Prediction of in vivo biliary clearance from the in vitro transcellular transport of organic anions across a double-transfected madin-darby canine kidney II monolayer expressing both rat organic anion transporting polypeptide 4 and multidrug resistance associated protein

Molecular Pharmacology

Volumn 66, Issue 3, 2004, Pages 450-459

  Sasaki, Makoto ^a   Suzuki, Hiroshi ^a   Aoki, Jun ^a   Ito, Kousei ^b   Meier, Peter J ^c   Sugiyama, Yuichi ^a  

^a UNIVERSITY OF TOKYO   (Japan)

^b CHIBA UNIVERSITY   (Japan)

^c UNIVERSITY HOSPITAL ZURICH   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLO(DEXTRO TRYPTOPHYL DEXTRO ASPARTYLPROLYL DEXTRO VALYLLEUCYL); ESTRADIOL 17 GLUCURONIDE; LEUKOTRIENE C4; METHOTREXATE; MULTIDRUG RESISTANCE PROTEIN 2; ORGANIC ANION TRANSPORTER; ORGANIC ANION TRANSPORTER 4; PRAVASTATIN; TAUROLITHOCHOLIC ACID; TEMOCAPRILAT; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; APICAL MEMBRANE; ARTICLE; BASOLATERAL MEMBRANE; BILIARY EXCRETION; CELL STRAIN; COMPARATIVE STUDY; CONTROLLED STUDY; DNA TRANSFECTION; DRUG CLEARANCE; DRUG UPTAKE; IN VITRO STUDY; IN VIVO STUDY; MALE; MONOLAYER CULTURE; NONHUMAN; PREDICTION; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; RAT; TRANSCYTOSIS; TRANSPORT KINETICS;

ANIMALS; ANIONS; BILIARY TRACT; BIOLOGICAL TRANSPORT; CELLS, CULTURED; DOGS; HUMANS; MEMBRANE TRANSPORT PROTEINS; METABOLIC CLEARANCE RATE; MULTIDRUG RESISTANCE-ASSOCIATED PROTEINS; ORGANIC ANION TRANSPORTERS, SODIUM-INDEPENDENT; RATS; TRANSFECTION;

EID: 4944225107     PISSN: 0026895X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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