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Volumn 1, Issue 2, 2008, Pages 261-276

Idiosyncratic drug hepatotoxicity: A 2008 update

Author keywords

Causality assessment; Chronic DILI; Determinant of prognosis; Drug induced liver injury

Indexed keywords

ACETYLCYSTEINE; AMOXICILLIN; AMOXICILLIN PLUS CLAVULANIC ACID; ANTIBIOTIC AGENT; ANTICONVULSIVE AGENT; ASPARTATE AMINOTRANSFERASE; AZATHIOPRINE; BETAHISTINE; CARBAMAZEPINE; CARNITINE; CEFALEXIN; CHLORPROMAZINE; CORTICOSTEROID; COTRIMOXAZOLE; DICLOFENAC; ERYTHROMYCIN; FLUCLOXACILLIN; ISONIAZID; METOCLOPRAMIDE; NONSTEROID ANTIINFLAMMATORY AGENT; OXYTETRACYCLINE; PARACETAMOL; PLACEBO; SALAZOSULFAPYRIDINE; STOMACH SECRETION INHIBITOR; TICLOPIDINE; TRIMETHOPRIM; UNINDEXED DRUG; URSODEOXYCHOLIC ACID; VITAMIN;

EID: 49249109082     PISSN: 17512433     EISSN: None     Source Type: Journal    
DOI: 10.1586/17512433.1.2.261     Document Type: Review
Times cited : (20)

References (112)
  • 2
    • 0033582161 scopus 로고    scopus 로고
    • Severe hepatotoxicity associated with troglitazone
    • Herrine SK, Choudary C. Severe hepatotoxicity associated with troglitazone. Ann. Intern. Med. 130, 163-164 (1999).
    • (1999) Ann. Intern. Med , vol.130 , pp. 163-164
    • Herrine, S.K.1    Choudary, C.2
  • 4
    • 17444396697 scopus 로고    scopus 로고
    • Hepatic findings in long-term clinical trials of ximelagatran
    • Lee WM, Larrey D, Olsson R et al. Hepatic findings in long-term clinical trials of ximelagatran. Drug Saf. 28, 351-370 (2005).
    • (2005) Drug Saf , vol.28 , pp. 351-370
    • Lee, W.M.1    Larrey, D.2    Olsson, R.3
  • 7
    • 0037973477 scopus 로고    scopus 로고
    • Hepatitis induced by kava (Piper methysticum rhizoma)
    • Stickël F, Baumuller HM, Seitz KH et al. Hepatitis induced by kava (Piper methysticum rhizoma). J. Hepatol. 9, 62-67 (2003).
    • (2003) J. Hepatol , vol.9 , pp. 62-67
    • Stickël, F.1    Baumuller, H.M.2    Seitz, K.H.3
  • 8
    • 1642535488 scopus 로고    scopus 로고
    • Hepatic injury in 12 patients taking the herbal weight loss aids Chaso or onshido
    • Adachi M, Saito H, Kobayashi H et al. Hepatic injury in 12 patients taking the herbal weight loss aids Chaso or onshido. Ann. Intern. Med. 139, 488-492 (2003).
    • (2003) Ann. Intern. Med , vol.139 , pp. 488-492
    • Adachi, M.1    Saito, H.2    Kobayashi, H.3
  • 9
    • 9644272493 scopus 로고    scopus 로고
    • Severe hepatotoxicity associated with the use of weight loss diet supplements containing ma huang or usnic acid
    • Neff GW, Reddy KR, Durazo FA, Meyer D, Marrero R, Kaplowitz N. Severe hepatotoxicity associated with the use of weight loss diet supplements containing ma huang or usnic acid. J. Hepatol. 41, 1062-1064 (2004).
    • (2004) J. Hepatol , vol.41 , pp. 1062-1064
    • Neff, G.W.1    Reddy, K.R.2    Durazo, F.A.3    Meyer, D.4    Marrero, R.5    Kaplowitz, N.6
  • 10
    • 33644776667 scopus 로고    scopus 로고
    • Hepatotoxicity associated with supplements containing Chinese green tea (Camellia sinensis)
    • Bonkovsky HL. Hepatotoxicity associated with supplements containing Chinese green tea (Camellia sinensis). Ann. Intern. Med. 144, 68-71 (2006).
    • (2006) Ann. Intern. Med , vol.144 , pp. 68-71
    • Bonkovsky, H.L.1
  • 11
    • 34548286038 scopus 로고    scopus 로고
    • Herbal does not mean innocuous: 10 cases of severe hepatotoxicity associated with dietary supplements from Herbalife® products
    • Schoepfer AM, Engel A, Fattinger K et al. Herbal does not mean innocuous: 10 cases of severe hepatotoxicity associated with dietary supplements from Herbalife® products. J. Hepatol. 47, 521-526 (2007).
    • (2007) J. Hepatol , vol.47 , pp. 521-526
    • Schoepfer, A.M.1    Engel, A.2    Fattinger, K.3
  • 12
    • 34548212844 scopus 로고    scopus 로고
    • Association between consumption of Herbalife® nutritional supplements and acute hepatotoxicity
    • Elinav E, Pinsker G, Safadi R et al. Association between consumption of Herbalife® nutritional supplements and acute hepatotoxicity. J. Hepatol. 47, 514-520 (2007).
    • (2007) J. Hepatol , vol.47 , pp. 514-520
    • Elinav, E.1    Pinsker, G.2    Safadi, R.3
  • 13
    • 0037126649 scopus 로고    scopus 로고
    • Results of a prospective study of acute liver failure at 17 tertiary care centers in the United States
    • Ostapowicz G, Fontana RJ, Schiødt FV et al. Results of a prospective study of acute liver failure at 17 tertiary care centers in the United States. Ann. Intern. Med. 137, 947-954 (2002).
    • (2002) Ann. Intern. Med , vol.137 , pp. 947-954
    • Ostapowicz, G.1    Fontana, R.J.2    Schiødt, F.V.3
  • 14
    • 19544369808 scopus 로고    scopus 로고
    • Drug-induced liver injury network (DILIN)
    • Hoofnagle JH. Drug-induced liver injury network (DILIN). Hepatology 40, 773 (2004).
    • (2004) Hepatology , vol.40 , pp. 773
    • Hoofnagle, J.H.1
  • 15
    • 18744376412 scopus 로고    scopus 로고
    • Drug- induced liver injury: An analysis of 461 incidences submitted to the Spanish Registry over a 10-year period
    • Andrade RJ, Lucena MI, Fernández MC et al. Drug- induced liver injury: an analysis of 461 incidences submitted to the Spanish Registry over a 10-year period. Gastroenterology 129, 512-521 (2005).
    • (2005) Gastroenterology , vol.129 , pp. 512-521
    • Andrade, R.J.1    Lucena, M.I.2    Fernández, M.C.3
  • 16
    • 0025756469 scopus 로고
    • Incidence of parenchymal liver diseases in Denmark, 1981 to 1985: Analysis of hospitalization registry data. The Danish Association for the Study of the Liver
    • Almdal TP, Sorensen TI. Incidence of parenchymal liver diseases in Denmark, 1981 to 1985: analysis of hospitalization registry data. The Danish Association for the Study of the Liver. Hepatology 13, 650-655 (1991).
    • (1991) Hepatology , vol.13 , pp. 650-655
    • Almdal, T.P.1    Sorensen, T.I.2
  • 18
    • 0027427843 scopus 로고
    • The increased risk of hospitalizations for acute liver injury in a population with exposure to multiple drugs
    • Perez Gutthann S, Garcia Rodriguez LA. The increased risk of hospitalizations for acute liver injury in a population with exposure to multiple drugs. Epidemiology 4, 496-501 (1993).
    • (1993) Epidemiology , vol.4 , pp. 496-501
    • Perez Gutthann, S.1    Garcia Rodriguez, L.A.2
  • 19
    • 0027494633 scopus 로고
    • Acute liver disease associated with erythromycins, sulfonamides, and tetracyclines
    • Carson JL, Strom BL, Duff A et al. Acute liver disease associated with erythromycins, sulfonamides, and tetracyclines. Ann. Intern. Med. 119, 576-583 (1993).
    • (1993) Ann. Intern. Med , vol.119 , pp. 576-583
    • Carson, J.L.1    Strom, B.L.2    Duff, A.3
  • 20
    • 16044363694 scopus 로고    scopus 로고
    • Clinical hepatology: Profile of an urban, hospital-based practice
    • Byron D, Minuk GY. Clinical hepatology: profile of an urban, hospital-based practice. Hepatology 24, 813-815 (1996).
    • (1996) Hepatology , vol.24 , pp. 813-815
    • Byron, D.1    Minuk, G.Y.2
  • 21
    • 1842364875 scopus 로고    scopus 로고
    • A review of epidemiologic research on drug-induced acute liver injury using the general practice research data base in the United Kingdom
    • Garcia Rodriguez LA, Ruigomez A, Jick H. A review of epidemiologic research on drug-induced acute liver injury using the general practice research data base in the United Kingdom. Pharmacotherapy 17, 721-728 (1997).
    • (1997) Pharmacotherapy , vol.17 , pp. 721-728
    • Garcia Rodriguez, L.A.1    Ruigomez, A.2    Jick, H.3
  • 22
    • 0032795414 scopus 로고    scopus 로고
    • Descriptive epidemiology of acute liver enzyme abnormalities in the general population of central Massachusetts
    • Duh MS, Walker AM, Kronlund KH Jr. Descriptive epidemiology of acute liver enzyme abnormalities in the general population of central Massachusetts. Pharmacoepidemiol. Drug Saf. 8, 275-283 (1999).
    • (1999) Pharmacoepidemiol. Drug Saf , vol.8 , pp. 275-283
    • Duh, M.S.1    Walker, A.M.2    Kronlund Jr., K.H.3
  • 25
    • 0026755976 scopus 로고
    • Drug-induced hepatic injury: An analysis of 1100 cases reported to the Danish Committee on Adverse Drug Reactions between 1978 and 1987
    • Friis H, Andreasen PB. Drug-induced hepatic injury: an analysis of 1100 cases reported to the Danish Committee on Adverse Drug Reactions between 1978 and 1987. J. Intern. Med. 232, 133-138 (1992).
    • (1992) J. Intern. Med , vol.232 , pp. 133-138
    • Friis, H.1    Andreasen, P.B.2
  • 26
    • 0029800092 scopus 로고    scopus 로고
    • Drug-associated hepatic reactions in New Zealand: 21 years experience
    • Pillans PI. Drug-associated hepatic reactions in New Zealand: 21 years experience. NZ Med. J. 109, 315-319 (1996).
    • (1996) NZ Med. J , vol.109 , pp. 315-319
    • Pillans, P.I.1
  • 27
    • 24744438422 scopus 로고    scopus 로고
    • Fulminant drug-induced hepatic failure leading to death or liver transplantation in Sweden
    • Björnsson E, Jerlstad P, Bergquist A, Olsson R. Fulminant drug-induced hepatic failure leading to death or liver transplantation in Sweden. Scand. J. Gastroenterol. 40, 1095-1101 (2005).
    • (2005) Scand. J. Gastroenterol , vol.40 , pp. 1095-1101
    • Björnsson, E.1    Jerlstad, P.2    Bergquist, A.3    Olsson, R.4
  • 28
    • 0036323793 scopus 로고    scopus 로고
    • Incidence of drug-induced hepatic injuries: A French population-based study
    • Sgro C, Clinard F, Ouazir K et al. Incidence of drug-induced hepatic injuries: a French population-based study. Hepatology 36, 451-455 (2002).
    • (2002) Hepatology , vol.36 , pp. 451-455
    • Sgro, C.1    Clinard, F.2    Ouazir, K.3
  • 29
    • 0035056827 scopus 로고    scopus 로고
    • The causes of obvious jaundice in South West Wales: 2000
    • Whitehead MW, Hainsworth I, Kingham JGC. The causes of obvious jaundice in South West Wales: 2000. Gut 48, 409-413 (2001).
    • (2001) Gut , vol.48 , pp. 409-413
    • Whitehead, M.W.1    Hainsworth, I.2    Kingham, J.G.C.3
  • 30
    • 0037261365 scopus 로고    scopus 로고
    • Severe jaundice in Sweden in the new millennium: Causes, investigations, treatment and prognosis
    • Björnsson E, Ismael S, Nejdet S, Kilander A. Severe jaundice in Sweden in the new millennium: causes, investigations, treatment and prognosis. Scand. J. Gastroenterol. 38, 86-94 (2003).
    • (2003) Scand. J. Gastroenterol , vol.38 , pp. 86-94
    • Björnsson, E.1    Ismael, S.2    Nejdet, S.3    Kilander, A.4
  • 31
    • 33847251560 scopus 로고    scopus 로고
    • Etiology of new-onset jaundice: How often is it caused by idiosyncratic drug-induced liver injury in the United States?
    • Vuppalanchi R, Liangpunsakul S, Chalasani N. Etiology of new-onset jaundice: how often is it caused by idiosyncratic drug-induced liver injury in the United States? Am. J. Gastroenterol. 102, 558-556 (2007).
    • (2007) Am. J. Gastroenterol , vol.102 , pp. 558-556
    • Vuppalanchi, R.1    Liangpunsakul, S.2    Chalasani, N.3
  • 32
    • 0032966067 scopus 로고    scopus 로고
    • A prospective study of the causes of notably raised aspartate aminotransferase of liver origin
    • Whitehead MW, Hawkes ND, Hainsworth I, Kingham JGC. A prospective study of the causes of notably raised aspartate aminotransferase of liver origin. Gut 45, 129-133 (1999).
    • (1999) Gut , vol.45 , pp. 129-133
    • Whitehead, M.W.1    Hawkes, N.D.2    Hainsworth, I.3    Kingham, J.G.C.4
  • 33
    • 0033729631 scopus 로고    scopus 로고
    • Detection and incidence of drug-induced liver injuries in hospital: A prospective analysis from laboratory signals
    • Bagheri H, Michel F, Lapeyre-Mestre M et al. Detection and incidence of drug-induced liver injuries in hospital: a prospective analysis from laboratory signals. Br. J. Clin. Pharmacol. 50, 479-484 (2000).
    • (2000) Br. J. Clin. Pharmacol , vol.50 , pp. 479-484
    • Bagheri, H.1    Michel, F.2    Lapeyre-Mestre, M.3
  • 34
    • 18744395784 scopus 로고    scopus 로고
    • Incidence of drug-induced liver injury in medical inpatients
    • Meier Y, Cavallaro M, Roos M et al. Incidence of drug-induced liver injury in medical inpatients. Eur. J. Clin. Pharmacol. 61, 135-143 (2005).
    • (2005) Eur. J. Clin. Pharmacol , vol.61 , pp. 135-143
    • Meier, Y.1    Cavallaro, M.2    Roos, M.3
  • 35
    • 0036844835 scopus 로고    scopus 로고
    • the Grup d'Estudi Multicentric d'Hepatotoxicitat Aguda de Barcelona (GEMHAB). Prospective surveillance of acute serious liver disease unrelated to infectious, obstructive, or metabolic diseases: Epidemiological and clinical features, and exposure to drugs
    • Ibáñez L, Pérez E, Vidal X, Laporte JR, the Grup d'Estudi Multicentric d'Hepatotoxicitat Aguda de Barcelona (GEMHAB). Prospective surveillance of acute serious liver disease unrelated to infectious, obstructive, or metabolic diseases: epidemiological and clinical features, and exposure to drugs. J. Hepatol. 37, 592-600 (2002).
    • (2002) J. Hepatol , vol.37 , pp. 592-600
    • Ibáñez, L.1    Pérez, E.2    Vidal, X.3    Laporte, J.R.4
  • 37
    • 3142557936 scopus 로고    scopus 로고
    • Acute and clinically relevant drug-induced liver injury: A population based case-control study
    • De Abajo FJ, Montero D, Madurga M, Garcia Rodriguez LA. Acute and clinically relevant drug-induced liver injury: a population based case-control study. Br. J. Clin. Pharmacol. 58, 71-80 (2004).
    • (2004) Br. J. Clin. Pharmacol , vol.58 , pp. 71-80
    • De Abajo, F.J.1    Montero, D.2    Madurga, M.3    Garcia Rodriguez, L.A.4
  • 38
    • 34147150458 scopus 로고    scopus 로고
    • Drug-induced liver injury network (DILIN). Prospective study: Initial results
    • S
    • Chalasani N, Fontana R, Watkins PB et al. Drug-induced liver injury network (DILIN). Prospective study: initial results. Am. J. Gastroenterol. 101, S168 (2006).
    • (2006) Am. J. Gastroenterol , vol.101 , pp. 168
    • Chalasani, N.1    Fontana, R.2    Watkins, P.B.3
  • 39
    • 33947204690 scopus 로고    scopus 로고
    • Mitochondrial abnormalities. A link to idiosyncratic drug hepatotoxicity?
    • Boelsterli UA, Lim PLK. Mitochondrial abnormalities. A link to idiosyncratic drug hepatotoxicity? Toxicol. Appl. Pharmacol. 220 92-107 (2007).
    • (2007) Toxicol. Appl. Pharmacol , vol.220 , pp. 92-107
    • Boelsterli, U.A.1    Lim, P.L.K.2
  • 40
    • 20844444779 scopus 로고    scopus 로고
    • Idiosyncratic drug hepatotoxicity
    • Kaplowitz N. Idiosyncratic drug hepatotoxicity. Nat. Rev. Drug Discov. 4, 489-499 (2005).
    • (2005) Nat. Rev. Drug Discov , vol.4 , pp. 489-499
    • Kaplowitz, N.1
  • 41
    • 18844373318 scopus 로고    scopus 로고
    • Role of metabolism in drug-induced idiosyncratic hepatotoxicity
    • Walgren JL, Mitchell MD, Thompson DC. Role of metabolism in drug-induced idiosyncratic hepatotoxicity. Crit. Rev. Toxicol. 35, 325-361 (2005).
    • (2005) Crit. Rev. Toxicol , vol.35 , pp. 325-361
    • Walgren, J.L.1    Mitchell, M.D.2    Thompson, D.C.3
  • 42
    • 0029160914 scopus 로고
    • Role of reactive metabolites in drug-induced hepatitis
    • Pessayre D. Role of reactive metabolites in drug-induced hepatitis. J. Hepatol. 23 (1 Suppl.), 16-24 (1995).
    • (1995) J. Hepatol , vol.23 , Issue.1 SUPPL. , pp. 16-24
    • Pessayre, D.1
  • 43
    • 0030630618 scopus 로고    scopus 로고
    • Plasma membrane cytochromes P450 as neoantigens and autoimmune targets in drug-induced hepatitis
    • Robin MA, Le Roy M, Descatoire V, Pessayre D. Plasma membrane cytochromes P450 as neoantigens and autoimmune targets in drug-induced hepatitis. J. Hepatol. 26(1 Suppl.), 23-30 (1997).
    • (1997) J. Hepatol , vol.26 , Issue.1 SUPPL. , pp. 23-30
    • Robin, M.A.1    Le Roy, M.2    Descatoire, V.3    Pessayre, D.4
  • 44
    • 0031921972 scopus 로고    scopus 로고
    • Steatohepatitis-inducing drugs cause mitochondrial dysfunction and lipid peroxidation in rat hepatocytes
    • Berson A, De Beco V, Letteron P et al. Steatohepatitis-inducing drugs cause mitochondrial dysfunction and lipid peroxidation in rat hepatocytes. Gastroenterology 114, 764-774 (1998).
    • (1998) Gastroenterology , vol.114 , pp. 764-774
    • Berson, A.1    De Beco, V.2    Letteron, P.3
  • 46
    • 0032878643 scopus 로고    scopus 로고
    • Withdrawal of life support, altruistic suicide, fratricidal killing and euthanasia by lymphocytes: Different forms of drug-induced hepatic apoptosis
    • Pessayre D, Haouzi D, Fau D, Robin MA, Mansouri A, Berson A. Withdrawal of life support, altruistic suicide, fratricidal killing and euthanasia by lymphocytes: different forms of drug-induced hepatic apoptosis. J. Hepatol. 31(4), 760-770 (1999).
    • (1999) J. Hepatol , vol.31 , Issue.4 , pp. 760-770
    • Pessayre, D.1    Haouzi, D.2    Fau, D.3    Robin, M.A.4    Mansouri, A.5    Berson, A.6
  • 47
    • 9644289366 scopus 로고    scopus 로고
    • Innate immune system plays a critical role in determining the progression and severity of acetaminophen hepatotoxicity
    • Liu ZX, Govindarajan S, Kaplowitz N. Innate immune system plays a critical role in determining the progression and severity of acetaminophen hepatotoxicity. Gastroenterology 127, 1760-1774 (2004).
    • (2004) Gastroenterology , vol.127 , pp. 1760-1774
    • Liu, Z.X.1    Govindarajan, S.2    Kaplowitz, N.3
  • 50
    • 33644514993 scopus 로고    scopus 로고
    • Liver biology and pathobiology
    • Kaplowitz N. Liver biology and pathobiology. Hepatology 43(Suppl. 1), S235-S238 (2006).
    • (2006) Hepatology , vol.43 , Issue.SUPPL. 1
    • Kaplowitz, N.1
  • 51
    • 15844419903 scopus 로고    scopus 로고
    • Risk of acute liver injury associated with the combination of amoxicllin and clavulanic acid
    • Garcia Rodriguez LA, Stricker BH, Zimmermann HI. Risk of acute liver injury associated with the combination of amoxicllin and clavulanic acid. Arch. Intern. Med. 156, 1327-1332 (1996).
    • (1996) Arch. Intern. Med , vol.156 , pp. 1327-1332
    • Garcia Rodriguez, L.A.1    Stricker, B.H.2    Zimmermann, H.I.3
  • 52
    • 22244492630 scopus 로고    scopus 로고
    • Isoniazid hepatotoxicity associated with treatment of latent tuberculosis infection: A 7-year evaluation from a public health tuberculosis clinic
    • Fountain FF, Tolley E, Chrisman CR, Self TH. Isoniazid hepatotoxicity associated with treatment of latent tuberculosis infection: a 7-year evaluation from a public health tuberculosis clinic. Chest 128, 116-123 (2005).
    • (2005) Chest , vol.128 , pp. 116-123
    • Fountain, F.F.1    Tolley, E.2    Chrisman, C.R.3    Self, T.H.4
  • 54
    • 33750610841 scopus 로고    scopus 로고
    • Hepatobiliary transporters and drug-induced cholestasis
    • Pauli-Magnus C, Meier PJ. Hepatobiliary transporters and drug-induced cholestasis. Hepatology 4, 778-787 (2006).
    • (2006) Hepatology , vol.4 , pp. 778-787
    • Pauli-Magnus, C.1    Meier, P.J.2
  • 55
    • 4544363071 scopus 로고    scopus 로고
    • Liver transplantation for acute liver failure from drug induced liver injury in the United States
    • Russo MW, Galanko JA, Shrestha R, Fried MW, Watkins P. Liver transplantation for acute liver failure from drug induced liver injury in the United States. Liver Transpl. 10, 1018-1023 (2004).
    • (2004) Liver Transpl , vol.10 , pp. 1018-1023
    • Russo, M.W.1    Galanko, J.A.2    Shrestha, R.3    Fried, M.W.4    Watkins, P.5
  • 57
    • 0035393428 scopus 로고    scopus 로고
    • Risk factors for hepatotoxicity in patients treated with highly active antiretroviral therapy
    • Bonfanti P, Landonio S, Ricci E et al. Risk factors for hepatotoxicity in patients treated with highly active antiretroviral therapy. J. Acquir. Immune Defic. Syndr. 27, 316-318 (2001).
    • (2001) J. Acquir. Immune Defic. Syndr , vol.27 , pp. 316-318
    • Bonfanti, P.1    Landonio, S.2    Ricci, E.3
  • 58
    • 34247597281 scopus 로고    scopus 로고
    • Psoriasis patients with diabetes mellitus type 2 are at high risk of developing liver fibrosis during methotrexate treatment
    • Rosenberg P, Urwitz H, Johansson A et al. Psoriasis patients with diabetes mellitus type 2 are at high risk of developing liver fibrosis during methotrexate treatment. J. Hepatol. 46, 1111-1118 (2007).
    • (2007) J. Hepatol , vol.46 , pp. 1111-1118
    • Rosenberg, P.1    Urwitz, H.2    Johansson, A.3
  • 59
    • 2142645901 scopus 로고    scopus 로고
    • Are patients with elevated liver tests at increased risk of drug-induced liver injury?
    • Russo WM, Watkins PB. Are patients with elevated liver tests at increased risk of drug-induced liver injury? Gastroenterology 126, 1477-1480 (2004).
    • (2004) Gastroenterology , vol.126 , pp. 1477-1480
    • Russo, W.M.1    Watkins, P.B.2
  • 60
    • 0013045289 scopus 로고    scopus 로고
    • The rational use of potentially hepatotoxic medications in patients with underlying liver disease
    • Lewis JH. The rational use of potentially hepatotoxic medications in patients with underlying liver disease. Expert Opin. Drug Saf. 1, 159-172 (2002).
    • (2002) Expert Opin. Drug Saf , vol.1 , pp. 159-172
    • Lewis, J.H.1
  • 61
    • 2142768218 scopus 로고    scopus 로고
    • Patients with elevated liver enzymes are not at higher risk for statin hepatotoxicity
    • Chalasani N, Aljadhey H, Kesterson J, Murray MD, Hall SD. Patients with elevated liver enzymes are not at higher risk for statin hepatotoxicity. Gastroenterology 126, 1287-1292 (2004).
    • (2004) Gastroenterology , vol.126 , pp. 1287-1292
    • Chalasani, N.1    Aljadhey, H.2    Kesterson, J.3    Murray, M.D.4    Hall, S.D.5
  • 62
    • 0021146282 scopus 로고
    • Impaired oxidation of debrisoquine in patients with perhexiline liver injury
    • Morgan MY, Reshef R, Shah RR, Oates NS, Smith RL, Sherlock S. Impaired oxidation of debrisoquine in patients with perhexiline liver injury. Gut 25, 1057-1064 (1984).
    • (1984) Gut , vol.25 , pp. 1057-1064
    • Morgan, M.Y.1    Reshef, R.2    Shah, R.R.3    Oates, N.S.4    Smith, R.L.5    Sherlock, S.6
  • 63
    • 0025572192 scopus 로고
    • Hydroxylation polymorphisms of debrisoquine and mephenytoin in European populations
    • Alvan G, Bechtel P, Iselius L, Gundert-Remy U. Hydroxylation polymorphisms of debrisoquine and mephenytoin in European populations. Eur. J. Clin. Pharmacol. 39, 533-537 (1990).
    • (1990) Eur. J. Clin. Pharmacol , vol.39 , pp. 533-537
    • Alvan, G.1    Bechtel, P.2    Iselius, L.3    Gundert-Remy, U.4
  • 64
    • 0028625485 scopus 로고
    • Possible association between poor metabolism of mephenytoin and hepatotoxicity caused by Atrium, a fixed combination preparation containing phenobarbital, febarbamate and difebarbamate
    • Horsmans Y, Lannes D, Pessayre D, Larrey D. Possible association between poor metabolism of mephenytoin and hepatotoxicity caused by Atrium, a fixed combination preparation containing phenobarbital, febarbamate and difebarbamate. J. Hepatol. 21, 1075-1079 (1994).
    • (1994) J. Hepatol , vol.21 , pp. 1075-1079
    • Horsmans, Y.1    Lannes, D.2    Pessayre, D.3    Larrey, D.4
  • 66
    • 0037380862 scopus 로고    scopus 로고
    • Cytochrome P450 2E1 genotype and the susceptibility to antituberculosis drug-induced hepatitis
    • Huang YS, Chern HD, Su WJ et al. Cytochrome P450 2E1 genotype and the susceptibility to antituberculosis drug-induced hepatitis. Hepatology 37, 924-930 (2003).
    • (2003) Hepatology , vol.37 , pp. 924-930
    • Huang, Y.S.1    Chern, H.D.2    Su, W.J.3
  • 67
    • 34249284163 scopus 로고    scopus 로고
    • Genetic polymorphisms of manganese superoxide dismutase, NAD(P)H: Quinone oxidoreductase, glutathione S-transferase M1 and T1 and the susceptibility to drug-induced liver injury
    • Huang YS, Su WJ, Huang YH et al. Genetic polymorphisms of manganese superoxide dismutase, NAD(P)H: quinone oxidoreductase, glutathione S-transferase M1 and T1 and the susceptibility to drug-induced liver injury. J. Hepatol. 47, 128-134 (2007).
    • (2007) J. Hepatol , vol.47 , pp. 128-134
    • Huang, Y.S.1    Su, W.J.2    Huang, Y.H.3
  • 68
    • 0034112853 scopus 로고    scopus 로고
    • Combined glutathione-S-transferase M1 and T1 genetic polymorphism and tacrine hepatotoxicity
    • Simon T, Becquemont L, Mary-Krause M et al. Combined glutathione-S-transferase M1 and T1 genetic polymorphism and tacrine hepatotoxicity. Clin. Pharmacol. Ther. 67, 432-437 (2000).
    • (2000) Clin. Pharmacol. Ther , vol.67 , pp. 432-437
    • Simon, T.1    Becquemont, L.2    Mary-Krause, M.3
  • 69
    • 0038708252 scopus 로고    scopus 로고
    • A study to survey susceptible genetic factors responsible for troglitazone-associated hepatotoxicity in Japanese patients with type 2 diabetes mellitus
    • Watanabe I, Tomita A, Shimizu M et al. A study to survey susceptible genetic factors responsible for troglitazone-associated hepatotoxicity in Japanese patients with type 2 diabetes mellitus. Clin. Pharmacol. Ther. 73, 435-455 (2003).
    • (2003) Clin. Pharmacol. Ther , vol.73 , pp. 435-455
    • Watanabe, I.1    Tomita, A.2    Shimizu, M.3
  • 70
    • 34248594127 scopus 로고    scopus 로고
    • Validation of the association between single nucleotide polymorphisms or haplotypes and responses to disease-modifying antirheumatic drugs in patients with rheumatoid arthritis: A proposal for prospective pharmacogenomic study in clinical practice
    • Taniguchi A, Urano W, Tanaka E et al. Validation of the association between single nucleotide polymorphisms or haplotypes and responses to disease-modifying antirheumatic drugs in patients with rheumatoid arthritis: a proposal for prospective pharmacogenomic study in clinical practice. Pharmacogenet. Genomics 17, 383-390 (2007).
    • (2007) Pharmacogenet. Genomics , vol.17 , pp. 383-390
    • Taniguchi, A.1    Urano, W.2    Tanaka, E.3
  • 71
    • 33846230114 scopus 로고    scopus 로고
    • Genetic susceptibility to diclofenac-induced hepatotoxicity: Contribution of UGT2B7, CYP2C8, and ABCC2 genotypes
    • Daly AK, Aithal GP, Leathart JBS, Swainsbury RA, Dang TS, Day CP. Genetic susceptibility to diclofenac-induced hepatotoxicity: contribution of UGT2B7, CYP2C8, and ABCC2 genotypes. Gastroenterology 132, 272-281 (2007).
    • (2007) Gastroenterology , vol.132 , pp. 272-281
    • Daly, A.K.1    Aithal, G.P.2    Leathart, J.B.S.3    Swainsbury, R.A.4    Dang, T.S.5    Day, C.P.6
  • 72
    • 2342541211 scopus 로고    scopus 로고
    • Hepatic adducts, circulating antibodies, and cytokine polymorphisms in patients with diclofenac hepatotoxicity
    • Aithal GP, Ramsay L, Daly AK et al. Hepatic adducts, circulating antibodies, and cytokine polymorphisms in patients with diclofenac hepatotoxicity. Hepatology 39, 1430-1440 (2004).
    • (2004) Hepatology , vol.39 , pp. 1430-1440
    • Aithal, G.P.1    Ramsay, L.2    Daly, A.K.3
  • 73
    • 49249099592 scopus 로고    scopus 로고
    • Genetic polymorphisms of IL- 10, IL-4 and TNF α and susceptibility to develop drug-induced idiosyncratic liver injury (DILI)
    • Pachkoria K, Crespo E, Ruiz-Cabello F et al. Genetic polymorphisms of IL- 10, IL-4 and TNF α and susceptibility to develop drug-induced idiosyncratic liver injury (DILI). Hepatology 46(Suppl.), 809A (2007).
    • (2007) Hepatology , vol.46 , Issue.SUPPL.
    • Pachkoria, K.1    Crespo, E.2    Ruiz-Cabello, F.3
  • 74
    • 2542627509 scopus 로고    scopus 로고
    • HLA class II genotype influences the type of liver injury in drug-induced idiosyncratic liver disease
    • Andrade RJ, Lucena MI, Alonso A et al. HLA class II genotype influences the type of liver injury in drug-induced idiosyncratic liver disease. Hepatology 39, 1603-1612 (2004).
    • (2004) Hepatology , vol.39 , pp. 1603-1612
    • Andrade, R.J.1    Lucena, M.I.2    Alonso, A.3
  • 75
    • 44049102035 scopus 로고    scopus 로고
    • Genome-wide pharmacogenetic investigation of a hepatic adverse event without clinical signs of immunopathology suggests an underlying immune pathogenesis
    • DOI: 10.1038/sj.tpj.6500458 , Epub ahead of print
    • Kindmark A, Jawaid A, Harbron CG et al. Genome-wide pharmacogenetic investigation of a hepatic adverse event without clinical signs of immunopathology suggests an underlying immune pathogenesis. Pharmacogenomics J. DOI: 10.1038/sj.tpj.6500458 (2007) (Epub ahead of print).
    • (2007) Pharmacogenomics J
    • Kindmark, A.1    Jawaid, A.2    Harbron, C.G.3
  • 76
    • 0025227871 scopus 로고
    • Criteria of drug-induced liver disorders. Report of an International Consensus Meeting
    • Benichou C. Criteria of drug-induced liver disorders. Report of an International Consensus Meeting. J. Hepatol. 11, 272-276 (1990).
    • (1990) J. Hepatol , vol.11 , pp. 272-276
    • Benichou, C.1
  • 77
    • 0034051526 scopus 로고    scopus 로고
    • Drug-induced liver diseases
    • 32Suppi. 1
    • Larrey D. Drug-induced liver diseases. J. Hepatol. 32(Suppi. 1), 77-88 (2000).]
    • (2000) J. Hepatol , pp. 77-88
    • Larrey, D.1
  • 78
    • 0035986526 scopus 로고    scopus 로고
    • Drug hepatotoxicity
    • Goodman ZD. Drug hepatotoxicity. Clin. Liver Dis. 6, 381-397 (2002).
    • (2002) Clin. Liver Dis , vol.6 , pp. 381-397
    • Goodman, Z.D.1
  • 79
  • 80
    • 23044473682 scopus 로고    scopus 로고
    • Outcome and prognostic markers in severe drug-induced liver disease
    • Björnsson E, Olsson R. Outcome and prognostic markers in severe drug-induced liver disease. Hepatology 42, 481-489 (2005).
    • (2005) Hepatology , vol.42 , pp. 481-489
    • Björnsson, E.1    Olsson, R.2
  • 81
    • 33644887200 scopus 로고    scopus 로고
    • Clinical characteristics and prognostic markers in disulfiram-induced liver injury
    • Björnsson E, Nordlinder H, Olsson R. Clinical characteristics and prognostic markers in disulfiram-induced liver injury. J. Hepatol. 44, 791-797 (2006).
    • (2006) J. Hepatol , vol.44 , pp. 791-797
    • Björnsson, E.1    Nordlinder, H.2    Olsson, R.3
  • 82
    • 34249803204 scopus 로고    scopus 로고
    • The impact of cosinophilia. and hepatic necrosis on prognosis in patients with drug-induced liver injury
    • Björnsson E, Kalaitzakis E, Olsson R. The impact of cosinophilia. and hepatic necrosis on prognosis in patients with drug-induced liver injury. Aliment. Pharmacol. Ther. 25, 1411-1421 (2007).
    • (2007) Aliment. Pharmacol. Ther , vol.25 , pp. 1411-1421
    • Björnsson, E.1    Kalaitzakis, E.2    Olsson, R.3
  • 83
    • 13444305469 scopus 로고    scopus 로고
    • Idiosyncratic liver injury. challenges and approaches
    • Watkins PB. Idiosyncratic liver injury. challenges and approaches. Toxicol. Pathol. 33, 1-5 (2005).
    • (2005) Toxicol. Pathol , vol.33 , pp. 1-5
    • Watkins, P.B.1
  • 84
    • 33750632721 scopus 로고    scopus 로고
    • Determinants ofthe clinical expression of amoxicillin-clavulanate hepatotoxicity: A prospective series from Spain
    • Lucena MI, Andrade RJ, Fernandez MC et al. Determinants ofthe clinical expression of amoxicillin-clavulanate hepatotoxicity: a prospective series from Spain. Hepatology 44, 850-856 (2006).
    • (2006) Hepatology , vol.44 , pp. 850-856
    • Lucena, M.I.1    Andrade, R.J.2    Fernandez, M.C.3
  • 85
    • 33845666885 scopus 로고    scopus 로고
    • Outcome of acute idiosyncratic drug-induced liver injury: Long-term follow-up in a hepatotoxicity registry
    • Andrade RJ, Lucena MI, Kaplowitz N et al. Outcome of acute idiosyncratic drug-induced liver injury: long-term follow-up in a hepatotoxicity registry. Hepatology 44, 1581-1588 (2006).
    • (2006) Hepatology , vol.44 , pp. 1581-1588
    • Andrade, R.J.1    Lucena, M.I.2    Kaplowitz, N.3
  • 87
    • 0033547542 scopus 로고    scopus 로고
    • Accuracy of hepatic adverse drug reaction reporting in one English health region
    • Aithal GP, Rawlins MD, Day CP. Accuracy of hepatic adverse drug reaction reporting in one English health region. Br. Med. J. 319, 1541 (1999).
    • (1999) Br. Med. J , vol.319 , pp. 1541
    • Aithal, G.P.1    Rawlins, M.D.2    Day, C.P.3
  • 88
    • 0034950046 scopus 로고    scopus 로고
    • Drug-induced liver disorders: Implications for drug development and regulation
    • Kaplowitz N. Drug-induced liver disorders: implications for drug development and regulation. Drug Saf. 24, 483-490 (2001).
    • (2001) Drug Saf , vol.24 , pp. 483-490
    • Kaplowitz, N.1
  • 90
    • 0035192830 scopus 로고    scopus 로고
    • Causality assessment versus guilt-by-association in drug hepatotoxicity
    • Kaplowitz N. Causality assessment versus guilt-by-association in drug hepatotoxicity. Hepatology 33, 308-310 (2001).
    • (2001) Hepatology , vol.33 , pp. 308-310
    • Kaplowitz, N.1
  • 91
    • 13444273562 scopus 로고    scopus 로고
    • Recognizing drug-induced liver injury: Current problems, possible solutions
    • Lee WM, Senior JR. Recognizing drug-induced liver injury: current problems, possible solutions. Toxicol. Pathol. 33, 155-164 (2005).
    • (2005) Toxicol. Pathol , vol.33 , pp. 155-164
    • Lee, W.M.1    Senior, J.R.2
  • 93
    • 0034876150 scopus 로고    scopus 로고
    • Liver biopsy in elevated liver function tests? An old question revisited
    • Bianchi L. Liver biopsy in elevated liver function tests? An old question revisited. J. Hepatol. 35, 290-294 (2001).
    • (2001) J. Hepatol , vol.35 , pp. 290-294
    • Bianchi, L.1
  • 94
    • 0033897691 scopus 로고    scopus 로고
    • Chronic liver injury related with the use of bentazepam: An unusual instance of benzodiazepine hepatotoxicity
    • Andrade RJ, Lucena MI, Aguilar J et al. Chronic liver injury related with the use of bentazepam: an unusual instance of benzodiazepine hepatotoxicity. Dig. Dis. Sci. 45, 1400-1404 (2000).
    • (2000) Dig. Dis. Sci , vol.45 , pp. 1400-1404
    • Andrade, R.J.1    Lucena, M.I.2    Aguilar, J.3
  • 95
    • 0026585530 scopus 로고
    • Drug-induced prolonged cholestasis in adults: A histological semiquantitative study demonstrating progressive ductopenia
    • Degott C, Feldmann G, Larrey D et al. Drug-induced prolonged cholestasis in adults: a histological semiquantitative study demonstrating progressive ductopenia. Hepatology 15, 244-251(1992).
    • (1992) Hepatology , vol.15 , pp. 244-251
    • Degott, C.1    Feldmann, G.2    Larrey, D.3
  • 96
    • 0033045249 scopus 로고    scopus 로고
    • The natural history of histologically proved drug induced liver disease
    • Aithal PG, Day CP. The natural history of histologically proved drug induced liver disease. Gut 44, 731-735 (1999).
    • (1999) Gut , vol.44 , pp. 731-735
    • Aithal, P.G.1    Day, C.P.2
  • 98
    • 0027362542 scopus 로고
    • Causality assessment of adverse reactions to drugs I. A novel method based on the conclusions of international consensus meetings: Application to drug-induced liver injuries
    • Danan G, Bénichou C. Causality assessment of adverse reactions to drugs I. A novel method based on the conclusions of international consensus meetings: application to drug-induced liver injuries. J. Clin. Epidemiol. 46, 1323-1330. (1993).
    • (1993) J. Clin. Epidemiol , vol.46 , pp. 1323-1330
    • Danan, G.1    Bénichou, C.2
  • 99
    • 0030865914 scopus 로고    scopus 로고
    • Development and validation of a clinical scale for the diagnosis ofdrug-induced hepatitis
    • Maria V, Victorino R. Development and validation of a clinical scale for the diagnosis ofdrug-induced hepatitis. Hepatology 26, 664-669 (1997).
    • (1997) Hepatology , vol.26 , pp. 664-669
    • Maria, V.1    Victorino, R.2
  • 101
    • 0019799332 scopus 로고
    • A method for estimating the probability of adverse drug reactions
    • Naranjo CA,.Busto U, Sellers EM et al. A method for estimating the probability of adverse drug reactions. Clin. Pharmacol. Ther. 30, 239-245 (1981).
    • (1981) Clin. Pharmacol. Ther , vol.30 , pp. 239-245
    • Naranjo, C.A.1    Busto, U.2    Sellers, E.M.3
  • 102
    • 49249094826 scopus 로고    scopus 로고
    • Comparison of two clinical scales in the causality assessment of drug induced liver disease
    • S
    • Garcia-Cort-aces M, Pachkoria K, Lucena MI et al. Comparison of two clinical scales in the causality assessment of drug induced liver disease. J. Hepatol. 44(Suppl. 2), S253 (2006).
    • (2006) J. Hepatol , vol.44 , Issue.SUPPL. 2 , pp. 253
    • Garcia-Cort-aces, M.1    Pachkoria, K.2    Lucena, M.I.3
  • 103
    • 0033652840 scopus 로고    scopus 로고
    • Assessing causality in drug-induced liver injury
    • Lee WM. Assessing causality in drug-induced liver injury. J. Hepatol. 33, 1003-1005 (2000).
    • (2000) J. Hepatol , vol.33 , pp. 1003-1005
    • Lee, W.M.1
  • 104
    • 49249133031 scopus 로고    scopus 로고
    • A prospective study of the reliability of the RUCAM for assessing causality in drug-induced liver injury
    • Rochon J, Seeff LB, Fontana RJ et al. A prospective study of the reliability of the RUCAM for assessing causality in drug-induced liver injury. Hepatology 46(Suppl. 1), 811A (2007).
    • (2007) Hepatology , vol.46 , Issue.SUPPL. 1
    • Rochon, J.1    Seeff, L.B.2    Fontana, R.J.3
  • 105
    • 0242690497 scopus 로고    scopus 로고
    • Assessment of 287 Japanese cases of drug induced liver injury by the diagnostic scale of the International Consensus Meeting
    • Takikawa H, Takamori Y, Kumagi T et al. Assessment of 287 Japanese cases of drug induced liver injury by the diagnostic scale of the International Consensus Meeting. Hepatol. Res. 27, 192-195 (2003).
    • (2003) Hepatol. Res , vol.27 , pp. 192-195
    • Takikawa, H.1    Takamori, Y.2    Kumagi, T.3
  • 106
    • 10644251758 scopus 로고    scopus 로고
    • Validity study of a new diagnostic scale for drug-induced liver injury in Japan-comparison with two previous scales
    • Watanabe M, Shibuya A. Validity study of a new diagnostic scale for drug-induced liver injury in Japan-comparison with two previous scales. Hepatol. Res. 30, 148-154 (2004).
    • (2004) Hepatol. Res , vol.30 , pp. 148-154
    • Watanabe, M.1    Shibuya, A.2
  • 107
    • 0028811644 scopus 로고
    • A 7-year experience of severe acetaminophen-induced hepatotoxicity (1987-1993)
    • Makin AJ, Wendon J, Williams R. A 7-year experience of severe acetaminophen-induced hepatotoxicity (1987-1993). Gastroenterology 109, 1907-1916 (1995).
    • (1995) Gastroenterology , vol.109 , pp. 1907-1916
    • Makin, A.J.1    Wendon, J.2    Williams, R.3
  • 108
    • 41849109352 scopus 로고    scopus 로고
    • Intravenous N-acetylcysteine improves spontaneous survival in early stage non-acetaminiphen acute liver failure
    • Lee WM, Rossaro L, Fontana RJ et al. Intravenous N-acetylcysteine improves spontaneous survival in early stage non-acetaminiphen acute liver failure. Hepatology 46(Suppl. 1), 268A (2007).
    • (2007) Hepatology , vol.46 , Issue.SUPPL. 1
    • Lee, W.M.1    Rossaro, L.2    Fontana, R.J.3
  • 109
    • 0035933079 scopus 로고    scopus 로고
    • Effect of L-carnitine treatment for valproate induced hepatotoxicity
    • Bohan TP, Helton E, McDonald I et al. Effect of L-carnitine treatment for valproate induced hepatotoxicity. Neurology 56, 1405-1409 (2001).
    • (2001) Neurology , vol.56 , pp. 1405-1409
    • Bohan, T.P.1    Helton, E.2    McDonald, I.3
  • 110
    • 0025815250 scopus 로고
    • A double-blinded, randomized trial of hydrocortisone in acute hepatic failure. The acute hepatic failure study group
    • Rakela J, Mosley JW, Edwards VM, Govindarajan S, Alpert E. A double-blinded, randomized trial of hydrocortisone in acute hepatic failure. The acute hepatic failure study group. Dig. Dis. Sci. 36, 1223-1228 (1991).
    • (1991) Dig. Dis. Sci , vol.36 , pp. 1223-1228
    • Rakela, J.1    Mosley, J.W.2    Edwards, V.M.3    Govindarajan, S.4    Alpert, E.5
  • 111
    • 0029788999 scopus 로고    scopus 로고
    • Ursodeoxycholic acid for treatment of cholestasis in children on long-term total parenteral nutrition: A pilot study
    • Spagnuolo MI, Iorio R, Vegnente A, Guarino A. Ursodeoxycholic acid for treatment of cholestasis in children on long-term total parenteral nutrition: a pilot study. Gastroenterology 111, 716-719 (1996).
    • (1996) Gastroenterology , vol.111 , pp. 716-719
    • Spagnuolo, M.I.1    Iorio, R.2    Vegnente, A.3    Guarino, A.4
  • 112
    • 0036708294 scopus 로고    scopus 로고
    • Rofecoxib-induced cholestatic hepatitis: Treatment with molecular adsorbent recycling system (MARS)
    • Huster D, Schubert C, Bess F, Mossner J, Caca K. Rofecoxib-induced cholestatic hepatitis: treatment with molecular adsorbent recycling system (MARS). J. Hepatol. 37, 413-414 (2002).
    • (2002) J. Hepatol , vol.37 , pp. 413-414
    • Huster, D.1    Schubert, C.2    Bess, F.3    Mossner, J.4    Caca, K.5


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