Nephron mass modulates the hemodynamic, cellular, and molecular response of the rat renal allograft

Transplantation

Volumn 63, Issue 4, 1997, Pages 519-528

  Azuma, Haruhito ^a,c   Nadeau, Kari ^a,d   Mackenzie, Harald S ^b   Brenner, Barry M ^b   Tilney, Nicholas L ^a,b  

^a HARVARD MEDICAL SCHOOL   (United States)

^b BRIGHAM AND WOMEN S HOSPITAL   (United States)

^c OSAKA MEDICAL COLLEGE   (Japan)

^d BOSTON CHILDREN S HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL MODEL; ANIMAL TISSUE; ARTERIOSCLEROSIS; ARTICLE; CONTROLLED STUDY; GLOMERULOSCLEROSIS; GRAFT FAILURE; GRAFT REJECTION; HEMODYNAMICS; IMMUNOHISTOLOGY; KIDNEY ALLOGRAFT; KIDNEY MASS; MALE; NEPHRON; NONHUMAN; PRIORITY JOURNAL; PROTEINURIA; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

ANIMALS; GLOMERULAR FILTRATION RATE; HEMODYNAMIC PROCESSES; HISTOCOMPATIBILITY ANTIGENS CLASS II; INTERCELLULAR ADHESION MOLECULE-1; KIDNEY; KIDNEY TRANSPLANTATION; MALE; NEPHRONS; RANTES; RATS; RATS, INBRED F344; RATS, INBRED LEW; TRANSPLANTATION, HOMOLOGOUS;

EID: 0031046924     PISSN: 00411337     EISSN: None     Source Type: Journal    
DOI: 10.1097/00007890-199702270-00006     Document Type: Article

References (38)

1. Terasaki PI, Gjertson DW, Cecka JM, Takemoto S. HLA matching for improved cadaver kidney allocation. Curr Opin Nephrol Hypertens 1994; 3: 585.
2. Tilney NL, Whitley WD, Diamond JR, Kupiec-Weglinski JW, Adams DH. Chronic rejection - an undefined conundrum. Transplantation 1991; 52: 389.
3. Paul LC, Bendiktsson H. Chronic transplant rejection: magnitude of the problem and pathogenetic mechanisms. Transplant Rev 1993; 7: 96.
4. Almond PS, Matas AJ, Gillingham KJ, et al. Risk factors for chronic rejection in renal allograft recipients. Transplantation 1993; 55: 752.
5. Tullius SG, Tilney NL. Both alloantigen-dependent and -independent factors influence chronic allograft rejection. Transplantation 1995; 59: 313.
6. Tullius SG, Heemann U, Hancock WW, Azuma H, Tilney NL. Long-term kidney isografts develop functional and morphologic changes that mimic those of chronic allograft rejection. Ann Surg 1994; 220: 425.
7. Hostetter TH, Olson JL, Rennke HG, et al. Hyperfiltration in remnant nephrons: a potentially adverse response to renal ablation. Am J Physiol 1981; 241: F85.
8. Mackenzie HS, Tullius SG, Heemann UW, et al. Nephron supply is a major determinant of long-term renal allograft outcome in rats. J Clin Invest 1994; 94: 2148.
9. Heemann UW, Azuma H, Tullius SG, Mackenzie H, Brenner BM, Tilney NL. The contribution of reduced functioning mass to chronic kidney allograft dysfunction in rats. Transplantation 1994; 58: 1317.
10. Diamond JR, Tilney NL, Frye J, et al. Progressive albuminuria and glomerulosclerosis in a rat model of chronic renal allograft rejection. Transplantation 1992; 54: 710.
11. Hancock WH, Whitley WD, Tullius SG, et al. Cytokines, adhesion molecules, and the pathogenesis of chronic rejection of rat renal allografts. Transplantation 1993; 56: 643.
12. Brenner BM, Milford EL. Nephron underdosing: a programmed cause of chronic renal allograft failure. Am J Kidney Dis 1993; 21: 66.
13. Nadeau KC, Azuma H, Tilney NL. Sequential cytokine dynamics in chronic rejection of rat renal allografts: roles for cytokines RANTES and MCP-1. Proc Natl Acad Sci USA 1995; 92: 8729.
14. Bradley M, Schuman GB, Ward PCJ. Examination of urine. In: Henry JB, ed. Todd, Sanford, Davidsohn's clinical diagnosis and management by laboratory methods. Philadelphia: Saunders, 1979: 604.
15. Mackenzie HS, Azuma H, Troy JL, Rennke HG, Tilney NL, Brenner BM. Augmenting renal mass at transplantation abrogates chronic renal allograft failure in rats. Proc Assoc Am Phys 1996; 108: 127.
16. Tamatani T, Miyasaka M. Identification of monoclonal antibodies reactive with the rat homolog of ICAM-1, and evidence for a differential involvement of ICAM-1 in the adherence of resting versus activated lymphocytes to high endothelial cells. Int Immunol 1990; 2: 165.
17. Brenner BM. Hemodynamically mediated glomerular injury and the progressive nature of renal disease. Kidney Int 1983; 23: 647.
18. Cook HT, Smith J, Salmon JA, Cattell V. Functional characteristics of macrophages in glomerulonephritis in the rat. O2-generation, MHC class II expression, and eicosanoid synthesis. Am J Pathol 1989; 134: 431.
19. Shankland SJ, Ly H, Thai K, Scholey JW. Increased glomerular capillary pressure alters glomerular cytokine expression. Circ Res 1994; 75: 844.
20. Floege J, Johnson RJ, Couser WG. Mesangial cells in the pathogenesis of progressive glomerular disease in animal models. Clin Invest 1992; 70: 857.
21. Tullius SG, Heemann U, Azuma H, Pradham P, Tilney NL. Early ischemic injury leads to long-term functional and morphologic deterioration of naive rat kidneys and may contribute to changes of chronic allograft rejection. Transplant Proc 1994; 26: 2041.
22. Goes N, Urmson J, Ramassar V, Halloran PF. Ischemic acute tubular necrosis induces an extensive local cytokine response: evidence for induction of interferon-γ, transforming growth factor-β1, granulocyte-macrophage colony-stimulating factor, interleukin-2, and interleukin-10. Transplantation 1995; 59: 565.
23. Paul LC. Functional and histologic characteristics of chronic renal allograft rejection. Clin Transplant 1994; 319.
24. Feehally J, Harris KP, Bennett SE, Walls J. Is chronic renal transplant rejection a non-immunological phenomenon? Lancet 1986; 2: 486.
25. Terasaki PI, Koyama H, Cecka JM, Gjertson DW. The hyperfiltration hypothesis in human renal transplantation. Transplantation 1994; 57: 1450.
26. Benigni A, Perico N, Gaspari F, Imberti O, Bellizzi L, Remuzzi G. Increased renal endothelin production in rats with reduced renal mass. Am J Physiol 1991; F331.
27. Brooks DP, Contino LC, Storer B, Ohlstein EH. Increased endothelin excretion in rats with renal failure induced by partial nephrectomy. Br J Pharmacol 1991; 104: 987.
28. Simons J, Provoost AP, Anderson S, et al. Pathogenesis of glomerular injury in the fawn-hooded rat: early glomerular capillary hypertension predicts glomerular sclerosis. J Am Soc Nephrol 1993; 3: 1775.
29. Masuyama J, Minato N, Kano S. Mechanisms of lymphocyte adhesion to human vascular endothelial cells in culture: T lymphocyte adhesion to endothelial cells through endothelial HLA-DR antigens induced by gamma Interferon. J Clin Invest 1986; 77: 1596.
30. Kingma I, Chea R, Davidoff A, Benediktsson H, Paul LC. Glomerular capillary pressures in long-surviving rat renal allografts. Transplantation 1993; 56: 53.
31. Sterzel RB, Schulze LE, Marx M. Cytokines and mesangial cells. Kidney Int Suppl 1993; 39: S26.
32. Radeke HH, Resch K. The inflammatory function of renal glomerular mesangial cells and their interaction with the cellular immune system. Clin Invest 1992; 70: 825.
33. Pattison J, Nelson PJ, Huie P, von Leuttichau I, Farshid G, Sibley RK. RANTES chemokine expression in cell-mediated transplant rejection of the kidney. Lancet 1994; 343: 209.
34. Schall TJ, Bacon K, Toy KJ, Goeddel DV. Selective attraction of monocytes and T lymphocytes of the memory phenotype by cytokine RANTES. Nature 1990; 347: 669.
35. Heeger P, Wolf G, Meyers C, Sun MJ, O'Farrell SC, Krensky AM. Isolation and characterization of cDNA from renal tubular epithelium encoding murine RANTES. Kidney Int 1992; 41: 220.
36. Hirano T, Akira S, Taga T, Kishimoto T. Biological and clinical aspects of interleukin 6. Immunol Today 1990; 11: 443.
37. Bruijn JA, Roos A, deGeus B, deHeer E. Transforming growth factor-beta and the glomerular extracellular matrix in renal pathology. J Lab Clin Med 1994; 123: 34.
38. Sharma K, Ziyadeh FN. The emerging role of transforming growth factor-beta in kidney diseases. Am J Physiol 1994; 266 (6 Pt 2): F829.