The nuclear matrix as a target for viral and cellular oncogenes

Critical Reviews in Eukaryotic Gene Expression

Volumn 10, Issue 1, 2000, Pages 45-61

  Deppert, Wolfgang ^a  

^a UNIVERSITY OF HAMBURG   (Germany)

Author keywords

Cell transformation; MAR element; p53; SV40 tumor antigen

Indexed keywords

TUMOR ANTIGEN;

CANCER; CARCINOGENESIS; CELL NUCLEUS MATRIX; CHROMATIN; NONHUMAN; ONCOGENE; PRIORITY JOURNAL; REVIEW; SIMIAN VIRUS 40;

SIMIAE; SIMIAN VIRUS; SIMIAN VIRUS 40; TUMOR VIRUS;

EID: 0034022694     PISSN: 10454403     EISSN: None     Source Type: Journal    
DOI: 10.1615/critreveukargeneexpr.v10.i1.70     Document Type: Review

References (64)

1. Alvarez-Salas LM, Velazquez A, Lopez-Bayghen E, Woodworth CD, Garrido E, Gariglio P, DiPaolo JA (1995): Transcriptional repression in normal human keratinocytes by wild-type and mutant p53. Cancer Lett 91:85-92.
2. Belgrader P, Siegel AJ, Berezney R (1991): A comprehensive study on the isolation and characterization of the HeLa S3 nuclear matrix. J Cell Sci 98:281-291.
3. Berezney R (1991): The nuclear matrix: a heuristic model for investigating genomic organization and function in the cell nucleus. J Cell Biochem 47:109-123.
4. Berezney R, Wei XY (1998): The new paradigm: Integrating genomic function and nuclear architecture. J Cell Biochem 30-31(Suppl):238-242.
5. Bode J, Kohwi Y, Dickinson L, Joh T, Klehr D, Mielke C, Kohwi-Shigematsu T (1992): Biological significance of unwinding capability of nuclear matrix-associating DNAs. Science 255:195-197.
6. Butel JS, Lednicky JA (1999): Cell and molecular biology of simian virus 40: Implications for human infections and disease. J Natl Cancer Inst 91:119-134.
7. Carvalho T, Seeler JS, Ohman K, Jordan P, Pettersson U, Akusjarvi G, Carmo-Fonseca M, Dejean A (1995): Targeting of adenovirus E1A and E4-ORF3 proteins to nuclear matrix-associated PML bodies. J Cell Biol 131:45-56.
8. Cellular and Molecular Life Sciences (1999) 51(1).
9. Chin KV, Ueda K, Pastan I, Gottesman MM (1992): Modulation of activity of the promoter of the human MDR1 gene by ras and p53. Science 255:459-462.
10. Cockerill PN, Yuen M-H, Garrard WT (1987): The enhancer of the immunglubulin heavy chain locus is flanked by presumptive chromosomal loop anchorage elements. J Biol Chem 262:5394-5397.
11. Deppert W, Steinmeyer M (1986): Distinct domains of simian virus 40 large T antigen mediate its association with different cellular targets. In Peters R, Trendelenburg M (eds): "Nucleocytoplasmatic Transport", pp. 199-214, Berlin, Heidelberg: Springer Verlag.
12. Deppert W, Haug M (1986): Evidence for free and metabolically stable p53 protein in nuclear subfractions of simian virus 40-transformed cells. Mol Cell Biol 6:2233-2240.
13. Deppert W, Steinmayer T, Richter W (1989): Cooperation of SV40 large T antigen and the cellular protein p53 in maintenance of transformation. Oncogene 4:1103-1110.
14. Deppert W, von der Weth A (1990): Functional interaction of nuclear transport-defective simian virus 40 large T antigen with chromatin and nuclear matrix. J Virol 64:838-846.
15. Deppert W, Kurth M, Graessmann M, Graessmann A, Knippschild U (1991): Altered phosphorylation at specific sites confers a mutant phenotype to SV40 wild-type large T antigen in a flat revenant of SV40 transformed cells. Oncogene 6:1931-1938.
16. Deppert W (1994): The yin and yang of p53 in cellular proliferation. Cancer Biol 5:187-202.
17. Deppert W, Schirmbeck R (1995): The nuclear matrix and virus function. Int Rev Cytol 162A:486-537.
18. Dickinson LA, Dickinson CD, Kohwi-Shigematsu T (1997): An atypical homeodomain in SATB1 promotes specific recognition of the key structural element in a matrix attachment region. J Biol Chem 272:11463-11470.
19. Dittmer D, Pati S, Zambetti G, Chu S, Teresky AK, Moore M, Finlay C, Levine AJ (1993): Gain of function mutations in p53. Nat Genet 4:42-46.
20. Fischer AH, Chadee DN, Wright JA, Gansler TS, Davie JR (1998): Ras-associated nuclear structural change appears functionally significant and independent of the mitotic signaling pathway. J Cell Biochem 70:130-140.
21. Herbomel P (1990): From gene to chromosome: organisation levels defined by the interplay of transcription and replication in vertebrates. New Biol 39:937-945.
22. Hinds P, Finlay C, Levine AJ (1989): Mutation is required to activate the p53 gene for cooperation with the ras oncogene and transformation. J Virol 63:739-746.
23. Hinzpeter M, Deppert W (1987): Analysis of biological and biochemical parameters for chromatin and nuclear matrix association of SV 40 large T antigen in transformed cells. Oncogene 1:119-129.
24. Holth LT, Chadee DN, Spencer VA, Samuel SK, Safneck JR, Davie JR (1998): Chromatin, nuclear matrix and the cytoskeleton: role of cell structure in neoplastic transformation (review). Int J Oncol 13:827-837.
25. Keesee SK, Briggman JV, Thill G, Wu YJ (1996): Utilization of nuclear matrix proteins for cancer diagnosis. Crit Rev Eukaryot Gene Expr 6:189-214.
26. Kieser A, Weich HA, Brandner G, Marme D, Kolch W (1994): Mutant p53 potentiates protein kinase C induction of vascular endothelial growth factor expression. Oncogene 9:963-969.
27. Klehr D, Maass K, Bode J (1991): Scaffold-attached regions from the human interferon β domain can be used to enhance the stable expression of genes under the control of various promoters. Biochemistry 30:1264-1270.
28. Knippschild U, Kiefer J, Patschinsky T, Deppert W (1991): Phenotype-specific phosphorylation of simian virus 40 tsA mutant large T antigens in tsA N-type and A-type transformants. J Virol 65:4414-4423.
29. Lane DPSimanis V, Bartsch R, Yewdell J, Gannon J, Mole S (1985): Cellular targets for SV40 large T-antigen. Proc R Soc Lond B 226:25-41.
30. Lin J, Teresky AK, Levine AJ (1995): Two critical hydrophobic amino acids in the N-terminal domain of the p53 protein are required for the gain of function phenotypes of human p53 mutants. Oncogene 10:2387-2390.
31. Malyapa RS, Wright WD, Taylor YC, Roti Roti JL (1996): DNA supercoiling changes and nuclear matrix-associated proteins: possible role in oncogene-mediated radioresistance. Int J Radiat Oncol Biol Phys 35:963-973.
32. Mielke C, Maas K, Tümmler M, Bode J (1996): Anatomy of highly expressing chromosomal sites targeted by retroviral vectors. Biochemistry 35:2239-2252.
33. Milner J, Medcalf EA (1991): Cotranslation of activated mutant p53 with wild type drives the wild-type p53 protein into the mutant conformation. Cell 65:765-774.
34. Müller BF, Paulsen D, Deppert W (1996): Specific binding of MAR/SAR DNA-elements by mutant p53. Oncogene 12:1941-1952.
35. Nickerson JA, Penman S (1991): Bio Vision: microscopy in three dimensions. Semin Cell Biol 2:117-129.
36. Peled A, Zipori D, Rotter V (1996): Cooperation between p53-dependent and p53-independent apoptotic pathways in myeloid cells. Cancer Res 56:2148-2156.
37. Phi-Van L, Strätling WH (1990): Association of DNA with nuclear matrix. Prog Mol Subcell Biol 11:1-11.
38. Piechaczek C, Fetzer C, Baiker A, Bode J, Lipps HJ (1999): A vector based on the SV40 origin of replication and chromosomal S/MARs replicates episomally in CHO cells. Nucl Acids Res 27:426-428.
39. Pohl J, Goldfinger N, Radler-Pohl A, Rotter V, Schirrmacher V (1988): p53 increases experimental metastatic capacity of murine carcinoma cells. Mol Cell Biol 8:2078-2081.
40. Polack A, Strobls L, Feederle R, Schweizer M, Koch E, Eick D, Wiegand H, Bornkamm GW (1991): The intron enhancer of the immunoglobulin kappa gene activates c-myc but does not induce the Burkitt-specific promoter shift. Oncogene 6:2033-2040.
41. Poljak L, Seum C, Mattioni T, Laemmli UK (1994): SARs stimulate but do not confer position independent gene expression. Nucl Acid Res 22:4386-4394.
42. Prives C (1990): The replication functions of SV40 T antigen are regulated by phosphorylation. Cell 61:735-738.
43. Roemer K (1999): Mutant p53: gain-of-function oncoproteins and wild-type p53. Biol Chem 380:879-887.
44. Samuel SK, Minish TM, Davie R. (1997): Altered nuclear matrix protein profiles in oncogene-transformed mouse fibroblasts exhibiting high metastatic potential. Cancer Res 57:147-151.
45. Schirmbeck R, Deppert W (1989): Nuclear subcompartmentalization of simian virus 40 large T antigen: evidence for in vivo regulation of biochemical activities. J Virol 63:2308-2316.
46. Shaulsky G, Goldfinger N, Rotter V (1991): Alterations in tumor development in vivo mediated by expression of wild type or mutant p53 proteins. Cancer Res 51:5232-5237.
47. Stacy TP, Chamberlain M, Carswell S, Cole CN (1990): The growth of simian virus 40 (SV40) host range/adenovirus helper function mutants in an African green monkey cell line that constitutively expresses the SV40 agnoprotein. J Virol 64:3522-3526.
48. Staufenbiel M, Deppert W (1982): Intermediate filament systems are collapsed onto the nuclear surface after isolation of nuclei from tissue culture cells. Exp Cell Res 138:207-214.
49. Staufenbiel M, Deppert W (1983a): Nuclear matrix preparations from liver tissue and from cultured vertebrate cells: differences in major polypeptides. Eur J Cell Biol 31:341-348.
50. Staufenbiel M, Deppert W (1983b): Different structural systems of the nucleus are targets for SV40 large T antigen. Cell 33:173-181.
51. Staufenbiel, M, Deppert W (1984): Preparation of nuclear matrices from cultured cells: Subfractionation of nuclei in situ. J Cell Biol 98:1886-1894.
52. Steinmeyer K, Deppert W (1988): DNA binding properties of murine p53. Oncogene 3:501-507.
53. Steinmeyer K (1989): Ph.D. thesis: Charakterisierung nukleärer Subklassen des zellulären Tumorantigens p53. Universität Ulm.
54. Stief A, Winter DM, Strätling WH, Sippel AE (1989): A nuclear DNA attachment element mediates elevated and position-independent gene activity. Nature 341:343-345.
55. Subler MA, Martin DW, Deb S (1994): Overlapping domains on the p53 protein regulate its transcriptional activation and repression functions. Oncogene 9:1351-1359.
56. Tiemann F, Deppert W (1994): Stabilization of the tumor suppressor p53 during cellular transformation by simian virus 40: Influence of viral and cellular factors, and biological consequences. J Virol 68:2869-2878.
57. Tiemann F, Zerrahn J, Deppert W (1995): Cooperation of simian virus 40 large and small T antigens in metabolic stabilization of tumor suppressor p53 during cellular transformation. J Virol 69:6115-6121.
58. Wang B, Dickinson LA, Koivunen E, Ruoslahti E, Kohwi-Shigematsu T (1995): A novel matrix attachment region DNA binding motif identified using a random phage peptide library. J Biol Chem 270:23239-23242.
59. Weißker S, Müller B, Homfeld A, Deppert W (1992): Specific and complex interactions of murine p53 with DNA. Oncogene 7:1921-1932.
60. Will K, Warnecke G, Albrechtsen N, Boulikas T, Deppert W (1998a): High-affinity MAR-DNA binding is a common property of murine and human mutant p53. J Cell Biochem 69:260-270.
61. Will K, Warnecke G, Wiesmüller L, Deppert W (1998b): Specific interaction of mutant p53 with regions of matrix attachment region DNA elements (MARs) with a high potential for base-unpairing. Proc Natl Acad Sci USA 95:13681-13686.
62. Zerrahn J, Deppert W, Weidemann D, Patschinsky T, Richards F, Milner J (1992): Correlation between the conformational phenotype of p53 and its subcellular location. Oncogene 7:1371-1381.
63. Zerrahn J, Deppert W (1993): Analysis of simian virus 40 small t antigen-induces progression of rat F111 cells minimally transformed by large T antigen. J Virol 67:1555-1563.
64. Zerrahn J, Tiemann F, Deppert W (1996): Simian virus 40 small T antigen activates the carboxy-terminal transforming p53-binding domain of large T antigen. J Virol 70:6781-6789.