasodilatory therapy. Pharmacol Rep. 2005 57 : 144 50.
8. Wang L, Pare PD, Seow CY. Effect of chronic passive length change on airway smooth muscle length-tension relationship. J Appl Physiol. 2001 90 : 734 40.
9. Gunst SJ, Wu M-F. Plasticity of airway smooth muscle stiffness and extensibility: role of length adaptive mechanisms. J Appl Physiol. 2001 90 : 741 9.
10. Ohanian V, Gatfield K, Ohanian J. Role of the actin cytoskeleton in G-protein-coupled receptor activation of PYK2 and paxillin in vascular smooth muscle. Hypertension. 2005 46 : 93 100.
11. i in isolated pressurised resistance arteries. J Vasc Res. 2003 40 : 1 10.
12. Calderwood DA. Integrin activation. J Cell Sci. 2004 117 : 657 66.
13. Li S, Kim M, Hu Y-L, Jalali S, Schlaeper DD, Hunter T, Chien S, Shyy JJ. Fluid sheer stress activation of focal adhesion kinase: linking to mitogen activated protein kinases. J Biol Chem. 1997 272 : 30455 62.
14. Ruwhof C, van der Laarse A. Mechanical stress-induced cardiac hypertrophy: mechanisms and signal transduction pathways. Cardiovasc Res. 2000 47 : 23 37.
15. Boutahar N, Guignanclon A, Vico L Lafage-Proust MH. Mechanical strain on osteoblasts activates autophosphorylation of focal adhesion kinase and proline-rich tyrosine kinase 2 tyrosine sites involved in ERK activation. J Biol Chem. 2004 279 : 30588 99.
16. Ishibe S, Joly D, Liu Z-X, Cantley LG. Paxillin serves as an ERK-regulated scaffold for coordinating FAK and Rac activation in epithelial morphogenesis. Mol Cell. 2004 16 : 257 67.
17. Williams SJ, White BG, Macphee DJ. Expression of
18. Macphee DJ, Lye SJ. Focal adhesion signaling in rat myometrium is abruptly terminated with the onset of labour. Endocrinology. 2000 141 : 274 83.
19. Li Y, Je HD, Malek S, Morgan KG. ERK1/2-mediated phosphorylation of myometrial caldesmon during pregnancy and labor. Am J Physiol Regul Integr Comp Physiol. 2003 284 : 192 9.
20. Li Y, Je HD, Malek S, Morgan KG. Focal adhesion signaling is required for myometrial ERK activation and contractile pheno-type switch before labor. J Cell Biochem. 2007 100 : 129 40.
21. Riley M, Baker PN, Tribe RM, Taggart MJ. Expression of scaffolding, signalling and contractile-filament proteins in human myometria: effects of pregnancy and labour. J Cell Mol Med. 2005 9 : 122 34.
22. Riley M, Wu X, Baker PN, Taggart MJ. Gestational-dependent changes in the expression of signal transduction and contractile filament-associated proteins in mouse myometrium. J Soc Gynecol Invest. 2005 12 : e33 43.
23. Goldspink DF, Douglas AJ. Protein turnover in gravid and nongravid horns of uterus in pregnant rats. Am J Physiol. 1988 254 : E549 54.
24. Laguens R, Lagrutta J. Fine structure of human uterine muscle in pregnancy. Am J Obstet Gynecol. 1964 89 : 1040 8.
25. Csapo A, Erdos T, De Mattos CR, Gramss E, Moscowitz C. Stretch-induced uterine growth, protein synthesis and function. Nature. 1965 207 : 1378 9.
26. Shynlova O, Oldenhof A, Dorogin A, Xu Q, Mu J, Nashman N, Lye SJ. Myometrial apoptosis: activation of the caspase cascade in the pregnant rat myometrium at midges-tation. Biol Reprod. 2006 74 : 839 49.
27. Bai TR, Bates JH, Brusasco V, Camoretti-Mercado B, Chitano P, Deng LH, Dowell M, Fabry B, Ford LE, Fredberg JJ, Gerthoffer WT, Gilbert SH, Gunst SJ, Hai CM, Halayko AJ, Hirst SJ, James AL, Janssen LJ, Jones KA, King GG, Lakser OJ, Lambert RK, Lauzon AM, Lutchen KR, Maksym GN, Meiss RA, Mijailovich SM, Mitchell HW, Mitchell RW, Mitzner W, Murphy TM, Pare PD, Schellenberg RR, Seow CY, Sieck GC, Smith PG, Smolensky AV, Solway J, Stephens NL, Stewart AG, Tang DD, Wang L. On the terminology for describing the length-force relationship and its changes in airway smooth muscle. J Appl Physiol. 2004 97 : 2029 34.
28. Kim HR, Hai CM. Mechanisms of mechanical strain memory in airway smooth muscle. Can J Physiol Pharmacol. 2005 83 : 811 5.
29. Morano I, Koehlen S, Haase H, Erb G, Baltas LG, Rimbach S, Wallwiener D, Bastert G. Alternative splicing and cycling kinetics of myosin change during hypertrophy of human smooth muscle cells. J Cell Biochem. 1997 64 : 171 81.
30. Sparrow M, Mohammad MA, Arner A, Hellstrand P, Ruegg JC. Myosin composition and functional properties of smooth muscle from the uterus of pregnant and non-pregnant rats. Pflugers Arch. 1998 412 : 624 33.
31. Shynlova O, Mitchell JA, Tsampalieros A, Langille BL, Lye SJ. Progesterone and gravidity differentially regulate expression of extracellular matrix components in the pregnant rat myometrium. Biol Reprod. 2004 70 : 986 92.
32. Shynlova O, Tsui P, Dorogin A, Chow M, Lye SJ. Expression and localisation of alpha-smooth muscle actin and gamma-actins in the pregnant rat myometrium. Biol Reprod. 2005 73 : 773 80.
33. Shynlova O, Williams SJ, Draper H, White BG, MacPhee DJ, Lye SJ. Uterine stretch regulates temporal and spatial expression of fibronectin protein and its alpha 5 integrin receptor in myometrium of unilaterally pregnant rats. Biol Reprod. 2007 77 : 880 8.
34. Croke JM, Pike LRG, MacPhee DJ. The focal adhesion protein Hic-5 is highly expressed in the rat myometrium during late pregnancy and labour and co-localises with FAK. Reprod Biol Endocrinol. 2007 5 : 22.
35. Tang DD, Turner CE, Gunst SJ. Expression of non-phosphorylatable paxillin mutants in canine tracheal smooth muscle inhibits tension development. J Physiol. 2003 553 : 21 35.
36. Seko Y, Takahashi N, Tobe K, Kadowaki T, Yazaki Y. Pulsatile stretch activates mitogen-activated protein kinase (MAPK) family members and focal adhesion kinase (p125(FAK)) in cultured rat cardiac myocytes. Biochem Biophys Res Commun. 1999 259 : 8 14.
37. Ishida T, Haneda M, Maeda S, Koya D, Kikkawa R. Stretch-induced overproduction of fibronectin in mesangial cells is mediated by the activation of mitogen-acti-vated protein kinase. Diabetes. 1999 48 : 595 602.
38. Oldenhof AD, Shynlova OP, Liu M, Langille BL, Lye SJ. Mitogen-activated protein kinases mediate stretch-induced c-fos mRNA expression in myometrial smooth muscle cells. Am J Physiol Cell Physiol. 2002 283 : C1530 9.
39. Jalali S, Li YS, Sotoudeh M, Yuan S, Li S, Chien S, Shyy JY. Shear stress activates p60src-Ras-MAPK signaling pathways in vascular endothelial cells. Arterioscler Thromb Vasc Biol. 1998 18 : 227 34.
40. Li YP, Reznichenko M, Tribe RM, Hess PE, Taggart M, Morgan KG. A novel concept on human myometrial activation in contractile function during late pregnancy. Anesthesiology. 2007 106 : A53.
41. Nishinaka K, Fukuda Y. Changes in extracellular matrix materials in the uterine myometrium of rats during pregnancy and postparturition. Acta Pathol Jpn. 1991 41 : 122 32.
42. Stewart EA, Floor AE, Jain P, Nowak RA. Increased expression of messenger RNA for collagen type I, collagen type III and fibronectin in myometrium of pregnancy. Obstet Gynecol. 1995 86 : 417 22.
43. Gabella G. Structural apparatus for force transmission in smooth muscles. Physiol Rev. 1984 64 : 455 77.
44. Kuo K-H, Seow CY. Contractile filament architecture and force transmission in swine airway smooth muscle. J Cell Sci. 2004 117 : 1503 11.
45. Gerthoffer WT, Gunst SJ. Focal adhesion and small heat shock proteins in the regulation of actin remodelling and contractility in smooth muscle. Am J Physiol. 2001 91 : 963 71.
46. Liu Z-X, Yu CF, Nickel C, Thomas S, Cantley LG. Hepatocyte growth factor induces ERK-dependent paxillin phospho-rylation and regulates paxillin-focal adhesion kinase association. J Biol Chem. 2002 277 : 10452 8.