Rediscovery of the case described by Alois Alzheimer in 1911: Historical, histological and molecular genetic analysis

Neurogenetics

Volumn 1, Issue 1, 1997, Pages 73-80

  Graeber, M B ^a   Kosel S ^b   Egensperger, R ^c   Banati, R B ^d   Muller U ^e   Bise, K ^b   Hoff, P ^f   Moller H J ^f   Fujisawa, K ^g   Mehraein, P ^b  

^a MAX PLANCK INSTITUTE OF PSYCHIATRY   (Germany)

^b UNIVERSITY OF MUNICH   (Germany)

^c HANNOVER MEDICAL SCHOOL   (Germany)

^d HAMMERSMITH HOSPITAL   (United Kingdom)

^e JUSTUS LIEBIG UNIVERSITY   (Germany)

^f LUDWIG MAXIMILIANS UNIVERSITY   (Germany)

^g TOKYO METROPOLITAN INSTITUTE OF MEDICAL SCIENCE   (Japan)

Author keywords

Alzheimer disease; Amyloid plaques; Amyloid precursor protein gene; Apolipoprotein E gene; Neurofibrillary tangles

Indexed keywords

AMYLOID PRECURSOR PROTEIN;

ALZHEIMER DISEASE; ARTICLE; BRAIN; EXON; GENETICS; HISTORY; HUMAN; MALE; METABOLISM; MUTATION; NUCLEOTIDE SEQUENCE; PATHOLOGY; POLYMERASE CHAIN REACTION;

ALZHEIMER DISEASE; AMYLOID BETA-PROTEIN PRECURSOR; BRAIN; DNA MUTATIONAL ANALYSIS; EXONS; HISTORY, 20TH CENTURY; HUMANS; MALE; MUTATION; POLYMERASE CHAIN REACTION;

EID: 0031128758     PISSN: 13646745     EISSN: None     Source Type: Journal    
DOI: 10.1007/s100480050011     Document Type: Article

References (31)

1. Alzheimer, A. (1907) Über eine eigenartige Erkrankung der Hirnrinde. Allg. Z. Psychiat. Psych.-Gerichtl. Med., 64, 146-148.
2. O'Brien, C. (1996) Auguste D. and Alzheimer's disease. Science, 273, 28.
3. Kraepelin, E. (1910) Psychiatrie. Ein Lehrbuch für Studierende und Ärzte. II. Band, Klinische Psychiatrie. Verlag Johann Ambrosius Barth, Leipzig.
4. Alzheimer, A. (1911) Über eigenartige Krankheitsfälle des späteren Alters. Zbl. ges. Neurol. Psych., 4, 356-385.
5. Bick, K.L. (1987) A characteristic disease of the cerebral cortex. In Bick K, Amaducci L, Pepeu G (eds) The Early Story of Alzheimer's disease, Raven Press, New York.
6. Förstl, H. and Levy, R. (1991) On certain peculiar diseases of old age. Hist. Psychiatry, 2, 71-101.
7. Kösel, S. and Graeber, M.B. (1993) Non-radioactive direct sequencing of PCR products amplified from neuropathological specimens. Brain Pathol., 3, 421-424.
8. Kösel, S. and Graeber, M.B. (1994) Use of neuropathological tissue for molecular genetic studies: Parameters affecting DNA extraction and polymerase chain reaction. Acta Neuropathol., 88, 19-25.
9. Egensperger, R., Kösel, S., Schnabel, R., Mehraein, P. and Graeber, M.B. (1995) Apolipoprotein E genotype and neuropathological phenotype in two members of a German family with chromosome 14-linked early onset Alzheimer's disease. Acta Neuropathol., 90, 257-265.
10. Wenham, P.R., Price, W.H. and Blundell, G. (1991) Apolipoprotein E genotyping by one-stage PCR. Lancet, 337, 1158-1159.
11. Yoshikai, S., Sasaki, H., Dohura, K., Furuya, H. and Sakaki, Y. (1990) Genomic organization of the human amyloid beta-protein precursor gene. Gene, 87, 257-263.
12. Levy, E., Carman, M.D., Fernandez-Madrid, I.J., Power, M.D., Lieberburg, I., Van Duinen, S.G., Bots, G.T.A.M., Luyendijk, W. and Frangione, B. (1990) Mutation of the Alzheimer's disease amyloid gene in hereditary cerebral hemorrhage, Dutch type. Science, 248, 1124-1126.
13. Goate, A., Chartier-Harlin, M.C., Mullan, M., Brown, J., Crawford, F., Fidani, L., Giuffra, L., Haynes, A., Irving, N., James, L., Mant, R., Newton, P., Rooke, K., Roques, P., Talbot, C., Pericak-Vance, M., Roses, A., Williamson, R., Rossor, M., Owen, M. and Hardy, J. (1991) Segregation of a missense mutation in the amyloid precursor protein gene with familial Alzheimer's disease. Nature, 349, 704-706.
14. Hendriks, L., van Duijn, C.M., Cras, P., Cruts, M., van Hul, W., van Harskamp, F., Warren, A., Mcinnis, M.G., Antonarakis, S.E., Martin, J.J., Hofman, A. and van Broeckhoven, C. (1992) Presenile dementia and cerebral haemorrhage linked to a mutation at codon 692 of the beta-amyloid precursor protein gene. Nature Genet., 1, 218-221.
15. Jones, C.T., Morris, S., Yates, C.M., Moffoot, A., Sharpe, C., Brock, D.J.H. and St.Clair, D. (1992) Mutation in codon 713 of the β-amyloid precursor protein gene presenting with schizophrenia. Nature Genet. 1, 306-309.
16. Tanzi, R.E., Vaula, G., Romano, D.M., Mortilla, M., Huang, T.L., Tupler, R.G., Wasco, W., Hyman, B.T., Haines, J.L., Jenkins, B.J., Kalaitsidaki, M., Warren, A.C., Mcinnis, M.C., Antonarakis, S.E., Karlinsky, H., Percy, M.E., Connor, L., Growdon, J., Crapper-McLachlan, D.R., Gusella, J.F. and St George-Hyslop, P.H. (1992) Assessment of amyloid beta-protein precursor gene mutations in a large set of familial and sporadic Alzheimer disease cases. Am. J. Hum. Genet., 51, 273-282.
17. Kösel, S., Lücking, C.B., Egensperger, R., and Graeber, M.B. (1996) Non-radioactive PCR sequencing using digoxigenin. In Rapley R (ed) PCR Sequencing Protocols, Methods in Molecular Biology, Humana Press, Totowa, NJ, Vol. 65: 81-89
18. Hoff, P. (1991) Alzheimer and his time. In G.E. Berrios, H.L. Freeman (eds.), Eponymists in Medicine: Alzheimer and the dementias. Royal Society of Medicine Services Limited.
19. Fischer, O. (1907) Miliare Nekrosen mit drusigen Wucherungen der Neurofibrillen, eine regelmässige Veränderung der Hirnrinde bei seniler Demenz. Monatsschr. f. Psychiatr. Neurol., 22, 361-372.
20. Terry, R.D., Hansen, L.A., Deteresa, R., Davies, P., Tobias, H. and Katzman, R. (1987) Senile dementia of the Alzheimer type without neocortical neurofibrillary tangles. J. Neuropathol. Exp. Neurol. 46, 262-268.
21. Hansen, L.A., Masliah, E., Galasko, D. and Terry, R.D. (1993) Plaque-only Alzheimer's disease is usually the Lewy body variant, and vice versa. J. Neuropathol. Exp. Neurol. 52, 648-654.
22. Saunders, A.M., Strittmatter, W.J., Schmechel, D., St. George-Hyslop, P.H.S., Pencak-Vance, M.A., Joo, S.H., Rosi, B.L., Gusella, J.F., Crapper-McLachlan, D.R., Alberts, M.J., Hulette, C., Grain, B., Goldgaber, D. and Roses, A.D. (1993) Association of apolipoprotein E allele epsilon-4 with late-onset familial and sporadic alzheimers disease. Neurology 43, 1467-1472.
23. Corder, E.H., Saunders, A.M., Strittmatter, W.J., Schmechel, D.E., Gaskell, P.C., Small, G.W, Roses, A.D., Haines, J.L. and Pericak-Vance, M.A. (1993) Gene dose of apolipoprotein-E type-4 allele and the risk of Alzheimer's disease in late onset families. Science, 261, 921-923.
24. Lippa, C.F., Saunders, A.M., Smith, T.W., Swearer, J.M., Drachman, D.A., Ghetti, B., Nee, L., Pulaskisalo, D., Dickson, D., Robitaille, Y., Bergeron, C., Crain, B., Benson, M.D., Farlow, M., Hyman, B.T., St. George-Hyslop, P., Roses, A.D. and Pollen, D.A. (1996) Familial and sporadic Alzheimer's disease: Neuropathology cannot exclude a final common pathway. Neurology, 46, 406-412.
25. Sherrington, R., Rogaev, E.I., Liang, Y., Rogaeva, E.A., Levesque, G., Ikeda, M., Chi, H., Lin, C., Li, G., Holman, K., Tsuda, T., Mar, L., Foncin, J.F., Bruni, A.C., Montesi, M.P., Sorbi, S., Rainero, I., Pinessi, L., Nee, L., Chumakov, I., Pollen, D., Brookes, A., Sanseau, P., Polinsky, R.J., Wasco, W., Dasilva, H.A.R., Haines, J.L., Pericak-Vance, M.A., Tanzi, R.E., Roses, A.D., Fraser, P.E., Rommens, J.M. and St George-Hyslop, P.H. (1995) Cloning of a gene bearing missense mutations in early-onset familial Alzheimer's disease. Nature, 375, 754-760.
26. Levy-Lahad, E., Wasco, W., Poorkaj, P., Romano, D.M., Oshima, J., Pettingell, W.H., Yu, C.E., Jondro, P.D., Schmidt, S.D., Wang, K., Crowley, A.C., Fu, Y.H., Guenette, S.Y., Galas, D., Nemens, E., Wijsman, E.M., Bird, T.D., Schellenberg, G.D. and Tanzi, R.E. (1995) Candidate gene for the chromosome 1 familial Alzheimer's disease locus. Science, 269, 973-977.
27. Rogaev, E.I., Sherrington, R., Rogaeva, E.A., Levesque, G., Ikeda, M., Liang, Y., Chi, H., Lin, C., Holman, K., Tsuda, T., Mar, L., Sorbi, S., Nacmias, B., Piacentini, S., Amaducci, L., Chumakov, I., Cohen, D., Lannfelt, L., Fraser, P.E., Rommens, J.M. and St George-Hyslop, P.H. (1995) Familial Alzheimer's disease in kindreds with missense mutations in a gene on chromosome 1 related to the Alzheimer's disease type 3 gene. Nature, 376, 775-778.
28. Citron, M., Westaway, D., Xia, W., Carlson, G., Diehl, T., Levesque, G., Johnson-Wood, K., Lee, M., Seubert, P., Davis, A., Kholodenko, D., Motter, R., Sherrington, R., Perry, B., Yao, H., Strome, R., Lieberburg, I., Rommens, J., Kim, S., Schenk, D., Fraser, P., St. George-Hyslop, P. and Selkoe, D.J. (1997) Mutant presenilins of Alzheimer's disease increase production of 42-residue amyloid beta-protein in both transfected cells and transgenic mice. Nature Med., 3, 67-72.
29. Roses, A.D. (1996) The Alzheimer diseases. Curr. Opinion Neurobiol., 6, 644-650.
30. Graeber, M.B., Kösel, S., Egensperger, R., Schnopp, N.M., Bise, K. and Mehraein, P. (1995) Strategies for using archival brain tissue in neurogenetic research. J. Neuropathol. Exp. Neurol., 54, S27-S28.
31. Meyer, J.E. (1961) Alois Alzheimer. In Scholz, W. (ed.) 50 Jahre Neuropathologie in Deutschland. Thieme, Stuttgart.