Central venous catheter-associated infections

Best Practice and Research: Clinical Anaesthesiology

Volumn 22, Issue 3, 2008, Pages 407-421

  Zingg, Walter ^a   Cartier Fässler, Vanessa ^a   Walder, Bernhard ^a  

^a GENEVA UNIVERSITY HOSPITALS   (Switzerland)

Author keywords

anesthesia; bloodstream infections; central venous catheters; critical care; infectious diseases

Indexed keywords

ANTIBIOTIC AGENT; CHLORHEXIDINE GLUCONATE; HEPARIN; MINOCYCLINE; POVIDONE IODINE; RIFAMPICIN; UROKINASE;

ANTISEPSIS; BLOOD CULTURE; BLOOD DISEASE; CATHETER INFECTION; CATHETER REMOVAL; CATHETER THROMBOSIS; CENTRAL VENOUS CATHETER; CENTRAL VENOUS CATHETERIZATION; CLINICAL TRIAL; CONTINUOUS INFUSION; COST EFFECTIVENESS ANALYSIS; DIAGNOSTIC TEST; DISEASE SURVEILLANCE; GEOGRAPHIC DISTRIBUTION; HAND WASHING; HEALTH CARE COST; HIGH RISK POPULATION; HOSPITAL HYGIENE; HUMAN; INFECTION PREVENTION; INFECTION RATE; INFECTION RISK; INTENSIVE CARE UNIT; MATERIAL COATING; OUTCOME ASSESSMENT; PARENTERAL NUTRITION; PRIORITY JOURNAL; REVIEW; RISK FACTOR; VASCULAR ACCESS; WARD;

CATHETER-RELATED INFECTIONS; CATHETERIZATION, CENTRAL VENOUS; CRITICAL CARE; HUMANS; RISK FACTORS;

EID: 49349110987     PISSN: 15216896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bpa.2008.05.007     Document Type: Review

References (99)

1. Goldmann D.A., and Maki D.G. Infection control in total parenteral nutrition. JAMA : The Journal of the American Medical Association 223 (1973) 1360-1364
2. Maki D.G., Goldman D.A., and Rhame F.S. Infection control in intravenous therapy. Annals of Internal Medicine 79 (1973) 867-887
3. Maki D.G., Kluger D.M., and Crnich C.J. The risk of bloodstream infection in adults with different intravascular devices: a systematic review of 200 published prospective studies. Mayo Clinic Proceedings 81 (2006) 1159-1171
4. Lorente L., Villegas J., Martin M.M., et al. Catheter-related infection in critically ill patients. Intensive Care Medicine 30 (2004) 1681-1684
5. Jean G., Charra B., Chazot C., et al. Risk factor analysis for long-term tunneled dialysis catheter-related bacteremias. Nephron 91 (2002) 399-405
6. Kuizon D., Gordon S.M., and Dolmatch B.L. Single-lumen subcutaneous ports inserted by interventional radiologists in patients undergoing chemotherapy: incidence of infection and outcome of attempted catheter salvage. Annals of Internal Medicine 161 (2001) 406-410
7. Mermel L.A. Prevention of intravascular catheter-related infections. Annals of Internal Medicine 132 (2000) 391-402
8. Coello R., Charlett A., Ward V., et al. Device-related sourcesw of bacteraemia in English hospitals-opportunities for the prevention of hospital-acquierd bacteraemia. The Journal of Hospital Infection 53 (2003) 46-57
9. National Nosocomial Infections Surveillance (NNIS) System Report, data summary from January 1992 through June 2004, issued October 2004. American Journal of Infection Control 32 (2004) 470-485
10. Aubaniac R. Subclavian intravenous injection; advantages and technic. Presse Med 60 (1952) 1456
11. Mostert J.W., Kenny G.M., and Murphy G.P. Safe placement of central venous catheter into internal jugular veins. Archives of Surgery (Chicago, Ill. : 1960) 101 (1970) 431-432
12. Peters J.L., Mehtar S., Vallis C.J., and Kenning B.R. Central venous catheter design and maintenance complications. British Journal of Anaesthesia 51 (1979) 805-806
13. Pottecher T., Forrler M., Picardat P., et al. Thrombogenicity of central venous catheters: prospective study of polyethylene, silicone and polyurethane catheters with phlebography or post-mortem examination. European Journal of Anaesthesiology 1 (1984) 361-365
14. Hecker J.F., and Scandrett L.A. Roughness and thrombogenicity of the outer surface of intravascular catheters. Journal of Biomedical Materials Research 19 (1985) 381-395
15. Garner J.S., Jarvis W.R., Emori T.G., et al. CDC definitions for nosocomial infections, 1988. American Journal of Infection Control 16 (1988) 128-140
16. O'Grady N.P., Alexander M., Dellinger E.P., et al. Guidelines for the prevention of intravascular catheter-related infections. Centers for Disease Control and Prevention. MMWR Recommendations and Reports 51 (2002) 1-29
17. Seo S.K., Venkataraman L., DeGirolami P.C., and Samore M.H. Molecular typing of coagulase-negative staphylococci from blood cultures does not correlate with clinical criteria for true bacteremia. The American Journal of Medicine 109 (2000) 697-704
18. Casey A.L., Worthington T., Lambert P.A., and Elliott T.S. Evaluation of routine microbiological techniques for establishing the diagnosis of catheter-related bloodstream infection caused by coagulase-negative staphylococci. Journal of Medical Microbiology 56 (2007) 172-176
19. Edwards J.R., Peterson K.D., Andrus M.L., et al. National Healthcare Safety Network (NHSN) Report, data summary for 2006, issued June 2007. American Journal of Infection Control 35 (2007) 290-301
20. Vonberg R.P., Behnke M., Geffers C., et al. Device-associated infection rates for non-intensive care unit patients. Infection Control and Hospital Epidemiology 27 (2006) 357-361
21. Marschall J., Leone C., Jones M., et al. Catheter-associated bloodstream infections in general medical patients outside the intensive care unit: a surveillance study. Infection Control and Hospital Epidemiology 28 (2007) 905-909
22. Rosenthal V.D., Maki D.G., Salomao R., et al. Device-associated nosocomial infections in 55 intensive care units of 8 developing countries. Annals of Internal Medicine 145 (2006) 582-591
23. Mehta A., and Rosenthal V.D. Device-associated nosocomial infection rates in intensive care units of seven Indian cities. Findings of the International Nosocomial Infection Control Consortium (INICC). The Journal of Hospital Infection 67 (2007) 168-174
24. Lobo R.D., Levin A.S., Gomes L.M., et al. Impact of an educational program and policy changes on decreasing catheter-associated bloodstream infections in a medical intensive care unit in Brazil. American Journal of Infection Control 33 (2005) 83-87
25. Ramirez Barba E.J., Rosenthal V.D., Higuera F., et al. Device-associated nosocomial infection rates in intensive care units in four Mexican public hospitals. American Journal of Infection Control 34 (2006) 244-247
26. Rosenthal V.D., Guzman S., and Crnich C. Device-associated nosocomial infection rates in intensive care units of Argentina. Infection Control and Hospital Epidemiology 25 (2004) 251-255
27. Moreno C.A., Rosenthal V.D., Olarte N., et al. Device-associated infection rate and mortality in intensive care units of 9 Colombian hospitals: findings of the International Nosocomial Infection Control Consortium. Infection Control and Hospital Epidemiology 27 (2006) 349-356
28. Richet H., Hubert B., Nitemberg G., et al. Prospective multicenter study of vascular-catheter-related complications and risk factors for positive central-catheter cultures in intensive care unit patients. Journal of Clinical Microbiology 28 (1990) 2520-2525
29. Moro M.L., Vigano E.F., and Cozzi Lepri A. Risk factors for central venous catheter-related infections in surgical and intensive care units. The Central Venous Catheter-Related Infections Study Group. Infection Control and Hospital Epidemiology 15 (1994) 253-264
30. Adler A., Yaniv I., Steinberg R., et al. Infectious complications of implantable ports and Hickman catheters in paediatric haematology-oncology patients. The Journal of Hospital Infection 62 (2006) 358-365
31. Rijnders B.J., Van Wijngaerden E., Vandecasteele S.J., et al. Treatment of long-term intravascular catheter-related bacteraemia with antibiotic lock: randomized, placebo-controlled trial. The Journal of Antimicrobial Chemotherapy 55 (2005) 90-94
32. Goetz A.M., Wagener M.M., Miller J.M., and Muder R.R. Risk of infection due to central venous catheters: effect of site of placement and catheter type. Infection Control and Hospital Epidemiology 19 (1998) 842-845
33. Merrer J., De Jonghe B., Golliot F., et al. Complications of femoral and subclavian venous catheterization in critically ill patients: a randomized controlled trial. JAMA : The Journal of the American Medical Association 286 (2001) 700-707
34. Ruesch S., Walder B., and Tramer M.R. Complications of central venous catheters: internal jugular versus subclavian access-a systematic review. Critical Care Medicine 30 (2002) 454-460
35. Cobb D.K., High K.P., Sawyer R.G., et al. A controlled trial of scheduled replacement of central venous and pulmonary-artery catheters. The New England Journal of Medicine 327 (1992) 1062-1068
36. Yilmaz G., Koksal I., Aydin K., et al. Risk factors of catheter-related bloodstream infections in parenteral nutrition catheterization. JPEN. Journal of Parenteral and Enteral Nutrition 31 (2007) 284-287
37. Opilla M.T., Kirby D.F., and Edmond M.B. Use of ethanol lock therapy to reduce the incidence of catheter-related bloodstream infections in home parenteral nutrition patients. JPEN. Journal of Parenteral and Enteral Nutrition 31 (2007) 302-305
38. Melly M.A., Meng H.C., and Schaffner W. Microbiol growth in lipid emulsions used in parenteral nutrition. Archives of Surgery (Chicago, Ill. : 1960) 110 (1975) 1479-1481
39. Zurcher M., Tramer M.R., and Walder B. Colonization and bloodstream infection with single- versus multi-lumen central venous catheters: a quantitative systematic review. Anesthesia and Analgesia 99 (2004) 177-182
40. Timsit J.F., Farkas J.C., Boyer J.M., et al. Central vein catheter-related thrombosis in intensive care patients: incidence, risks factors, and relationship with catheter-related sepsis. Chest 114 (1998) 207-213
41. Robert J., Fridkin S.K., Blumberg H.M., et al. The influence of the composition of the nursing staff on primary bloodstream infection rates in a surgical intensive care unit. Infection Control and Hospital Epidemiology 21 (2000) 12-17
42. Hugonnet S., Chevrolet J.C., and Pittet D. The effect of workload on infection risk in critically ill patients. Critical Care Medicine 35 (2007) 76-81
43. Maki D.G., Ringer M., and Alvarado C.J. Prospective randomised trial of povidone-iodine, alcohol, and chlorhexidine for prevention of infection associated with central venous and arterial catheters. Lancet 338 (1991) 339-343
44. Mimoz O., Pieroni L., Lawrence C., et al. Prospective, randomized trial of two antiseptic solutions for prevention of central venous or arterial catheter colonization and infection in intensive care unit patients. Critical Care Medicine 24 (1996) 1818-1823
45. Karakitsos D., Labropoulos N., De Groot E., et al. Real-time ultrasound-guided catheterisation of the internal jugular vein: a prospective comparison with the landmark technique in critical care patients. Critical Care (London, England) 10 (2006) R162
46. Gastmeier P., Menzel K., Sohr D., and Ruden H. Usefulness of severity-of-illness scores based on admission data only in nosocomial infection surveillance systems. Infection Control and Hospital Epidemiology 28 (2007) 453-458
47. Richards M.J., Edwards J.R., Culver D.H., and Gaynes R.P. Nosocomial infections in pediatric intensive care units in the United States. National Nosocomial Infections Surveillance System. Pediatrics 103 (1999) e39
48. Elward A.M., and Fraser V.J. Risk factors for nosocomial primary bloodstream infection in pediatric intensive care unit patients: a 2-year prospective cohort study. Infection Control and Hospital Epidemiology 27 (2006) 553-560
49. Aly H., Herson V., Duncan A., et al. Is bloodstream infection preventable among premature infants? A tale of two cities. Pediatrics 115 (2005) 1513-1518
50. Geffers C., Baerwolff S., Schwab F., and Gastmeier P. Incidence of healthcare-associated infections in high-risk neonates: results from the German surveillance system for very-low-birthweight infants. The Journal of Hospital Infection 68 (2008) 214-221
51. Safdar N., and Maki D.G. Inflammation at the insertion site is not predictive of catheter-related bloodstream infection with short-term, noncuffed central venous catheters. Critical Care Medicine 30 (2002) 2632-2635
52. Safdar N., Fine J.P., and Maki D.G. Meta-analysis: methods for diagnosing intravascular device-related bloodstream infection. Annals of Internal Medicine 142 (2005) 451-466
53. Maki D.G., Weise C.E., and Sarafin H.W. A semiquantitative culture method for identifying intravenous-catheter-related infection. The New England Journal of Medicine 296 (1977) 1305-1309
54. Cleri D.J., Corrado M.L., and Seligman S.J. Quantitative culture of intravenous catheters and other intravascular inserts. The Journal of Infectious Diseases 141 6 (1980 Jun) 781-786
55. Brun Buisson C., Rauss A., and Legrand P. Semiquantitative culture of catheter tips. Journal of Clinical Microbiology 25 (1987) 1343-1344
56. Sherertz R.J., Raad I.I., Belani A., et al. Three-year experience with sonicated vascular catheter cultures in a clinical microbiology laboratory. Journal of Clinical Microbiology 28 (1990) 76-82
57. Raad I.I., Sabbagh M.F., Rand K.H., and Sherertz R.J. Quantitative tip culture methods and the diagnosis of central venous catheter-related infections. Diagnostic Microbiology and Infectious Disease 15 (1992) 13-20
58. Brun-Buisson C., Abrouk F., Legrand P., et al. Diagnosis of central venous catheter-related sepsis. Critical level of quantitative tip cultures. Archives of Internal Medicine 147 (1987) 873-877
59. Gowardman J.R., Montgomery C., Thirlwell S., et al. Central venous catheter-related bloodstream infections: an analysis of incidence and risk factors in a cohort of 400 patients. Intensive Care Medicine 24 (1998) 1034-1039
60. Ekkelenkamp M.B., van der Bruggen T., van de Vijver D.A., et al. Bacteremic complications of intravascular catheters colonized with Staphylococcus aureus. Clinical Infectious Diseases 46 (2008) 114-118
61. Coutlee F., Lemieux C., and Paradis J.F. Value of direct catheter staining in the diagnosis of intravascular-catheter-related infection. Journal of Clinical Microbiology 26 (1988) 1088-1090
62. Zufferey J., Rime B., Francioli P., and Bille J. Simple method for rapid diagnosis of catheter-associated infection by direct acridine orange staining of catheter tips. Journal of Clinical Microbiology 26 (1988) 175-177
63. Capdevila J.A., Planes A.M., Palomar M., et al. Value of differential quantitative blood cultures in the diagnosis of catheter-related sepsis. European Journal of Clinical Microbiology & Infectious Diseases 11 (1992) 403-407
64. Siegman-Igra Y., Anglim A.M., Shapiro D.E., et al. Diagnosis of vascular catheter-related bloodstream infection: a meta-analysis. Journal of Clinical Microbiology 35 (1997) 928-936
65. Blot F., Nitenberg G., Chachaty E., et al. Diagnosis of catheter-related bacteraemia: a prospective comparison of the time to positivity of hub-blood versus peripheral-blood cultures. Lancet 354 (1999) 1071-1077
66. Raad I., Hanna H.A., Alakech B., et al. Differential time to positivity: a useful method for diagnosing catheter-related bloodstream infections. Annals of Internal Medicine 140 (2004) 18-25
67. Guerti K., Ieven M., and Mahieu L. Diagnosis of catheter-related bloodstream infection in neonates: a study on the value of differential time to positivity of paired blood cultures. Pediatric Critical Care Medicine 8 (2007) 470-475
68. Shah S.S., Downes K.J., Elliott M.R., et al. How long does it take to "rule out" bacteremia in children with central venous catheters?. Pediatrics 121 (2008) 135-141
69. Rushforth J.A., Hoy C.M., Kite P., and Puntis J.W. Rapid diagnosis of central venous catheter sepsis. Lancet 342 (1993) 402-403
70. Kite P., Dobbins B.M., Wilcox M.H., and McMahon M.J. Rapid diagnosis of central-venous-catheter-related bloodstream infection without catheter removal. Lancet 354 (1999) 1504-1507
71. Millar M.R., Johnson G., Wilks M., et al. Molecular diagnosis of vascular access device-associated infection in children being treated for cancer or leukaemia. Clinical Microbiology and Infection 14 (2008) 213-220
72. Blot S.I., Depuydt P., Annemans L., et al. Clinical and economic outcomes in critically ill patients with nosocomial catheter-related bloodstream infections. Clinical Infectious Diseases 41 (2005) 1591-1598
73. Pittet D., Tarara D., and Wenzel R.P. Nosocomial bloodstream infection in critically ill patients. Excess length of stay, extra costs, and attributable mortality. JAMA : The Journal of the American Medical Association 271 (1994) 1598-1601
74. Halton K., and Graves N. Economic evaluation and catheter-related bloodstream infections. Emerging Infectious Diseases 13 (2007) 815-823
75. Das I., Philpott C., and George R.H. Central venous catheter-related septicaemia in paediatric cancer patients. The Journal of Hospital Infection 36 (1997) 67-76
76. Pronovost P., Needham D., Berenholtz S., et al. An intervention to decrease catheter-related bloodstream infections in the ICU. The New England Journal of Medicine 355 (2006) 2725-2732
77. Lindblad B., and Wolff T. Infectious complications of percutaneously inserted central venous catheters. Acta Anaesthesiologica Scandinavica 29 (1985) 587-589
78. Raad I.I., Hohn D.C., Gilbreath B.J., et al. Prevention of central venous catheter-related infections by using maximal sterile barrier precautions during insertion. Infection Control and Hospital Epidemiology 15 (1994) 231-238
79. Berenholtz S.M., Pronovost P.J., Lipsett P.A., et al. Eliminating catheter-related bloodstream infections in the intensive care unit. Critical Care Medicine 32 (2004) 2014-2020
80. Tsuchida T., Makimoto K., Toki M., et al. The effectiveness of a nurse-initiated intervention to reduce catheter-associated bloodstream infections in an urban acute hospital: an intervention study with before and after comparison. International Journal of Nursing Studies 44 (2007) 1324-1333
81. Eggimann P., Harbarth S., Constantin M.N., et al. Impact of a prevention strategy targeted at vascular-access care on incidence of infections acquired in intensive care. Lancet 355 (2000) 1864-1868
82. Falagas M.E., Fragoulis K., Bliziotis I.A., and Chatzinikolaou I. Rifampicin-impregnated central venous catheters: a meta-analysis of randomized controlled trials. The Journal of Antimicrobial Chemotherapy 59 (2007) 359-369
83. Abdelkefi A., Ben Othman T., Kammoun L., et al. Prevention of central venous line-related thrombosis by continuous infusion of low-dose unfractionated heparin, in patients with haemato-oncological disease. A randomized controlled trial. Thrombosis and Haemostasis 92 (2004) 654-661
84. Abdelkefi A., Achour W., Ben Othman T., et al. Use of heparin-coated central venous lines to prevent catheter-related bloodstream infection. The Journal of Supportive Oncology 5 (2007) 273-278
85. van Rooden C.J., Schippers E.F., Guiot H.F., et al. Prevention of coagulase-negative staphylococcal central venous catheter-related infection using urokinase rinses: a randomized double-blind controlled trial in patients with hematologic malignancies. The Journal of Supportive Oncology 26 (2008) 428-433
86. Dillon P.W., Jones G.R., Bagnall-Reeb H.A., et al. Prophylactic urokinase in the management of long-term venous access devices in children: a Children's Oncology Group study. The Journal of Supportive Oncology 22 (2004) 2718-2723
87. Kalmanti M., Germanakis J., Stiakaki E., et al. Prophylaxis with urokinase in pediatric oncology patients with central venous catheters. Pediatric Hematology and Oncology 19 (2002) 173-179
88. Eggimann P., Hugonnet S., Sax H., et al. Long-term reduction of vascular access-associated bloodstream infection. Annals of Internal Medicine 142 (2005) 875-876
89. Valiquette L., Cossette B., Garant M.P., et al. Impact of a reduction in the use of high-risk antibiotics on the course of an epidemic of Clostridium difficile-associated disease caused by the hypervirulent NAP1/027 strain. Clinical Infectious Diseases 45 (2007) S112-S121
90. McKibben L., Horan T., Tokars J.I., et al. Guidance on public reporting of healthcare-associated infections: recommendations of the Healthcare Infection Control Practices Advisory Committee. American Journal of Infection Control 33 (2005) 217-226
91. Trick W.E., Zagorski B.M., Tokars J.I., et al. Computer algorithms to detect bloodstream infections. Emerging Infectious Diseases 10 (2004) 1612-1620
92. Cook D., Randolph A., Kernerman P., et al. Central venous catheter replacement strategies: a systematic review of the literature. Critical Care Medicine 25 (1997) 1417-1424
93. Chen H.S., Wang F.D., Lin M., et al. Risk factors for central venous catheter-related infections in general surgery. Journal of Microbiology, Immunology, and Infection 39 (2006) 231-236
94. Soufir L., Timsit J.F., Mahe C., et al. Attributable morbidity and mortality of catheter-related septicemia in critically ill patients: a matched, risk-adjusted, cohort study. Infection Control and Hospital Epidemiology 20 (1999) 396-401
95. Digiovine B., Chenoweth C., Watts C., and Higgins M. The attributable mortality and costs of primary nosocomial bloodstream infections in the intensive care unit. American journal of Respiratory and Critical Care Medicine 160 (1999) 976-981
96. Rello J., Ochagavia A., Sabanes E., et al. Evaluation of outcome of intravenous catheter-related infections in critically ill patients. American Journal of Respiratory and Critical Care Medicine 162 (2000) 1027-1030
97. Pelletier S.J., Crabtree T.D., Gleason T.G., et al. Bacteremia associated with central venous catheter infection is not an independent predictor of outcomes. Journal of the American College of Surgeons 190 (2000) 671-680
98. Renaud B., and Brun-Buisson C. Outcomes of primary and catheter-related bacteremia. A cohort and case-control study in critically ill patients. American Journal of Respiratory and Critical Care Medicine 163 (2001) 1584-1590
99. Rosenthal V.D., Guzman S., Migone O., et al. The attributable cost, length of hospital stay, and mortality of central line-associated bloodstream infection in intensive care departments in Argentina: A prospective, matched analysis. American Journal of Infection Control 31 (2003) 475-480