Incidence of healthcare-associated infections in high-risk neonates: results from the German surveillance system for very-low-birthweight infants

Journal of Hospital Infection

Volumn 68, Issue 3, 2008, Pages 214-221

  Geffers, C ^a,b   Baerwolff, S ^a,b   Schwab, F ^a,b   Gastmeier, P ^b,c  

^a National Reference Center for Surveillance of Nosocomial Infections   (Germany)

^b CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

^c HANNOVER MEDICAL SCHOOL   (Germany)

Author keywords

Bloodstream infection; Healthcare associated infection; Pneumonia; Surveillance; Very low birthweight

Indexed keywords

ARTICLE; ARTIFICIAL VENTILATION; BACTEREMIA; CALCULATION; CATHETER INFECTION; CENTRAL VENOUS CATHETER; CONTROLLED STUDY; ENDOTRACHEAL INTUBATION; FEMALE; GERMANY; HIGH RISK PATIENT; HOSPITAL INFECTION; HUMAN; INCIDENCE; INFECTION CONTROL; INFECTION RATE; MAJOR CLINICAL STUDY; MALE; NECROTIZING ENTEROCOLITIS; NEONATOLOGY; NEWBORN; NEWBORN INFECTION; NONHUMAN; PNEUMONIA; POSITIVE END EXPIRATORY PRESSURE; VENTILATED PATIENT; VENTILATOR ASSOCIATED PNEUMONIA; VERY LOW BIRTH WEIGHT;

BACTEREMIA; CROSS INFECTION; ENTEROCOLITIS, NECROTIZING; FEMALE; GERMANY; HUMANS; INCIDENCE; INFANT, NEWBORN; INFANT, PREMATURE; INFANT, VERY LOW BIRTH WEIGHT; INTENSIVE CARE UNITS, NEONATAL; MALE; PNEUMONIA; SENTINEL SURVEILLANCE;

EID: 40649102875     PISSN: 01956701     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jhin.2008.01.016     Document Type: Article

References (42)

1. Jarvis W.R. Epidemiology of nosocomial infections in pediatric patients. Pediatr Infect Dis J 6 (1987) 344-351
2. Auriti C., Maccallini A., Di Liso G., Di Ciommo V., Ronchetti M.P., and Orzalesi M. Risk factors for nosocomial infections in a neonatal intensive-care unit. J Hosp Infect 53 (2003) 25-30
3. Drews M.B., Ludwig A.C., Leititis J.U., and Daschner F.D. Low birth weight and nosocomial infection of neonates in a neonatal intensive care unit. J Hosp Infect 30 (1995) 65-72
4. Barton L., Hodgman J.E., and Pavlova Z. Causes of death in the extremely low birth weight infant. Pediatrics 103 (1999) 446-451
5. Stoll B.J., and Hansen N. Infections in VLBW infants: studies from the NICHD Neonatal Research Network. Semin Perinatol 27 (2003) 293-301
6. Zafar N., Wallace C.M., Kieffer P., Schroeder P., Schootman M., and Hamvas A. Improving survival of vulnerable infants increases neonatal intensive care unit nosocomial infection rate. Arch Pediatr Adolesc Med 155 (2001) 1098-1104
7. Townsend T.R., and Wenzel R.P. Nosocomial bloodstream infections in a newborn intensive care unit: a case-matched control study of morbidity, mortality and risk. Am J Epidemiol 114 (1981) 73-80
8. Sohn A.H., Garrett D.O., Sinkowitz-Cochran R.L., et al. Prevalence of nosocomial infections in neonatal intensive care unit patients: results from the first national point-prevalence survey. J Pediatr 139 (2001) 821-827
9. Stoll B.J., Hansen N., Fanaroff A.A., et al. Late-onset sepsis in very low birth weight neonates: the experience of the NICHD Neonatal Research Network. Pediatrics 110 2 Pt 1 (2002) 285-291
10. Leroyer A., Bedu A., Lombrail P., et al. Prolongation of hospital stay and extra costs due to hospital-acquired infection in a neonatal unit. J Hosp Infect 35 (1997) 37-45
11. Mahieu L.M., Buitenweg N., Beutels P., and De Dooy J.J. Additional hospital stay and charges due to hospital-acquired infections in a neonatal intensive care unit. J Hosp Infect 47 (2001) 223-229
12. Stone P.W., Gupta A., Loughrey M., et al. Attributable costs and length of stay of an extended-spectrum beta-lactamase-producing Klebsiella pneumoniae outbreak in a neonatal intensive care unit. Infect Control Hosp Epidemiol 24 (2003) 601-606
13. Hintz S.R., Kendrick D.E., Stoll B.J., et al. Neurodevelopmental and growth outcomes of extremely low birth weight infants after necrotizing enterocolitis. Pediatrics 115 (2005) 696-703
14. Vohr B.R., Wright L.L., Dusick A.M., et al. Neurodevelopmental and functional outcomes of extremely low birth weight infants in the National Institute of Child Health and Human Development Neonatal Research Network, 1993-1994. Pediatrics 105 (2000) 1216-1226
15. Hack M., Wilson-Costello D., Friedman H., Taylor G.H., Schluchter M., and Fanaroff A.A. Neurodevelopment and predictors of outcomes of children with birth weights of less than 1000 g: 1992-1995. Arch Pediatr Adolesc Med 154 (2000) 725-7231
16. Wilson-Costello D., Borawski E., Friedman H., Redline R., Fanaroff A.A., and Hack M. Perinatal correlates of cerebral palsy and other neurologic impairment among very low birth weight children. Pediatrics 102 2 Pt 1 (1998) 315-322
17. Hughes J.M. Study on the efficacy of nosocomial infection control (SENIC Project): results and implications for the future. Chemotherapy 34 (1988) 553-561
18. Schwab F., Geffers C., Barwolff S., Ruden H., and Gastmeier P. Reducing neonatal nosocomial bloodstream infections through participation in a national surveillance system. J Hosp Infect 65 (2007) 319-325
19. Gastmeier P., Brauer H., Forster D., Dietz E., Daschner F., and Ruden H. A quality management project in 8 selected hospitals to reduce nosocomial infections: a prospective, controlled study. Infect Control Hosp Epidemiol 23 (2002) 91-97
20. Zuschneid I., Schwab F., Geffers C., Ruden H., and Gastmeier P. Reducing central venous catheter-associated primary bloodstream infections in intensive care units is possible: data from the German nosocomial infection surveillance system. Infect Control Hosp Epidemiol 24 (2003) 501-505
21. Zuschneid I., Schwab F., Geffers C., Behnke M., Ruden H., and Gastmeier P. Trends in ventilator-associated pneumonia rates within the German nosocomial infection surveillance system (KISS). Infect Control Hosp Epidemiol 28 (2007) 314-318
22. Gaynes R.P., Edwards J.R., Jarvis W.R., Culver D.H., Tolson J.S., and Martone W.J. Nosocomial infections among neonates in high-risk nurseries in the United States. National Nosocomial Infections Surveillance System. Pediatrics 98 3 Pt 1 (1996) 357-361
23. National Nosocomial Infections Surveillance (NNIS) System Report, data summary from January 1992 through June 2004, issued October 2004. Am J Infect Control 32 (2004) 470-485
24. Gastmeier P., Geffers C., Schwab F., Fitzner J., Obladen M., and Ruden H. Development of a surveillance system for nosocomial infections: the component for neonatal intensive care units in Germany. J Hosp Infect 57 (2004) 126-131
25. Hentschel J., de Veer I., Gastmeier P., Ruden H., and Obladen M. Neonatal nosocomial infection surveillance: incidences by site and a cluster of necrotizing enterocolitis. Infection 27 (1999) 234-238
26. Cooke E.M., Coello R., Sedgwick J., et al. A national surveillance scheme for hospital associated infections in England. Team of the Nosocomial Infection National Surveillance Scheme. J Hosp Infect 46 (2000) 1-3
27. Reed C.S., Gorrie G., and Spelman D. Hospital infection control in Australia. J Hosp Infect 54 (2003) 267-271
28. Cook D.J., Walter S.D., Cook R.J., et al. Incidence of and risk factors for ventilator-associated pneumonia in critically ill patients. Ann Intern Med 129 (1998) 433-440
29. Lee S.K., McMillan D.D., Ohlsson A., et al. Variations in practice and outcomes in the Canadian NICU network: 1996-1997. Pediatrics 106 (2000) 1070-1079
30. National Nosocomial Infections Surveillance (NNIS) System Report, data summary from January 1992 through June 2003, issued August 2003. Am J Infect Control 31 (2003) 481-498
31. Gastmeier P., Hentschel J., de Veer I., Obladen M., and Ruden H. Device-associated nosocomial infection surveillance in neonatal intensive care using specified criteria for neonates. J Hosp Infect 38 (1998) 51-60
32. Ekelem I., and Taeusch H.W. Defining quality of care indicators for neonatal intensive care units independent of maternal risk factors. J Natl Med Assoc 82 (1990) 345-350
33. Stover B.H., Shulman S.T., Bratcher D.F., Brady M.T., Levine G.L., and Jarvis W.R. Nosocomial infection rates in US children's hospitals' neonatal and pediatric intensive care units. Am J Infect Control 29 (2001) 152-157
34. Tseng Y.C., Chiu Y.C., Wang J.H., Lin H.C., Su B.H., and Chiu H.H. Nosocomial bloodstream infection in a neonatal intensive care unit of a medical center: a three-year review. J Microbiol Immunol Infect 35 (2002) 168-172
35. Lopez Sastre J.B., Coto Cotallo D., and Fernandez Colomer B. Neonatal sepsis of nosocomial origin: an epidemiological study from the "Grupo de Hospitales Castrillo". J Perinat Med 30 (2002) 149-157
36. Brodie S.B., Sands K.E., Gray J.E., et al. Occurrence of nosocomial bloodstream infections in six neonatal intensive care units. Pediatr Infect Dis J 19 (2000) 56-65
37. Halder D., Haque M.E., Zabidi M.H., and Kamaruzzaman A. Nosocomial bacterial sepsis in babies weighing 1000-1499 g in Kelantan. Med J Malaysia 54 (1999) 52-57
38. Fanaroff A.A., Korones S.B., Wright L.L., et al. Incidence, presenting features, risk factors and significance of late onset septicemia in very low birth weight infants. The National Institute of Child Health and Human Development Neonatal Research Network. Pediatr Infect Dis J 17 (1998) 593-598
39. Beck-Sague C.M., Azimi P., Fonseca S.N., et al. Bloodstream infections in neonatal intensive care unit patients: results of a multicenter study. Pediatr Infect Dis J 13 (1994) 1110-1116
40. Geffers C., Zuschneid I., Sohr D., Ruden H., and Gastmeier P. Microbiological isolates associated with nosocomial infections in intensive care units: data of 274 intensive care units participating in the German Nosocomial Infections Surveillance System (KISS). Anasthesiol Intensivmed Notfallmed Schmerzther 39 (2004) 15-19
41. Anonymous. National Nosocomial Infections Surveillance (NNIS) System report, data summary from January 1990-May 1999, issued June 1999. Am J Infect Control 27 (1999) 520-532
42. Rettwitz-Volk W. Indices of birthweight-specific perinatal mortality in Germany from 1985 to 1999. Paediatr Perinat Epidemiol 16 (2002) 383-385