Detection and incidence of drug-induced liver injuries in hospital: A prospective analysis from laboratory signals

British Journal of Clinical Pharmacology

Volumn 50, Issue 5, 2000, Pages 479-484

  Bagheri, H ^a   Michel, F ^a   Lapeyre Mestre, M ^a   Lagier, E ^a   Cambus, J P ^a   Valdiguie, P ^a   Montastruc, J L ^a  

^a UNIVERSITÉ DE TOULOUSE   (France)

Author keywords

Adverse drug reactions; Drug induced liver injuries; Laboratory signals; Underreporting rate

Indexed keywords

ALANINE AMINOTRANSFERASE; ALIMEMAZINE; ALKALINE PHOSPHATASE; AMINEPTINE; CHLORPROMAZINE; CLOMIPRAMINE; CLONAZEPAM; CLORAZEPATE; CYPROTERONE ACETATE; DIETHYLSTILBESTROL; FENOFIBRATE; FLUINDIONE; FLUOXETINE; HALOPERIDOL; ISONIAZID; KETOPROFEN; LEVOMEPROMAZINE; PYRAZINAMIDE; QUINAPRIL; RIFAMPICIN; SALAZOSULFAPYRIDINE; TRIMIPRAMINE;

ADULT; ALANINE AMINOTRANSFERASE BLOOD LEVEL; ALKALINE PHOSPHATASE BLOOD LEVEL; ARTICLE; CONTROLLED STUDY; DATA BASE; DISEASE SEVERITY; DRUG WITHDRAWAL; FEMALE; HOSPITAL; HOSPITALIZATION; HUMAN; INCIDENCE; LIVER INJURY; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL;

ADVERSE DRUG REACTION REPORTING SYSTEMS; ALANINE TRANSAMINASE; ALKALINE PHOSPHATASE; CLINICAL PHARMACY INFORMATION SYSTEMS; DATABASES, FACTUAL; FEMALE; HOSPITALS, UNIVERSITY; HUMANS; INCIDENCE; INPATIENTS; LIVER DISEASES; MALE; MIDDLE AGED; PROSPECTIVE STUDIES;

EID: 0033729631     PISSN: 03065251     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2125.2000.00282.x     Document Type: Article

References (32)

1. Drug safety discontinuations in the United Kingdom, the United States, and Spain from 1974 through 1993: A regulatory perspective
2. Hepatotoxicity in drug development: Detection, significance and solutions
3. Drugs and liver. Meeting report
4. A review of epidemiologic research on drug-induced acute liver injury using the General Practice Research Database in the United Kingdom
5. Epidemiology of drug-induced hepatic injury
6. The risk of acute liver injury associated with cimetidine and other acid suppressing anti-ulcer drugs
7. Computerized surveillance of adverse drug events in hospital patients
8. Potential identifiability and preventability of adverse events using information systems
9. Liver test abnormalities
10. Causality assessment of adverse reactions to drugs-I A novel method based on the conclusions of international consensus meetings: Application to drug-induced liver injuries
11. Power and weakness of spontaneous reporting: A probabilistic approach
12. Estimation of under-reporting. Methodological Approaches in Pharmacoepidemiology: Application to Spontaneous Reporting ARME-P
13. Computerized surveillance of adverse drug reactions in hospital: Pilot study
14. Computerized medication monitoring system
15. Development of a computerized adverse drug event monitor. ADE prevention group
16. Systems analysis of adverse drug events
17. The computer-based patient record: The role of the hospital epidemiologist
18. Computerized surveillance of adverse reactions in hospital: Implementation
19. Liver injuries: A prospective study
20. Retrospective analysis of the frequency and recognition of adverse drug reactions by means of automatically recorded laboratory signals
21. Under-reporting of adverse reactions: Estimated base on a spontaneous reporting scheme and a sentinel system
22. The underreporting of adverse drug reactions seen in general practice
23. Ministere des Affaires Sociales, de la Sante et de la Ville. Decret no. 95-278 du 13 mars. Relatif a la pharmacovigilance et modifiant le code de la sante publique
24. Drug-induced liver disease
25. Hepatitis after germander (Teucrium chamaedrys) administration: Another instance of herbal medicine hepatotoxicity
26. Hepatitis induced by traditional Chinese herbs: Possible toxic components