Alzheimer's disease - Towards more patient-centred and meaningful clinical outcomes

Annals of the Academy of Medicine Singapore

Volumn 37, Issue 7, 2008, Pages 535-537

  Jing, Jih Chin ^a  

^a TAN TOCK SENG HOSPITAL   (Singapore)

Author keywords

[No Author keywords available]

Indexed keywords

CHOLINESTERASE INHIBITOR; MEMANTINE;

AGING; ALZHEIMER DISEASE; ALZHEIMER DISEASE ASSESSMENT SCALE COGNITION; BRAIN DISEASE; CADAVER; CAREGIVER; CLINICAL DEMENTIA RATING; COGNITIVE DEFECT; DAILY LIFE ACTIVITY; DEMENTIA; DISEASE COURSE; DRUG EFFICACY; EDITORIAL; FUNCTIONAL ASSESSMENT; HISTORY OF MEDICINE; HUMAN; NEUROLOGIC DISEASE; NEUROPSYCHOLOGICAL TEST; PATIENT CARE; PSYCHOLOGICAL RATING SCALE; PSYCHOMETRY; SENILE PLAQUE; TREATMENT OUTCOME;

EID: 49449102119     PISSN: 03044602     EISSN: 29724066     Source Type: Journal    
DOI: None     Document Type: Editorial

References (28)

1. Maurer K, Maurer U. Alzheimer: The Life of a Physician & Career of a Disease. New York: Columbia University Press, 2003.
2. Graeber MB, Koesel S, Egensperger R, Banati RB, Mueller U, Bise K, et al. Rediscovery of the case described by Alois Alzheimer in 1911: historical, histological and molecular genetic analysis. Neurogenetics 1997;1:73-80.
3. Dementia in the Asia Pacific region: the epidemic is here. A report by Asia Pacific members of the Alzheimer Disease International, 2006.
4. Kua EH, Koh SM. Prevalence of dementia among elderly Chinese and Malay residents of Singapore. Int Psychogeriatr 1995;7:439-46.
5. Sahadevan S, Saw SM, Gao W, Tan CSL, Chin JJ, Hong CY, et al. Ethnic differences in Singapore's dementia prevalence: the SPEED study. J Am Geriatr Soc 2008 (In print).
6. Brayne C, Gao L, Dewey M, Matthews FE, and Medical Research Council Cognitive Function and Ageing Study Investigators. Dementia before death in ageing societies - the promise of prevention and the reality. PLoS Med 2006;3:e397.
7. Raina P, Santaguida P, Ismaila A, Patterson C, Cowan D, Levine M, et al. Effectiveness of cholinesterase inhibitors and memantine for treating dementia: evidence review for a clinical practice guideline Ann Intern Med 2008;148:379-97.
8. Leber P. Guidelines for the Clinical Evaluation of Antidementia Drugs. Washington, DC: Food and Drug Administration, 1990 November;4:4.4.4.
9. Rosen WG, Mohs RC, Davis KL. A new rating scale for Alzheimer's disease. Am J Psychiatry 1984;141:1356-64.
10. Boothby H, Mann AH, Barker A. Factors determining inter-rater agreement with rating global change in dementia: the CIBIC-plus. Int J Geriatr Psychiatry 1995;10:1037-45.
11. Berg L. Clinical dementia (CDR). Psychopharmacol Bull 1988;24:637-9.
12. Morris JC. The Clinical Dementia Rating (CDR): current version and scoring rules. Neurology 1993;43:2412-4.
13. Oremus M, Perrault A, Demers L, Wolfson C. Review of outcome measurement instruments in Alzheimer's disease: Psychometric properties of global scales. J Geriatric Psychiatry Neurol 2000;13:197-205.
14. APA Work Group on Alzheimer's Disease and other Dementias, Rabins PV, Blacker D, Rovner BW, Rummans T, Schneider LS, Tariot PN, et al. American Psychiatric Association practice guideline for the treatment of patients with Alzheimer's disease and other dementias. 2nd ed. Am J Psychiatry 2007;164(12 Suppl):5-56.
15. Kitwood T, Bredin K. Towards a theory of dementia care: personhood and well-being. Ageing Soc 1992;12:269-87.
16. Rabins PV, Kasper J, Black BB, Patrick DL. Concepts and methods in the development of the ADRQL: An instrument for assessing health-related quality of life in persons with Alzheimer's disease. J Mental Health Aging 1999;5:33-48.
17. Lyketsos CG, Gonzales-Salvador T, Chin JJ, Baker A, Black B, Rabins P. A follow-up study of change in quality of life among persons with dementia residing in a long-term care facility. Int J Geriatr Psychiatry 2003;18:275-81.
18. Brod M, Stewart AL, Sands L, Walton P. Conceptualization and measurement of quality of life in dementia: the dementia quality of life instrument (DQoL). Gerontologist 1999;39:25-35.
19. Post SG, Whitehouse PJ. Emerging antidementia drugs: a preliminary ethical view. J Am Geriatr Soc 1998;46:784-7.
20. Thomas P, Lalloué F, Preux PM, Hazif-Thomas C, Pariel S, Inscale R, et al. Dementia patients caregivers quality of life: the PIXEL study. Int J Geriatr Psychiatry 2006;21:50-6.
21. Kua EH, Tan SL. Stress of caregivers of dementia patients in the Singapore Chinese family. Int J Geriatr Psychiatry 1997;12:466-9.
22. Lim JPP, Sahadevan S, Choo GK, Anthony P. Burdens of caregiving in mild to moderate dementia: an Asian experience. Int Psychogeriatr 1999;11:411-20.
23. McFall S, Miller BH. Caregiver burden and nursing home admission of frail elderly persons. J Gerontol 1992;47:S73-S79.
24. Wilkinson D. Caregiver burden in Alzheimer's disease: the impact of cholinesterase inhibitors. CPD Bulletin Old Age Psychiatry 2001;2:76-9.
25. Cummings JL, Schneider L, Tariot PN, Kershaw PR, Yuan W. Reduction of behavioral disturbances and caregiver distress by galantamine in patients with Alzheimer's disease. Am J Psychiatry 2004;16:532-8.
26. Fillit HM, Gutterman EM, Brooks RL. Impact of donepezil on caregiving burden for patients with Alzheimer's disease. Int Psychogeriatr 2000;12:389-401.
27. Alzheimer's Association research roundtable highlights scales as outcomes measures for Alzheimer clinical Trials. Alzheimer's & Dementia 2008;4:311-4.
28. Sachs GA. Dementia and the goals of care. J Am Geriatr Soc 1998;46:782-3.