Investigations of the supercoil-selective DNA binding of wild type p53 suggest a novel mechanism for controlling p53 function

European Journal of Biochemistry

Volumn 271, Issue 19, 2004, Pages 3865-3876

  Fojta, Miroslav ^a   Pivonkova, Hana ^a   Brazdova, Marie ^a,b   Nemcova, Katerina ^a   Palecek, Jan ^a,c   Vojtesek, Borivoj ^d  

^a INSTITUTE OF BIOPHYSICS   (Czech Republic)

^b UNIVERSITY OF HAMBURG   (Germany)

^c UNIVERSITY OF SUSSEX   (United Kingdom)

^d MASARYK MEMORIAL CANCER INSTITUTE   (Czech Republic)

Author keywords

Monoclonal antibodies; p53 latency; Redox state; Supercoil selective DNA binding; Tumor suppressor protein p53

Indexed keywords

ANTIBODY; CIRCULAR DNA; CYSTEINE; DNA; EPITOPE; OLIGONUCLEOTIDE; PLASMID DNA; PROTEIN P53;

ARTICLE; BINDING SITE; CARBOXY TERMINAL DNA BINDING SITE; CARBOXY TERMINAL SEQUENCE; CONSENSUS SEQUENCE; CONTROLLED STUDY; DELETION MUTANT; DNA SUPERCOILING; HUMAN; NONHUMAN; OXIDATION; PRIORITY JOURNAL; PROTEIN DNA BINDING; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN FUNCTION; REGULATORY MECHANISM; STRESS;

ANTIBODIES, MONOCLONAL; BINDING SITES; BINDING SITES, ANTIBODY; DNA, SUPERHELICAL; HUMANS; MUTAGENESIS, SITE-DIRECTED; OXIDATION-REDUCTION; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; SEQUENCE DELETION; TUMOR SUPPRESSOR PROTEIN P53;

EID: 4944241898     PISSN: 00142956     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1432-1033.2004.04323.x     Document Type: Article

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