Role of vitamin A in determining nephron mass and possible relationship to hypertension

Journal of Nutrition

Volumn 138, Issue 8, 2008, Pages 1407-1410

  Bhat, Pangala V ^a   Manolescu, Daniel Constantin ^a  

^a NONE

Author keywords

[No Author keywords available]

Indexed keywords

PROTEIN TYROSINE KINASE; RETINOID; RETINOL;

APOPTOSIS; CELL DIFFERENTIATION; CELL PROLIFERATION; DEVELOPED COUNTRY; DEVELOPING COUNTRY; DISEASE ASSOCIATION; HUMAN; HYPERTENSION; IMMUNITY; KIDNEY DEVELOPMENT; MATERNAL NUTRITION; NEPHRON; PROTEIN EXPRESSION; RETINOL DEFICIENCY; REVIEW; VITAMIN BLOOD LEVEL; VITAMIN METABOLISM;

RODENTIA;

EID: 49449102610     PISSN: 00223166     EISSN: 15416100     Source Type: Journal    
DOI: 10.1093/jn/138.8.1407     Document Type: Review

References (36)

1. Quadro L, Hamberger L, Gottesman ME, Wang F, Colantuoni V, Blaner WS, Mendelsohn CL. Pathways of vitamin A delivery to the embryo: insights from a new tunable model of embryonic vitamin A deficiency. Endocrinology. 2005;146:4479-90.
2. Moise AR, Noy N, Palczewski K, Blaner WS. Delivery of retinoid-based therapies to target tissues. Biochemistry. 2007;46:4449-58.
3. Chambon P. A decade of molecular biology of retinoic acid receptors. FASEB J. 1996;10:940-54.
4. Molotkov A, Fan X, Deltour L, Foglio MH, Martras S, Farrés J, Parés X, Duester G. Stimulation of retinoic acid production and growth by ubiquitously-expressed alcohol dehydrogenase Adh3. Proc Natl Acad Sci USA. 2002;99:5337-42.
5. Sandell LL, Sanderson BW, Moiseyev G, Johnson T, Mushegian A, Young K, Rey JP, Ma JX, Staehling-Hampton K, et al. RDH10 is essential for synthesis of embryonic retinoic acid and is required for limb, craniofacial, and organ development. Genes Dev. 2007;21:1113-24.
6. Duester G, Mic FA, Molotkov A. Cytosolic retinoid dehydrogenases govern ubiquitous metabolism of retinol to retinaldehyde followed by tissue-specific metabolism to retinoic acid. Chem Biol Interact. 2003;143:201-10.
7. Bhat PV. Role of retinal dehydrogenase type 1 (RALDH1) in retinoic acid biosynthesis. In: Weiner H, editor. Enzymology and molecular biology of carbonyl metabolism; 12. Purdue University Press, West Lafayette, Indiana; 2005. p. 66-72.
8. Gagnon I, Duester G, Bhat PV. Kinetic analysis of mouse retinal dehydrogenase 2 (RALDH2) for retinal substrates. Biochim Biophys Acta. 2002;1596:156-62.
9. Grun F, Hirose Y, Kawauchi S, Ogura T, Umesono K. Aldehyde dehydrogenase 6, a cytosolic retinaldehyde dehydrogenase prominently expressed in sensory neuroepithelia during development. J Biol Chem. 2000;275:41210-8.
10. Haselbeck RJ, Hoffmann I, Duester G. Distinct functions for Aldh1 and RALDH2 in the control of ligand production for embryonic retinoid signalling pathways. Dev Genet. 1999;25:353-64.
11. Mic FA, Molotkov A, Fan F, Cuenca AE, Duester G. RALDH3, a retinaldehyde dehydrogenase that generates retinoic acid, is expressed in the ventral retina, otic vesicle and olfactory pit during mouse development. Mech Dev. 2000;97:227-30.
12. Niederreither K, Subbarayan V, Dolle P, Chambon P. Embryonic retinoic acid synthesis is essential for early mouse post-implantation development. Nat Genet. 1999;21:444-8.
13. Dupe V, Matt M, Garnier JM, Chambon P, Mark M, Ghyselinck NB. A new born lethal defect due to inactivation of retinaldehyde dehydrogenase type 3 is prevented by maternal retinoic acid treatment. Proc Natl Acad Sci USA. 2003;100:14036-41.
14. Niederreither K, Abu-Abed S, Schuhbaur B, Petkovich M, Chambon P, Dolle P. Genetic evidence that oxidative derivatives of retinoic acid are not involved in retinoid signalling during mouse development. Nat Genet. 2002;31:84-8.
15. Lipschutz JH. Molecular development of the kidney: a review of the results of gene disruption studies. Am J Kidney Dis. 1998;31:383-97.
16. Moritz KM, Dodic M, Wintour EM. Kidney development and the fetal programming of adult disease. Bioessays. 2003;25:212-20.
17. Wilson JG, Roth CB, Warkany J. An analysis of the syndrome of malformations induced by maternal vitamin A deficiency. Effects of restoration of vitamin A at various times during gestation. Am J Anat. 1953;92:189-217.
18. Mendelsohn C, Lohnes D, Decimo D, Lufkin T, LeMeur M, Chambon P, Mark M. Function of retinoic acid receptors (RARs) during development. II Multiple abnormalities at various stages of organogenesis in RAR double mutants. Development. 1994;120:2749-71.
19. Makrakis J, Zimanyi MA, Black MJ. Retinoic acid enhances nephron endowment in rats exposed to maternal protein restriction. Pediatr Nephrol. 2007;22:1861-7.
20. Batourina E, Gim S, Bello N, Shy M, Clagett-Dame M, Srinivas S, Constantini F, Mendelsohn C. Vitamin A controls epithelial/mesenchymal interactions through ret expression. Nat Genet. 2001;27:74-8.
21. Mendelsohn C, Batourina E, Fung S, Gilbert T, Dodd J. Stromal cells mediate retinoid-dependent functions essential for renal development. Development. 1999;126:1139-48.
22. Humes HD, Cieslinski DA. Interaction between growth factors and retinoic acid in the induction of kidney tubulogenesis in tissue culture. Exp Cell Res. 1992;201:8-15.
23. Vilar J, Gilbert T, Moreau E, Merlet-Benichou C. Metanephros organogenesis is highly stimulated by vitamin A derivatives in organ culture. Kidney Int. 1996;49:1478-87.
24. Lelièvre-Pégorier M, Vilar J, Ferrier M, Moreau E, Freund N, Gilbert T, Merlet-Benichou C. Mild vitamin A deficiency leads to inborn nephron deficit in the rat. Kidney Int. 1998;54:1455-62.
25. Goodyer P, Kurpad A, Rekha S, Muthayya S, Dwarkanath P, Iyengar A, Philip B, Mhaskar A, Benjamin A, et al. Effects of maternal vitamin A status on kidney development: a pilot study. Pediatr Nephrol. 2007;22:209-14.
26. Gilbert T, Merlet-Benichou C. Retinoids and nephron mass control. Pediatr Nephrol. 2000;14:1137-44.
27. Merlet-Benichou C, Gilbert T, Muffat-Jolly M, Lelievre-Pegorier M, Leroy B. Intrauterine growth retardation leads to a permanent nephron deficit in the offspring. Pediatr Nephrol. 1994;8:175-80.
28. Manning J, Vehaskari VM. Low birth weight-associated adult hypertension in the rat. Pediatr Nephrol. 2001;16:417-22.
29. Woods LL. Maternal nutrition and predisposition to later kidney disease. Curr Drug Targets. 2007;8:906-13.
30. Poladia DP, Kish K, Kutay B, Bauer J, Baum M, Bates CM. Link between reduced nephron and hypertension: studies in a mutant mouse model. Pediatr Res. 2006;59:489-93.
31. Hoy WE, Bertram JF, Denton RD, Zimanyi M, Samuel T, Hughson MD. Nephron number, glomerular volume, renal disease and hypertension. Curr Opin Nephrol Hypertens. 2008;17:258-65.
32. Brenner BM, Garcia DL, Anderson S. Glomeruli and blood pressure. Less of one, more the other? Am J Hypertens. 1988;1:335-47.
33. Azuma H, Nadeau K, Mackenzie HS, Brenner BM. Nephron mass modulates the hemodynamic, cellular, and molecular response of the rat renal allograft. Transplantation. 1997;63:519-28.
34. Cullen-McEwen LA, Drago J, Bertram JF. Ephron endowment in glial cell line-derived neurotrophic factor (GDNF) heterozygous mice. Kidney Int. 2001;60:31-6.
35. Keller G, Zimmer G, Mall G, Ritz E, Amann K. Nephron number in patients with primary hypertension. N Engl J Med. 2003;348:101-8.
36. Hoy WE, Hughson MD, Singh GR, Douglas-Denton R, Bertram JF. Reduced nephron number and glomerulomegaly in Australian Aborginals: a group at high risk for renal disease and hypertension. Kidney Int. 2006;70:104-10.