Interaction between the bound Mg·ATP and the Walker a serine residue in NBD2 of multidrug resistance-associated protein MRP1 plays a crucial role for the ATP-dependent leukotriene C4 transport

Biochemistry

Volumn 47, Issue 32, 2008, Pages 8456-8464

  Yang, Runying ^a   Scavetta, Robert ^b   Chang, Xiu Bao ^a  

^a MAYO GRADUATE SCHOOL   (United States)

^b ARIZONA STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; HYDROGEN; HYDROGEN BONDS; NONMETALS; STRUCTURAL ANALYSIS;

MULTI-DRUG RESISTANCE;

MAGNESIUM PRINTING PLATES;

ADENOSINE TRIPHOSPHATE; HYDROXYL GROUP; LEUKOTRIENE C4; MAGNESIUM; MULTIDRUG RESISTANCE PROTEIN 1; NBD1 PROTEIN; PROTEIN; SERINE;

ANIMAL CELL; ARTICLE; BINDING AFFINITY; CONTROLLED STUDY; HYDROLYSIS; MUTATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN FOLDING; PROTEIN FUNCTION; PROTEIN INTERACTION; PROTEIN TRANSPORT; TRANSPORT KINETICS;

ADENOSINE TRIPHOSPHATE; AMINO ACID MOTIFS; ANIMALS; BIOLOGICAL TRANSPORT; CELL LINE; CRICETINAE; HUMANS; LEUKOTRIENE C4; MAGNESIUM; MULTIDRUG RESISTANCE-ASSOCIATED PROTEINS; PROTEIN INTERACTION DOMAINS AND MOTIFS; SERINE;

EID: 49449115300     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi8007643     Document Type: Article

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