Separation and characterization of clindamycin and related impurities in bulk drug by high-performance liquid chromatography-electrospray tandem mass spectrometry

Journal of Pharmaceutical and Biomedical Analysis

Volumn 41, Issue 4, 2006, Pages 1116-1123

  Zhou, Hui ^a   Zheng, Zhiguo ^c   Wu, Shihua ^b   Tai, Yuanpo ^c   Cao, Xiaoji ^c   Pan, Yuanjiang ^c  

^a ZHEJIANG UNIVERSITY   (China)

^b ZHEJIANG UNIVERSITY   (China)

^c ZHEJIANG UNIVERSITY   (China)

Author keywords

Clindamycin; HPLC; Impurities; Lincosamide; Tandem mass spectrometry

Indexed keywords

1 METHYLPYRROLE; 7 EPICLINDAMYCIN; ANTIBIOTIC AGENT; CLINDAMYCIN; CLINDAMYCIN B; DEHYDROCLINDAMYCIN; LINCOSAMIDE; METHANETHIOL; PROPANE; UNCLASSIFIED DRUG; WATER; ANTIINFECTIVE AGENT;

ARTICLE; COLLISIONALLY ACTIVATED DISSOCIATION; DRUG IDENTIFICATION; ELECTROSPRAY MASS SPECTROMETRY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; ION CYCLOTRON RESONANCE MASS SPECTROMETRY; PRIORITY JOURNAL; CHEMISTRY; DRUG CONTAMINATION; METHODOLOGY;

ANTI-BACTERIAL AGENTS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CLINDAMYCIN; DRUG CONTAMINATION; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION;

EID: 33746653845     PISSN: 07317085     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jpba.2006.02.014     Document Type: Article

References (27)

1. Stevens H.A. Prim. Care Update Ob/Gyns 4 (1997) 251-253
2. Birkenmeyer R.D., and Kagan F. J. Med. Chem. 13 (1970) 616-619
3. Landis J.B., Grant M.E., and Nelson S.A. J. Chromatogr. 202 (1980) 99-106
4. Brodasky T.F., and Lewis C. J. Antibiot. 25 (1972) 230-238
5. El-Yazbi F.A., and Blaih S.M. Analyst 118 (1993) 577-579
6. Duckworth C., Fisher J.F., Carter S.A., Newman C.L., Cogburn C., Nesbit R.R., and Wray C.H. J. Antimicrob. Agents Chemother. 31 (1993) 581
7. Gatti G., Flaherty J., Bubp J., White J., Borin M., and Gambertoglio J. J. Antimicrob. Agents Chemother. 37 (1993) 1137
8. Brown L.W. J. Pharm. Sci. 63 (1974) 1597-1600
9. Oesterling T.O. J. Pharm. Sci. 59 (1970) 63-67
10. P. Dehouck, A. Van Schepdael, E. Roets, J. Hoogmartens, J. Chromatogr. A 9322001 1245-152.
11. Brown L.W. J. Pharm. Sci. 67 (1978) 1254-1257
12. La Follette G., Gambertoglio J., White J.A., Knuth D.W., and Lin E.T. J. Chromatogr. 431 (1988) 379-388
13. Hornedo-Nuñez A., Getek T.A., Korfmacher W.A., and Simenthal F. J. Chromatogr. 503 (1990) 217-225
14. Orwa J.A., Vandenbempt K., Depuydt S., Roets E., and Hoogmartens J. J. Pharm. Biomed. Anal. 20 (1999) 745-752
15. Orwa J.A., Vandenbempt K., Depuydt S., Roets E., and Hoogmartens J. J. Pharm. Biomed. Anal. 23 (2000) 771
16. Fieger-Büschges H., Schüβler G., Larsimont V., and Blume H. J. Chromatogr. B 724 (1999) 281-286
17. Cho S., Im H., Park W., Ha Y., Choi Y., and Lee K. Biomed. Chromatogr. 19 (2005) 783-787
18. Batzias G.C., Delis G.A., and Koutsoviti-Papadopoulou M. J. Pharm. Biomed. Anal. 35 (2004) 545-554
19. United States Pharmacopeia, 29, United States Pharmacopeial Convention, Inc., Rockville, Maryland, 2006, p. 536.
20. European Pharmacopoeia, Supplement 4.2 to fourth ed., Council of Europe, Strasbourg, France, 2002.
21. D.J. Platzer, B.A. White, J. Pharm. Biomed. Anal. 41 (2006) 84-88.
22. Martens-Lobenhoffer J., and Banditt P. J. Chromatogr. B 755 (2001) 143-149
23. Yu L., Chao C., Liao W., Twu T., Liu C., Yang T., and Lin E.T. J. Chromatogr. B 724 (1999) 287-294
24. Rechberger G.N., Fauler G., Windischhofer W., Köfeler H., Erwa W., and Leis H. Rapid Commun. Mass Spectrom. 17 (2003) 135-139
25. Cherlet M., Croubels S., and De Backer P. J. Mass Spectrom. 37 (2002) 848-853
26. Sin D.W.M., Ho C., Wong Y.C., Ho S.K., and Ip A.C.B. Anal. Chim. Acta 517 (2004) 39-45
27. The National Institute of Standards and Technology (NIST), Standard Reference Database Number 69, NIST Chemistry WebBook, available on http://webbook.nist.gov/chemistry/.