메뉴 건너뛰기




Volumn 13, Issue 3-4, 2008, Pages 393-402

Lack of effect of chronic dextromethorphan on experimental pain tolerance in methadone-maintained patients

Author keywords

Cold pressor pain; Dextromethorphan; Electrical stimulation pain; Hyperalgesia; Methadone; Opiods

Indexed keywords

DEXTROMETHORPHAN; METHADONE; PLACEBO;

EID: 49349105620     PISSN: 13556215     EISSN: 13691600     Source Type: Journal    
DOI: 10.1111/j.1369-1600.2008.00112.x     Document Type: Article
Times cited : (27)

References (77)
  • 1
    • 33644805884 scopus 로고    scopus 로고
    • Acute pain management for patients receiving maintenance methadone or buprenorphine therapy
    • Alford DP, Compton P, Samet JH (2006) Acute pain management for patients receiving maintenance methadone or buprenorphine therapy. Ann Intern Med 17 : 127 134.
    • (2006) Ann Intern Med , vol.17 , pp. 127-134
    • Alford, D.P.1    Compton, P.2    Samet, J.H.3
  • 2
    • 22544477115 scopus 로고    scopus 로고
    • Ketamine use for reduction of opioid tolerance in a 5-year-old girl with end-stage abdominal neuroblastoma
    • Anghelescu DL, Oakes LL (2005) Ketamine use for reduction of opioid tolerance in a 5-year-old girl with end-stage abdominal neuroblastoma. J Pain Symptom Manage 30 : 1 3.
    • (2005) J Pain Symptom Manage , vol.30 , pp. 1-3
    • Anghelescu, D.L.1    Oakes, L.L.2
  • 3
    • 33645509700 scopus 로고    scopus 로고
    • Opioid-induced hyperalgesia; A qualitative systematic review
    • Angst MS, Clark JD (2006) Opioid-induced hyperalgesia; a qualitative systematic review. Anesthesiology 104 : 570 587.
    • (2006) Anesthesiology , vol.104 , pp. 570-587
    • Angst, M.S.1    Clark, J.D.2
  • 4
    • 0142196082 scopus 로고    scopus 로고
    • Short-term infusion of the mu-opioid agonist remifentanil in humans causes hyperalgesia during withdrawal
    • Angst MS, Koppert W, Pahl I, Clark DJ, Schmelz M (2003) Short-term infusion of the mu-opioid agonist remifentanil in humans causes hyperalgesia during withdrawal. Pain 106 : 49 57.
    • (2003) Pain , vol.106 , pp. 49-57
    • Angst, M.S.1    Koppert, W.2    Pahl, I.3    Clark, D.J.4    Schmelz, M.5
  • 5
    • 31644449011 scopus 로고    scopus 로고
    • Methadone maintenance patients are cross tolerant to the antinociceptive effects of very high plasma morphine concentrations
    • Athanasos P, Smith CS, White JM, Somogyi AA, Bochner F, Ling W (2006) Methadone maintenance patients are cross tolerant to the antinociceptive effects of very high plasma morphine concentrations. Pain 120 : 267 275.
    • (2006) Pain , vol.120 , pp. 267-275
    • Athanasos, P.1    Smith, C.S.2    White, J.M.3    Somogyi, A.A.4    Bochner, F.5    Ling, W.6
  • 6
    • 33745815972 scopus 로고    scopus 로고
    • NMDA-receptor antagonism during the development of morphine analgesic tolerance in male, but not female C57BL/6J mice
    • Bryant CD, Eitan S, Sinchak K, Fanselow MS, Evans CJ (2006) NMDA-receptor antagonism during the development of morphine analgesic tolerance in male, but not female C57BL/6J mice. Am J Physiol Regul Integr Comp Physiol 291 : 315 326.
    • (2006) Am J Physiol Regul Integr Comp Physiol , vol.291 , pp. 315-326
    • Bryant, C.D.1    Eitan, S.2    Sinchak, K.3    Fanselow, M.S.4    Evans, C.J.5
  • 7
    • 11144261003 scopus 로고    scopus 로고
    • Ethnic differences in response to multiple experimental pain stimuli
    • Campbell CM, Edwards RR, Filligim RB (2005) Ethnic differences in response to multiple experimental pain stimuli. Pain 205 : 20 26.
    • (2005) Pain , vol.205 , pp. 20-26
    • Campbell, C.M.1    Edwards, R.R.2    Filligim, R.B.3
  • 8
    • 0345035480 scopus 로고    scopus 로고
    • Evidence for opiate-activated NMDA processes masking opiate analgesia in rats
    • Celerier E, Laulin J, Larcher A, Le Moal M, Simonnet G (1999) Evidence for opiate-activated NMDA processes masking opiate analgesia in rats. Brain Res 847 : 18 25.
    • (1999) Brain Res , vol.847 , pp. 18-25
    • Celerier, E.1    Laulin, J.2    Larcher, A.3    Le Moal, M.4    Simonnet, G.5
  • 11
    • 33847178772 scopus 로고    scopus 로고
    • Opioid tolerance and hyperalgesia
    • Chang G, Chen L, Mao J (2007) Opioid tolerance and hyperalgesia. Med Clin North Am 91 : 199 211.
    • (2007) Med Clin North Am , vol.91 , pp. 199-211
    • Chang, G.1    Chen, L.2    Mao, J.3
  • 12
    • 0030933616 scopus 로고    scopus 로고
    • Efficacy of spinal NMDA receptor antagonism in formalin hyperalgesia and nerve injury evoked allodynia in the rat
    • Chaplan SR, Malmberg AB, Yaksh TL (1997) Efficacy of spinal NMDA receptor antagonism in formalin hyperalgesia and nerve injury evoked allodynia in the rat. J Pharmacol Exp Ther 280 : 829 838.
    • (1997) J Pharmacol Exp Ther , vol.280 , pp. 829-838
    • Chaplan, S.R.1    Malmberg, A.B.2    Yaksh, T.L.3
  • 13
    • 30744442773 scopus 로고    scopus 로고
    • Opioid tolerance and hyperalgesia in chronic pain patients after one month of oral morphine therapy: A preliminary prospective study
    • Chu LF, Clark DJ, Angst MS (2006) Opioid tolerance and hyperalgesia in chronic pain patients after one month of oral morphine therapy: a preliminary prospective study. J Pain 7 : 43 48.
    • (2006) J Pain , vol.7 , pp. 43-48
    • Chu, L.F.1    Clark, D.J.2    Angst, M.S.3
  • 14
    • 0029833205 scopus 로고    scopus 로고
    • System theory of pain and of opiate analgesia: No tolerance to opiates
    • Colpaert FC (1996) System theory of pain and of opiate analgesia: no tolerance to opiates. Pharmacol Rev 48 : 355 408.
    • (1996) Pharmacol Rev , vol.48 , pp. 355-408
    • Colpaert, F.C.1
  • 17
    • 1642579573 scopus 로고    scopus 로고
    • Neuroimmune activation and neuroinflammation in chronic pain and opioid tolerance/hyperalgesia
    • DeLeo JA, Tanga FY, Tawfik VL (2004) Neuroimmune activation and neuroinflammation in chronic pain and opioid tolerance/hyperalgesia. Neuroscientist 10 : 40 52.
    • (2004) Neuroscientist , vol.10 , pp. 40-52
    • Deleo, J.A.1    Tanga, F.Y.2    Tawfik, V.L.3
  • 18
    • 0028973267 scopus 로고
    • Simultaneous activation of spinal antiopioid system (neuropeptide FF) and pain facilitatory circuitry by stimulation of opioid receptors in rats
    • Devillers JP, Boisserie F, Laulin JP, Larcher A, Simonnet G (1995) Simultaneous activation of spinal antiopioid system (neuropeptide FF) and pain facilitatory circuitry by stimulation of opioid receptors in rats. Brain Res 700 : 173 181.
    • (1995) Brain Res , vol.700 , pp. 173-181
    • Devillers, J.P.1    Boisserie, F.2    Laulin, J.P.3    Larcher, A.4    Simonnet, G.5
  • 20
    • 28344441968 scopus 로고    scopus 로고
    • Spinal L-type calcium channel blockade abolishes opioid-induced sensory hypersensitivity and antinociceptive tolerance
    • Drogul A, Bilsky EJ, Ossipov MH, Lai J, Porreca F (2005) Spinal L-type calcium channel blockade abolishes opioid-induced sensory hypersensitivity and antinociceptive tolerance. Anesth Analg 101 : 1730 1735.
    • (2005) Anesth Analg , vol.101 , pp. 1730-1735
    • Drogul, A.1    Bilsky, E.J.2    Ossipov, M.H.3    Lai, J.4    Porreca, F.5
  • 21
    • 33947728305 scopus 로고    scopus 로고
    • A phase III randomized, double-blind, placebo-controlled study evaluating dextromethorphan plus slow-release morphine for chronic cancer pain relief in terminally ill patients
    • Dudgeon DJ, Bruera E, Gagnon B, Watanabe SM, Allan SJ, Warr DG, MacDonald SM, Savage C, Tu D, Pater JL (2007) A phase III randomized, double-blind, placebo-controlled study evaluating dextromethorphan plus slow-release morphine for chronic cancer pain relief in terminally ill patients. J Pain Symptom Manage 33 : 365 371.
    • (2007) J Pain Symptom Manage , vol.33 , pp. 365-371
    • Dudgeon, D.J.1    Bruera, E.2    Gagnon, B.3    Watanabe, S.M.4    Allan, S.J.5    Warr, D.G.6    MacDonald, S.M.7    Savage, C.8    Tu, D.9    Pater, J.L.10
  • 22
    • 0036045948 scopus 로고    scopus 로고
    • Analgesia with ketamine in a patient with perioperative opioid tolerance
    • Duncan MA, Spiller JA (2002) Analgesia with ketamine in a patient with perioperative opioid tolerance. J Pain Symptom Manage 24 : 8 11.
    • (2002) J Pain Symptom Manage , vol.24 , pp. 8-11
    • Duncan, M.A.1    Spiller, J.A.2
  • 23
    • 0033017188 scopus 로고    scopus 로고
    • Steady-state pharmacokinetics and pharmacodynamics in methadone maintenance patients: Comparison of those who do and do not experience withdrawal and concentration-effect relationships
    • Dyer KR, Foster DJ, White JM, Somogyi AA, Menelaou A, Bochner F (1999) Steady-state pharmacokinetics and pharmacodynamics in methadone maintenance patients: comparison of those who do and do not experience withdrawal and concentration-effect relationships. Clin Pharmacol Ther 65 : 685 694.
    • (1999) Clin Pharmacol Ther , vol.65 , pp. 685-694
    • Dyer, K.R.1    Foster, D.J.2    White, J.M.3    Somogyi, A.A.4    Menelaou, A.5    Bochner, F.6
  • 24
    • 0031746749 scopus 로고    scopus 로고
    • Same incidence of adverse drug events after codeine administration irrespective of the genetically determined differences in morphine formation
    • Eckhardt K, Li S, Ammon S, Schanzle G, Mikus G, Eichelbaum M (1998) Same incidence of adverse drug events after codeine administration irrespective of the genetically determined differences in morphine formation. Pain 76 : 27 33.
    • (1998) Pain , vol.76 , pp. 27-33
    • Eckhardt, K.1    Li, S.2    Ammon, S.3    Schanzle, G.4    Mikus, G.5    Eichelbaum, M.6
  • 25
    • 0035091466 scopus 로고    scopus 로고
    • Ethnic differences in pain tolerance: Clinical implications in a chronic pain population
    • Edwards RR, Doleys DM, Fillingim RB, Lowery D (2001) Ethnic differences in pain tolerance: Clinical implications in a chronic pain population. Psychosom Med 63 : 316 323.
    • (2001) Psychosom Med , vol.63 , pp. 316-323
    • Edwards, R.R.1    Doleys, D.M.2    Fillingim, R.B.3    Lowery, D.4
  • 26
    • 0032967568 scopus 로고    scopus 로고
    • Ethnic differences in thermal pain responses
    • Edwards RR, Fillingim RB (1999) Ethnic differences in thermal pain responses. Psychosom Med 61 : 346 354.
    • (1999) Psychosom Med , vol.61 , pp. 346-354
    • Edwards, R.R.1    Fillingim, R.B.2
  • 28
    • 19444383083 scopus 로고    scopus 로고
    • MorphiDex (morphine sulfate/dextromethorphan hydrobromide combination) in the treatment of chronic pain: Three multicenter, randomized, double-blind, controlled clinical trials fail to demonstrate enhanced opioid analgesia or reduction in tolerance
    • Galer BS, Lee D, Ma T, Nagle B, Schlagheck TG (2005) MorphiDex (morphine sulfate/dextromethorphan hydrobromide combination) in the treatment of chronic pain: three multicenter, randomized, double-blind, controlled clinical trials fail to demonstrate enhanced opioid analgesia or reduction in tolerance. Pain 115 : 284 295.
    • (2005) Pain , vol.115 , pp. 284-295
    • Galer, B.S.1    Lee, D.2    Ma, T.3    Nagle, B.4    Schlagheck, T.G.5
  • 29
    • 32544435149 scopus 로고    scopus 로고
    • Opioid receptor-mediated hyperalgesia and antinociceptive tolerance induced by sustained opiate delivery
    • Gardell LR, King T, Ossipov MH, Rice KC, Lai J, Vanderah TW, Porreca F (2006) Opioid receptor-mediated hyperalgesia and antinociceptive tolerance induced by sustained opiate delivery. Neurosci Lett 396 : 44 49.
    • (2006) Neurosci Lett , vol.396 , pp. 44-49
    • Gardell, L.R.1    King, T.2    Ossipov, M.H.3    Rice, K.C.4    Lai, J.5    Vanderah, T.W.6    Porreca, F.7
  • 30
    • 0036703883 scopus 로고    scopus 로고
    • Sustained morphine exposure induces a spinal dynorphin-dependent enhancement of excitatory transmitter release from primary afferent fibers
    • Gardell LR, Wang R, Burgess SE, Ossipov MH, Vanderah TW, Malan Jr. TP, Lai J, Porreca F (2002) Sustained morphine exposure induces a spinal dynorphin-dependent enhancement of excitatory transmitter release from primary afferent fibers. J Neurosci 22 : 6747 6755.
    • (2002) J Neurosci , vol.22 , pp. 6747-6755
    • Gardell, L.R.1    Wang, R.2    Burgess, S.E.3    Ossipov, M.H.4    Vanderah, T.W.5    Tp, M.J.6    Lai, J.7    Porreca, F.8
  • 31
    • 0036213896 scopus 로고    scopus 로고
    • Analgesic effects of dextromethorphan and morphine in patients with chronic pain
    • Heiskanen T, Hartel B, Dahl ML, Seppala T, Kalso E (2002) Analgesic effects of dextromethorphan and morphine in patients with chronic pain. Pain 96 : 261 267.
    • (2002) Pain , vol.96 , pp. 261-267
    • Heiskanen, T.1    Hartel, B.2    Dahl, M.L.3    Seppala, T.4    Kalso, E.5
  • 32
    • 0035123716 scopus 로고    scopus 로고
    • The effect of the preemptive use of the NMDA receptor antagonist dextromethorphan on postoperative analgesic requirements
    • Helmy SA, Bali A (2001) The effect of the preemptive use of the NMDA receptor antagonist dextromethorphan on postoperative analgesic requirements. Anesth Analg 92 : 739 744.
    • (2001) Anesth Analg , vol.92 , pp. 739-744
    • Helmy, S.A.1    Bali, A.2
  • 33
    • 14044278005 scopus 로고    scopus 로고
    • Characterization of morphine-induced hyperalgesia in male and female rats
    • Holtman JR, Wala EP (2005) Characterization of morphine-induced hyperalgesia in male and female rats. Pain 114 : 62 70.
    • (2005) Pain , vol.114 , pp. 62-70
    • Holtman, J.R.1    Wala, E.P.2
  • 35
    • 4944220173 scopus 로고    scopus 로고
    • Inhibition of morphine analgesia by LPS: Role of opioid and NMDA receptors and spinal glia
    • Johnston IN, Westbrook RF (2005) Inhibition of morphine analgesia by LPS: role of opioid and NMDA receptors and spinal glia. Behav Brain Res 156 : 75 83.
    • (2005) Behav Brain Res , vol.156 , pp. 75-83
    • Johnston, I.N.1    Westbrook, R.F.2
  • 36
    • 0033858570 scopus 로고    scopus 로고
    • Gender differences in opioid-mediated analgesia: Animal and human studies
    • Kest B, Sarton E, Dahan A (2000) Gender differences in opioid-mediated analgesia: animal and human studies. Anesthesiology 93 : 539 547.
    • (2000) Anesthesiology , vol.93 , pp. 539-547
    • Kest, B.1    Sarton, E.2    Dahan, A.3
  • 37
    • 6944221102 scopus 로고    scopus 로고
    • Comparison of experimental and acute clinical pain responses in humans as pain phenotypes
    • Kim H, Neubert JK, Rowan JS, Brahim JS, Iadarola MJ, Dionne RA (2004) Comparison of experimental and acute clinical pain responses in humans as pain phenotypes. J Pain 5 : 377 384.
    • (2004) J Pain , vol.5 , pp. 377-384
    • Kim, H.1    Neubert, J.K.2    Rowan, J.S.3    Brahim, J.S.4    Iadarola, M.J.5    Dionne, R.A.6
  • 39
    • 26244461682 scopus 로고    scopus 로고
    • Is paradoxical pain induced by sustained opioid exposure an underlying mechanism of opioid antinociceptive tolerance?
    • King T, Ossipov MH, Vanderah TW, Porreca F, Lai J (2005b) Is paradoxical pain induced by sustained opioid exposure an underlying mechanism of opioid antinociceptive tolerance? Neurosignals 14 : 194 205.
    • (2005) Neurosignals , vol.14 , pp. 194-205
    • King, T.1    Ossipov, M.H.2    Vanderah, T.W.3    Porreca, F.4    Lai, J.5
  • 40
    • 33947602618 scopus 로고    scopus 로고
    • The impact of opioid-induced hyperalgesia for postoperative pain
    • Koppert W, Schmelz M (2007) The impact of opioid-induced hyperalgesia for postoperative pain. Best Pract Res Clin Anaesthesiol 21 : 65 83.
    • (2007) Best Pract Res Clin Anaesthesiol , vol.21 , pp. 65-83
    • Koppert, W.1    Schmelz, M.2
  • 41
    • 0038787535 scopus 로고    scopus 로고
    • Differential modulation of remifentanil-induced analgesia and postinfusion hyperalgesia by S-ketamine and clonidine in humans
    • Koppert W, Sittl R, Scheuber K, Alsheimer M, Schmelz M, Schuttler J (2003) Differential modulation of remifentanil-induced analgesia and postinfusion hyperalgesia by S-ketamine and clonidine in humans. Anesthesiology 99 : 152 159.
    • (2003) Anesthesiology , vol.99 , pp. 152-159
    • Koppert, W.1    Sittl, R.2    Scheuber, K.3    Alsheimer, M.4    Schmelz, M.5    Schuttler, J.6
  • 42
    • 0031937382 scopus 로고    scopus 로고
    • Acute tolerance associated with a single opiate administration: Involvement of N-methyl-D-aspartate-dependent pain facilitatory systems
    • Larcher A, Laulin JP, Celerier E, Le Moal M, Simonnet G (1998) Acute tolerance associated with a single opiate administration: Involvement of N-methyl-D-aspartate-dependent pain facilitatory systems. Neuroscience 84 : 583 589.
    • (1998) Neuroscience , vol.84 , pp. 583-589
    • Larcher, A.1    Laulin, J.P.2    Celerier, E.3    Le Moal, M.4    Simonnet, G.5
  • 43
    • 0344097399 scopus 로고    scopus 로고
    • Letters to neuroscience: Opiate tolerance to daily heroin administration: An apparent phenomenon associated with enhanced pain sensitivity
    • Laulin JP, Celerier E, Larcher A, Le Moal M, Simmonet G (1999) Letters to neuroscience: opiate tolerance to daily heroin administration: an apparent phenomenon associated with enhanced pain sensitivity. Neuroscience 89 : 631 636.
    • (1999) Neuroscience , vol.89 , pp. 631-636
    • Laulin, J.P.1    Celerier, E.2    Larcher, A.3    Le Moal, M.4    Simmonet, G.5
  • 44
    • 0036232961 scopus 로고    scopus 로고
    • The role of ketamine in preventing fentanyl-induced hyperalgesia and subsequent acute morphine tolerance
    • Laulin JP, Maurette P, Corcuff JB, Rivat C, Chauvin M, Simonnet G (2002) The role of ketamine in preventing fentanyl-induced hyperalgesia and subsequent acute morphine tolerance. Anesth Analg 94 : 1263 1269.
    • (2002) Anesth Analg , vol.94 , pp. 1263-1269
    • Laulin, J.P.1    Maurette, P.2    Corcuff, J.B.3    Rivat, C.4    Chauvin, M.5    Simonnet, G.6
  • 46
    • 0036898884 scopus 로고    scopus 로고
    • Opioid-induced abnormal pain sensitivity: Implications in clinical opioid therapy
    • Mao J (2002) Opioid-induced abnormal pain sensitivity: implications in clinical opioid therapy. Pain 100 : 213 217.
    • (2002) Pain , vol.100 , pp. 213-217
    • Mao, J.1
  • 47
    • 33645089429 scopus 로고    scopus 로고
    • Opioid-induced abnormal pain sensitivity
    • Mao J (2006) Opioid-induced abnormal pain sensitivity. Curr Pain Headache Rep 10 : 67 70.
    • (2006) Curr Pain Headache Rep , vol.10 , pp. 67-70
    • Mao, J.1
  • 48
    • 0029077507 scopus 로고
    • Experimental mononeuropathy reduces the antinociceptive effects of morphine: Implications for common intracellular mechanisms involved in morphine tolerance and neuropathic pain
    • Mao J, Price D, Mayer D (1995) Experimental mononeuropathy reduces the antinociceptive effects of morphine: implications for common intracellular mechanisms involved in morphine tolerance and neuropathic pain. Pain 61 : 353 364.
    • (1995) Pain , vol.61 , pp. 353-364
    • Mao, J.1    Price, D.2    Mayer, D.3
  • 49
    • 0037107189 scopus 로고    scopus 로고
    • Chronic morphine induces downregulation of spinal glutamate transporters; Implications in morphine tolerance and abnormal pain sensitivity
    • Mao J, Sung B, Lim G (2002) Chronic morphine induces downregulation of spinal glutamate transporters; implications in morphine tolerance and abnormal pain sensitivity. J Neurosci 22 : 8312 8323.
    • (2002) J Neurosci , vol.22 , pp. 8312-8323
    • Mao, J.1    Sung, B.2    Lim, G.3
  • 50
    • 0033529232 scopus 로고    scopus 로고
    • Cellular mechanisms of neuropathic pain, morphine tolerance, and their interactions
    • Mayer DJ, Mao J, Holt J, Price DD (1999) Cellular mechanisms of neuropathic pain, morphine tolerance, and their interactions. Proc Natl Acad Sci USA 96 : 7731 7736.
    • (1999) Proc Natl Acad Sci USA , vol.96 , pp. 7731-7736
    • Mayer, D.J.1    Mao, J.2    Holt, J.3    Price, D.D.4
  • 51
    • 33645639223 scopus 로고    scopus 로고
    • African Americans show alterations in endogenous pain regulatory mechanisms and reduced pain tolerance to experimental pain procedures
    • Mechlin MB, Maixner W, Light KC, Fisher JM, Girdler SS (2005) African Americans show alterations in endogenous pain regulatory mechanisms and reduced pain tolerance to experimental pain procedures. Psychosom Med 67 : 948 956.
    • (2005) Psychosom Med , vol.67 , pp. 948-956
    • Mechlin, M.B.1    Maixner, W.2    Light, K.C.3    Fisher, J.M.4    Girdler, S.S.5
  • 53
    • 0037385039 scopus 로고    scopus 로고
    • Burst ketamine to reverse opioid tolerance in cancer pain
    • Mercadante S, Villari P, Ferrera P (2003b) Burst ketamine to reverse opioid tolerance in cancer pain. J Pain Symptom Manage 25 : 302 305.
    • (2003) J Pain Symptom Manage , vol.25 , pp. 302-305
    • Mercadante, S.1    Villari, P.2    Ferrera, P.3
  • 54
    • 0031021536 scopus 로고    scopus 로고
    • Sex and genotype determine the selective activation of neurochemically-distinct mechanisms of swim stress-induced analgesia
    • Mogil JS, Belknap JK (1997) Sex and genotype determine the selective activation of neurochemically-distinct mechanisms of swim stress-induced analgesia. Pharmacol Biochem Behav 56 : 61 66.
    • (1997) Pharmacol Biochem Behav , vol.56 , pp. 61-66
    • Mogil, J.S.1    Belknap, J.K.2
  • 55
    • 0034152658 scopus 로고    scopus 로고
    • Pain management in the addicted patient: Practical considerations
    • Newshan G (2000) Pain management in the addicted patient: practical considerations. Nurs Outlook 48 : 81 85.
    • (2000) Nurs Outlook , vol.48 , pp. 81-85
    • Newshan, G.1
  • 57
    • 20344362179 scopus 로고    scopus 로고
    • Underlying mechanisms of pronociceptive consequences of prolonged morphine exposure
    • Ossipov MH, Lai J, King T, Vanderah TW, Porreca F (2005) Underlying mechanisms of pronociceptive consequences of prolonged morphine exposure. Biopolymers 80 : 319 324.
    • (2005) Biopolymers , vol.80 , pp. 319-324
    • Ossipov, M.H.1    Lai, J.2    King, T.3    Vanderah, T.W.4    Porreca, F.5
  • 58
    • 33645789099 scopus 로고    scopus 로고
    • Opioids and abnormal pain perception: New evidence from a study of chronic opioid addicts and healthy subjects
    • Pud D, Cohen D, Lawental E, Eisenberg E (2006) Opioids and abnormal pain perception: new evidence from a study of chronic opioid addicts and healthy subjects. Drug Alcohol Depend 82 : 218 223.
    • (2006) Drug Alcohol Depend , vol.82 , pp. 218-223
    • Pud, D.1    Cohen, D.2    Lawental, E.3    Eisenberg, E.4
  • 59
    • 0037112041 scopus 로고    scopus 로고
    • The role of spinal neuroimmune activation in morphine tolerance/hyperalgesia in neuropathic and sham-operated rats
    • Raghavendra V, Rutkowski MD, DeLeo JA (2002) The role of spinal neuroimmune activation in morphine tolerance/hyperalgesia in neuropathic and sham-operated rats. J Neurosci 22 : 9980 9989.
    • (2002) J Neurosci , vol.22 , pp. 9980-9989
    • Raghavendra, V.1    Rutkowski, M.D.2    Deleo, J.A.3
  • 63
    • 27644515470 scopus 로고    scopus 로고
    • Opioids: From analgesia to anti-hyperalgesia?
    • Simonnet G (2005) Opioids: from analgesia to anti-hyperalgesia? Pain 118 : 8 9.
    • (2005) Pain , vol.118 , pp. 8-9
    • Simonnet, G.1
  • 64
    • 0032729936 scopus 로고    scopus 로고
    • Efficacy of pharmacological treatments of neuropathic pain: An update and effect related to mechanism of drug action
    • Sindrup SH, Jensen TS (1999) Efficacy of pharmacological treatments of neuropathic pain: an update and effect related to mechanism of drug action. Pain 83 : 389 400.
    • (1999) Pain , vol.83 , pp. 389-400
    • Sindrup, S.H.1    Jensen, T.S.2
  • 65
    • 0034633666 scopus 로고    scopus 로고
    • Pharmacologic treatment of pain in polyneuropathy
    • Sindrup SH, Jensen TS (2000) Pharmacologic treatment of pain in polyneuropathy. Neurology 55 : 915 920.
    • (2000) Neurology , vol.55 , pp. 915-920
    • Sindrup, S.H.1    Jensen, T.S.2
  • 66
    • 0035111016 scopus 로고    scopus 로고
    • The involvement of glial cells in the development of morphine tolerance
    • Song P, Zhao ZQ (2001) The involvement of glial cells in the development of morphine tolerance. Neurosci Res 39 : 281 286.
    • (2001) Neurosci Res , vol.39 , pp. 281-286
    • Song, P.1    Zhao, Z.Q.2
  • 67
    • 0032149248 scopus 로고    scopus 로고
    • Gender differences in pain sensitivity and responses to analgesia
    • Sun LS (1998) Gender differences in pain sensitivity and responses to analgesia. J Gend Specif Med 1 : 28 30.
    • (1998) J Gend Specif Med , vol.1 , pp. 28-30
    • Sun, L.S.1
  • 68
    • 33746809553 scopus 로고    scopus 로고
    • Amitriptyline suppresses neuroinflammation and upregulates glutamate transporters in morphine-tolerant rats
    • Tai YH, Wang YH, Wang JJ, Tao PL, Tung CS, Wong CS (2006) Amitriptyline suppresses neuroinflammation and upregulates glutamate transporters in morphine-tolerant rats. Pain 124 : 77 86.
    • (2006) Pain , vol.124 , pp. 77-86
    • Tai, Y.H.1    Wang, Y.H.2    Wang, J.J.3    Tao, P.L.4    Tung, C.S.5    Wong, C.S.6
  • 69
    • 28344435216 scopus 로고    scopus 로고
    • A single dose of intrathecal morphine in rats induces long-lasting hyperalgesia: The protective effect of prior administration of ketamine
    • Van Elstraete AC, Sitbon P, Trabold F, Mazoit JX, Benhamou D (2005) A single dose of intrathecal morphine in rats induces long-lasting hyperalgesia: the protective effect of prior administration of ketamine. Anesth Analg 101 : 1750 1756.
    • (2005) Anesth Analg , vol.101 , pp. 1750-1756
    • Van Elstraete, A.C.1    Sitbon, P.2    Trabold, F.3    Mazoit, J.X.4    Benhamou, D.5
  • 71
    • 0035063380 scopus 로고    scopus 로고
    • Mechanisms of opioid-induced pain and antinociceptive tolerance: Descending facilitation and spinal dynorphin
    • Vanderah TW, Ossipov MH, Lai J, Malan TP Jr., Porreca F (2001a) Mechanisms of opioid-induced pain and antinociceptive tolerance: descending facilitation and spinal dynorphin. Pain 92 : 5 9.
    • (2001) Pain , vol.92 , pp. 5-9
    • Vanderah, T.W.1    Ossipov, M.H.2    Lai, J.3    Malan Jr., T.P.4    Porreca, F.5
  • 72
    • 0035141560 scopus 로고    scopus 로고
    • Tonic descending facilitation from the rostral ventromedial medulla mediates opioid-induced abnormal pain and antinociceptive tolerance
    • Vanderah TW, Suengaga NM, Ossipov MH, Malan TP, Lai J, Porreca F (2001b) Tonic descending facilitation from the rostral ventromedial medulla mediates opioid-induced abnormal pain and antinociceptive tolerance. J Neurosci 21 : 279 286.
    • (2001) J Neurosci , vol.21 , pp. 279-286
    • Vanderah, T.W.1    Suengaga, N.M.2    Ossipov, M.H.3    Malan, T.P.4    Lai, J.5    Porreca, F.6
  • 73
    • 9644255673 scopus 로고    scopus 로고
    • Strain and sex differences in the expression of nociceptive behavior and stress-induced analgesia in rats
    • Vendruscolo LF, Pamplona FA, Takahashi RN (2004) Strain and sex differences in the expression of nociceptive behavior and stress-induced analgesia in rats. Brain Res 1030 : 277 283.
    • (2004) Brain Res , vol.1030 , pp. 277-283
    • Vendruscolo, L.F.1    Pamplona, F.A.2    Takahashi, R.N.3
  • 74
    • 0033656015 scopus 로고    scopus 로고
    • The pain of being sick: Implications of immune-to-brain communication for understanding pain
    • Watkins LR, Maier SF (2000) The pain of being sick: implications of immune-to-brain communication for understanding pain. Annu Rev Psychol 51 : 29 57.
    • (2000) Annu Rev Psychol , vol.51 , pp. 29-57
    • Watkins, L.R.1    Maier, S.F.2
  • 75
    • 0035099163 scopus 로고    scopus 로고
    • Dextromethorphan attenuation of postoperative pain and primary and secondary thermal hyperalgesia
    • Weinbroum AA, Gorodezky A, Niv D, Ben-Abraham R, Rudick V, Szold A (2001) Dextromethorphan attenuation of postoperative pain and primary and secondary thermal hyperalgesia. Can J Anaesth 48 : 167 174.
    • (2001) Can J Anaesth , vol.48 , pp. 167-174
    • Weinbroum, A.A.1    Gorodezky, A.2    Niv, D.3    Ben-Abraham, R.4    Rudick, V.5    Szold, A.6
  • 76
    • 33645499127 scopus 로고    scopus 로고
    • Postoperative hyperalgesia: Its clinical importance and relevance
    • Wilder-Smith OH, Arendt-Nielsen L (2006) Postoperative hyperalgesia: its clinical importance and relevance. Anesthesiology 104 : 601 607.
    • (2006) Anesthesiology , vol.104 , pp. 601-607
    • Wilder-Smith, O.H.1    Arendt-Nielsen, L.2
  • 77


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.