Tempol diminishes cocaine-induced oxidative damage and attenuates the development and expression of behavioral sensitization

Neuroscience

Volumn 155, Issue 3, 2008, Pages 649-658

  Numa, R ^a   Kohen, R ^a   Poltyrev, T ^a   Yaka, R ^a  

^a HEBREW UNIVERSITY OF JERUSALEM   (Israel)

Author keywords

antioxidants; behavioral sensitization; cocaine; oxidative stress; tempol; total antioxidant capacity

Indexed keywords

COCAINE; TEMPOL;

ADOLESCENT; ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ARTICLE; BEHAVIOR CHANGE; CONTROLLED STUDY; DRUG EFFECT; IN VITRO STUDY; IN VIVO STUDY; LOCOMOTION; MALE; NONHUMAN; NUCLEUS ACCUMBENS; OXIDATIVE STRESS; PREFRONTAL CORTEX; PRIORITY JOURNAL; RAT;

ANALYSIS OF VARIANCE; ANIMALS; ANTIOXIDANTS; BEHAVIOR, ANIMAL; BRAIN; COCAINE; CYCLIC N-OXIDES; DOPAMINE UPTAKE INHIBITORS; DRUG INTERACTIONS; LIPID PEROXIDATION; MALE; MALONDIALDEHYDE; MOTOR ACTIVITY; NITRITES; OXIDATION-REDUCTION; RATS; REACTIVE OXYGEN SPECIES; SPIN LABELS; THIOBARBITURIC ACID REACTIVE SUBSTANCES; TIME FACTORS;

EID: 49249100214     PISSN: 03064522     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuroscience.2008.05.058     Document Type: Article

References (53)

1. 2 dismutation. Free Radic Biol Med 42 (2007) 1317-1325
2. Bashkatova V., Meunier J., Maurice T., and Vanin A. Memory impairments and oxidative stress in the hippocampus of in-utero cocaine-exposed rats. Neuroreport 16 (2005) 1217-1221
3. Bashkatova V., Meunier J., Vanin A., and Maurice T. Nitric oxide and oxidative stress in the brain of rats exposed in utero to cocaine. Ann N Y Acad Sci 1074 (2006) 632-642
4. Beckman J.S. Oxidative damage and tyrosine nitration from peroxynitrite. Chem Res Toxicol 9 (1996) 836-844
5. Beit-Yannai E., Kohen R., Horowitz M., Trembovler V., and Shohami E. Changes of biological reducing activity in rat brain following closed head injury: a cyclic voltammetry study in normal and heat-acclimated rats. J Cereb Blood Flow Metab 17 (1997) 273-279
6. Beit-Yannai E., Zhang R., Trembovler V., Samuni A., and Shohami E. Cerebroprotective effect of stable nitroxide radicals in closed head injury in the rat. Brain Res 717 (1996) 22-28
7. Benzie I.F., and Strain J.J. The ferric reducing ability of plasma (FRAP) as a measure of "antioxidant power": the FRAP assay. Anal Biochem 239 (1996) 70-76
8. Berridge K.C., and Robinson T.E. What is the role of dopamine in reward: hedonic impact, reward learning, or incentive salience?. Brain Res Brain Res Rev 28 (1998) 309-369
9. Boelsterli U.A., and Goldlin C. Biomechanisms of cocaine-induced hepatocyte injury mediated by the formation of reactive metabolites. Arch Toxicol 65 (1991) 351-360
10. Bradford M.M. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 72 (1976) 248-254
11. Cao G., Verdon C.P., Wu A.H., Wang H., and Prior R.L. Automated assay of oxygen radical absorbance capacity with the COBAS FARA II. Clin Chem 41 (1995) 1738-1744
12. Dietrich J.B., Mangeol A., Revel M.O., Burgun C., Aunis D., and Zwiller J. Acute or repeated cocaine administration generates reactive oxygen species and induces antioxidant enzyme activity in dopaminergic rat brain structures. Neuropharmacology 48 (2005) 965-974
13. Fineschi V., Baroldi G., Centini F., Cerretani D., Fiaschi A.I., Micheli L., Parolini M., Turillazzi E., and Giorgi G. Markers of cardiac oxidative stress and altered morphology after intraperitoneal cocaine injection in a rat model. Int J Legal Med 114 (2001) 323-330
14. Fraschini C., and Vignon M.R. Selective oxidation of primary alcohol groups of beta-cyclodextrin mediated by 2,2,6,6-tetramethylpiperidine-1-oxyl radical (TEMPO). Carbohydr Res 328 (2000) 585-589
15. Gilgun-Sherki Y., Melamed E., and Offen D. Oxidative stress induced-neurodegenerative diseases: the need for antioxidants that penetrate the blood brain barrier. Neuropharmacology 40 (2001) 959-975
16. Gilgun-Sherki Y., Rosenbaum Z., Melamed E., and Offen D. Antioxidant therapy in acute central nervous system injury: current state. Pharmacol Rev 54 (2002) 271-284
17. Girault J.A., Valjent E., Caboche J., and Herve D. ERK2: a logical AND gate critical for drug-induced plasticity?. Curr Opin Pharmacol 7 (2007) 77-85
18. Glantz L., Avramovich A., Trembovler V., Gurvitz V., Kohen R., Eidelman L.A., and Shohami E. Ischemic preconditioning increases antioxidants in the brain and peripheral organs after cerebral ischemia. Exp Neurol 192 (2005) 117-124
19. Hahn S.M., Lepinski D.L., DeLuca A.M., Mitchell J.B., and Pellmar T.C. Neurophysiological consequences of nitroxide antioxidants. Can J Physiol Pharmacol 73 (1995) 399-403
20. Hahn S.M., Tochner Z., Krishna C.M., Glass J., Wilson L., Samuni A., Sprague M., Venzon D., Glatstein E., Mitchell J.B., et al. Tempol, a stable free radical, is a novel murine radiation protector. Cancer Res 52 (1992) 1750-1753
21. Halliwell B., Zhao K., and Whiteman M. Nitric oxide and peroxynitrite. The ugly, the uglier and the not so good: a personal view of recent controversies. Free Radic Res 31 (1999) 651-669
22. Hermida-Ameijeiras A., Mendez-Alvarez E., Sanchez-Iglesias S., Sanmartin-Suarez C., and Soto-Otero R. Autoxidation and MAO-mediated metabolism of dopamine as a potential cause of oxidative stress: role of ferrous and ferric ions. Neurochem Int 45 (2004) 103-116
23. Israeli A., Patt M., Oron M., Samuni A., Kohen R., and Goldstein S. Kinetics and mechanism of the comproportionation reaction between oxoammonium cation and hydroxylamine derived from cyclic nitroxides. Free Radic Biol Med 38 (2005) 317-324
24. Karmeli F., Eliakim R., Okon E., Samuni A., and Rachmilewitz D. A stable nitroxide radical effectively decreases mucosal damage in experimental colitis. Gut 37 (1995) 386-393
25. Kloss M.W., Rosen G.M., and Rauckman E.J. Biotransformation of norcocaine to norcocaine nitroxide by rat brain microsomes. Psychopharmacology (Berl) 84 (1984) 221-224
26. Kloss M.W., Rosen G.M., and Rauckman E.J. Cocaine-mediated hepatotoxicity. A critical review. Biochem Pharmacol 33 (1984) 169-173
27. Kovacic P. Role of oxidative metabolites of cocaine in toxicity and addiction: oxidative stress and electron transfer. Med Hypotheses 64 (2005) 350-356
28. Kunz W.S., Kuznetsov A.V., Clark J.F., Tracey I., and Elger C.E. Metabolic consequences of the cytochrome c oxidase deficiency in brain of copper-deficient Mo(vbr) mice. J Neurochem 72 (1999) 1580-1585
29. Kwon T.H., Chao D.L., Malloy K., Sun D., Alessandri B., and Bullock M.R. Tempol, a novel stable nitroxide, reduces brain damage and free radical production, after acute subdural hematoma in the rat. J Neurotrauma 20 (2003) 337-345
30. Lander H.M., Milbank A.J., Tauras J.M., Hajjar D.P., Hempstead B.L., Schwartz G.D., Kraemer R.T., Mirza U.A., Chait B.T., Burk S.C., and Quilliam L.A. Redox regulation of cell signalling. Nature 381 (1996) 380-381
31. Liang Q., Smith A.D., Pan S., Tyurin V.A., Kagan V.E., Hastings T.G., and Schor N.F. Neuroprotective effects of TEMPOL in central and peripheral nervous system models of Parkinson's disease. Biochem Pharmacol 70 (2005) 1371-1381
32. Lu L., Koya E., Zhai H., Hope B.T., and Shaham Y. Role of ERK in cocaine addiction. Trends Neurosci 29 (2006) 695-703
33. McCubrey J.A., Lahair M.M., and Franklin R.A. Reactive oxygen species-induced activation of the MAP kinase signaling pathways. Antioxid Redox Signal 8 (2006) 1775-1789
34. Misko T.P., Schilling R.J., Salvemini D., Moore W.M., and Currie M.G. A fluorometric assay for the measurement of nitrite in biological samples. Anal Biochem 214 (1993) 11-16
35. Moor E., Kohen R., Reiter R.J., and Shohami E. Closed head injury increases extracellular levels of antioxidants in rat hippocampus in vivo: an adaptive mechanism?. Neurosci Lett 316 (2001) 169-172
36. Moritz F., Monteil C., Mulder P., Derumeaux G., Bizet C., Renet S., Lallemand F., Richard V., and Thuillez C. Prolonged cardiac dysfunction after withdrawal of chronic cocaine exposure in rats. J Cardiovasc Pharmacol 42 (2003) 642-647
37. Ndikum-Moffor F.M., Schoeb T.R., and Roberts S.M. Liver toxicity from norcocaine nitroxide, an N-oxidative metabolite of cocaine. J Pharmacol Exp Ther 284 (1998) 413-419
38. Nestler E.J. Historical review: Molecular and cellular mechanisms of opiate and cocaine addiction. Trends Pharmacol Sci 25 (2004) 210-218
39. Niehaus Jr. W.G., and Samuelsson B. Formation of malonaldehyde from phospholipid arachidonate during microsomal lipid peroxidation. Eur J Biochem 6 (1968) 126-130
40. Nishiyama A., Yoshizumi M., Hitomi H., Kagami S., Kondo S., Miyatake A., Fukunaga M., Tamaki T., Kiyomoto H., Kohno M., Shokoji T., Kimura S., and Abe Y. The SOD mimetic tempol ameliorates glomerular injury and reduces mitogen-activated protein kinase activity in Dahl salt-sensitive rats. J Am Soc Nephrol 15 (2004) 306-315
41. Ornoy A., Zaken V., and Kohen R. Role of reactive oxygen species (ROS) in the diabetes-induced anomalies in rat embryos in vitro: reduction in antioxidant enzymes and low-molecular-weight antioxidants (LMWA) may be the causative factor for increased anomalies. Teratology 60 (1999) 376-386
42. Prior R.L., Hoang H., Gu L., Wu X., Bacchiocca M., Howard L., Hampsch-Woodill M., Huang D., Ou B., and Jacob R. Assays for hydrophilic and lipophilic antioxidant capacity (oxygen radical absorbance capacity (ORAC(FL))) of plasma and other biological and food samples. J Agric Food Chem 51 (2003) 3273-3279
43. Rak R., Chao D.L., Pluta R.M., Mitchell J.B., Oldfield E.H., and Watson J.C. Neuroprotection by the stable nitroxide tempol during reperfusion in a rat model of transient focal ischemia. J Neurosurg 92 (2000) 646-651
44. Rao R.K., and Clayton L.W. Regulation of protein phosphatase 2A by hydrogen peroxide and glutathionylation. Biochem Biophys Res Commun 293 (2002) 610-616
45. Samuni A., Krishna C.M., Riesz P., Finkelstein E., and Russo A. A novel metal-free low molecular weight superoxide dismutase mimic. J Biol Chem 263 (1988) 17921-17924
46. Smythies J., and Galzigna L. The oxidative metabolism of catecholamines in the brain: a review. Biochim Biophys Acta 1380 (1998) 159-162
47. Soule B.P., Hyodo F., Matsumoto K., Simone N.L., Cook J.A., Krishna M.C., and Mitchell J.B. The chemistry and biology of nitroxide compounds. Free Radic Biol Med 42 (2007) 1632-1650
48. Thiemermann C. Membrane-permeable radical scavengers (tempol) for shock, ischemia-reperfusion injury, and inflammation. Crit Care Med 31 (2003) S76-S84
49. Torres M., and Forman H.J. Redox signaling and the MAP kinase pathways. Biofactors 17 (2003) 287-296
50. Vetulani J. Drug addiction. Part II. Neurobiology of addiction. Pol J Pharmacol 53 (2001) 303-317
51. Wink D.A., Miranda K.M., Espey M.G., Pluta R.M., Hewett S.J., Colton C., Vitek M., Feelisch M., and Grisham M.B. Mechanisms of the antioxidant effects of nitric oxide. Antioxid Redox Signal 3 (2001) 203-213
52. Wise R.A. Addictive drugs and brain stimulation reward. Annu Rev Neurosci 19 (1996) 319-340
53. Zeltcer G., Berenshtein E., Samuni A., and Chevion M. Nitroxide radicals prevent metal-aggravated reperfusion injury in isolated rat heart. Free Radic Res 27 (1997) 627-635